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Network neighborhood for query Sequence : MSLN_MOUSE

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MSLN_MOUSE
SwissProt Accessions	Q61468	Gene names	Msln, Mes, Mpf
Domain Architecture	No domain graphic available
Description	Mesothelin precursor (Pre-pro-megakaryocyte potentiating factor) [Contains: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MSLN_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q61468	Gene names	Msln, Mes, Mpf
Domain Architecture	No domain graphic available
Description	Mesothelin precursor (Pre-pro-megakaryocyte potentiating factor) [Contains: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form].

MSLN_HUMAN
θ value	5.9214e-177 (rank : 2)	NC score	0.973987 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q13421, Q14859, Q4VQD5, Q96GR6, Q96KJ5, Q9BR17, Q9BTR2, Q9UK57	Gene names	MSLN, MPF
Domain Architecture
Description	Mesothelin precursor (Pre-pro-megakaryocyte potentiating factor) (CAK1 antigen) [Contains: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form].

OTOAN_MOUSE
θ value	8.97725e-08 (rank : 3)	NC score	0.333416 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K561	Gene names	Otoa
Domain Architecture	No domain graphic available
Description	Otoancorin precursor.

OTOAN_HUMAN
θ value	2.21117e-06 (rank : 4)	NC score	0.250585 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q7RTW8, Q8NA86, Q96M76	Gene names	OTOA
Domain Architecture	No domain graphic available
Description	Otoancorin precursor.

IFRD1_HUMAN
θ value	0.47712 (rank : 5)	NC score	0.071775 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O00458, O75234, Q5U013, Q9BVE4	Gene names	IFRD1
Domain Architecture
Description	Interferon-related developmental regulator 1 (Nerve growth factor- inducible protein PC4).

IFRD1_MOUSE
θ value	0.62314 (rank : 6)	NC score	0.070267 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P19182, P21835, P70228	Gene names	Ifrd1, Tis7
Domain Architecture
Description	Interferon-related developmental regulator 1 (Nerve growth factor- inducible protein PC4) (TPA-induced sequence 7) (TIS7 protein).

KPCD3_MOUSE
θ value	1.06291 (rank : 7)	NC score	0.008461 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	901	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

CIA30_HUMAN
θ value	1.38821 (rank : 8)	NC score	0.046282 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y375, Q9BVZ5	Gene names	NDUFAF1, CIA30
Domain Architecture	No domain graphic available
Description	Complex I intermediate-associated protein 30, mitochondrial precursor (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1).

KPCD3_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.007628 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	895	Shared Neighborhood Hits	3
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

EDEM2_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.023793 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BV94, Q6IA89, Q6UWZ4, Q9H4U0, Q9H886, Q9NTL9, Q9NVE6	Gene names	EDEM2, C20orf31, C20orf49
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 2 precursor.

RXFP2_HUMAN
θ value	8.99809 (rank : 11)	NC score	0.003674 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	736	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

Hits sorted by NC score

MSLN_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q61468	Gene names	Msln, Mes, Mpf
Domain Architecture	No domain graphic available
Description	Mesothelin precursor (Pre-pro-megakaryocyte potentiating factor) [Contains: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form].

MSLN_HUMAN
NC score	0.973987 (rank : 2)	θ value	5.9214e-177 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q13421, Q14859, Q4VQD5, Q96GR6, Q96KJ5, Q9BR17, Q9BTR2, Q9UK57	Gene names	MSLN, MPF
Domain Architecture
Description	Mesothelin precursor (Pre-pro-megakaryocyte potentiating factor) (CAK1 antigen) [Contains: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form].

OTOAN_MOUSE
NC score	0.333416 (rank : 3)	θ value	8.97725e-08 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K561	Gene names	Otoa
Domain Architecture	No domain graphic available
Description	Otoancorin precursor.

OTOAN_HUMAN
NC score	0.250585 (rank : 4)	θ value	2.21117e-06 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q7RTW8, Q8NA86, Q96M76	Gene names	OTOA
Domain Architecture	No domain graphic available
Description	Otoancorin precursor.

IFRD1_HUMAN
NC score	0.071775 (rank : 5)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O00458, O75234, Q5U013, Q9BVE4	Gene names	IFRD1
Domain Architecture
Description	Interferon-related developmental regulator 1 (Nerve growth factor- inducible protein PC4).

IFRD1_MOUSE
NC score	0.070267 (rank : 6)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P19182, P21835, P70228	Gene names	Ifrd1, Tis7
Domain Architecture
Description	Interferon-related developmental regulator 1 (Nerve growth factor- inducible protein PC4) (TPA-induced sequence 7) (TIS7 protein).

CIA30_HUMAN
NC score	0.046282 (rank : 7)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y375, Q9BVZ5	Gene names	NDUFAF1, CIA30
Domain Architecture	No domain graphic available
Description	Complex I intermediate-associated protein 30, mitochondrial precursor (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1).

EDEM2_HUMAN
NC score	0.023793 (rank : 8)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BV94, Q6IA89, Q6UWZ4, Q9H4U0, Q9H886, Q9NTL9, Q9NVE6	Gene names	EDEM2, C20orf31, C20orf49
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 2 precursor.

KPCD3_MOUSE
NC score	0.008461 (rank : 9)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	901	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

KPCD3_HUMAN
NC score	0.007628 (rank : 10)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	895	Shared Neighborhood Hits	3
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

RXFP2_HUMAN
NC score	0.003674 (rank : 11)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	736	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).