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Network neighborhood for query Sequence : NICA_HUMAN

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NICA_HUMAN
SwissProt Accessions	Q92542, Q86VV5	Gene names	NCSTN, KIAA0253
Domain Architecture
Description	Nicastrin precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NICA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q92542, Q86VV5	Gene names	NCSTN, KIAA0253
Domain Architecture
Description	Nicastrin precursor.

NICA_MOUSE
θ value	0 (rank : 2)	NC score	0.997421 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P57716, Q8VE20	Gene names	Ncstn
Domain Architecture
Description	Nicastrin precursor.

DEPD5_HUMAN
θ value	1.81305 (rank : 3)	NC score	0.031140 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	O75140, Q5K3V5, Q5THY9, Q5THZ0, Q5THZ1, Q5THZ3, Q68DR1, Q6MZX3, Q6PEZ1, Q9UGV8, Q9UH13	Gene names	DEPDC5, KIAA0645
Domain Architecture
Description	DEP domain-containing protein 5.

GMEB2_MOUSE
θ value	1.81305 (rank : 4)	NC score	0.050318 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

GRAH_HUMAN
θ value	1.81305 (rank : 5)	NC score	0.008019 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

STIP1_MOUSE
θ value	2.36792 (rank : 6)	NC score	0.036300 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

LIRA2_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.009772 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N149, O75020	Gene names	LILRA2, ILT1, LIR7
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily A member 2 precursor (Leukocyte immunoglobulin-like receptor 7) (LIR-7) (Immunoglobulin- like transcript 1) (ILT-1) (CD85h antigen).

TENA_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.005663 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	596	Shared Neighborhood Hits	2
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TR2_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.013407 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

CSPG4_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.021032 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

STIP1_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.022718 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	P31948	Gene names	STIP1
Domain Architecture
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY- REN-11 antigen).

GMEB2_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.036336 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

SMG1_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.011720 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	231	Shared Neighborhood Hits	2
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

TTC7B_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.013298 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q86TV6, Q86U24, Q86VT3	Gene names	TTC7B, TTC7L1
Domain Architecture
Description	Tetratricopeptide repeat protein 7B (Tetratricopeptide repeat protein 7-like-1).

Hits sorted by NC score

NICA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q92542, Q86VV5	Gene names	NCSTN, KIAA0253
Domain Architecture
Description	Nicastrin precursor.

NICA_MOUSE
NC score	0.997421 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P57716, Q8VE20	Gene names	Ncstn
Domain Architecture
Description	Nicastrin precursor.

GMEB2_MOUSE
NC score	0.050318 (rank : 3)	θ value	1.81305 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

GMEB2_HUMAN
NC score	0.036336 (rank : 4)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

STIP1_MOUSE
NC score	0.036300 (rank : 5)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

DEPD5_HUMAN
NC score	0.031140 (rank : 6)	θ value	1.81305 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	O75140, Q5K3V5, Q5THY9, Q5THZ0, Q5THZ1, Q5THZ3, Q68DR1, Q6MZX3, Q6PEZ1, Q9UGV8, Q9UH13	Gene names	DEPDC5, KIAA0645
Domain Architecture
Description	DEP domain-containing protein 5.

STIP1_HUMAN
NC score	0.022718 (rank : 7)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	P31948	Gene names	STIP1
Domain Architecture
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY- REN-11 antigen).

CSPG4_MOUSE
NC score	0.021032 (rank : 8)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

TR2_HUMAN
NC score	0.013407 (rank : 9)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

TTC7B_HUMAN
NC score	0.013298 (rank : 10)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q86TV6, Q86U24, Q86VT3	Gene names	TTC7B, TTC7L1
Domain Architecture
Description	Tetratricopeptide repeat protein 7B (Tetratricopeptide repeat protein 7-like-1).

SMG1_HUMAN
NC score	0.011720 (rank : 11)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	231	Shared Neighborhood Hits	2
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

LIRA2_HUMAN
NC score	0.009772 (rank : 12)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N149, O75020	Gene names	LILRA2, ILT1, LIR7
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily A member 2 precursor (Leukocyte immunoglobulin-like receptor 7) (LIR-7) (Immunoglobulin- like transcript 1) (ILT-1) (CD85h antigen).

GRAH_HUMAN
NC score	0.008019 (rank : 13)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

TENA_MOUSE
NC score	0.005663 (rank : 14)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	596	Shared Neighborhood Hits	2
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).