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Network neighborhood for query Sequence : HMCS2_HUMAN

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HMCS2_HUMAN
SwissProt Accessions	P54868	Gene names	HMGCS2
Domain Architecture
Description	Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor (EC 2.3.3.10) (HMG-CoA synthase) (3-hydroxy-3-methylglutaryl coenzyme A synthase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HMCS1_HUMAN
θ value	0 (rank : 1)	NC score	0.992056 (rank : 3)
Query Neighborhood Hits	7	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q01581	Gene names	HMGCS1, HMGCS
Domain Architecture
Description	Hydroxymethylglutaryl-CoA synthase, cytoplasmic (EC 2.3.3.10) (HMG-CoA synthase) (3-hydroxy-3-methylglutaryl coenzyme A synthase).

HMCS1_MOUSE
θ value	0 (rank : 2)	NC score	0.991633 (rank : 4)
Query Neighborhood Hits	7	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8JZK9, Q3UXI4	Gene names	Hmgcs1
Domain Architecture	No domain graphic available
Description	Hydroxymethylglutaryl-CoA synthase, cytoplasmic (EC 2.3.3.10) (HMG-CoA synthase) (3-hydroxy-3-methylglutaryl coenzyme A synthase).

HMCS2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	P54868	Gene names	HMGCS2
Domain Architecture
Description	Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor (EC 2.3.3.10) (HMG-CoA synthase) (3-hydroxy-3-methylglutaryl coenzyme A synthase).

HMCS2_MOUSE
θ value	0 (rank : 4)	NC score	0.999615 (rank : 2)
Query Neighborhood Hits	7	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	P54869, Q64740, Q9DBK1, Q9DBM4	Gene names	Hmgcs2
Domain Architecture	No domain graphic available
Description	Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor (EC 2.3.3.10) (HMG-CoA synthase) (3-hydroxy-3-methylglutaryl coenzyme A synthase).

PPHLN_MOUSE
θ value	0.813845 (rank : 5)	NC score	0.059803 (rank : 5)
Query Neighborhood Hits	7	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2H1, Q8BUZ6	Gene names	Pphln1
Domain Architecture	No domain graphic available
Description	Periphilin-1.

APLP1_HUMAN
θ value	5.27518 (rank : 6)	NC score	0.012396 (rank : 7)
Query Neighborhood Hits	7	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P51693, O00113, Q96A92	Gene names	APLP1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

S40A1_HUMAN
θ value	6.88961 (rank : 7)	NC score	0.014609 (rank : 6)
Query Neighborhood Hits	7	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP59, Q7Z4F8, Q8IVB2, Q9NRL0	Gene names	SLC40A1, FPN1, IREG1, SLC11A3
Domain Architecture
Description	Solute carrier family 40 member 1 (Ferroportin-1) (Iron-regulated transporter 1).

Hits sorted by NC score

HMCS2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	P54868	Gene names	HMGCS2
Domain Architecture
Description	Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor (EC 2.3.3.10) (HMG-CoA synthase) (3-hydroxy-3-methylglutaryl coenzyme A synthase).

HMCS2_MOUSE
NC score	0.999615 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	7	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	P54869, Q64740, Q9DBK1, Q9DBM4	Gene names	Hmgcs2
Domain Architecture	No domain graphic available
Description	Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor (EC 2.3.3.10) (HMG-CoA synthase) (3-hydroxy-3-methylglutaryl coenzyme A synthase).

HMCS1_HUMAN
NC score	0.992056 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	7	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q01581	Gene names	HMGCS1, HMGCS
Domain Architecture
Description	Hydroxymethylglutaryl-CoA synthase, cytoplasmic (EC 2.3.3.10) (HMG-CoA synthase) (3-hydroxy-3-methylglutaryl coenzyme A synthase).

HMCS1_MOUSE
NC score	0.991633 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	7	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8JZK9, Q3UXI4	Gene names	Hmgcs1
Domain Architecture	No domain graphic available
Description	Hydroxymethylglutaryl-CoA synthase, cytoplasmic (EC 2.3.3.10) (HMG-CoA synthase) (3-hydroxy-3-methylglutaryl coenzyme A synthase).

PPHLN_MOUSE
NC score	0.059803 (rank : 5)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	7	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2H1, Q8BUZ6	Gene names	Pphln1
Domain Architecture	No domain graphic available
Description	Periphilin-1.

S40A1_HUMAN
NC score	0.014609 (rank : 6)	θ value	6.88961 (rank : 7)
Query Neighborhood Hits	7	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP59, Q7Z4F8, Q8IVB2, Q9NRL0	Gene names	SLC40A1, FPN1, IREG1, SLC11A3
Domain Architecture
Description	Solute carrier family 40 member 1 (Ferroportin-1) (Iron-regulated transporter 1).

APLP1_HUMAN
NC score	0.012396 (rank : 7)	θ value	5.27518 (rank : 6)
Query Neighborhood Hits	7	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P51693, O00113, Q96A92	Gene names	APLP1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].