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Network neighborhood for query Sequence : ESTD_MOUSE

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ESTD_MOUSE
SwissProt Accessions	Q9R0P3, Q80ZX4, Q9CWI4	Gene names	Esd, Es10, Sid478
Domain Architecture	No domain graphic available
Description	S-formylglutathione hydrolase (EC 3.1.2.12) (FGH) (Esterase D) (Esterase 10) (Sid 478).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ESTD_MOUSE
θ value	9.15662e-170 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0P3, Q80ZX4, Q9CWI4	Gene names	Esd, Es10, Sid478
Domain Architecture	No domain graphic available
Description	S-formylglutathione hydrolase (EC 3.1.2.12) (FGH) (Esterase D) (Esterase 10) (Sid 478).

ESTD_HUMAN
θ value	6.1562e-158 (rank : 2)	NC score	0.994873 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P10768, Q5TBU8, Q5TBV0, Q5TBV2, Q9BVJ2	Gene names	ESD
Domain Architecture
Description	S-formylglutathione hydrolase (EC 3.1.2.12) (FGH) (Esterase D).

SEPR_HUMAN
θ value	0.0330416 (rank : 3)	NC score	0.105188 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q12884, O00199, Q86Z29, Q99998, Q9UID4	Gene names	FAP
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease) (170 kDa melanoma membrane-bound gelatinase).

SEPR_MOUSE
θ value	0.0431538 (rank : 4)	NC score	0.097244 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	P97321	Gene names	Fap
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease).

DPP10_MOUSE
θ value	0.62314 (rank : 5)	NC score	0.096094 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NXK7, Q6P554, Q8K1H0	Gene names	Dpp10
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X).

DPP10_HUMAN
θ value	1.06291 (rank : 6)	NC score	0.094868 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

EST1_MOUSE
θ value	4.03905 (rank : 7)	NC score	0.012016 (rank : 13)
Query Neighborhood Hits	9	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

SFRIP_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.028512 (rank : 11)
Query Neighborhood Hits	9	Target Neighborhood Hits	530	Shared Neighborhood Hits	3
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

EF1B_HUMAN
θ value	8.99809 (rank : 9)	NC score	0.015849 (rank : 12)
Query Neighborhood Hits	9	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P24534, Q6IBH9	Gene names	EEF1B2, EEF1B, EF1B
Domain Architecture
Description	Elongation factor 1-beta (EF-1-beta).

DPP4_HUMAN
θ value	θ > 10 (rank : 10)	NC score	0.068780 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	P27487	Gene names	DPP4, ADCP2, CD26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

DPP4_MOUSE
θ value	θ > 10 (rank : 11)	NC score	0.068919 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P28843, Q3U514	Gene names	Dpp4, Cd26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

DPP6_HUMAN
θ value	θ > 10 (rank : 12)	NC score	0.064676 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P42658	Gene names	DPP6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

DPP6_MOUSE
θ value	θ > 10 (rank : 13)	NC score	0.064502 (rank : 10)
Query Neighborhood Hits	9	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z218, Q9QWW2, Q9Z219	Gene names	Dpp6, Dpp-6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

Hits sorted by NC score

ESTD_MOUSE
NC score	0.999962 (rank : 1)	θ value	9.15662e-170 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0P3, Q80ZX4, Q9CWI4	Gene names	Esd, Es10, Sid478
Domain Architecture	No domain graphic available
Description	S-formylglutathione hydrolase (EC 3.1.2.12) (FGH) (Esterase D) (Esterase 10) (Sid 478).

ESTD_HUMAN
NC score	0.994873 (rank : 2)	θ value	6.1562e-158 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P10768, Q5TBU8, Q5TBV0, Q5TBV2, Q9BVJ2	Gene names	ESD
Domain Architecture
Description	S-formylglutathione hydrolase (EC 3.1.2.12) (FGH) (Esterase D).

SEPR_HUMAN
NC score	0.105188 (rank : 3)	θ value	0.0330416 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q12884, O00199, Q86Z29, Q99998, Q9UID4	Gene names	FAP
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease) (170 kDa melanoma membrane-bound gelatinase).

SEPR_MOUSE
NC score	0.097244 (rank : 4)	θ value	0.0431538 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	P97321	Gene names	Fap
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease).

DPP10_MOUSE
NC score	0.096094 (rank : 5)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NXK7, Q6P554, Q8K1H0	Gene names	Dpp10
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X).

DPP10_HUMAN
NC score	0.094868 (rank : 6)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

DPP4_MOUSE
NC score	0.068919 (rank : 7)	θ value	θ > 10 (rank : 11)
Query Neighborhood Hits	9	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P28843, Q3U514	Gene names	Dpp4, Cd26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

DPP4_HUMAN
NC score	0.068780 (rank : 8)	θ value	θ > 10 (rank : 10)
Query Neighborhood Hits	9	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	P27487	Gene names	DPP4, ADCP2, CD26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

DPP6_HUMAN
NC score	0.064676 (rank : 9)	θ value	θ > 10 (rank : 12)
Query Neighborhood Hits	9	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P42658	Gene names	DPP6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

DPP6_MOUSE
NC score	0.064502 (rank : 10)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	9	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z218, Q9QWW2, Q9Z219	Gene names	Dpp6, Dpp-6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

SFRIP_HUMAN
NC score	0.028512 (rank : 11)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	530	Shared Neighborhood Hits	3
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

EF1B_HUMAN
NC score	0.015849 (rank : 12)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P24534, Q6IBH9	Gene names	EEF1B2, EEF1B, EF1B
Domain Architecture
Description	Elongation factor 1-beta (EF-1-beta).

EST1_MOUSE
NC score	0.012016 (rank : 13)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).