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Network neighborhood for query Sequence : IPP1_HUMAN

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IPP1_HUMAN
SwissProt Accessions	Q13522, Q8TBJ2	Gene names	PPP1R1A, IPP1
Domain Architecture
Description	Protein phosphatase inhibitor 1 (IPP-1) (I-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IPP1_HUMAN
θ value	3.11973e-85 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q13522, Q8TBJ2	Gene names	PPP1R1A, IPP1
Domain Architecture
Description	Protein phosphatase inhibitor 1 (IPP-1) (I-1).

IPP1_MOUSE
θ value	4.84666e-62 (rank : 2)	NC score	0.967131 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERT9	Gene names	Ppp1r1a
Domain Architecture
Description	Protein phosphatase inhibitor 1 (IPP-1) (I-1).

IPPD_HUMAN
θ value	5.26297e-08 (rank : 3)	NC score	0.522494 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UD71, Q9H7G1	Gene names	PPP1R1B, DARPP32
Domain Architecture	No domain graphic available
Description	Dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32).

IPPD_MOUSE
θ value	1.29631e-06 (rank : 4)	NC score	0.508356 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q60829, Q91XB5	Gene names	Ppp1r1b
Domain Architecture	No domain graphic available
Description	Dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32).

MLL3_MOUSE
θ value	0.163984 (rank : 5)	NC score	0.059616 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	1399	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NCOA6_MOUSE
θ value	0.62314 (rank : 6)	NC score	0.042989 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	1076	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MLL3_HUMAN
θ value	1.06291 (rank : 7)	NC score	0.052629 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	1644	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PCLO_MOUSE
θ value	1.38821 (rank : 8)	NC score	0.023530 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	2275	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MRP5_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.013560 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

PTCD1_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.041336 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

SETBP_MOUSE
θ value	3.0926 (rank : 11)	NC score	0.066965 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	352	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

K0241_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.032499 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q80U56	Gene names	Kiaa0241
Domain Architecture	No domain graphic available
Description	Protein KIAA0241.

RFX1_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.022309 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	256	Shared Neighborhood Hits	5
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

ROBO2_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.006564 (rank : 17)
Query Neighborhood Hits	16	Target Neighborhood Hits	504	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

TLN2_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.015539 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	149	Shared Neighborhood Hits	2
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

CB013_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.020926 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D842, Q8BZL5, Q99LX6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13 homolog.

SETBP_HUMAN
θ value	θ > 10 (rank : 17)	NC score	0.050054 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	305	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

Hits sorted by NC score

IPP1_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.11973e-85 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q13522, Q8TBJ2	Gene names	PPP1R1A, IPP1
Domain Architecture
Description	Protein phosphatase inhibitor 1 (IPP-1) (I-1).

IPP1_MOUSE
NC score	0.967131 (rank : 2)	θ value	4.84666e-62 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERT9	Gene names	Ppp1r1a
Domain Architecture
Description	Protein phosphatase inhibitor 1 (IPP-1) (I-1).

IPPD_HUMAN
NC score	0.522494 (rank : 3)	θ value	5.26297e-08 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UD71, Q9H7G1	Gene names	PPP1R1B, DARPP32
Domain Architecture	No domain graphic available
Description	Dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32).

IPPD_MOUSE
NC score	0.508356 (rank : 4)	θ value	1.29631e-06 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q60829, Q91XB5	Gene names	Ppp1r1b
Domain Architecture	No domain graphic available
Description	Dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32).

SETBP_MOUSE
NC score	0.066965 (rank : 5)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	352	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

MLL3_MOUSE
NC score	0.059616 (rank : 6)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	1399	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
NC score	0.052629 (rank : 7)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	1644	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SETBP_HUMAN
NC score	0.050054 (rank : 8)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	16	Target Neighborhood Hits	305	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

NCOA6_MOUSE
NC score	0.042989 (rank : 9)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	1076	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PTCD1_HUMAN
NC score	0.041336 (rank : 10)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

K0241_MOUSE
NC score	0.032499 (rank : 11)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q80U56	Gene names	Kiaa0241
Domain Architecture	No domain graphic available
Description	Protein KIAA0241.

PCLO_MOUSE
NC score	0.023530 (rank : 12)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	2275	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RFX1_HUMAN
NC score	0.022309 (rank : 13)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	256	Shared Neighborhood Hits	5
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

CB013_MOUSE
NC score	0.020926 (rank : 14)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D842, Q8BZL5, Q99LX6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13 homolog.

TLN2_MOUSE
NC score	0.015539 (rank : 15)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	149	Shared Neighborhood Hits	2
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

MRP5_HUMAN
NC score	0.013560 (rank : 16)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

ROBO2_MOUSE
NC score	0.006564 (rank : 17)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	504	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.