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Network neighborhood for query Sequence : PERL_HUMAN

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PERL_HUMAN
SwissProt Accessions	P22079, Q13408	Gene names	LPO, SAPX
Domain Architecture
Description	Lactoperoxidase precursor (EC 1.11.1.7) (LPO) (Salivary peroxidase) (SPO).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PERE_HUMAN
θ value	0 (rank : 1)	NC score	0.990515 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	P11678, Q4TVP3	Gene names	EPX, EPER, EPO, EPP
Domain Architecture
Description	Eosinophil peroxidase precursor (EC 1.11.1.7) (EPO) [Contains: Eosinophil peroxidase light chain; Eosinophil peroxidase heavy chain].

PERE_MOUSE
θ value	0 (rank : 2)	NC score	0.989455 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	P49290, Q61798	Gene names	Epx, Eper
Domain Architecture
Description	Eosinophil peroxidase precursor (EC 1.11.1.7) (EPO) [Contains: Eosinophil peroxidase light chain; Eosinophil peroxidase heavy chain].

PERL_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	P22079, Q13408	Gene names	LPO, SAPX
Domain Architecture
Description	Lactoperoxidase precursor (EC 1.11.1.7) (LPO) (Salivary peroxidase) (SPO).

PERM_HUMAN
θ value	0 (rank : 4)	NC score	0.991810 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	P05164, Q14862, Q4PJH5	Gene names	MPO
Domain Architecture
Description	Myeloperoxidase precursor (EC 1.11.1.7) (MPO) [Contains: 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain].

PERM_MOUSE
θ value	0 (rank : 5)	NC score	0.992369 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	P11247	Gene names	Mpo
Domain Architecture
Description	Myeloperoxidase precursor (EC 1.11.1.7) (MPO) [Contains: Myeloperoxidase light chain; Myeloperoxidase heavy chain].

PERT_HUMAN
θ value	1.91815e-151 (rank : 6)	NC score	0.851853 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	221	Shared Neighborhood Hits	13
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	2.12077e-150 (rank : 7)	NC score	0.859008 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	221	Shared Neighborhood Hits	13
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

DUOX1_HUMAN
θ value	1.73987e-27 (rank : 8)	NC score	0.514553 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRD9, Q6ZMB3, Q6ZR09, Q9NZC1	Gene names	DUOX1, DUOX, LNOX1, THOX1
Domain Architecture	No domain graphic available
Description	Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1) (Long NOX 1).

DUOX2_HUMAN
θ value	4.28545e-26 (rank : 9)	NC score	0.505885 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	139	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRD8, Q9NR02, Q9UHF9	Gene names	DUOX2, LNOX2, THOX2
Domain Architecture	No domain graphic available
Description	Dual oxidase 2 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase p138-tox) (p138 thyroid oxidase) (Large NOX 2) (Long NOX 2).

PGH1_MOUSE
θ value	1.69304e-06 (rank : 10)	NC score	0.308215 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH1_HUMAN
θ value	8.40245e-06 (rank : 11)	NC score	0.301236 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_MOUSE
θ value	4.1701e-05 (rank : 12)	NC score	0.280586 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PGH2_HUMAN
θ value	7.1131e-05 (rank : 13)	NC score	0.293475 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	103	Shared Neighborhood Hits	13
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

ITSN1_MOUSE
θ value	0.21417 (rank : 14)	NC score	0.008987 (rank : 25)
Query Neighborhood Hits	24	Target Neighborhood Hits	1669	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

PPAL_MOUSE
θ value	1.81305 (rank : 15)	NC score	0.018623 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P24638, Q8QZT5	Gene names	Acp2
Domain Architecture
Description	Lysosomal acid phosphatase precursor (EC 3.1.3.2) (LAP).

MCM4_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.008913 (rank : 26)
Query Neighborhood Hits	24	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	P33991, Q8NEH1, Q99658	Gene names	MCM4, CDC21
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

TERF1_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.016402 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	P54274, Q15553, Q93029	Gene names	TERF1, PIN2, TRF, TRF1
Domain Architecture
Description	Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1) (NIMA-interacting protein 2) (Telomeric protein Pin2/TRF1).

ITSN1_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.006028 (rank : 29)
Query Neighborhood Hits	24	Target Neighborhood Hits	1757	Shared Neighborhood Hits	3
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

DHDDS_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.014394 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KU1, Q3UF13, Q8BZ16, Q8BZK8	Gene names	Dhdds
Domain Architecture
Description	Dehydrodolichyl diphosphate synthase (EC 2.5.1.-) (Dedol-PP synthase).

DLGP2_MOUSE
θ value	6.88961 (rank : 20)	NC score	0.007242 (rank : 28)
Query Neighborhood Hits	24	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).

OL490_MOUSE
θ value	6.88961 (rank : 21)	NC score	-0.001630 (rank : 32)
Query Neighborhood Hits	24	Target Neighborhood Hits	691	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VFD2	Gene names	Olfr490, Mor204-17
Domain Architecture
Description	Olfactory receptor 490 (Olfactory receptor 204-17).

IGF1R_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.001297 (rank : 31)
Query Neighborhood Hits	24	Target Neighborhood Hits	977	Shared Neighborhood Hits	5
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	8.99809 (rank : 23)	NC score	0.001305 (rank : 30)
Query Neighborhood Hits	24	Target Neighborhood Hits	973	Shared Neighborhood Hits	5
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

K1683_HUMAN
θ value	8.99809 (rank : 24)	NC score	0.008319 (rank : 27)
Query Neighborhood Hits	24	Target Neighborhood Hits	240	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

CY24B_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.069510 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P04839, Q2PP16	Gene names	CYBB, NOX2
Domain Architecture
Description	Cytochrome b-245 heavy chain (p22 phagocyte B-cytochrome) (Neutrophil cytochrome b 91 kDa polypeptide) (CGD91-phox) (gp91-phox) (gp91-1) (Heme-binding membrane glycoprotein gp91phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Superoxide-generating NADPH oxidase heavy chain subunit) (NADPH oxidase 2).

CY24B_MOUSE
θ value	θ > 10 (rank : 26)	NC score	0.069437 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q61093	Gene names	Cybb, Cgd
Domain Architecture
Description	Cytochrome b-245 heavy chain (p22 phagocyte B-cytochrome) (Neutrophil cytochrome b 91 kDa polypeptide) (CGD91-phox) (gp91-phox) (gp91-1) (Heme-binding membrane glycoprotein gp91phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta).

NOX1_HUMAN
θ value	θ > 10 (rank : 27)	NC score	0.073966 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5S8, O95691, Q2PP02	Gene names	NOX1, NOH1
Domain Architecture
Description	NADPH oxidase homolog 1 (NOX-1) (NOH-1) (NADH/NADPH mitogenic oxidase subunit P65-MOX) (Mitogenic oxidase 1) (MOX1).

NOX3_HUMAN
θ value	θ > 10 (rank : 28)	NC score	0.075397 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBY0, Q9HBJ9	Gene names	NOX3, MOX2
Domain Architecture	No domain graphic available
Description	NADPH oxidase 3 (EC 1.6.3.-) (gp91phox homolog 3) (GP91-3) (Mitogenic oxidase 2).

NOX3_MOUSE
θ value	θ > 10 (rank : 29)	NC score	0.073711 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q672J9, Q6Y4Q8	Gene names	Nox3
Domain Architecture	No domain graphic available
Description	NADPH oxidase 3 (EC 1.6.3.-).

NOX4_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.064759 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPH5, Q5K3R4, Q5K3R5, Q5K3R6, Q5K3R8, Q7Z7G3, Q86V92	Gene names	NOX4, RENOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase 4 (EC 1.6.3.-) (Kidney superoxide-producing NADPH oxidase) (KOX-1) (Renal NAD(P)H-oxidase).

NOX4_MOUSE
θ value	θ > 10 (rank : 31)	NC score	0.066152 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHI8, Q3TF39, Q8C3M1, Q8VCA3	Gene names	Nox4, Renox
Domain Architecture	No domain graphic available
Description	NADPH oxidase 4 (EC 1.6.3.-) (Kidney superoxide-producing NADPH oxidase) (Kox-1) (Renal NAD(P)H-oxidase) (Superoxide-generating NADPH oxidase 4).

NOX5_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.086606 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PH1, Q8TEQ1, Q8TER4, Q96PH2, Q96PJ8, Q96PJ9, Q9H6E0, Q9HAM8	Gene names	NOX5
Domain Architecture	No domain graphic available
Description	NADPH oxidase 5 (EC 1.6.3.-).

Hits sorted by NC score

PERL_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	P22079, Q13408	Gene names	LPO, SAPX
Domain Architecture
Description	Lactoperoxidase precursor (EC 1.11.1.7) (LPO) (Salivary peroxidase) (SPO).

PERM_MOUSE
NC score	0.992369 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	P11247	Gene names	Mpo
Domain Architecture
Description	Myeloperoxidase precursor (EC 1.11.1.7) (MPO) [Contains: Myeloperoxidase light chain; Myeloperoxidase heavy chain].

PERM_HUMAN
NC score	0.991810 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	P05164, Q14862, Q4PJH5	Gene names	MPO
Domain Architecture
Description	Myeloperoxidase precursor (EC 1.11.1.7) (MPO) [Contains: 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain].

PERE_HUMAN
NC score	0.990515 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	P11678, Q4TVP3	Gene names	EPX, EPER, EPO, EPP
Domain Architecture
Description	Eosinophil peroxidase precursor (EC 1.11.1.7) (EPO) [Contains: Eosinophil peroxidase light chain; Eosinophil peroxidase heavy chain].

PERE_MOUSE
NC score	0.989455 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	P49290, Q61798	Gene names	Epx, Eper
Domain Architecture
Description	Eosinophil peroxidase precursor (EC 1.11.1.7) (EPO) [Contains: Eosinophil peroxidase light chain; Eosinophil peroxidase heavy chain].

PERT_MOUSE
NC score	0.859008 (rank : 6)	θ value	2.12077e-150 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	221	Shared Neighborhood Hits	13
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_HUMAN
NC score	0.851853 (rank : 7)	θ value	1.91815e-151 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	221	Shared Neighborhood Hits	13
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

DUOX1_HUMAN
NC score	0.514553 (rank : 8)	θ value	1.73987e-27 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRD9, Q6ZMB3, Q6ZR09, Q9NZC1	Gene names	DUOX1, DUOX, LNOX1, THOX1
Domain Architecture	No domain graphic available
Description	Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1) (Long NOX 1).

DUOX2_HUMAN
NC score	0.505885 (rank : 9)	θ value	4.28545e-26 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	139	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRD8, Q9NR02, Q9UHF9	Gene names	DUOX2, LNOX2, THOX2
Domain Architecture	No domain graphic available
Description	Dual oxidase 2 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase p138-tox) (p138 thyroid oxidase) (Large NOX 2) (Long NOX 2).

PGH1_MOUSE
NC score	0.308215 (rank : 10)	θ value	1.69304e-06 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH1_HUMAN
NC score	0.301236 (rank : 11)	θ value	8.40245e-06 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_HUMAN
NC score	0.293475 (rank : 12)	θ value	7.1131e-05 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	103	Shared Neighborhood Hits	13
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
NC score	0.280586 (rank : 13)	θ value	4.1701e-05 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

NOX5_HUMAN
NC score	0.086606 (rank : 14)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	24	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PH1, Q8TEQ1, Q8TER4, Q96PH2, Q96PJ8, Q96PJ9, Q9H6E0, Q9HAM8	Gene names	NOX5
Domain Architecture	No domain graphic available
Description	NADPH oxidase 5 (EC 1.6.3.-).

NOX3_HUMAN
NC score	0.075397 (rank : 15)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBY0, Q9HBJ9	Gene names	NOX3, MOX2
Domain Architecture	No domain graphic available
Description	NADPH oxidase 3 (EC 1.6.3.-) (gp91phox homolog 3) (GP91-3) (Mitogenic oxidase 2).

NOX1_HUMAN
NC score	0.073966 (rank : 16)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	24	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5S8, O95691, Q2PP02	Gene names	NOX1, NOH1
Domain Architecture
Description	NADPH oxidase homolog 1 (NOX-1) (NOH-1) (NADH/NADPH mitogenic oxidase subunit P65-MOX) (Mitogenic oxidase 1) (MOX1).

NOX3_MOUSE
NC score	0.073711 (rank : 17)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q672J9, Q6Y4Q8	Gene names	Nox3
Domain Architecture	No domain graphic available
Description	NADPH oxidase 3 (EC 1.6.3.-).

CY24B_HUMAN
NC score	0.069510 (rank : 18)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	24	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P04839, Q2PP16	Gene names	CYBB, NOX2
Domain Architecture
Description	Cytochrome b-245 heavy chain (p22 phagocyte B-cytochrome) (Neutrophil cytochrome b 91 kDa polypeptide) (CGD91-phox) (gp91-phox) (gp91-1) (Heme-binding membrane glycoprotein gp91phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Superoxide-generating NADPH oxidase heavy chain subunit) (NADPH oxidase 2).

CY24B_MOUSE
NC score	0.069437 (rank : 19)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q61093	Gene names	Cybb, Cgd
Domain Architecture
Description	Cytochrome b-245 heavy chain (p22 phagocyte B-cytochrome) (Neutrophil cytochrome b 91 kDa polypeptide) (CGD91-phox) (gp91-phox) (gp91-1) (Heme-binding membrane glycoprotein gp91phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta).

NOX4_MOUSE
NC score	0.066152 (rank : 20)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHI8, Q3TF39, Q8C3M1, Q8VCA3	Gene names	Nox4, Renox
Domain Architecture	No domain graphic available
Description	NADPH oxidase 4 (EC 1.6.3.-) (Kidney superoxide-producing NADPH oxidase) (Kox-1) (Renal NAD(P)H-oxidase) (Superoxide-generating NADPH oxidase 4).

NOX4_HUMAN
NC score	0.064759 (rank : 21)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPH5, Q5K3R4, Q5K3R5, Q5K3R6, Q5K3R8, Q7Z7G3, Q86V92	Gene names	NOX4, RENOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase 4 (EC 1.6.3.-) (Kidney superoxide-producing NADPH oxidase) (KOX-1) (Renal NAD(P)H-oxidase).

PPAL_MOUSE
NC score	0.018623 (rank : 22)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P24638, Q8QZT5	Gene names	Acp2
Domain Architecture
Description	Lysosomal acid phosphatase precursor (EC 3.1.3.2) (LAP).

TERF1_HUMAN
NC score	0.016402 (rank : 23)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	P54274, Q15553, Q93029	Gene names	TERF1, PIN2, TRF, TRF1
Domain Architecture
Description	Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1) (NIMA-interacting protein 2) (Telomeric protein Pin2/TRF1).

DHDDS_MOUSE
NC score	0.014394 (rank : 24)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KU1, Q3UF13, Q8BZ16, Q8BZK8	Gene names	Dhdds
Domain Architecture
Description	Dehydrodolichyl diphosphate synthase (EC 2.5.1.-) (Dedol-PP synthase).

ITSN1_MOUSE
NC score	0.008987 (rank : 25)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	1669	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MCM4_HUMAN
NC score	0.008913 (rank : 26)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	P33991, Q8NEH1, Q99658	Gene names	MCM4, CDC21
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

K1683_HUMAN
NC score	0.008319 (rank : 27)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	240	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

DLGP2_MOUSE
NC score	0.007242 (rank : 28)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).

ITSN1_HUMAN
NC score	0.006028 (rank : 29)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	1757	Shared Neighborhood Hits	3
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

IGF1R_MOUSE
NC score	0.001305 (rank : 30)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	973	Shared Neighborhood Hits	5
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_HUMAN
NC score	0.001297 (rank : 31)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	977	Shared Neighborhood Hits	5
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

OL490_MOUSE
NC score	-0.001630 (rank : 32)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	691	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VFD2	Gene names	Olfr490, Mor204-17
Domain Architecture
Description	Olfactory receptor 490 (Olfactory receptor 204-17).