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Network neighborhood for query Sequence : KPYR_HUMAN

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KPYR_HUMAN
SwissProt Accessions	P30613, P11973	Gene names	PKLR, PK1, PKL
Domain Architecture
Description	Pyruvate kinase isozymes R/L (EC 2.7.1.40) (R-type/L-type pyruvate kinase) (Red cell/liver pyruvate kinase) (Pyruvate kinase 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KPYM_HUMAN
θ value	0 (rank : 1)	NC score	0.994806 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P14618, P14786, Q96E76, Q9BWB5, Q9UPF2	Gene names	PKM2, PK2, PK3, PKM
Domain Architecture
Description	Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Pyruvate kinase 2/3) (Cytosolic thyroid hormone-binding protein) (CTHBP) (THBP1).

KPYM_MOUSE
θ value	0 (rank : 2)	NC score	0.994393 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	P52480, Q64484, Q91YI8	Gene names	Pkm2, Pk3, Pykm
Domain Architecture
Description	Pyruvate kinase isozyme M2 (EC 2.7.1.40).

KPYR_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P30613, P11973	Gene names	PKLR, PK1, PKL
Domain Architecture
Description	Pyruvate kinase isozymes R/L (EC 2.7.1.40) (R-type/L-type pyruvate kinase) (Red cell/liver pyruvate kinase) (Pyruvate kinase 1).

KPYR_MOUSE
θ value	0 (rank : 4)	NC score	0.999228 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P53657	Gene names	Pklr
Domain Architecture
Description	Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK).

ITA7_HUMAN
θ value	1.81305 (rank : 5)	NC score	0.011198 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q13683, O43197, Q9NY89, Q9UET0, Q9UEV2	Gene names	ITGA7
Domain Architecture
Description	Integrin alpha-7 precursor [Contains: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain].

SELPL_MOUSE
θ value	2.36792 (rank : 6)	NC score	0.015019 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	588	Shared Neighborhood Hits	2
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ARID2_HUMAN
θ value	5.27518 (rank : 7)	NC score	0.015220 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	302	Shared Neighborhood Hits	2
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

GRIP2_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.008101 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	256	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

CK5P2_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.002664 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	1433	Shared Neighborhood Hits	2
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

THOC4_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.010847 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q86V81, O43672	Gene names	THOC4, ALY, BEF
Domain Architecture
Description	THO complex subunit 4 (Tho4) (Ally of AML-1 and LEF-1) (Transcriptional coactivator Aly/REF) (bZIP-enhancing factor BEF).

THOC4_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.010862 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	O08583, Q8CBM4, Q9JJW7	Gene names	Thoc4, Aly, Ref1, Refbp1
Domain Architecture
Description	THO complex subunit 4 (Tho4) (RNA and export factor-binding protein 1) (REF1-I) (Ally of AML-1 and LEF-1) (Aly/REF).

Hits sorted by NC score

KPYR_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P30613, P11973	Gene names	PKLR, PK1, PKL
Domain Architecture
Description	Pyruvate kinase isozymes R/L (EC 2.7.1.40) (R-type/L-type pyruvate kinase) (Red cell/liver pyruvate kinase) (Pyruvate kinase 1).

KPYR_MOUSE
NC score	0.999228 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P53657	Gene names	Pklr
Domain Architecture
Description	Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK).

KPYM_HUMAN
NC score	0.994806 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P14618, P14786, Q96E76, Q9BWB5, Q9UPF2	Gene names	PKM2, PK2, PK3, PKM
Domain Architecture
Description	Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Pyruvate kinase 2/3) (Cytosolic thyroid hormone-binding protein) (CTHBP) (THBP1).

KPYM_MOUSE
NC score	0.994393 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	P52480, Q64484, Q91YI8	Gene names	Pkm2, Pk3, Pykm
Domain Architecture
Description	Pyruvate kinase isozyme M2 (EC 2.7.1.40).

ARID2_HUMAN
NC score	0.015220 (rank : 5)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	302	Shared Neighborhood Hits	2
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

SELPL_MOUSE
NC score	0.015019 (rank : 6)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	588	Shared Neighborhood Hits	2
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ITA7_HUMAN
NC score	0.011198 (rank : 7)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q13683, O43197, Q9NY89, Q9UET0, Q9UEV2	Gene names	ITGA7
Domain Architecture
Description	Integrin alpha-7 precursor [Contains: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain].

THOC4_MOUSE
NC score	0.010862 (rank : 8)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	O08583, Q8CBM4, Q9JJW7	Gene names	Thoc4, Aly, Ref1, Refbp1
Domain Architecture
Description	THO complex subunit 4 (Tho4) (RNA and export factor-binding protein 1) (REF1-I) (Ally of AML-1 and LEF-1) (Aly/REF).

THOC4_HUMAN
NC score	0.010847 (rank : 9)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q86V81, O43672	Gene names	THOC4, ALY, BEF
Domain Architecture
Description	THO complex subunit 4 (Tho4) (Ally of AML-1 and LEF-1) (Transcriptional coactivator Aly/REF) (bZIP-enhancing factor BEF).

GRIP2_HUMAN
NC score	0.008101 (rank : 10)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	256	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

CK5P2_HUMAN
NC score	0.002664 (rank : 11)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	1433	Shared Neighborhood Hits	2
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).