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Network neighborhood for query Sequence : LITAF_HUMAN

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LITAF_HUMAN
SwissProt Accessions	Q99732, Q9C0L6	Gene names	LITAF, PIG7, SIMPLE
Domain Architecture	No domain graphic available
Description	Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LPS- induced TNF-alpha factor) (p53-induced protein 7) (Small integral membrane protein of lysosome/late endosome).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LITAF_HUMAN
θ value	8.83269e-64 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q99732, Q9C0L6	Gene names	LITAF, PIG7, SIMPLE
Domain Architecture	No domain graphic available
Description	Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LPS- induced TNF-alpha factor) (p53-induced protein 7) (Small integral membrane protein of lysosome/late endosome).

LITAF_MOUSE
θ value	8.26713e-62 (rank : 2)	NC score	0.994194 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLJ0, Q9EQI0	Gene names	Litaf, N4wbp3, Tbx1
Domain Architecture	No domain graphic available
Description	Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (LITAF-like protein) (NEDD4 WW domain-binding protein 3) (Estrogen-enhanced transcript protein) (mEET).

JIP3_HUMAN
θ value	3.0926 (rank : 3)	NC score	0.020517 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	1039	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

BCAR1_HUMAN
θ value	4.03905 (rank : 4)	NC score	0.021458 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	554	Shared Neighborhood Hits	4
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CRBB1_MOUSE
θ value	5.27518 (rank : 5)	NC score	0.015156 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WVJ5	Gene names	Crybb1
Domain Architecture	No domain graphic available
Description	Beta crystallin B1 [Contains: Beta crystallin B1B].

SPRR3_MOUSE
θ value	5.27518 (rank : 6)	NC score	0.028812 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

SPT5H_MOUSE
θ value	5.27518 (rank : 7)	NC score	0.038034 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	437	Shared Neighborhood Hits	4
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

TMG4_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.026870 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

CT043_MOUSE
θ value	6.88961 (rank : 9)	NC score	0.027694 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q99K95, Q543D3, Q80X88, Q9CV27	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf43 homolog.

SPT5H_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.036763 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	436	Shared Neighborhood Hits	4
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

TXNIP_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.017331 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H3M7, Q16226, Q6PML0, Q9BXG9	Gene names	TXNIP, VDUP1
Domain Architecture	No domain graphic available
Description	Thioredoxin-interacting protein (Vitamin D3 up-regulated protein 1) (Thioredoxin-binding protein 2).

ARSI_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.012767 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q5FYB1	Gene names	ARSI
Domain Architecture	No domain graphic available
Description	Arylsulfatase I precursor (EC 3.1.6.-) (ASI).

PF21B_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.022561 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.022184 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	278	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

Hits sorted by NC score

LITAF_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.83269e-64 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q99732, Q9C0L6	Gene names	LITAF, PIG7, SIMPLE
Domain Architecture	No domain graphic available
Description	Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LPS- induced TNF-alpha factor) (p53-induced protein 7) (Small integral membrane protein of lysosome/late endosome).

LITAF_MOUSE
NC score	0.994194 (rank : 2)	θ value	8.26713e-62 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLJ0, Q9EQI0	Gene names	Litaf, N4wbp3, Tbx1
Domain Architecture	No domain graphic available
Description	Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (LITAF-like protein) (NEDD4 WW domain-binding protein 3) (Estrogen-enhanced transcript protein) (mEET).

SPT5H_MOUSE
NC score	0.038034 (rank : 3)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	437	Shared Neighborhood Hits	4
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SPT5H_HUMAN
NC score	0.036763 (rank : 4)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	436	Shared Neighborhood Hits	4
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPRR3_MOUSE
NC score	0.028812 (rank : 5)	θ value	5.27518 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

CT043_MOUSE
NC score	0.027694 (rank : 6)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q99K95, Q543D3, Q80X88, Q9CV27	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf43 homolog.

TMG4_HUMAN
NC score	0.026870 (rank : 7)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

PF21B_HUMAN
NC score	0.022561 (rank : 8)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
NC score	0.022184 (rank : 9)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	278	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

BCAR1_HUMAN
NC score	0.021458 (rank : 10)	θ value	4.03905 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	554	Shared Neighborhood Hits	4
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

JIP3_HUMAN
NC score	0.020517 (rank : 11)	θ value	3.0926 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	1039	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

TXNIP_HUMAN
NC score	0.017331 (rank : 12)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H3M7, Q16226, Q6PML0, Q9BXG9	Gene names	TXNIP, VDUP1
Domain Architecture	No domain graphic available
Description	Thioredoxin-interacting protein (Vitamin D3 up-regulated protein 1) (Thioredoxin-binding protein 2).

CRBB1_MOUSE
NC score	0.015156 (rank : 13)	θ value	5.27518 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WVJ5	Gene names	Crybb1
Domain Architecture	No domain graphic available
Description	Beta crystallin B1 [Contains: Beta crystallin B1B].

ARSI_HUMAN
NC score	0.012767 (rank : 14)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q5FYB1	Gene names	ARSI
Domain Architecture	No domain graphic available
Description	Arylsulfatase I precursor (EC 3.1.6.-) (ASI).