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Network neighborhood for query Sequence : DTD1_HUMAN

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DTD1_HUMAN
SwissProt Accessions	Q8TEA8, Q496D1, Q5W184, Q8WXU8, Q9BW67, Q9H464, Q9H474	Gene names	HARS2, C20orf88
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DTD1_HUMAN
θ value	3.41741e-116 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	50	Target Neighborhood Hits	50	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TEA8, Q496D1, Q5W184, Q8WXU8, Q9BW67, Q9H464, Q9H474	Gene names	HARS2, C20orf88
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

DTD1_MOUSE
θ value	5.46864e-106 (rank : 2)	NC score	0.987818 (rank : 2)
Query Neighborhood Hits	50	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DD18, Q9CRE8, Q9CYL0, Q9D013, Q9D1G4	Gene names	Hars2
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

NFL_HUMAN
θ value	0.125558 (rank : 3)	NC score	0.038126 (rank : 22)
Query Neighborhood Hits	50	Target Neighborhood Hits	666	Shared Neighborhood Hits	11
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

MK07_HUMAN
θ value	0.279714 (rank : 4)	NC score	0.017758 (rank : 45)
Query Neighborhood Hits	50	Target Neighborhood Hits	1087	Shared Neighborhood Hits	11
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

BSN_MOUSE
θ value	0.365318 (rank : 5)	NC score	0.053111 (rank : 10)
Query Neighborhood Hits	50	Target Neighborhood Hits	2057	Shared Neighborhood Hits	18
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NARG1_HUMAN
θ value	0.365318 (rank : 6)	NC score	0.083649 (rank : 4)
Query Neighborhood Hits	50	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXJ9, Q8IWH4, Q8NEV2, Q9H8P6	Gene names	NARG1, GA19, NATH, TBDN100
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase) (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen Ga19).

NARG1_MOUSE
θ value	0.365318 (rank : 7)	NC score	0.083853 (rank : 3)
Query Neighborhood Hits	50	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UM3, Q811Z9, Q9JID5	Gene names	Narg1, Nat1, Tbdn-1, Tubedown
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase 1) (Protein Tubedown-1).

NSBP1_MOUSE
θ value	0.365318 (rank : 8)	NC score	0.065690 (rank : 6)
Query Neighborhood Hits	50	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NCOR2_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.045240 (rank : 13)
Query Neighborhood Hits	50	Target Neighborhood Hits	870	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PRP4B_HUMAN
θ value	0.813845 (rank : 10)	NC score	0.019682 (rank : 42)
Query Neighborhood Hits	50	Target Neighborhood Hits	1030	Shared Neighborhood Hits	11
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

AP3B2_MOUSE
θ value	1.06291 (rank : 11)	NC score	0.038220 (rank : 21)
Query Neighborhood Hits	50	Target Neighborhood Hits	246	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

CN102_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.063230 (rank : 7)
Query Neighborhood Hits	50	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H7Z3, Q9NWH6	Gene names	C14orf102
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf102.

CS007_HUMAN
θ value	1.06291 (rank : 13)	NC score	0.072220 (rank : 5)
Query Neighborhood Hits	50	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

TRHY_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.022990 (rank : 35)
Query Neighborhood Hits	50	Target Neighborhood Hits	1385	Shared Neighborhood Hits	17
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

ANDR_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.023752 (rank : 34)
Query Neighborhood Hits	50	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ACINU_MOUSE
θ value	1.81305 (rank : 16)	NC score	0.045715 (rank : 12)
Query Neighborhood Hits	50	Target Neighborhood Hits	712	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

MK07_MOUSE
θ value	1.81305 (rank : 17)	NC score	0.015207 (rank : 47)
Query Neighborhood Hits	50	Target Neighborhood Hits	1054	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

BAZ2A_MOUSE
θ value	2.36792 (rank : 18)	NC score	0.030037 (rank : 30)
Query Neighborhood Hits	50	Target Neighborhood Hits	744	Shared Neighborhood Hits	13
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BSN_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.051599 (rank : 11)
Query Neighborhood Hits	50	Target Neighborhood Hits	1537	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CIR_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.042360 (rank : 16)
Query Neighborhood Hits	50	Target Neighborhood Hits	249	Shared Neighborhood Hits	6
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

NFH_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.033482 (rank : 27)
Query Neighborhood Hits	50	Target Neighborhood Hits	1242	Shared Neighborhood Hits	20
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PHF14_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.040771 (rank : 17)
Query Neighborhood Hits	50	Target Neighborhood Hits	447	Shared Neighborhood Hits	8
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

CSKI1_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.021106 (rank : 39)
Query Neighborhood Hits	50	Target Neighborhood Hits	1031	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NFL_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.030127 (rank : 29)
Query Neighborhood Hits	50	Target Neighborhood Hits	695	Shared Neighborhood Hits	11
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

NFM_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.027553 (rank : 31)
Query Neighborhood Hits	50	Target Neighborhood Hits	1328	Shared Neighborhood Hits	18
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PHF14_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.039765 (rank : 19)
Query Neighborhood Hits	50	Target Neighborhood Hits	342	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

SFRS5_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.038121 (rank : 23)
Query Neighborhood Hits	50	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q13243, O14797, Q16662	Gene names	SFRS5, HRS, SRP40
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

SFRS5_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.040485 (rank : 18)
Query Neighborhood Hits	50	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	O35326	Gene names	Sfrs5, Hrs
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

ANR11_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.019931 (rank : 41)
Query Neighborhood Hits	50	Target Neighborhood Hits	1289	Shared Neighborhood Hits	21
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

AP3B2_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.034161 (rank : 24)
Query Neighborhood Hits	50	Target Neighborhood Hits	246	Shared Neighborhood Hits	5
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

CN102_MOUSE
θ value	4.03905 (rank : 31)	NC score	0.055754 (rank : 9)
Query Neighborhood Hits	50	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XC6, Q8R3D7, Q99LT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf102 homolog.

NFH_MOUSE
θ value	4.03905 (rank : 32)	NC score	0.038259 (rank : 20)
Query Neighborhood Hits	50	Target Neighborhood Hits	2247	Shared Neighborhood Hits	34
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TERF2_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.032060 (rank : 28)
Query Neighborhood Hits	50	Target Neighborhood Hits	128	Shared Neighborhood Hits	8
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TITIN_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.011182 (rank : 49)
Query Neighborhood Hits	50	Target Neighborhood Hits	2923	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TXLNA_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.020300 (rank : 40)
Query Neighborhood Hits	50	Target Neighborhood Hits	982	Shared Neighborhood Hits	17
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

CS007_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.060170 (rank : 8)
Query Neighborhood Hits	50	Target Neighborhood Hits	464	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

T2FA_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.033694 (rank : 25)
Query Neighborhood Hits	50	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

VAPB_HUMAN
θ value	5.27518 (rank : 38)	NC score	0.043041 (rank : 15)
Query Neighborhood Hits	50	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	O95292, O95293, Q9P0H0	Gene names	VAPB
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B/C (VAMP- associated protein B/C) (VAMP-B/VAMP-C) (VAP-B/VAP-C).

ARS2_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.024348 (rank : 33)
Query Neighborhood Hits	50	Target Neighborhood Hits	186	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

CNGB3_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.017730 (rank : 46)
Query Neighborhood Hits	50	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

PMS2_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.018832 (rank : 43)
Query Neighborhood Hits	50	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

TCAL2_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.025226 (rank : 32)
Query Neighborhood Hits	50	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H3H9	Gene names	TCEAL2
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 2 (TCEA-like protein 2) (Transcription elongation factor S-II protein-like 2).

YBOX2_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.017811 (rank : 44)
Query Neighborhood Hits	50	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2T7, Q8N4P0	Gene names	YBX2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (Contrin) (MSY2 homolog).

CIR_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.033512 (rank : 26)
Query Neighborhood Hits	50	Target Neighborhood Hits	255	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

MMTA2_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.021526 (rank : 38)
Query Neighborhood Hits	50	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LX5, Q9CSK6	Gene names	Mmtag2
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 homolog.

PPIG_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.014273 (rank : 48)
Query Neighborhood Hits	50	Target Neighborhood Hits	670	Shared Neighborhood Hits	16
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RNPS1_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.022665 (rank : 36)
Query Neighborhood Hits	50	Target Neighborhood Hits	285	Shared Neighborhood Hits	6
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	8.99809 (rank : 48)	NC score	0.022665 (rank : 37)
Query Neighborhood Hits	50	Target Neighborhood Hits	285	Shared Neighborhood Hits	6
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

SPG7_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.010065 (rank : 50)
Query Neighborhood Hits	50	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

VAPB_MOUSE
θ value	8.99809 (rank : 50)	NC score	0.044042 (rank : 14)
Query Neighborhood Hits	50	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QY76	Gene names	Vapb
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B (VAMP- associated protein B) (VAMP-associated protein 33b) (VAMP-B) (VAP-B).

Hits sorted by NC score

DTD1_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.41741e-116 (rank : 1)
Query Neighborhood Hits	50	Target Neighborhood Hits	50	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TEA8, Q496D1, Q5W184, Q8WXU8, Q9BW67, Q9H464, Q9H474	Gene names	HARS2, C20orf88
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

DTD1_MOUSE
NC score	0.987818 (rank : 2)	θ value	5.46864e-106 (rank : 2)
Query Neighborhood Hits	50	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DD18, Q9CRE8, Q9CYL0, Q9D013, Q9D1G4	Gene names	Hars2
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

NARG1_MOUSE
NC score	0.083853 (rank : 3)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	50	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UM3, Q811Z9, Q9JID5	Gene names	Narg1, Nat1, Tbdn-1, Tubedown
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase 1) (Protein Tubedown-1).

NARG1_HUMAN
NC score	0.083649 (rank : 4)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	50	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXJ9, Q8IWH4, Q8NEV2, Q9H8P6	Gene names	NARG1, GA19, NATH, TBDN100
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase) (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen Ga19).

CS007_HUMAN
NC score	0.072220 (rank : 5)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	50	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

NSBP1_MOUSE
NC score	0.065690 (rank : 6)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	50	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

CN102_HUMAN
NC score	0.063230 (rank : 7)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	50	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H7Z3, Q9NWH6	Gene names	C14orf102
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf102.

CS007_MOUSE
NC score	0.060170 (rank : 8)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	50	Target Neighborhood Hits	464	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CN102_MOUSE
NC score	0.055754 (rank : 9)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	50	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XC6, Q8R3D7, Q99LT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf102 homolog.

BSN_MOUSE
NC score	0.053111 (rank : 10)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	50	Target Neighborhood Hits	2057	Shared Neighborhood Hits	18
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BSN_HUMAN
NC score	0.051599 (rank : 11)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	50	Target Neighborhood Hits	1537	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

ACINU_MOUSE
NC score	0.045715 (rank : 12)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	50	Target Neighborhood Hits	712	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

NCOR2_HUMAN
NC score	0.045240 (rank : 13)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	50	Target Neighborhood Hits	870	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

VAPB_MOUSE
NC score	0.044042 (rank : 14)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	50	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QY76	Gene names	Vapb
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B (VAMP- associated protein B) (VAMP-associated protein 33b) (VAMP-B) (VAP-B).

VAPB_HUMAN
NC score	0.043041 (rank : 15)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	50	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	O95292, O95293, Q9P0H0	Gene names	VAPB
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B/C (VAMP- associated protein B/C) (VAMP-B/VAMP-C) (VAP-B/VAP-C).

CIR_HUMAN
NC score	0.042360 (rank : 16)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	50	Target Neighborhood Hits	249	Shared Neighborhood Hits	6
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

PHF14_HUMAN
NC score	0.040771 (rank : 17)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	50	Target Neighborhood Hits	447	Shared Neighborhood Hits	8
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

SFRS5_MOUSE
NC score	0.040485 (rank : 18)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	50	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	O35326	Gene names	Sfrs5, Hrs
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

PHF14_MOUSE
NC score	0.039765 (rank : 19)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	50	Target Neighborhood Hits	342	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

NFH_MOUSE
NC score	0.038259 (rank : 20)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	50	Target Neighborhood Hits	2247	Shared Neighborhood Hits	34
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

AP3B2_MOUSE
NC score	0.038220 (rank : 21)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	50	Target Neighborhood Hits	246	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

NFL_HUMAN
NC score	0.038126 (rank : 22)	θ value	0.125558 (rank : 3)
Query Neighborhood Hits	50	Target Neighborhood Hits	666	Shared Neighborhood Hits	11
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

SFRS5_HUMAN
NC score	0.038121 (rank : 23)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	50	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q13243, O14797, Q16662	Gene names	SFRS5, HRS, SRP40
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

AP3B2_HUMAN
NC score	0.034161 (rank : 24)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	50	Target Neighborhood Hits	246	Shared Neighborhood Hits	5
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

T2FA_HUMAN
NC score	0.033694 (rank : 25)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	50	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

CIR_MOUSE
NC score	0.033512 (rank : 26)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	50	Target Neighborhood Hits	255	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

NFH_HUMAN
NC score	0.033482 (rank : 27)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	50	Target Neighborhood Hits	1242	Shared Neighborhood Hits	20
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TERF2_MOUSE
NC score	0.032060 (rank : 28)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	50	Target Neighborhood Hits	128	Shared Neighborhood Hits	8
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

NFL_MOUSE
NC score	0.030127 (rank : 29)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	50	Target Neighborhood Hits	695	Shared Neighborhood Hits	11
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

BAZ2A_MOUSE
NC score	0.030037 (rank : 30)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	50	Target Neighborhood Hits	744	Shared Neighborhood Hits	13
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

NFM_HUMAN
NC score	0.027553 (rank : 31)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	50	Target Neighborhood Hits	1328	Shared Neighborhood Hits	18
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

TCAL2_HUMAN
NC score	0.025226 (rank : 32)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	50	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H3H9	Gene names	TCEAL2
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 2 (TCEA-like protein 2) (Transcription elongation factor S-II protein-like 2).

ARS2_HUMAN
NC score	0.024348 (rank : 33)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	50	Target Neighborhood Hits	186	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

ANDR_HUMAN
NC score	0.023752 (rank : 34)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	50	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

TRHY_HUMAN
NC score	0.022990 (rank : 35)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	50	Target Neighborhood Hits	1385	Shared Neighborhood Hits	17
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

RNPS1_HUMAN
NC score	0.022665 (rank : 36)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	50	Target Neighborhood Hits	285	Shared Neighborhood Hits	6
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.022665 (rank : 37)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	50	Target Neighborhood Hits	285	Shared Neighborhood Hits	6
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

MMTA2_MOUSE
NC score	0.021526 (rank : 38)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	50	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LX5, Q9CSK6	Gene names	Mmtag2
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 homolog.

CSKI1_MOUSE
NC score	0.021106 (rank : 39)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	50	Target Neighborhood Hits	1031	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TXLNA_HUMAN
NC score	0.020300 (rank : 40)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	50	Target Neighborhood Hits	982	Shared Neighborhood Hits	17
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

ANR11_HUMAN
NC score	0.019931 (rank : 41)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	50	Target Neighborhood Hits	1289	Shared Neighborhood Hits	21
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

PRP4B_HUMAN
NC score	0.019682 (rank : 42)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	50	Target Neighborhood Hits	1030	Shared Neighborhood Hits	11
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

PMS2_MOUSE
NC score	0.018832 (rank : 43)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	50	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

YBOX2_HUMAN
NC score	0.017811 (rank : 44)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	50	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2T7, Q8N4P0	Gene names	YBX2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (Contrin) (MSY2 homolog).

MK07_HUMAN
NC score	0.017758 (rank : 45)	θ value	0.279714 (rank : 4)
Query Neighborhood Hits	50	Target Neighborhood Hits	1087	Shared Neighborhood Hits	11
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

CNGB3_HUMAN
NC score	0.017730 (rank : 46)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	50	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

MK07_MOUSE
NC score	0.015207 (rank : 47)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	50	Target Neighborhood Hits	1054	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

PPIG_HUMAN
NC score	0.014273 (rank : 48)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	50	Target Neighborhood Hits	670	Shared Neighborhood Hits	16
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

TITIN_HUMAN
NC score	0.011182 (rank : 49)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	50	Target Neighborhood Hits	2923	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SPG7_HUMAN
NC score	0.010065 (rank : 50)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	50	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).