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Network neighborhood for query Sequence : MTHR_HUMAN

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MTHR_HUMAN
SwissProt Accessions	P42898, Q7Z6M6, Q9UQR2	Gene names	MTHFR
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MTHR_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	P42898, Q7Z6M6, Q9UQR2	Gene names	MTHFR
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).

MTHR_MOUSE
θ value	0 (rank : 2)	NC score	0.998531 (rank : 2)
Query Neighborhood Hits	7	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WU20	Gene names	Mthfr
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).

K0146_MOUSE
θ value	1.38821 (rank : 3)	NC score	0.037972 (rank : 4)
Query Neighborhood Hits	7	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGX7, Q3TCD0, Q5U457, Q6A0B6, Q6IS60, Q811E1, Q8BWD6, Q8R305	Gene names	Kiaa0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

CCAR1_HUMAN
θ value	2.36792 (rank : 4)	NC score	0.033171 (rank : 5)
Query Neighborhood Hits	7	Target Neighborhood Hits	444	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

2ACC_HUMAN
θ value	3.0926 (rank : 5)	NC score	0.040368 (rank : 3)
Query Neighborhood Hits	7	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5P8	Gene names	PPP2R3B, PPP2R3L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 48 kDa regulatory subunit B (PP2A, subunit B, PR48 isoform).

IL6RB_MOUSE
θ value	6.88961 (rank : 6)	NC score	0.010916 (rank : 6)
Query Neighborhood Hits	7	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

MYLK_HUMAN
θ value	6.88961 (rank : 7)	NC score	0.001499 (rank : 7)
Query Neighborhood Hits	7	Target Neighborhood Hits	1328	Shared Neighborhood Hits	3
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

Hits sorted by NC score

MTHR_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	P42898, Q7Z6M6, Q9UQR2	Gene names	MTHFR
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).

MTHR_MOUSE
NC score	0.998531 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	7	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WU20	Gene names	Mthfr
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).

2ACC_HUMAN
NC score	0.040368 (rank : 3)	θ value	3.0926 (rank : 5)
Query Neighborhood Hits	7	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5P8	Gene names	PPP2R3B, PPP2R3L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 48 kDa regulatory subunit B (PP2A, subunit B, PR48 isoform).

K0146_MOUSE
NC score	0.037972 (rank : 4)	θ value	1.38821 (rank : 3)
Query Neighborhood Hits	7	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGX7, Q3TCD0, Q5U457, Q6A0B6, Q6IS60, Q811E1, Q8BWD6, Q8R305	Gene names	Kiaa0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

CCAR1_HUMAN
NC score	0.033171 (rank : 5)	θ value	2.36792 (rank : 4)
Query Neighborhood Hits	7	Target Neighborhood Hits	444	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

IL6RB_MOUSE
NC score	0.010916 (rank : 6)	θ value	6.88961 (rank : 6)
Query Neighborhood Hits	7	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

MYLK_HUMAN
NC score	0.001499 (rank : 7)	θ value	6.88961 (rank : 7)
Query Neighborhood Hits	7	Target Neighborhood Hits	1328	Shared Neighborhood Hits	3
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).