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Network neighborhood for query Sequence : LPP3_HUMAN

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LPP3_HUMAN
SwissProt Accessions	O14495, Q96GW0, Q99782	Gene names	PPAP2B, LPP3
Domain Architecture
Description	Lipid phosphate phosphohydrolase 3 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2b) (Phosphatidate phosphohydrolase type 2b) (PAP2b) (PAP- 2b) (PAP2-beta) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LPP3_HUMAN
θ value	1.66873e-171 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	O14495, Q96GW0, Q99782	Gene names	PPAP2B, LPP3
Domain Architecture
Description	Lipid phosphate phosphohydrolase 3 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2b) (Phosphatidate phosphohydrolase type 2b) (PAP2b) (PAP- 2b) (PAP2-beta) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP).

LPP3_MOUSE
θ value	1.56551e-161 (rank : 2)	NC score	0.998877 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	11
SwissProt Accessions	Q99JY8, Q3TVM4, Q3TXR7, Q8BTB7	Gene names	Ppap2b, Lpp3
Domain Architecture
Description	Lipid phosphate phosphohydrolase 3 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2b) (Phosphatidate phosphohydrolase type 2b) (PAP2b) (PAP- 2b) (PAP2-beta).

LPP1_MOUSE
θ value	1.7756e-72 (rank : 3)	NC score	0.967699 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q61469, Q61690, Q8BPB8	Gene names	Ppap2a, Hpic53, Lpp1
Domain Architecture
Description	Lipid phosphate phosphohydrolase 1 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2a) (Phosphatidate phosphohydrolase type 2a) (PAP2a) (PAP- 2a) (PAP2-alpha) (Hydrogen peroxide-inducible protein 53) (Hic53) (35 kDa PAP) (mPAP).

LPP1_HUMAN
θ value	2.17053e-70 (rank : 4)	NC score	0.967498 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O14494, O60457, O60463	Gene names	PPAP2A, LPP1
Domain Architecture
Description	Lipid phosphate phosphohydrolase 1 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2a) (Phosphatidate phosphohydrolase type 2a) (PAP2a) (PAP- 2a) (PAP2-alpha).

LPP2_MOUSE
θ value	7.71989e-68 (rank : 5)	NC score	0.965964 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DAX2, Q9WUA4	Gene names	Ppap2c, Lpp2
Domain Architecture
Description	Lipid phosphate phosphohydrolase 2 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2c) (Phosphatidate phosphohydrolase type 2c) (PAP2c) (PAP- 2c) (PAP2-gamma) (PAP2-G).

LPP2_HUMAN
θ value	1.50663e-63 (rank : 6)	NC score	0.962235 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	O43688	Gene names	PPAP2C, LPP2
Domain Architecture
Description	Lipid phosphate phosphohydrolase 2 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2c) (Phosphatidate phosphohydrolase type 2c) (PAP2c) (PAP- 2c) (PAP2-gamma) (PAP2-G).

PPAC3_HUMAN
θ value	0.0563607 (rank : 7)	NC score	0.134572 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NBV4, Q5T6P0, Q96SS7, Q9BRC3	Gene names	PPAPDC3, C9orf67
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

PPAC3_MOUSE
θ value	0.0563607 (rank : 8)	NC score	0.126130 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WB2	Gene names	Ppapdc3
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

DOPP1_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.151559 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YN1, Q96GF8	Gene names	DOLPP1
Domain Architecture
Description	Dolichyldiphosphatase 1 (EC 3.6.1.43) (Dolichyl pyrophosphate phosphatase 1).

PPAC2_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.095610 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D4F2	Gene names	Ppapdc2
Domain Architecture	No domain graphic available
Description	Presqualene diphosphate phosphatase (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 2).

PPAC2_HUMAN
θ value	1.81305 (rank : 11)	NC score	0.088338 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IY26, Q5JVJ6, Q8NCK9	Gene names	PPAPDC2
Domain Architecture	No domain graphic available
Description	Presqualene diphosphate phosphatase (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 2).

DOPP1_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.106797 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMF7, Q8BN02, Q8R0P7, Q9CRF2	Gene names	Dolpp1
Domain Architecture
Description	Dolichyldiphosphatase 1 (EC 3.6.1.43) (Dolichyl pyrophosphate phosphatase 1) (Protein 2-23).

EDG5_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.005230 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	721	Shared Neighborhood Hits	3
SwissProt Accessions	P52592, Q9R236	Gene names	Edg5, Gpcr13, Lpb2
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-5 (S1P receptor Edg-5) (Lysophospholipid receptor B2) (Endothelial differentiation G-protein coupled receptor 5) (Sphingosine 1-phosphate receptor 2) (S1P2).

Hits sorted by NC score

LPP3_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.66873e-171 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	O14495, Q96GW0, Q99782	Gene names	PPAP2B, LPP3
Domain Architecture
Description	Lipid phosphate phosphohydrolase 3 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2b) (Phosphatidate phosphohydrolase type 2b) (PAP2b) (PAP- 2b) (PAP2-beta) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP).

LPP3_MOUSE
NC score	0.998877 (rank : 2)	θ value	1.56551e-161 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	11
SwissProt Accessions	Q99JY8, Q3TVM4, Q3TXR7, Q8BTB7	Gene names	Ppap2b, Lpp3
Domain Architecture
Description	Lipid phosphate phosphohydrolase 3 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2b) (Phosphatidate phosphohydrolase type 2b) (PAP2b) (PAP- 2b) (PAP2-beta).

LPP1_MOUSE
NC score	0.967699 (rank : 3)	θ value	1.7756e-72 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q61469, Q61690, Q8BPB8	Gene names	Ppap2a, Hpic53, Lpp1
Domain Architecture
Description	Lipid phosphate phosphohydrolase 1 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2a) (Phosphatidate phosphohydrolase type 2a) (PAP2a) (PAP- 2a) (PAP2-alpha) (Hydrogen peroxide-inducible protein 53) (Hic53) (35 kDa PAP) (mPAP).

LPP1_HUMAN
NC score	0.967498 (rank : 4)	θ value	2.17053e-70 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O14494, O60457, O60463	Gene names	PPAP2A, LPP1
Domain Architecture
Description	Lipid phosphate phosphohydrolase 1 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2a) (Phosphatidate phosphohydrolase type 2a) (PAP2a) (PAP- 2a) (PAP2-alpha).

LPP2_MOUSE
NC score	0.965964 (rank : 5)	θ value	7.71989e-68 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DAX2, Q9WUA4	Gene names	Ppap2c, Lpp2
Domain Architecture
Description	Lipid phosphate phosphohydrolase 2 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2c) (Phosphatidate phosphohydrolase type 2c) (PAP2c) (PAP- 2c) (PAP2-gamma) (PAP2-G).

LPP2_HUMAN
NC score	0.962235 (rank : 6)	θ value	1.50663e-63 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	O43688	Gene names	PPAP2C, LPP2
Domain Architecture
Description	Lipid phosphate phosphohydrolase 2 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2c) (Phosphatidate phosphohydrolase type 2c) (PAP2c) (PAP- 2c) (PAP2-gamma) (PAP2-G).

DOPP1_HUMAN
NC score	0.151559 (rank : 7)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YN1, Q96GF8	Gene names	DOLPP1
Domain Architecture
Description	Dolichyldiphosphatase 1 (EC 3.6.1.43) (Dolichyl pyrophosphate phosphatase 1).

PPAC3_HUMAN
NC score	0.134572 (rank : 8)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NBV4, Q5T6P0, Q96SS7, Q9BRC3	Gene names	PPAPDC3, C9orf67
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

PPAC3_MOUSE
NC score	0.126130 (rank : 9)	θ value	0.0563607 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WB2	Gene names	Ppapdc3
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

DOPP1_MOUSE
NC score	0.106797 (rank : 10)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMF7, Q8BN02, Q8R0P7, Q9CRF2	Gene names	Dolpp1
Domain Architecture
Description	Dolichyldiphosphatase 1 (EC 3.6.1.43) (Dolichyl pyrophosphate phosphatase 1) (Protein 2-23).

PPAC2_MOUSE
NC score	0.095610 (rank : 11)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D4F2	Gene names	Ppapdc2
Domain Architecture	No domain graphic available
Description	Presqualene diphosphate phosphatase (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 2).

PPAC2_HUMAN
NC score	0.088338 (rank : 12)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IY26, Q5JVJ6, Q8NCK9	Gene names	PPAPDC2
Domain Architecture	No domain graphic available
Description	Presqualene diphosphate phosphatase (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 2).

EDG5_MOUSE
NC score	0.005230 (rank : 13)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	721	Shared Neighborhood Hits	3
SwissProt Accessions	P52592, Q9R236	Gene names	Edg5, Gpcr13, Lpb2
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-5 (S1P receptor Edg-5) (Lysophospholipid receptor B2) (Endothelial differentiation G-protein coupled receptor 5) (Sphingosine 1-phosphate receptor 2) (S1P2).