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Network neighborhood for query Sequence : NBL1_HUMAN

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NBL1_HUMAN
SwissProt Accessions	P41271, Q96L68	Gene names	NBL1, DAN
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NBL1_HUMAN
θ value	2.92676e-75 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	P41271, Q96L68	Gene names	NBL1, DAN
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

NBL1_MOUSE
θ value	1.66191e-70 (rank : 2)	NC score	0.992125 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	Q61477	Gene names	Nbl1, Dan, Dana
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

GREM2_MOUSE
θ value	1.42992e-13 (rank : 3)	NC score	0.726086 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	O88273	Gene names	Grem2, Cktsf1b2, Prdc
Domain Architecture	No domain graphic available
Description	Gremlin-2 precursor (Cysteine knot superfamily 1, BMP antagonist 2) (Protein related to DAN and cerberus).

GREM2_HUMAN
θ value	1.58096e-12 (rank : 4)	NC score	0.715106 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H772, Q86UD9	Gene names	GREM2, CKTSF1B2, DAND3, PRDC
Domain Architecture	No domain graphic available
Description	Gremlin-2 precursor (Cysteine knot superfamily 1, BMP antagonist 2) (Protein related to DAN and cerberus).

GREM1_HUMAN
θ value	9.59137e-10 (rank : 5)	NC score	0.684821 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	O60565, Q52LV3, Q8N914, Q8N936	Gene names	GREM1, CKTSF1B1, DAND2, DRM, PIG2
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Increased in high glucose protein 2) (IHG-2) (Down-regulated in Mos- transformed cells protein) (Proliferation-inducing gene 2 protein).

GREM1_MOUSE
θ value	9.59137e-10 (rank : 6)	NC score	0.684936 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	O70326	Gene names	Grem1, Cktsf1b1, Drm
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Down-regulated in Mos-transformed cells protein).

CER1_HUMAN
θ value	8.40245e-06 (rank : 7)	NC score	0.513123 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	O95813, Q6ISJ1, Q6ISJ6, Q6ISQ2, Q6ISS1	Gene names	CER1
Domain Architecture	No domain graphic available
Description	Cerberus precursor (Cerberus-related protein).

CER1_MOUSE
θ value	0.00228821 (rank : 8)	NC score	0.449257 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	O55233, O35213	Gene names	Cer1, Cerl, Cerr1
Domain Architecture	No domain graphic available
Description	Cerberus precursor (Cerberus-related protein) (Cerberus-like protein) (Cer-l).

A2BP1_HUMAN
θ value	0.163984 (rank : 9)	NC score	0.049292 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	229	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWB1, Q9NS20	Gene names	A2BP1, A2BP
Domain Architecture
Description	Ataxin-2-binding protein 1.

TCGAP_HUMAN
θ value	0.163984 (rank : 10)	NC score	0.041675 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	872	Shared Neighborhood Hits	5
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

C16L2_MOUSE
θ value	0.21417 (rank : 11)	NC score	0.086497 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6W7	Gene names	Cd164l2
Domain Architecture	No domain graphic available
Description	CD164 sialomucin-like 2 protein precursor.

MUC5B_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.032387 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	1020	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

EMIL2_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.025320 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	573	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

HIPK2_MOUSE
θ value	2.36792 (rank : 14)	NC score	0.013831 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	871	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZR5, O88905, Q99P45, Q99P46, Q9D2E6, Q9D474, Q9EQL2, Q9QZR4	Gene names	Hipk2, Nbak1, Stank
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body- associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase).

APBA2_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.019108 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	220	Shared Neighborhood Hits	2
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

FGD2_MOUSE
θ value	3.0926 (rank : 16)	NC score	0.017744 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

HIPK2_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.013122 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	845	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2X6, Q75MR7, Q8WWI4, Q9H2Y1	Gene names	HIPK2
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (hHIPk2).

CD008_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.030359 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	330	Shared Neighborhood Hits	2
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

A2BP1_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.037590 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJ43, Q9JJB5	Gene names	A2bp1, A2bp
Domain Architecture
Description	Ataxin-2-binding protein 1.

CUTL2_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.016690 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	906	Shared Neighborhood Hits	6
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

EMIL2_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.028661 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	485	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

ZN358_HUMAN
θ value	8.99809 (rank : 22)	NC score	-0.000925 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	840	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.

MUC2_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.054057 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	906	Shared Neighborhood Hits	11
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

Hits sorted by NC score

NBL1_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.92676e-75 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	P41271, Q96L68	Gene names	NBL1, DAN
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

NBL1_MOUSE
NC score	0.992125 (rank : 2)	θ value	1.66191e-70 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	Q61477	Gene names	Nbl1, Dan, Dana
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

GREM2_MOUSE
NC score	0.726086 (rank : 3)	θ value	1.42992e-13 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	O88273	Gene names	Grem2, Cktsf1b2, Prdc
Domain Architecture	No domain graphic available
Description	Gremlin-2 precursor (Cysteine knot superfamily 1, BMP antagonist 2) (Protein related to DAN and cerberus).

GREM2_HUMAN
NC score	0.715106 (rank : 4)	θ value	1.58096e-12 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H772, Q86UD9	Gene names	GREM2, CKTSF1B2, DAND3, PRDC
Domain Architecture	No domain graphic available
Description	Gremlin-2 precursor (Cysteine knot superfamily 1, BMP antagonist 2) (Protein related to DAN and cerberus).

GREM1_MOUSE
NC score	0.684936 (rank : 5)	θ value	9.59137e-10 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	O70326	Gene names	Grem1, Cktsf1b1, Drm
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Down-regulated in Mos-transformed cells protein).

GREM1_HUMAN
NC score	0.684821 (rank : 6)	θ value	9.59137e-10 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	O60565, Q52LV3, Q8N914, Q8N936	Gene names	GREM1, CKTSF1B1, DAND2, DRM, PIG2
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Increased in high glucose protein 2) (IHG-2) (Down-regulated in Mos- transformed cells protein) (Proliferation-inducing gene 2 protein).

CER1_HUMAN
NC score	0.513123 (rank : 7)	θ value	8.40245e-06 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	O95813, Q6ISJ1, Q6ISJ6, Q6ISQ2, Q6ISS1	Gene names	CER1
Domain Architecture	No domain graphic available
Description	Cerberus precursor (Cerberus-related protein).

CER1_MOUSE
NC score	0.449257 (rank : 8)	θ value	0.00228821 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	O55233, O35213	Gene names	Cer1, Cerl, Cerr1
Domain Architecture	No domain graphic available
Description	Cerberus precursor (Cerberus-related protein) (Cerberus-like protein) (Cer-l).

C16L2_MOUSE
NC score	0.086497 (rank : 9)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6W7	Gene names	Cd164l2
Domain Architecture	No domain graphic available
Description	CD164 sialomucin-like 2 protein precursor.

MUC2_HUMAN
NC score	0.054057 (rank : 10)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	906	Shared Neighborhood Hits	11
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

A2BP1_HUMAN
NC score	0.049292 (rank : 11)	θ value	0.163984 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	229	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWB1, Q9NS20	Gene names	A2BP1, A2BP
Domain Architecture
Description	Ataxin-2-binding protein 1.

TCGAP_HUMAN
NC score	0.041675 (rank : 12)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	872	Shared Neighborhood Hits	5
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

A2BP1_MOUSE
NC score	0.037590 (rank : 13)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJ43, Q9JJB5	Gene names	A2bp1, A2bp
Domain Architecture
Description	Ataxin-2-binding protein 1.

MUC5B_HUMAN
NC score	0.032387 (rank : 14)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	1020	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CD008_HUMAN
NC score	0.030359 (rank : 15)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	330	Shared Neighborhood Hits	2
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

EMIL2_MOUSE
NC score	0.028661 (rank : 16)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	485	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

EMIL2_HUMAN
NC score	0.025320 (rank : 17)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	573	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

APBA2_HUMAN
NC score	0.019108 (rank : 18)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	220	Shared Neighborhood Hits	2
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

FGD2_MOUSE
NC score	0.017744 (rank : 19)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

CUTL2_HUMAN
NC score	0.016690 (rank : 20)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	906	Shared Neighborhood Hits	6
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

HIPK2_MOUSE
NC score	0.013831 (rank : 21)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	871	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZR5, O88905, Q99P45, Q99P46, Q9D2E6, Q9D474, Q9EQL2, Q9QZR4	Gene names	Hipk2, Nbak1, Stank
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body- associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase).

HIPK2_HUMAN
NC score	0.013122 (rank : 22)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	845	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2X6, Q75MR7, Q8WWI4, Q9H2Y1	Gene names	HIPK2
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (hHIPk2).

ZN358_HUMAN
NC score	-0.000925 (rank : 23)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	840	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.