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Network neighborhood for query Sequence : PFTA_HUMAN

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PFTA_HUMAN
SwissProt Accessions	P49354, Q9UDC1	Gene names	FNTA
Domain Architecture
Description	Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase alpha subunit) (Ras proteins prenyltransferase alpha) (FTase-alpha) (Type I protein geranyl-geranyltransferase alpha subunit) (GGTase-I-alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PFTA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P49354, Q9UDC1	Gene names	FNTA
Domain Architecture
Description	Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase alpha subunit) (Ras proteins prenyltransferase alpha) (FTase-alpha) (Type I protein geranyl-geranyltransferase alpha subunit) (GGTase-I-alpha).

PFTA_MOUSE
θ value	2.83983e-179 (rank : 2)	NC score	0.996226 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q61239, Q921F7	Gene names	Fnta
Domain Architecture
Description	Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase alpha subunit) (Ras proteins prenyltransferase alpha) (FTase-alpha) (Type I protein geranyl-geranyltransferase alpha subunit) (GGTase-I-alpha).

PGTA_MOUSE
θ value	1.99529e-15 (rank : 3)	NC score	0.484960 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JHK4, Q9JLX2	Gene names	Rabggta
Domain Architecture
Description	Geranylgeranyl transferase type-2 alpha subunit (EC 2.5.1.60) (Geranylgeranyl transferase type II alpha subunit) (Rab geranylgeranyltransferase alpha subunit) (Rab geranyl- geranyltransferase alpha subunit) (Rab GG transferase alpha) (Rab GGTase alpha).

PGTA_HUMAN
θ value	7.58209e-15 (rank : 4)	NC score	0.468988 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	160	Shared Neighborhood Hits	5
SwissProt Accessions	Q92696	Gene names	RABGGTA
Domain Architecture
Description	Geranylgeranyl transferase type-2 alpha subunit (EC 2.5.1.60) (Geranylgeranyl transferase type II alpha subunit) (Rab geranylgeranyltransferase alpha subunit) (Rab geranyl- geranyltransferase alpha subunit) (Rab GG transferase alpha) (Rab GGTase alpha).

CUL3_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.041096 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q13618, O75415, Q569L3, Q9UBI8, Q9UET7	Gene names	CUL3, KIAA0617
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL3_MOUSE
θ value	0.813845 (rank : 6)	NC score	0.041105 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLV5	Gene names	Cul3
Domain Architecture
Description	Cullin-3 (CUL-3).

CDC27_HUMAN
θ value	1.06291 (rank : 7)	NC score	0.060012 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	139	Shared Neighborhood Hits	4
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

TTC7B_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.032804 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q86TV6, Q86U24, Q86VT3	Gene names	TTC7B, TTC7L1
Domain Architecture
Description	Tetratricopeptide repeat protein 7B (Tetratricopeptide repeat protein 7-like-1).

CRNL1_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.028131 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	P63154, Q542E8, Q9CQC1	Gene names	Crnkl1
Domain Architecture	No domain graphic available
Description	Crooked neck-like protein 1 (Crooked neck homolog).

TCAL8_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.027713 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZY2, Q9CYP9	Gene names	Tceal8
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 8 (TCEA-like protein 8) (Transcription elongation factor S-II protein-like 8).

ATX1_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.016346 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

CRNL1_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.027047 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZJ0, Q5JY64, Q8WYI5, Q9BZI9, Q9BZJ1, Q9BZJ2, Q9GZW7, Q9H8F8, Q9NQH5, Q9NYD8	Gene names	CRNKL1, CRN
Domain Architecture
Description	Crooked neck-like protein 1 (Crooked neck homolog) (hCrn).

KTN1_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.007664 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	1197	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

PHLPP_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.024148 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	604	Shared Neighborhood Hits	5
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

Hits sorted by NC score

PFTA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P49354, Q9UDC1	Gene names	FNTA
Domain Architecture
Description	Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase alpha subunit) (Ras proteins prenyltransferase alpha) (FTase-alpha) (Type I protein geranyl-geranyltransferase alpha subunit) (GGTase-I-alpha).

PFTA_MOUSE
NC score	0.996226 (rank : 2)	θ value	2.83983e-179 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q61239, Q921F7	Gene names	Fnta
Domain Architecture
Description	Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase alpha subunit) (Ras proteins prenyltransferase alpha) (FTase-alpha) (Type I protein geranyl-geranyltransferase alpha subunit) (GGTase-I-alpha).

PGTA_MOUSE
NC score	0.484960 (rank : 3)	θ value	1.99529e-15 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JHK4, Q9JLX2	Gene names	Rabggta
Domain Architecture
Description	Geranylgeranyl transferase type-2 alpha subunit (EC 2.5.1.60) (Geranylgeranyl transferase type II alpha subunit) (Rab geranylgeranyltransferase alpha subunit) (Rab geranyl- geranyltransferase alpha subunit) (Rab GG transferase alpha) (Rab GGTase alpha).

PGTA_HUMAN
NC score	0.468988 (rank : 4)	θ value	7.58209e-15 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	160	Shared Neighborhood Hits	5
SwissProt Accessions	Q92696	Gene names	RABGGTA
Domain Architecture
Description	Geranylgeranyl transferase type-2 alpha subunit (EC 2.5.1.60) (Geranylgeranyl transferase type II alpha subunit) (Rab geranylgeranyltransferase alpha subunit) (Rab geranyl- geranyltransferase alpha subunit) (Rab GG transferase alpha) (Rab GGTase alpha).

CDC27_HUMAN
NC score	0.060012 (rank : 5)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	139	Shared Neighborhood Hits	4
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

CUL3_MOUSE
NC score	0.041105 (rank : 6)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLV5	Gene names	Cul3
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL3_HUMAN
NC score	0.041096 (rank : 7)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q13618, O75415, Q569L3, Q9UBI8, Q9UET7	Gene names	CUL3, KIAA0617
Domain Architecture
Description	Cullin-3 (CUL-3).

TTC7B_HUMAN
NC score	0.032804 (rank : 8)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q86TV6, Q86U24, Q86VT3	Gene names	TTC7B, TTC7L1
Domain Architecture
Description	Tetratricopeptide repeat protein 7B (Tetratricopeptide repeat protein 7-like-1).

CRNL1_MOUSE
NC score	0.028131 (rank : 9)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	P63154, Q542E8, Q9CQC1	Gene names	Crnkl1
Domain Architecture	No domain graphic available
Description	Crooked neck-like protein 1 (Crooked neck homolog).

TCAL8_MOUSE
NC score	0.027713 (rank : 10)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZY2, Q9CYP9	Gene names	Tceal8
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 8 (TCEA-like protein 8) (Transcription elongation factor S-II protein-like 8).

CRNL1_HUMAN
NC score	0.027047 (rank : 11)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZJ0, Q5JY64, Q8WYI5, Q9BZI9, Q9BZJ1, Q9BZJ2, Q9GZW7, Q9H8F8, Q9NQH5, Q9NYD8	Gene names	CRNKL1, CRN
Domain Architecture
Description	Crooked neck-like protein 1 (Crooked neck homolog) (hCrn).

PHLPP_HUMAN
NC score	0.024148 (rank : 12)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	604	Shared Neighborhood Hits	5
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

ATX1_MOUSE
NC score	0.016346 (rank : 13)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

KTN1_HUMAN
NC score	0.007664 (rank : 14)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	1197	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).