Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : HPPD_HUMAN

For an explanation of this page, click here

HPPD_HUMAN
SwissProt Accessions	P32754, Q13234	Gene names	HPD, PPD
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (HPPDase) (4-hydroxyphenylpyruvic acid oxidase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HPPD_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P32754, Q13234	Gene names	HPD, PPD
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (HPPDase) (4-hydroxyphenylpyruvic acid oxidase).

HPPD_MOUSE
θ value	0 (rank : 2)	NC score	0.997396 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	P49429, P97322, Q3UEQ0, Q91WV9	Gene names	Hpd
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (4- hydroxyphenylpyruvic acid oxidase) (HPPDase) (F protein) (F Alloantigen).

TITIN_HUMAN
θ value	0.0961366 (rank : 3)	NC score	0.019335 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	2923	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

41_HUMAN
θ value	1.06291 (rank : 4)	NC score	0.020435 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

MACF1_HUMAN
θ value	1.81305 (rank : 5)	NC score	0.020560 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	1341	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.023737 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	1321	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

STAT3_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.020364 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	P40763, O14916, Q9BW54	Gene names	STAT3, APRF
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT3_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.020364 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	P42227	Gene names	Stat3, Aprf
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

ALD1_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.010451 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P21300	Gene names	Akr1b7, Avdp
Domain Architecture
Description	Aldose reductase-related protein 1 (EC 1.1.1.21) (AR) (Aldehyde reductase) (VAS deferens androgen-dependent protein) (MVDP) (Aldo-keto reductase family 1 member B7).

MACF1_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.018686 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	1313	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

EST1A_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.016227 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

Hits sorted by NC score

HPPD_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P32754, Q13234	Gene names	HPD, PPD
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (HPPDase) (4-hydroxyphenylpyruvic acid oxidase).

HPPD_MOUSE
NC score	0.997396 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	P49429, P97322, Q3UEQ0, Q91WV9	Gene names	Hpd
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (4- hydroxyphenylpyruvic acid oxidase) (HPPDase) (F protein) (F Alloantigen).

MACF4_HUMAN
NC score	0.023737 (rank : 3)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	1321	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_HUMAN
NC score	0.020560 (rank : 4)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	1341	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

41_HUMAN
NC score	0.020435 (rank : 5)	θ value	1.06291 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

STAT3_MOUSE
NC score	0.020364 (rank : 6)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	P42227	Gene names	Stat3, Aprf
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT3_HUMAN
NC score	0.020364 (rank : 7)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	P40763, O14916, Q9BW54	Gene names	STAT3, APRF
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

TITIN_HUMAN
NC score	0.019335 (rank : 8)	θ value	0.0961366 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	2923	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MACF1_MOUSE
NC score	0.018686 (rank : 9)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	1313	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

EST1A_MOUSE
NC score	0.016227 (rank : 10)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

ALD1_MOUSE
NC score	0.010451 (rank : 11)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P21300	Gene names	Akr1b7, Avdp
Domain Architecture
Description	Aldose reductase-related protein 1 (EC 1.1.1.21) (AR) (Aldehyde reductase) (VAS deferens androgen-dependent protein) (MVDP) (Aldo-keto reductase family 1 member B7).