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Network neighborhood for query Sequence : ESTD_HUMAN

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ESTD_HUMAN
SwissProt Accessions	P10768, Q5TBU8, Q5TBV0, Q5TBV2, Q9BVJ2	Gene names	ESD
Domain Architecture
Description	S-formylglutathione hydrolase (EC 3.1.2.12) (FGH) (Esterase D).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ESTD_HUMAN
θ value	4.85525e-171 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P10768, Q5TBU8, Q5TBV0, Q5TBV2, Q9BVJ2	Gene names	ESD
Domain Architecture
Description	S-formylglutathione hydrolase (EC 3.1.2.12) (FGH) (Esterase D).

ESTD_MOUSE
θ value	6.1562e-158 (rank : 2)	NC score	0.994873 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0P3, Q80ZX4, Q9CWI4	Gene names	Esd, Es10, Sid478
Domain Architecture	No domain graphic available
Description	S-formylglutathione hydrolase (EC 3.1.2.12) (FGH) (Esterase D) (Esterase 10) (Sid 478).

DPP10_HUMAN
θ value	0.365318 (rank : 3)	NC score	0.068332 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

DPP10_MOUSE
θ value	0.47712 (rank : 4)	NC score	0.069572 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NXK7, Q6P554, Q8K1H0	Gene names	Dpp10
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X).

PTN1_MOUSE
θ value	0.47712 (rank : 5)	NC score	0.018731 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

SEPR_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.062598 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q12884, O00199, Q86Z29, Q99998, Q9UID4	Gene names	FAP
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease) (170 kDa melanoma membrane-bound gelatinase).

SFRIP_HUMAN
θ value	5.27518 (rank : 7)	NC score	0.028632 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	530	Shared Neighborhood Hits	3
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

CSPG5_HUMAN
θ value	8.99809 (rank : 8)	NC score	0.015810 (rank : 9)
Query Neighborhood Hits	8	Target Neighborhood Hits	199	Shared Neighborhood Hits	2
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

SEPR_MOUSE
θ value	θ > 10 (rank : 9)	NC score	0.054506 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	P97321	Gene names	Fap
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease).

Hits sorted by NC score

ESTD_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.85525e-171 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P10768, Q5TBU8, Q5TBV0, Q5TBV2, Q9BVJ2	Gene names	ESD
Domain Architecture
Description	S-formylglutathione hydrolase (EC 3.1.2.12) (FGH) (Esterase D).

ESTD_MOUSE
NC score	0.994873 (rank : 2)	θ value	6.1562e-158 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0P3, Q80ZX4, Q9CWI4	Gene names	Esd, Es10, Sid478
Domain Architecture	No domain graphic available
Description	S-formylglutathione hydrolase (EC 3.1.2.12) (FGH) (Esterase D) (Esterase 10) (Sid 478).

DPP10_MOUSE
NC score	0.069572 (rank : 3)	θ value	0.47712 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NXK7, Q6P554, Q8K1H0	Gene names	Dpp10
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X).

DPP10_HUMAN
NC score	0.068332 (rank : 4)	θ value	0.365318 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

SEPR_HUMAN
NC score	0.062598 (rank : 5)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q12884, O00199, Q86Z29, Q99998, Q9UID4	Gene names	FAP
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease) (170 kDa melanoma membrane-bound gelatinase).

SEPR_MOUSE
NC score	0.054506 (rank : 6)	θ value	θ > 10 (rank : 9)
Query Neighborhood Hits	8	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	P97321	Gene names	Fap
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease).

SFRIP_HUMAN
NC score	0.028632 (rank : 7)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	530	Shared Neighborhood Hits	3
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

PTN1_MOUSE
NC score	0.018731 (rank : 8)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

CSPG5_HUMAN
NC score	0.015810 (rank : 9)	θ value	8.99809 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	199	Shared Neighborhood Hits	2
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).