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Network neighborhood for query Sequence : EAPP_HUMAN

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EAPP_HUMAN
SwissProt Accessions	Q56P03, Q9BVF4, Q9NWV5, Q9NZ86	Gene names	EAPP, C14orf11
Domain Architecture	No domain graphic available
Description	E2F-associated phosphoprotein (EAPP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EAPP_HUMAN
θ value	1.2462e-142 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q56P03, Q9BVF4, Q9NWV5, Q9NZ86	Gene names	EAPP, C14orf11
Domain Architecture	No domain graphic available
Description	E2F-associated phosphoprotein (EAPP).

EAPP_MOUSE
θ value	8.13402e-118 (rank : 2)	NC score	0.994468 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q5BU09, Q9CZB5, Q9D914	Gene names	Eapp
Domain Architecture	No domain graphic available
Description	E2F-associated phosphoprotein (EAPP).

ZFYV1_HUMAN
θ value	0.62314 (rank : 3)	NC score	0.052975 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	166	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

CABIN_HUMAN
θ value	1.06291 (rank : 4)	NC score	0.050381 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	490	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

AN30A_HUMAN
θ value	1.38821 (rank : 5)	NC score	0.019476 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	1119	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

TAI12_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.042885 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H175	Gene names	TAIP12, C12orf22
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

TAI12_MOUSE
θ value	2.36792 (rank : 7)	NC score	0.042858 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGQ2, Q3UIH1	Gene names	Taip12
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

TF2AY_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.035939 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNN4	Gene names	GTF2A1LF, ALF
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

GOGB1_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.013801 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	2297	Shared Neighborhood Hits	13
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MMP12_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.009600 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	P39900	Gene names	MMP12, HME
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (HME) (Matrix metalloproteinase-12) (MMP-12) (Macrophage elastase) (ME).

ANR21_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.015822 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	864	Shared Neighborhood Hits	10
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

KI21A_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.007247 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	1543	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

PERQ1_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.025208 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	215	Shared Neighborhood Hits	7
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

POT15_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.015469 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	893	Shared Neighborhood Hits	8
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

DDX18_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.005802 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	124	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

LEO1_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.016915 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	958	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

SFPQ_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.013218 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	986	Shared Neighborhood Hits	9
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.013266 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	958	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

TEX14_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.007017 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	1333	Shared Neighborhood Hits	8
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TIF1B_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.010137 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	312	Shared Neighborhood Hits	4
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

Hits sorted by NC score

EAPP_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.2462e-142 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q56P03, Q9BVF4, Q9NWV5, Q9NZ86	Gene names	EAPP, C14orf11
Domain Architecture	No domain graphic available
Description	E2F-associated phosphoprotein (EAPP).

EAPP_MOUSE
NC score	0.994468 (rank : 2)	θ value	8.13402e-118 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q5BU09, Q9CZB5, Q9D914	Gene names	Eapp
Domain Architecture	No domain graphic available
Description	E2F-associated phosphoprotein (EAPP).

ZFYV1_HUMAN
NC score	0.052975 (rank : 3)	θ value	0.62314 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	166	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

CABIN_HUMAN
NC score	0.050381 (rank : 4)	θ value	1.06291 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	490	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

TAI12_HUMAN
NC score	0.042885 (rank : 5)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H175	Gene names	TAIP12, C12orf22
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

TAI12_MOUSE
NC score	0.042858 (rank : 6)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGQ2, Q3UIH1	Gene names	Taip12
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

TF2AY_HUMAN
NC score	0.035939 (rank : 7)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNN4	Gene names	GTF2A1LF, ALF
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

PERQ1_MOUSE
NC score	0.025208 (rank : 8)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	215	Shared Neighborhood Hits	7
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

AN30A_HUMAN
NC score	0.019476 (rank : 9)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	1119	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

LEO1_HUMAN
NC score	0.016915 (rank : 10)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	958	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

ANR21_HUMAN
NC score	0.015822 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	864	Shared Neighborhood Hits	10
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

POT15_HUMAN
NC score	0.015469 (rank : 12)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	893	Shared Neighborhood Hits	8
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

GOGB1_HUMAN
NC score	0.013801 (rank : 13)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	2297	Shared Neighborhood Hits	13
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SFPQ_MOUSE
NC score	0.013266 (rank : 14)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	958	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SFPQ_HUMAN
NC score	0.013218 (rank : 15)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	986	Shared Neighborhood Hits	9
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

TIF1B_HUMAN
NC score	0.010137 (rank : 16)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	312	Shared Neighborhood Hits	4
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

MMP12_HUMAN
NC score	0.009600 (rank : 17)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	P39900	Gene names	MMP12, HME
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (HME) (Matrix metalloproteinase-12) (MMP-12) (Macrophage elastase) (ME).

KI21A_HUMAN
NC score	0.007247 (rank : 18)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	1543	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

TEX14_MOUSE
NC score	0.007017 (rank : 19)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	1333	Shared Neighborhood Hits	8
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DDX18_HUMAN
NC score	0.005802 (rank : 20)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	124	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).