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Network neighborhood for query Sequence : PA2GX_HUMAN

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PA2GX_HUMAN
SwissProt Accessions	O15496, Q6NT23	Gene names	PLA2G10
Domain Architecture
Description	Group 10 secretory phospholipase A2 precursor (EC 3.1.1.4) (Group X secretory phospholipase A2) (Phosphatidylcholine 2-acylhydrolase GX) (GX sPLA2) (sPLA2-X).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PA2GX_HUMAN
θ value	1.89267e-82 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	O15496, Q6NT23	Gene names	PLA2G10
Domain Architecture
Description	Group 10 secretory phospholipase A2 precursor (EC 3.1.1.4) (Group X secretory phospholipase A2) (Phosphatidylcholine 2-acylhydrolase GX) (GX sPLA2) (sPLA2-X).

PA2GX_MOUSE
θ value	1.04338e-64 (rank : 2)	NC score	0.994285 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	18	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXX3, Q9EQK6	Gene names	Pla2g10
Domain Architecture
Description	Group 10 secretory phospholipase A2 precursor (EC 3.1.1.4) (Group X secretory phospholipase A2) (Phosphatidylcholine 2-acylhydrolase GX) (GX sPLA2) (sPLA2-X).

PA2GA_MOUSE
θ value	3.87602e-27 (rank : 3)	NC score	0.951113 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	P31482, Q60871	Gene names	Pla2g2a
Domain Architecture
Description	Phospholipase A2, membrane associated precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (Group IIA phospholipase A2) (GIIC sPLA2) (Enhancing factor) (EF).

PA2GE_HUMAN
θ value	3.62785e-25 (rank : 4)	NC score	0.947524 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NZK7	Gene names	PLA2G2E
Domain Architecture
Description	Group IIE secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIIE) (GIIE sPLA2) (sPLA(2)-IIE).

PA2GE_MOUSE
θ value	4.01107e-24 (rank : 5)	NC score	0.944780 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QUL3	Gene names	Pla2g2e
Domain Architecture
Description	Group IIE secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIIE) (GIIE sPLA2) (sPLA(2)-IIE).

PA2GF_MOUSE
θ value	2.59989e-23 (rank : 6)	NC score	0.929056 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QZT4	Gene names	Pla2g2f
Domain Architecture
Description	Group IIF secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIIF) (GIIF sPLA2) (sPLA(2)-IIF).

PA2GD_MOUSE
θ value	3.39556e-23 (rank : 7)	NC score	0.941703 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WVF6, Q3V4B8, Q9JLK0	Gene names	Pla2g2d, Pla2a2, Splash
Domain Architecture
Description	Group IID secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIID) (GIID sPLA2) (PLA2IID) (sPLA(2)-IID) (Secretory-type PLA, stroma-associated homolog).

PA2GF_HUMAN
θ value	7.56453e-23 (rank : 8)	NC score	0.927846 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BZM2, Q5R385, Q8N217, Q9H506	Gene names	PLA2G2F
Domain Architecture
Description	Group IIF secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIIF) (GIIF sPLA2) (sPLA(2)-IIF).

PA2GD_HUMAN
θ value	9.87957e-23 (rank : 9)	NC score	0.940076 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UNK4, Q9UK01	Gene names	PLA2G2D, SPLASH
Domain Architecture
Description	Group IID secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIID) (GIID sPLA2) (PLA2IID) (sPLA(2)-IID) (Secretory-type PLA, stroma-associated homolog).

PA2GA_HUMAN
θ value	8.36355e-22 (rank : 10)	NC score	0.944846 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	P14555, Q6DN24, Q6IBD9, Q9UCD2	Gene names	PLA2G2A, PLA2B, PLA2L, RASF-A
Domain Architecture
Description	Phospholipase A2, membrane associated precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (Group IIA phospholipase A2) (GIIC sPLA2) (Non-pancreatic secretory phospholipase A2) (NPS-PLA2).

PA2G5_MOUSE
θ value	9.24701e-21 (rank : 11)	NC score	0.922108 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	P97391, Q9QZU6	Gene names	Pla2g5
Domain Architecture
Description	Calcium-dependent phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (PLA2-10) (Group V phospholipase A2).

PA2G5_HUMAN
θ value	2.06002e-20 (rank : 12)	NC score	0.920485 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	P39877, Q8N435	Gene names	PLA2G5
Domain Architecture
Description	Calcium-dependent phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (PLA2-10) (Group V phospholipase A2).

PA21B_MOUSE
θ value	2.27762e-19 (rank : 13)	NC score	0.903694 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0Y2, Q9D7E2, Q9D884	Gene names	Pla2g1b, Pla2
Domain Architecture
Description	Phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase) (Group IB phospholipase A2) (PLA2-Ib).

PA2GC_MOUSE
θ value	4.29542e-18 (rank : 14)	NC score	0.928969 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	P48076	Gene names	Pla2g2c
Domain Architecture
Description	Group IIC secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIIC) (GIIC sPLA2) (PLA2-8) (14 kDa phospholipase A2).

PA21B_HUMAN
θ value	2.7842e-17 (rank : 15)	NC score	0.895915 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	P04054, Q3KPI1	Gene names	PLA2G1B, PLA2, PLA2A
Domain Architecture
Description	Phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase) (Group IB phospholipase A2).

OC90_HUMAN
θ value	3.63628e-17 (rank : 16)	NC score	0.786516 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	Q02509	Gene names	OC90, PLA2L
Domain Architecture
Description	Otoconin 90 precursor (Oc90) (Phospholipase A2 homolog).

OC90_MOUSE
θ value	2.35696e-16 (rank : 17)	NC score	0.783753 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	48	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0L3, Q9CZ60, Q9Z225	Gene names	Oc90, Onc-95, Pla2ll
Domain Architecture
Description	Otoconin 90 precursor (Oc90) (Otoconin-95) (Oc95).

LRP8_MOUSE
θ value	0.47712 (rank : 18)	NC score	0.037555 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	385	Shared Neighborhood Hits	18
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

DPF1_MOUSE
θ value	1.06291 (rank : 19)	NC score	0.018383 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	491	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

LRP8_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.037386 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	346	Shared Neighborhood Hits	18
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

CORIN_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.018161 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	453	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

STAB1_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.021543 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	546	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

REQU_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.017515 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	519	Shared Neighborhood Hits	3
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

LRP2_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.032381 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	573	Shared Neighborhood Hits	18
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

ADM1A_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.007482 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	230	Shared Neighborhood Hits	14
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

CORIN_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.017275 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	451	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

KRA51_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.023385 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	288	Shared Neighborhood Hits	19
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LDLR_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.033377 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	375	Shared Neighborhood Hits	18
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.030037 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	617	Shared Neighborhood Hits	18
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

PGBM_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.015232 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	1073	Shared Neighborhood Hits	18
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SSPO_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.022428 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	800	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

STAB1_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.016863 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	566	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

GRN_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.023079 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	268	Shared Neighborhood Hits	16
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

LRP1B_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.029637 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	602	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

PGBM_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.013953 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	1113	Shared Neighborhood Hits	18
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LRP1B_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.029680 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	606	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

Hits sorted by NC score

PA2GX_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.89267e-82 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	O15496, Q6NT23	Gene names	PLA2G10
Domain Architecture
Description	Group 10 secretory phospholipase A2 precursor (EC 3.1.1.4) (Group X secretory phospholipase A2) (Phosphatidylcholine 2-acylhydrolase GX) (GX sPLA2) (sPLA2-X).

PA2GX_MOUSE
NC score	0.994285 (rank : 2)	θ value	1.04338e-64 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	18	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXX3, Q9EQK6	Gene names	Pla2g10
Domain Architecture
Description	Group 10 secretory phospholipase A2 precursor (EC 3.1.1.4) (Group X secretory phospholipase A2) (Phosphatidylcholine 2-acylhydrolase GX) (GX sPLA2) (sPLA2-X).

PA2GA_MOUSE
NC score	0.951113 (rank : 3)	θ value	3.87602e-27 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	P31482, Q60871	Gene names	Pla2g2a
Domain Architecture
Description	Phospholipase A2, membrane associated precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (Group IIA phospholipase A2) (GIIC sPLA2) (Enhancing factor) (EF).

PA2GE_HUMAN
NC score	0.947524 (rank : 4)	θ value	3.62785e-25 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NZK7	Gene names	PLA2G2E
Domain Architecture
Description	Group IIE secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIIE) (GIIE sPLA2) (sPLA(2)-IIE).

PA2GA_HUMAN
NC score	0.944846 (rank : 5)	θ value	8.36355e-22 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	P14555, Q6DN24, Q6IBD9, Q9UCD2	Gene names	PLA2G2A, PLA2B, PLA2L, RASF-A
Domain Architecture
Description	Phospholipase A2, membrane associated precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (Group IIA phospholipase A2) (GIIC sPLA2) (Non-pancreatic secretory phospholipase A2) (NPS-PLA2).

PA2GE_MOUSE
NC score	0.944780 (rank : 6)	θ value	4.01107e-24 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QUL3	Gene names	Pla2g2e
Domain Architecture
Description	Group IIE secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIIE) (GIIE sPLA2) (sPLA(2)-IIE).

PA2GD_MOUSE
NC score	0.941703 (rank : 7)	θ value	3.39556e-23 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WVF6, Q3V4B8, Q9JLK0	Gene names	Pla2g2d, Pla2a2, Splash
Domain Architecture
Description	Group IID secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIID) (GIID sPLA2) (PLA2IID) (sPLA(2)-IID) (Secretory-type PLA, stroma-associated homolog).

PA2GD_HUMAN
NC score	0.940076 (rank : 8)	θ value	9.87957e-23 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UNK4, Q9UK01	Gene names	PLA2G2D, SPLASH
Domain Architecture
Description	Group IID secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIID) (GIID sPLA2) (PLA2IID) (sPLA(2)-IID) (Secretory-type PLA, stroma-associated homolog).

PA2GF_MOUSE
NC score	0.929056 (rank : 9)	θ value	2.59989e-23 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QZT4	Gene names	Pla2g2f
Domain Architecture
Description	Group IIF secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIIF) (GIIF sPLA2) (sPLA(2)-IIF).

PA2GC_MOUSE
NC score	0.928969 (rank : 10)	θ value	4.29542e-18 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	P48076	Gene names	Pla2g2c
Domain Architecture
Description	Group IIC secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIIC) (GIIC sPLA2) (PLA2-8) (14 kDa phospholipase A2).

PA2GF_HUMAN
NC score	0.927846 (rank : 11)	θ value	7.56453e-23 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BZM2, Q5R385, Q8N217, Q9H506	Gene names	PLA2G2F
Domain Architecture
Description	Group IIF secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GIIF) (GIIF sPLA2) (sPLA(2)-IIF).

PA2G5_MOUSE
NC score	0.922108 (rank : 12)	θ value	9.24701e-21 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	P97391, Q9QZU6	Gene names	Pla2g5
Domain Architecture
Description	Calcium-dependent phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (PLA2-10) (Group V phospholipase A2).

PA2G5_HUMAN
NC score	0.920485 (rank : 13)	θ value	2.06002e-20 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	P39877, Q8N435	Gene names	PLA2G5
Domain Architecture
Description	Calcium-dependent phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (PLA2-10) (Group V phospholipase A2).

PA21B_MOUSE
NC score	0.903694 (rank : 14)	θ value	2.27762e-19 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0Y2, Q9D7E2, Q9D884	Gene names	Pla2g1b, Pla2
Domain Architecture
Description	Phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase) (Group IB phospholipase A2) (PLA2-Ib).

PA21B_HUMAN
NC score	0.895915 (rank : 15)	θ value	2.7842e-17 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	P04054, Q3KPI1	Gene names	PLA2G1B, PLA2, PLA2A
Domain Architecture
Description	Phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase) (Group IB phospholipase A2).

OC90_HUMAN
NC score	0.786516 (rank : 16)	θ value	3.63628e-17 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	Q02509	Gene names	OC90, PLA2L
Domain Architecture
Description	Otoconin 90 precursor (Oc90) (Phospholipase A2 homolog).

OC90_MOUSE
NC score	0.783753 (rank : 17)	θ value	2.35696e-16 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	48	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0L3, Q9CZ60, Q9Z225	Gene names	Oc90, Onc-95, Pla2ll
Domain Architecture
Description	Otoconin 90 precursor (Oc90) (Otoconin-95) (Oc95).

LRP8_MOUSE
NC score	0.037555 (rank : 18)	θ value	0.47712 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	385	Shared Neighborhood Hits	18
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_HUMAN
NC score	0.037386 (rank : 19)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	346	Shared Neighborhood Hits	18
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LDLR_HUMAN
NC score	0.033377 (rank : 20)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	375	Shared Neighborhood Hits	18
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP2_HUMAN
NC score	0.032381 (rank : 21)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	573	Shared Neighborhood Hits	18
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP1_HUMAN
NC score	0.030037 (rank : 22)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	617	Shared Neighborhood Hits	18
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP1B_MOUSE
NC score	0.029680 (rank : 23)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	606	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_HUMAN
NC score	0.029637 (rank : 24)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	602	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

KRA51_HUMAN
NC score	0.023385 (rank : 25)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	288	Shared Neighborhood Hits	19
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

GRN_HUMAN
NC score	0.023079 (rank : 26)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	268	Shared Neighborhood Hits	16
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

SSPO_MOUSE
NC score	0.022428 (rank : 27)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	800	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

STAB1_HUMAN
NC score	0.021543 (rank : 28)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	546	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

DPF1_MOUSE
NC score	0.018383 (rank : 29)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	491	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

CORIN_HUMAN
NC score	0.018161 (rank : 30)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	453	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

REQU_MOUSE
NC score	0.017515 (rank : 31)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	519	Shared Neighborhood Hits	3
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

CORIN_MOUSE
NC score	0.017275 (rank : 32)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	451	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

STAB1_MOUSE
NC score	0.016863 (rank : 33)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	566	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

PGBM_MOUSE
NC score	0.015232 (rank : 34)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	1073	Shared Neighborhood Hits	18
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_HUMAN
NC score	0.013953 (rank : 35)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	1113	Shared Neighborhood Hits	18
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ADM1A_MOUSE
NC score	0.007482 (rank : 36)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	230	Shared Neighborhood Hits	14
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).