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Network neighborhood for query Sequence : HPS6_HUMAN

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HPS6_HUMAN
SwissProt Accessions	Q86YV9, Q9H685	Gene names	HPS6
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 6 protein (Ruby-eye protein homolog) (Ru).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HPS6_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q86YV9, Q9H685	Gene names	HPS6
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 6 protein (Ruby-eye protein homolog) (Ru).

HPS6_MOUSE
θ value	0 (rank : 2)	NC score	0.990116 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BLY7, Q8BML5, Q8CIA3	Gene names	Hps6, Ru
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 6 protein homolog (Ruby-eye protein) (Ru).

IGSF2_HUMAN
θ value	0.21417 (rank : 3)	NC score	0.049566 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	208	Shared Neighborhood Hits	2
SwissProt Accessions	Q93033, Q15856	Gene names	IGSF2, CD101, EWI101, V7
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 2 precursor (Glu-Trp-Ile EWI motif- containing protein 101) (EWI-101) (Cell surface glycoprotein V7) (CD101 antigen).

PKDRE_HUMAN
θ value	0.21417 (rank : 4)	NC score	0.046115 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

MBD5_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.049549 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

TM11E_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.007765 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	181	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

K0690_MOUSE
θ value	4.03905 (rank : 7)	NC score	0.032423 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P5B0, Q7TMI5, Q80TU2	Gene names	Kiaa0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

KCC2B_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.001932 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	866	Shared Neighborhood Hits	3
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

MATK_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.001934 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	954	Shared Neighborhood Hits	3
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

ZN524_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.001741 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	707	Shared Neighborhood Hits	2
SwissProt Accessions	Q96C55, Q6NW31, Q96IL7	Gene names	ZNF524
Domain Architecture	No domain graphic available
Description	Zinc finger protein 524.

CSPG3_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.005377 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	676	Shared Neighborhood Hits	3
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

EMID2_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.010113 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

K0690_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.029304 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JTH9, Q5JTH8, Q69YK4, Q96E87, Q9BUH3, Q9Y4C7	Gene names	KIAA0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

ABCBA_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.008024 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRK6, Q13040, Q9H3V0	Gene names	ABCB10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2).

ARMX2_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.009368 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

BAT3_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.012115 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	490	Shared Neighborhood Hits	4
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

SYNE1_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.003732 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	1484	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

Hits sorted by NC score

HPS6_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q86YV9, Q9H685	Gene names	HPS6
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 6 protein (Ruby-eye protein homolog) (Ru).

HPS6_MOUSE
NC score	0.990116 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BLY7, Q8BML5, Q8CIA3	Gene names	Hps6, Ru
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 6 protein homolog (Ruby-eye protein) (Ru).

IGSF2_HUMAN
NC score	0.049566 (rank : 3)	θ value	0.21417 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	208	Shared Neighborhood Hits	2
SwissProt Accessions	Q93033, Q15856	Gene names	IGSF2, CD101, EWI101, V7
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 2 precursor (Glu-Trp-Ile EWI motif- containing protein 101) (EWI-101) (Cell surface glycoprotein V7) (CD101 antigen).

MBD5_HUMAN
NC score	0.049549 (rank : 4)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

PKDRE_HUMAN
NC score	0.046115 (rank : 5)	θ value	0.21417 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

K0690_MOUSE
NC score	0.032423 (rank : 6)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P5B0, Q7TMI5, Q80TU2	Gene names	Kiaa0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

K0690_HUMAN
NC score	0.029304 (rank : 7)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JTH9, Q5JTH8, Q69YK4, Q96E87, Q9BUH3, Q9Y4C7	Gene names	KIAA0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

BAT3_HUMAN
NC score	0.012115 (rank : 8)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	490	Shared Neighborhood Hits	4
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

EMID2_MOUSE
NC score	0.010113 (rank : 9)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

ARMX2_HUMAN
NC score	0.009368 (rank : 10)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

ABCBA_HUMAN
NC score	0.008024 (rank : 11)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRK6, Q13040, Q9H3V0	Gene names	ABCB10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2).

TM11E_HUMAN
NC score	0.007765 (rank : 12)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	181	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

CSPG3_HUMAN
NC score	0.005377 (rank : 13)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	676	Shared Neighborhood Hits	3
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

SYNE1_HUMAN
NC score	0.003732 (rank : 14)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	1484	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

MATK_HUMAN
NC score	0.001934 (rank : 15)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	954	Shared Neighborhood Hits	3
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

KCC2B_HUMAN
NC score	0.001932 (rank : 16)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	866	Shared Neighborhood Hits	3
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

ZN524_HUMAN
NC score	0.001741 (rank : 17)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	707	Shared Neighborhood Hits	2
SwissProt Accessions	Q96C55, Q6NW31, Q96IL7	Gene names	ZNF524
Domain Architecture	No domain graphic available
Description	Zinc finger protein 524.