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Network neighborhood for query Sequence : GREM1_MOUSE

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GREM1_MOUSE
SwissProt Accessions	O70326	Gene names	Grem1, Cktsf1b1, Drm
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Down-regulated in Mos-transformed cells protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GREM1_HUMAN
θ value	9.07703e-85 (rank : 1)	NC score	0.999407 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O60565, Q52LV3, Q8N914, Q8N936	Gene names	GREM1, CKTSF1B1, DAND2, DRM, PIG2
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Increased in high glucose protein 2) (IHG-2) (Down-regulated in Mos- transformed cells protein) (Proliferation-inducing gene 2 protein).

GREM1_MOUSE
θ value	1.18549e-84 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O70326	Gene names	Grem1, Cktsf1b1, Drm
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Down-regulated in Mos-transformed cells protein).

GREM2_HUMAN
θ value	6.7944e-48 (rank : 3)	NC score	0.972606 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H772, Q86UD9	Gene names	GREM2, CKTSF1B2, DAND3, PRDC
Domain Architecture	No domain graphic available
Description	Gremlin-2 precursor (Cysteine knot superfamily 1, BMP antagonist 2) (Protein related to DAN and cerberus).

GREM2_MOUSE
θ value	2.18568e-46 (rank : 4)	NC score	0.972037 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	O88273	Gene names	Grem2, Cktsf1b2, Prdc
Domain Architecture	No domain graphic available
Description	Gremlin-2 precursor (Cysteine knot superfamily 1, BMP antagonist 2) (Protein related to DAN and cerberus).

CER1_HUMAN
θ value	2.69671e-12 (rank : 5)	NC score	0.665923 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	O95813, Q6ISJ1, Q6ISJ6, Q6ISQ2, Q6ISS1	Gene names	CER1
Domain Architecture	No domain graphic available
Description	Cerberus precursor (Cerberus-related protein).

CER1_MOUSE
θ value	4.30538e-10 (rank : 6)	NC score	0.625995 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	O55233, O35213	Gene names	Cer1, Cerl, Cerr1
Domain Architecture	No domain graphic available
Description	Cerberus precursor (Cerberus-related protein) (Cerberus-like protein) (Cer-l).

NBL1_MOUSE
θ value	4.30538e-10 (rank : 7)	NC score	0.693192 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q61477	Gene names	Nbl1, Dan, Dana
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

NBL1_HUMAN
θ value	9.59137e-10 (rank : 8)	NC score	0.684936 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	P41271, Q96L68	Gene names	NBL1, DAN
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

MUC2_HUMAN
θ value	0.000158464 (rank : 9)	NC score	0.113342 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PKHA6_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.013271 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	556	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RBP2_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.012507 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	249	Shared Neighborhood Hits	4
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

LAD1_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.009312 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	441	Shared Neighborhood Hits	2
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

Hits sorted by NC score

GREM1_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.18549e-84 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O70326	Gene names	Grem1, Cktsf1b1, Drm
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Down-regulated in Mos-transformed cells protein).

GREM1_HUMAN
NC score	0.999407 (rank : 2)	θ value	9.07703e-85 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O60565, Q52LV3, Q8N914, Q8N936	Gene names	GREM1, CKTSF1B1, DAND2, DRM, PIG2
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Increased in high glucose protein 2) (IHG-2) (Down-regulated in Mos- transformed cells protein) (Proliferation-inducing gene 2 protein).

GREM2_HUMAN
NC score	0.972606 (rank : 3)	θ value	6.7944e-48 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H772, Q86UD9	Gene names	GREM2, CKTSF1B2, DAND3, PRDC
Domain Architecture	No domain graphic available
Description	Gremlin-2 precursor (Cysteine knot superfamily 1, BMP antagonist 2) (Protein related to DAN and cerberus).

GREM2_MOUSE
NC score	0.972037 (rank : 4)	θ value	2.18568e-46 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	O88273	Gene names	Grem2, Cktsf1b2, Prdc
Domain Architecture	No domain graphic available
Description	Gremlin-2 precursor (Cysteine knot superfamily 1, BMP antagonist 2) (Protein related to DAN and cerberus).

NBL1_MOUSE
NC score	0.693192 (rank : 5)	θ value	4.30538e-10 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q61477	Gene names	Nbl1, Dan, Dana
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

NBL1_HUMAN
NC score	0.684936 (rank : 6)	θ value	9.59137e-10 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	P41271, Q96L68	Gene names	NBL1, DAN
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

CER1_HUMAN
NC score	0.665923 (rank : 7)	θ value	2.69671e-12 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	O95813, Q6ISJ1, Q6ISJ6, Q6ISQ2, Q6ISS1	Gene names	CER1
Domain Architecture	No domain graphic available
Description	Cerberus precursor (Cerberus-related protein).

CER1_MOUSE
NC score	0.625995 (rank : 8)	θ value	4.30538e-10 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	O55233, O35213	Gene names	Cer1, Cerl, Cerr1
Domain Architecture	No domain graphic available
Description	Cerberus precursor (Cerberus-related protein) (Cerberus-like protein) (Cer-l).

MUC2_HUMAN
NC score	0.113342 (rank : 9)	θ value	0.000158464 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PKHA6_HUMAN
NC score	0.013271 (rank : 10)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	556	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RBP2_HUMAN
NC score	0.012507 (rank : 11)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	249	Shared Neighborhood Hits	4
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

LAD1_HUMAN
NC score	0.009312 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	441	Shared Neighborhood Hits	2
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).