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Network neighborhood for query Sequence : DCK_HUMAN

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DCK_HUMAN
SwissProt Accessions	P27707	Gene names	DCK
Domain Architecture
Description	Deoxycytidine kinase (EC 2.7.1.74) (dCK).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DCK_HUMAN
θ value	3.49569e-153 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P27707	Gene names	DCK
Domain Architecture
Description	Deoxycytidine kinase (EC 2.7.1.74) (dCK).

DCK_MOUSE
θ value	9.54178e-143 (rank : 2)	NC score	0.999178 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	P43346	Gene names	Dck
Domain Architecture
Description	Deoxycytidine kinase (EC 2.7.1.74) (dCK).

DGUOK_HUMAN
θ value	1.71981e-67 (rank : 3)	NC score	0.963449 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q16854, P78532, Q16759, Q96BC1	Gene names	DGUOK, DGK
Domain Architecture
Description	Deoxyguanosine kinase, mitochondrial precursor (EC 2.7.1.113) (dGK).

DGUOK_MOUSE
θ value	1.2325e-65 (rank : 4)	NC score	0.963421 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QX60, Q9R0Y2, Q9WUT9	Gene names	Dguok, Dgk
Domain Architecture
Description	Deoxyguanosine kinase, mitochondrial precursor (EC 2.7.1.113) (dGK).

KITM_HUMAN
θ value	2.77131e-33 (rank : 5)	NC score	0.875926 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	O00142, O15238	Gene names	TK2
Domain Architecture
Description	Thymidine kinase 2, mitochondrial precursor (EC 2.7.1.21) (Mt-TK).

KITM_MOUSE
θ value	1.37539e-32 (rank : 6)	NC score	0.874290 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R088	Gene names	Tk2
Domain Architecture
Description	Thymidine kinase 2, mitochondrial precursor (EC 2.7.1.21) (Mt-TK).

NDUAA_MOUSE
θ value	0.0961366 (rank : 7)	NC score	0.184612 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q99LC3, Q8BL57, Q9CW21	Gene names	Ndufa10
Domain Architecture
Description	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 42 kDa subunit) (Complex I-42kD) (CI-42kD).

CDK7_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.007565 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	833	Shared Neighborhood Hits	7
SwissProt Accessions	P50613, Q9BS60, Q9UE19	Gene names	CDK7, MO15
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1).

CDK7_MOUSE
θ value	1.81305 (rank : 9)	NC score	0.007601 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	835	Shared Neighborhood Hits	7
SwissProt Accessions	Q03147, Q99KK3	Gene names	Cdk7, Cdkn7, Crk4, Mo15, Mpk-7
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinase) (CRK4).

CRGA_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.008015 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P04345	Gene names	Cryga
Domain Architecture
Description	Gamma crystallin A (Gamma crystallin 4).

CD2L6_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.008007 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	844	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWU1, Q5JQZ7, Q5JR00, Q8TC78, Q9UPX2	Gene names	CDC2L6, CDK11, KIAA1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11).

CD2L6_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.008008 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	851	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

CDK8_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.007614 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	831	Shared Neighborhood Hits	7
SwissProt Accessions	P49336	Gene names	CDK8
Domain Architecture
Description	Cell division protein kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Protein kinase K35).

PGBM_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.001033 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	1113	Shared Neighborhood Hits	2
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NDUAA_HUMAN
θ value	θ > 10 (rank : 15)	NC score	0.095817 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	O95299	Gene names	NDUFA10
Domain Architecture
Description	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 42 kDa subunit) (Complex I-42kD) (CI-42kD).

Hits sorted by NC score

DCK_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.49569e-153 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P27707	Gene names	DCK
Domain Architecture
Description	Deoxycytidine kinase (EC 2.7.1.74) (dCK).

DCK_MOUSE
NC score	0.999178 (rank : 2)	θ value	9.54178e-143 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	P43346	Gene names	Dck
Domain Architecture
Description	Deoxycytidine kinase (EC 2.7.1.74) (dCK).

DGUOK_HUMAN
NC score	0.963449 (rank : 3)	θ value	1.71981e-67 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q16854, P78532, Q16759, Q96BC1	Gene names	DGUOK, DGK
Domain Architecture
Description	Deoxyguanosine kinase, mitochondrial precursor (EC 2.7.1.113) (dGK).

DGUOK_MOUSE
NC score	0.963421 (rank : 4)	θ value	1.2325e-65 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QX60, Q9R0Y2, Q9WUT9	Gene names	Dguok, Dgk
Domain Architecture
Description	Deoxyguanosine kinase, mitochondrial precursor (EC 2.7.1.113) (dGK).

KITM_HUMAN
NC score	0.875926 (rank : 5)	θ value	2.77131e-33 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	O00142, O15238	Gene names	TK2
Domain Architecture
Description	Thymidine kinase 2, mitochondrial precursor (EC 2.7.1.21) (Mt-TK).

KITM_MOUSE
NC score	0.874290 (rank : 6)	θ value	1.37539e-32 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R088	Gene names	Tk2
Domain Architecture
Description	Thymidine kinase 2, mitochondrial precursor (EC 2.7.1.21) (Mt-TK).

NDUAA_MOUSE
NC score	0.184612 (rank : 7)	θ value	0.0961366 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q99LC3, Q8BL57, Q9CW21	Gene names	Ndufa10
Domain Architecture
Description	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 42 kDa subunit) (Complex I-42kD) (CI-42kD).

NDUAA_HUMAN
NC score	0.095817 (rank : 8)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	O95299	Gene names	NDUFA10
Domain Architecture
Description	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 42 kDa subunit) (Complex I-42kD) (CI-42kD).

CRGA_MOUSE
NC score	0.008015 (rank : 9)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P04345	Gene names	Cryga
Domain Architecture
Description	Gamma crystallin A (Gamma crystallin 4).

CD2L6_MOUSE
NC score	0.008008 (rank : 10)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	851	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

CD2L6_HUMAN
NC score	0.008007 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	844	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWU1, Q5JQZ7, Q5JR00, Q8TC78, Q9UPX2	Gene names	CDC2L6, CDK11, KIAA1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11).

CDK8_HUMAN
NC score	0.007614 (rank : 12)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	831	Shared Neighborhood Hits	7
SwissProt Accessions	P49336	Gene names	CDK8
Domain Architecture
Description	Cell division protein kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Protein kinase K35).

CDK7_MOUSE
NC score	0.007601 (rank : 13)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	835	Shared Neighborhood Hits	7
SwissProt Accessions	Q03147, Q99KK3	Gene names	Cdk7, Cdkn7, Crk4, Mo15, Mpk-7
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinase) (CRK4).

CDK7_HUMAN
NC score	0.007565 (rank : 14)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	833	Shared Neighborhood Hits	7
SwissProt Accessions	P50613, Q9BS60, Q9UE19	Gene names	CDK7, MO15
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1).

PGBM_HUMAN
NC score	0.001033 (rank : 15)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	1113	Shared Neighborhood Hits	2
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).