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Network neighborhood for query Sequence : KPYM_HUMAN

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KPYM_HUMAN
SwissProt Accessions	P14618, P14786, Q96E76, Q9BWB5, Q9UPF2	Gene names	PKM2, PK2, PK3, PKM
Domain Architecture
Description	Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Pyruvate kinase 2/3) (Cytosolic thyroid hormone-binding protein) (CTHBP) (THBP1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KPYM_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P14618, P14786, Q96E76, Q9BWB5, Q9UPF2	Gene names	PKM2, PK2, PK3, PKM
Domain Architecture
Description	Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Pyruvate kinase 2/3) (Cytosolic thyroid hormone-binding protein) (CTHBP) (THBP1).

KPYM_MOUSE
θ value	0 (rank : 2)	NC score	0.999771 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P52480, Q64484, Q91YI8	Gene names	Pkm2, Pk3, Pykm
Domain Architecture
Description	Pyruvate kinase isozyme M2 (EC 2.7.1.40).

KPYR_HUMAN
θ value	0 (rank : 3)	NC score	0.994806 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P30613, P11973	Gene names	PKLR, PK1, PKL
Domain Architecture
Description	Pyruvate kinase isozymes R/L (EC 2.7.1.40) (R-type/L-type pyruvate kinase) (Red cell/liver pyruvate kinase) (Pyruvate kinase 1).

KPYR_MOUSE
θ value	0 (rank : 4)	NC score	0.995100 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P53657	Gene names	Pklr
Domain Architecture
Description	Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK).

CCD44_HUMAN
θ value	2.36792 (rank : 5)	NC score	0.039070 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSH4, Q8N3N6, Q9UI60	Gene names	CCDC44
Domain Architecture
Description	Coiled-coil domain-containing protein 44.

TFR1_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.025011 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P02786, Q59G55, Q9UCN0, Q9UCU5, Q9UDF9, Q9UK21	Gene names	TFRC
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen) (T9) (p90).

TFR1_MOUSE
θ value	5.27518 (rank : 8)	NC score	0.020560 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q62351, Q61560	Gene names	Tfrc, Trfr
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen).

DCC_MOUSE
θ value	8.99809 (rank : 10)	NC score	0.004003 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	896	Shared Neighborhood Hits	3
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

Hits sorted by NC score

KPYM_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P14618, P14786, Q96E76, Q9BWB5, Q9UPF2	Gene names	PKM2, PK2, PK3, PKM
Domain Architecture
Description	Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Pyruvate kinase 2/3) (Cytosolic thyroid hormone-binding protein) (CTHBP) (THBP1).

KPYM_MOUSE
NC score	0.999771 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P52480, Q64484, Q91YI8	Gene names	Pkm2, Pk3, Pykm
Domain Architecture
Description	Pyruvate kinase isozyme M2 (EC 2.7.1.40).

KPYR_MOUSE
NC score	0.995100 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P53657	Gene names	Pklr
Domain Architecture
Description	Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK).

KPYR_HUMAN
NC score	0.994806 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P30613, P11973	Gene names	PKLR, PK1, PKL
Domain Architecture
Description	Pyruvate kinase isozymes R/L (EC 2.7.1.40) (R-type/L-type pyruvate kinase) (Red cell/liver pyruvate kinase) (Pyruvate kinase 1).

CCD44_HUMAN
NC score	0.039070 (rank : 5)	θ value	2.36792 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSH4, Q8N3N6, Q9UI60	Gene names	CCDC44
Domain Architecture
Description	Coiled-coil domain-containing protein 44.

TFR1_HUMAN
NC score	0.025011 (rank : 7)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P02786, Q59G55, Q9UCN0, Q9UCU5, Q9UDF9, Q9UK21	Gene names	TFRC
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen) (T9) (p90).

TFR1_MOUSE
NC score	0.020560 (rank : 8)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q62351, Q61560	Gene names	Tfrc, Trfr
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen).

DCC_MOUSE
NC score	0.004003 (rank : 9)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	896	Shared Neighborhood Hits	3
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).