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Network neighborhood for query Sequence : 2ACC_HUMAN

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2ACC_HUMAN
SwissProt Accessions	Q9Y5P8	Gene names	PPP2R3B, PPP2R3L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 48 kDa regulatory subunit B (PP2A, subunit B, PR48 isoform).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

2ACC_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5P8	Gene names	PPP2R3B, PPP2R3L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 48 kDa regulatory subunit B (PP2A, subunit B, PR48 isoform).

2ACA_HUMAN
θ value	1.56551e-161 (rank : 2)	NC score	0.942442 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q06190, Q06189, Q9NPQ5	Gene names	PPP2R3A, PPP2R3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B (PP2A, subunit B, B''-PR72/PR130) (PP2A, subunit B, B72/B130 isoforms) (PP2A, subunit B, PR72/PR130 isoforms) (PP2A, subunit B, R3 isoform).

2A5R_MOUSE
θ value	2.12077e-150 (rank : 3)	NC score	0.986506 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z176	Gene names	Ppp2r3a, Ppp2r6
Domain Architecture	No domain graphic available
Description	Protein phosphatase 2A, 59 kDa regulatory subunit B (PP2A PR59) (PP2A B''-PR59).

DGKB_HUMAN
θ value	0.21417 (rank : 4)	NC score	0.045437 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	238	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

KS6A5_HUMAN
θ value	0.365318 (rank : 5)	NC score	0.007819 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	855	Shared Neighborhood Hits	3
SwissProt Accessions	O75582, O95316, Q96AF7	Gene names	RPS6KA5, MSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL).

KS6A5_MOUSE
θ value	1.06291 (rank : 6)	NC score	0.007539 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	854	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C050, Q8CI92	Gene names	Rps6ka5, Msk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK).

EFHB_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.035121 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	125	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N7U6, Q6ZWK9, Q8IV58, Q96LQ6	Gene names	EFHB
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

GUC1C_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.026700 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	148	Shared Neighborhood Hits	9
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

MTHR_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.040368 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P42898, Q7Z6M6, Q9UQR2	Gene names	MTHFR
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).

MTHR_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.040357 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WU20	Gene names	Mthfr
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).

EEA1_MOUSE
θ value	5.27518 (rank : 11)	NC score	0.005354 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	1637	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

NCS1_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.018186 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	P62166, P36610, Q9UK26	Gene names	FREQ, FLUP, NCS1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein).

NCS1_MOUSE
θ value	5.27518 (rank : 13)	NC score	0.018186 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BNY6	Gene names	Freq, Ncs1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog).

CALB2_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.021098 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

CALB2_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.020995 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

CLMN_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.007890 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

COIA1_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.005995 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	481	Shared Neighborhood Hits	2
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

K0460_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.020916 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

K0460_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.020672 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	374	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

NDST4_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.007398 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

EFCB1_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.018743 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	126	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D3N2, Q8BSW3, Q8C982, Q8CAI0, Q9D527, Q9D5E7	Gene names	Efcab1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

Hits sorted by NC score

2ACC_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5P8	Gene names	PPP2R3B, PPP2R3L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 48 kDa regulatory subunit B (PP2A, subunit B, PR48 isoform).

2A5R_MOUSE
NC score	0.986506 (rank : 2)	θ value	2.12077e-150 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z176	Gene names	Ppp2r3a, Ppp2r6
Domain Architecture	No domain graphic available
Description	Protein phosphatase 2A, 59 kDa regulatory subunit B (PP2A PR59) (PP2A B''-PR59).

2ACA_HUMAN
NC score	0.942442 (rank : 3)	θ value	1.56551e-161 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q06190, Q06189, Q9NPQ5	Gene names	PPP2R3A, PPP2R3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B (PP2A, subunit B, B''-PR72/PR130) (PP2A, subunit B, B72/B130 isoforms) (PP2A, subunit B, PR72/PR130 isoforms) (PP2A, subunit B, R3 isoform).

DGKB_HUMAN
NC score	0.045437 (rank : 4)	θ value	0.21417 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	238	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

MTHR_HUMAN
NC score	0.040368 (rank : 5)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P42898, Q7Z6M6, Q9UQR2	Gene names	MTHFR
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).

MTHR_MOUSE
NC score	0.040357 (rank : 6)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WU20	Gene names	Mthfr
Domain Architecture
Description	Methylenetetrahydrofolate reductase (EC 1.5.1.20).

EFHB_HUMAN
NC score	0.035121 (rank : 7)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	125	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N7U6, Q6ZWK9, Q8IV58, Q96LQ6	Gene names	EFHB
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

GUC1C_HUMAN
NC score	0.026700 (rank : 8)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	148	Shared Neighborhood Hits	9
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

CALB2_HUMAN
NC score	0.021098 (rank : 9)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

CALB2_MOUSE
NC score	0.020995 (rank : 10)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

K0460_HUMAN
NC score	0.020916 (rank : 11)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

K0460_MOUSE
NC score	0.020672 (rank : 12)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	374	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

EFCB1_MOUSE
NC score	0.018743 (rank : 13)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	126	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D3N2, Q8BSW3, Q8C982, Q8CAI0, Q9D527, Q9D5E7	Gene names	Efcab1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

NCS1_HUMAN
NC score	0.018186 (rank : 14)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	P62166, P36610, Q9UK26	Gene names	FREQ, FLUP, NCS1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein).

NCS1_MOUSE
NC score	0.018186 (rank : 15)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BNY6	Gene names	Freq, Ncs1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog).

CLMN_MOUSE
NC score	0.007890 (rank : 16)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

KS6A5_HUMAN
NC score	0.007819 (rank : 17)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	855	Shared Neighborhood Hits	3
SwissProt Accessions	O75582, O95316, Q96AF7	Gene names	RPS6KA5, MSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL).

KS6A5_MOUSE
NC score	0.007539 (rank : 18)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	854	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C050, Q8CI92	Gene names	Rps6ka5, Msk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK).

NDST4_HUMAN
NC score	0.007398 (rank : 19)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

COIA1_MOUSE
NC score	0.005995 (rank : 20)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	481	Shared Neighborhood Hits	2
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

EEA1_MOUSE
NC score	0.005354 (rank : 21)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	1637	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.