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Network neighborhood for query Sequence : F126A_HUMAN

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F126A_HUMAN
SwissProt Accessions	Q9BYI3, Q6N010, Q75MR4, Q7LDZ4, Q96MX1, Q96NQ6	Gene names	FAM126A, DRCTNNB1A
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

F126A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYI3, Q6N010, Q75MR4, Q7LDZ4, Q96MX1, Q96NQ6	Gene names	FAM126A, DRCTNNB1A
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).

F126A_MOUSE
θ value	0 (rank : 2)	NC score	0.997096 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P9N1, Q99NC4	Gene names	Fam126a, Drctnnb1a
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).

FA21C_HUMAN
θ value	0.0148317 (rank : 3)	NC score	0.134269 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

RPTOR_MOUSE
θ value	0.47712 (rank : 4)	NC score	0.079442 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4Q0, Q8C9W9, Q8CBY4, Q8CDY8, Q9D4H3	Gene names	Raptor
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

RPTOR_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.075263 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N122, Q8N4V9, Q8TB32, Q9P2P3	Gene names	RAPTOR, KIAA1303
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

SYP2L_MOUSE
θ value	1.06291 (rank : 6)	NC score	0.029532 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	289	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SETB1_HUMAN
θ value	2.36792 (rank : 7)	NC score	0.044593 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

ATRX_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.021077 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	842	Shared Neighborhood Hits	4
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

TLK2_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.006334 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	1044	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

TLK2_MOUSE
θ value	4.03905 (rank : 10)	NC score	0.006220 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	1088	Shared Neighborhood Hits	3
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

HUWE1_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.018883 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	443	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.018831 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	406	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

BARH2_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.006610 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	419	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

BARH2_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.006647 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	397	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VIB5, Q66L43	Gene names	Barhl2, Barh1, Mbh1
Domain Architecture	No domain graphic available
Description	BarH-like 2 homeobox protein (Bar-class homeodomain protein MBH1) (Homeobox protein B-H1).

Hits sorted by NC score

F126A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYI3, Q6N010, Q75MR4, Q7LDZ4, Q96MX1, Q96NQ6	Gene names	FAM126A, DRCTNNB1A
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).

F126A_MOUSE
NC score	0.997096 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P9N1, Q99NC4	Gene names	Fam126a, Drctnnb1a
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).

FA21C_HUMAN
NC score	0.134269 (rank : 3)	θ value	0.0148317 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

RPTOR_MOUSE
NC score	0.079442 (rank : 4)	θ value	0.47712 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4Q0, Q8C9W9, Q8CBY4, Q8CDY8, Q9D4H3	Gene names	Raptor
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

RPTOR_HUMAN
NC score	0.075263 (rank : 5)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N122, Q8N4V9, Q8TB32, Q9P2P3	Gene names	RAPTOR, KIAA1303
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

SETB1_HUMAN
NC score	0.044593 (rank : 6)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SYP2L_MOUSE
NC score	0.029532 (rank : 7)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	289	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ATRX_HUMAN
NC score	0.021077 (rank : 8)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	842	Shared Neighborhood Hits	4
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

HUWE1_HUMAN
NC score	0.018883 (rank : 9)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	443	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
NC score	0.018831 (rank : 10)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	406	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

BARH2_MOUSE
NC score	0.006647 (rank : 11)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	397	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VIB5, Q66L43	Gene names	Barhl2, Barh1, Mbh1
Domain Architecture	No domain graphic available
Description	BarH-like 2 homeobox protein (Bar-class homeodomain protein MBH1) (Homeobox protein B-H1).

BARH2_HUMAN
NC score	0.006610 (rank : 12)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	419	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

TLK2_HUMAN
NC score	0.006334 (rank : 13)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	1044	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

TLK2_MOUSE
NC score	0.006220 (rank : 14)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	1088	Shared Neighborhood Hits	3
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).