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Network neighborhood for query Sequence : EDRF1_HUMAN

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EDRF1_HUMAN
SwissProt Accessions	Q3B7T1, Q4G190, Q8IZ74, Q9Y3W4	Gene names	EDRF1, C10orf137
Domain Architecture	No domain graphic available
Description	Erythroid differentiation-related factor 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EDRF1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q3B7T1, Q4G190, Q8IZ74, Q9Y3W4	Gene names	EDRF1, C10orf137
Domain Architecture	No domain graphic available
Description	Erythroid differentiation-related factor 1.

EDRF1_MOUSE
θ value	0 (rank : 2)	NC score	0.995269 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q6GQV7, Q80ZY3, Q8R3P5	Gene names	Edrf1
Domain Architecture	No domain graphic available
Description	Erythroid differentiation-related factor 1.

SIN3B_MOUSE
θ value	0.0563607 (rank : 3)	NC score	0.075155 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q62141, O54976, Q6A013, Q8VCB8, Q8VDZ5	Gene names	Sin3b, Kiaa0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

GCC2_MOUSE
θ value	1.06291 (rank : 4)	NC score	0.014639 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	1619	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

UT14B_MOUSE
θ value	1.06291 (rank : 5)	NC score	0.040060 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	226	Shared Neighborhood Hits	5
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

AKA12_HUMAN
θ value	3.0926 (rank : 6)	NC score	0.018846 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	825	Shared Neighborhood Hits	4
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CEP72_MOUSE
θ value	3.0926 (rank : 7)	NC score	0.026946 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	381	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

SPIB_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.029814 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q01892, Q15359	Gene names	SPIB
Domain Architecture
Description	Transcription factor Spi-B.

ZN292_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.015955 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	918	Shared Neighborhood Hits	3
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

BRCA1_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.021119 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	381	Shared Neighborhood Hits	5
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

EMIL3_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.015823 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	249	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

ABC8B_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.006753 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

HKR1_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.000546 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	759	Shared Neighborhood Hits	3
SwissProt Accessions	P10072, Q9BSW9, Q9UM09	Gene names	HKR1
Domain Architecture
Description	Krueppel-related zinc finger protein 1 (Protein HKR1).

LEO1_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.009659 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	958	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

SCML2_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.013526 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UQR0, Q86U98, Q8IWD0, Q8NDP2, Q9UGC5	Gene names	SCML2
Domain Architecture
Description	Sex comb on midleg-like protein 2.

THUM1_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.041819 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NXG2, Q9BWC3	Gene names	THUMPD1
Domain Architecture
Description	THUMP domain-containing protein 1.

STK39_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.001191 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	915	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

TF3C1_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.028504 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

UBE1L_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.019569 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

CD2L7_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.001040 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	1275	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

EPAS1_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.006590 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

NKTR_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.011380 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	658	Shared Neighborhood Hits	6
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NRAP_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.014644 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	Q86VF7, O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059, Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, Q86TE6, Q86VF6, Q8N3R6, Q8N8F9, Q8TCH0, Q96MG4	Gene names	NRAP
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

THUM1_MOUSE
θ value	8.99809 (rank : 24)	NC score	0.035225 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q99J36, Q3U6Y3	Gene names	Thumpd1
Domain Architecture
Description	THUMP domain-containing protein 1.

Hits sorted by NC score

EDRF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q3B7T1, Q4G190, Q8IZ74, Q9Y3W4	Gene names	EDRF1, C10orf137
Domain Architecture	No domain graphic available
Description	Erythroid differentiation-related factor 1.

EDRF1_MOUSE
NC score	0.995269 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q6GQV7, Q80ZY3, Q8R3P5	Gene names	Edrf1
Domain Architecture	No domain graphic available
Description	Erythroid differentiation-related factor 1.

SIN3B_MOUSE
NC score	0.075155 (rank : 3)	θ value	0.0563607 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q62141, O54976, Q6A013, Q8VCB8, Q8VDZ5	Gene names	Sin3b, Kiaa0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

THUM1_HUMAN
NC score	0.041819 (rank : 4)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NXG2, Q9BWC3	Gene names	THUMPD1
Domain Architecture
Description	THUMP domain-containing protein 1.

UT14B_MOUSE
NC score	0.040060 (rank : 5)	θ value	1.06291 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	226	Shared Neighborhood Hits	5
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

THUM1_MOUSE
NC score	0.035225 (rank : 6)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q99J36, Q3U6Y3	Gene names	Thumpd1
Domain Architecture
Description	THUMP domain-containing protein 1.

SPIB_HUMAN
NC score	0.029814 (rank : 7)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q01892, Q15359	Gene names	SPIB
Domain Architecture
Description	Transcription factor Spi-B.

TF3C1_HUMAN
NC score	0.028504 (rank : 8)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

CEP72_MOUSE
NC score	0.026946 (rank : 9)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	381	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

BRCA1_HUMAN
NC score	0.021119 (rank : 10)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	381	Shared Neighborhood Hits	5
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

UBE1L_HUMAN
NC score	0.019569 (rank : 11)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

AKA12_HUMAN
NC score	0.018846 (rank : 12)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	825	Shared Neighborhood Hits	4
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ZN292_HUMAN
NC score	0.015955 (rank : 13)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	918	Shared Neighborhood Hits	3
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

EMIL3_HUMAN
NC score	0.015823 (rank : 14)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	249	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

NRAP_HUMAN
NC score	0.014644 (rank : 15)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	Q86VF7, O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059, Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, Q86TE6, Q86VF6, Q8N3R6, Q8N8F9, Q8TCH0, Q96MG4	Gene names	NRAP
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

GCC2_MOUSE
NC score	0.014639 (rank : 16)	θ value	1.06291 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	1619	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

SCML2_HUMAN
NC score	0.013526 (rank : 17)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UQR0, Q86U98, Q8IWD0, Q8NDP2, Q9UGC5	Gene names	SCML2
Domain Architecture
Description	Sex comb on midleg-like protein 2.

NKTR_HUMAN
NC score	0.011380 (rank : 18)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	658	Shared Neighborhood Hits	6
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

LEO1_HUMAN
NC score	0.009659 (rank : 19)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	958	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

ABC8B_MOUSE
NC score	0.006753 (rank : 20)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

EPAS1_MOUSE
NC score	0.006590 (rank : 21)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

STK39_MOUSE
NC score	0.001191 (rank : 22)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	915	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

CD2L7_HUMAN
NC score	0.001040 (rank : 23)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	1275	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

HKR1_HUMAN
NC score	0.000546 (rank : 24)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	759	Shared Neighborhood Hits	3
SwissProt Accessions	P10072, Q9BSW9, Q9UM09	Gene names	HKR1
Domain Architecture
Description	Krueppel-related zinc finger protein 1 (Protein HKR1).