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Network neighborhood for query Sequence : ERCC3_HUMAN

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ERCC3_HUMAN
SwissProt Accessions	P19447	Gene names	ERCC3, XPB, XPBC
Domain Architecture
Description	TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.1.-) (Basic transcription factor 2 89 kDa subunit) (BTF2-p89) (TFIIH 89 kDa subunit) (DNA-repair protein complementing XP-B cells) (Xeroderma pigmentosum group B-complementing protein) (DNA excision repair protein ERCC-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ERCC3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P19447	Gene names	ERCC3, XPB, XPBC
Domain Architecture
Description	TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.1.-) (Basic transcription factor 2 89 kDa subunit) (BTF2-p89) (TFIIH 89 kDa subunit) (DNA-repair protein complementing XP-B cells) (Xeroderma pigmentosum group B-complementing protein) (DNA excision repair protein ERCC-3).

ERCC3_MOUSE
θ value	0 (rank : 2)	NC score	0.995736 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	P49135	Gene names	Ercc3, Xpb, Xpbc
Domain Architecture
Description	TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.1.-) (Basic transcription factor 2 89 kDa subunit) (BTF2-p89) (TFIIH 89 kDa subunit) (DNA-repair protein complementing XP-B cells) (Xeroderma pigmentosum group B-complementing protein) (DNA excision repair protein ERCC-3).

SMRCD_MOUSE
θ value	0.0431538 (rank : 3)	NC score	0.056605 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

RA54B_MOUSE
θ value	0.163984 (rank : 4)	NC score	0.050665 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RFIP4_HUMAN
θ value	0.47712 (rank : 5)	NC score	0.030232 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	785	Shared Neighborhood Hits	6
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

CHD6_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.032796 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	342	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

IFIH1_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.035358 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

FLT3_MOUSE
θ value	1.81305 (rank : 8)	NC score	0.005797 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	847	Shared Neighborhood Hits	2
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

CHST9_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.019377 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q7L1S5, Q6UX69, Q9BXH3, Q9BXH4, Q9BZW9	Gene names	CHST9
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 9 (EC 2.8.2.-) (N-acetylgalactosamine-4- O-sulfotransferase 2) (GalNAc-4-O-sulfotransferase 2) (GalNAc-4-ST2).

DDX5_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.017331 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	3.0926 (rank : 11)	NC score	0.017353 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

PHLB1_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.022546 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	678	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RFIP4_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.026676 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	708	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

VAS1_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.048807 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1Q9	Gene names	Atp6ap1, Atp6ip1, Atp6s1
Domain Architecture
Description	Vacuolar ATP synthase subunit S1 precursor (EC 3.6.3.14) (V-ATPase S1 subunit) (V-ATPase S1 accessory protein) (V-ATPase Ac45 subunit) (C7-1 protein).

PHLB1_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.019859 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	1038	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

VAS1_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.041359 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q15904	Gene names	ATP6AP1, ATP6IP1, ATP6S1, VATPS1, XAP3
Domain Architecture
Description	Vacuolar ATP synthase subunit S1 precursor (EC 3.6.3.14) (V-ATPase S1 subunit) (V-ATPase S1 accessory protein) (V-ATPase Ac45 subunit) (XAP- 3).

KI67_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.012177 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	581	Shared Neighborhood Hits	3
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

TRIPB_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.006631 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	1587	Shared Neighborhood Hits	7
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

Hits sorted by NC score

ERCC3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P19447	Gene names	ERCC3, XPB, XPBC
Domain Architecture
Description	TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.1.-) (Basic transcription factor 2 89 kDa subunit) (BTF2-p89) (TFIIH 89 kDa subunit) (DNA-repair protein complementing XP-B cells) (Xeroderma pigmentosum group B-complementing protein) (DNA excision repair protein ERCC-3).

ERCC3_MOUSE
NC score	0.995736 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	P49135	Gene names	Ercc3, Xpb, Xpbc
Domain Architecture
Description	TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.1.-) (Basic transcription factor 2 89 kDa subunit) (BTF2-p89) (TFIIH 89 kDa subunit) (DNA-repair protein complementing XP-B cells) (Xeroderma pigmentosum group B-complementing protein) (DNA excision repair protein ERCC-3).

SMRCD_MOUSE
NC score	0.056605 (rank : 3)	θ value	0.0431538 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

RA54B_MOUSE
NC score	0.050665 (rank : 4)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

VAS1_MOUSE
NC score	0.048807 (rank : 5)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1Q9	Gene names	Atp6ap1, Atp6ip1, Atp6s1
Domain Architecture
Description	Vacuolar ATP synthase subunit S1 precursor (EC 3.6.3.14) (V-ATPase S1 subunit) (V-ATPase S1 accessory protein) (V-ATPase Ac45 subunit) (C7-1 protein).

VAS1_HUMAN
NC score	0.041359 (rank : 6)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q15904	Gene names	ATP6AP1, ATP6IP1, ATP6S1, VATPS1, XAP3
Domain Architecture
Description	Vacuolar ATP synthase subunit S1 precursor (EC 3.6.3.14) (V-ATPase S1 subunit) (V-ATPase S1 accessory protein) (V-ATPase Ac45 subunit) (XAP- 3).

IFIH1_HUMAN
NC score	0.035358 (rank : 7)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

CHD6_HUMAN
NC score	0.032796 (rank : 8)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	342	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

RFIP4_HUMAN
NC score	0.030232 (rank : 9)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	785	Shared Neighborhood Hits	6
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RFIP4_MOUSE
NC score	0.026676 (rank : 10)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	708	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

PHLB1_MOUSE
NC score	0.022546 (rank : 11)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	678	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_HUMAN
NC score	0.019859 (rank : 12)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	1038	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CHST9_HUMAN
NC score	0.019377 (rank : 13)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q7L1S5, Q6UX69, Q9BXH3, Q9BXH4, Q9BZW9	Gene names	CHST9
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 9 (EC 2.8.2.-) (N-acetylgalactosamine-4- O-sulfotransferase 2) (GalNAc-4-O-sulfotransferase 2) (GalNAc-4-ST2).

DDX5_MOUSE
NC score	0.017353 (rank : 14)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX5_HUMAN
NC score	0.017331 (rank : 15)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

KI67_HUMAN
NC score	0.012177 (rank : 16)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	581	Shared Neighborhood Hits	3
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

TRIPB_HUMAN
NC score	0.006631 (rank : 17)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	1587	Shared Neighborhood Hits	7
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

FLT3_MOUSE
NC score	0.005797 (rank : 18)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	847	Shared Neighborhood Hits	2
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).