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Network neighborhood for query Sequence : PACA_HUMAN

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PACA_HUMAN
SwissProt Accessions	P18509	Gene names	ADCYAP1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide precursor (PACAP) [Contains: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PACA_MOUSE
θ value	3.23591e-74 (rank : 1)	NC score	0.998195 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	O70176	Gene names	Adcyap1, Pacap
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide precursor (PACAP) [Contains: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)].

PACA_HUMAN
θ value	6.53529e-67 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P18509	Gene names	ADCYAP1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide precursor (PACAP) [Contains: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)].

VIP_MOUSE
θ value	1.58096e-12 (rank : 3)	NC score	0.700545 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	P32648, Q9D2Z7, Q9QUN1	Gene names	Vip
Domain Architecture	No domain graphic available
Description	VIP peptides precursor [Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)].

VIP_HUMAN
θ value	4.59992e-12 (rank : 4)	NC score	0.692451 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	P01282, Q96QK3	Gene names	VIP
Domain Architecture
Description	VIP peptides precursor [Contains: Intestinal peptide PHV-42; Intestinal peptide PHM-27 (Peptide histidine methioninamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)].

SECR_HUMAN
θ value	0.00665767 (rank : 5)	NC score	0.404541 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	P09683	Gene names	SCT
Domain Architecture
Description	Secretin precursor.

SECR_MOUSE
θ value	0.0252991 (rank : 6)	NC score	0.364344 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	Q08535	Gene names	Sct
Domain Architecture
Description	Secretin precursor.

SLIB_HUMAN
θ value	0.0563607 (rank : 7)	NC score	0.321054 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	P01286	Gene names	GHRH, GHRF
Domain Architecture
Description	Somatoliberin precursor (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH) (Somatocrinin) (Somatorelin) (Sermorelin).

GLUC_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.182332 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P01275	Gene names	GCG
Domain Architecture
Description	Glucagon precursor [Contains: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXY) (OXM); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)].

GLUC_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.182082 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P55095, Q3UFE9	Gene names	Gcg
Domain Architecture
Description	Glucagon precursor [Contains: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXY) (OXM); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)].

MA1A1_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.017883 (rank : 11)
Query Neighborhood Hits	10	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P33908, Q9NU44, Q9UJI3	Gene names	MAN1A1
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase).

SLIB_MOUSE
θ value	θ > 10 (rank : 11)	NC score	0.185691 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P16043	Gene names	Ghrh
Domain Architecture
Description	Somatoliberin precursor (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH).

Hits sorted by NC score

PACA_HUMAN
NC score	0.999962 (rank : 1)	θ value	6.53529e-67 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P18509	Gene names	ADCYAP1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide precursor (PACAP) [Contains: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)].

PACA_MOUSE
NC score	0.998195 (rank : 2)	θ value	3.23591e-74 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	O70176	Gene names	Adcyap1, Pacap
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide precursor (PACAP) [Contains: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)].

VIP_MOUSE
NC score	0.700545 (rank : 3)	θ value	1.58096e-12 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	P32648, Q9D2Z7, Q9QUN1	Gene names	Vip
Domain Architecture	No domain graphic available
Description	VIP peptides precursor [Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)].

VIP_HUMAN
NC score	0.692451 (rank : 4)	θ value	4.59992e-12 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	P01282, Q96QK3	Gene names	VIP
Domain Architecture
Description	VIP peptides precursor [Contains: Intestinal peptide PHV-42; Intestinal peptide PHM-27 (Peptide histidine methioninamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)].

SECR_HUMAN
NC score	0.404541 (rank : 5)	θ value	0.00665767 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	P09683	Gene names	SCT
Domain Architecture
Description	Secretin precursor.

SECR_MOUSE
NC score	0.364344 (rank : 6)	θ value	0.0252991 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	Q08535	Gene names	Sct
Domain Architecture
Description	Secretin precursor.

SLIB_HUMAN
NC score	0.321054 (rank : 7)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	P01286	Gene names	GHRH, GHRF
Domain Architecture
Description	Somatoliberin precursor (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH) (Somatocrinin) (Somatorelin) (Sermorelin).

SLIB_MOUSE
NC score	0.185691 (rank : 8)	θ value	θ > 10 (rank : 11)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P16043	Gene names	Ghrh
Domain Architecture
Description	Somatoliberin precursor (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH).

GLUC_HUMAN
NC score	0.182332 (rank : 9)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P01275	Gene names	GCG
Domain Architecture
Description	Glucagon precursor [Contains: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXY) (OXM); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)].

GLUC_MOUSE
NC score	0.182082 (rank : 10)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P55095, Q3UFE9	Gene names	Gcg
Domain Architecture
Description	Glucagon precursor [Contains: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXY) (OXM); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)].

MA1A1_HUMAN
NC score	0.017883 (rank : 11)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P33908, Q9NU44, Q9UJI3	Gene names	MAN1A1
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase).