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Network neighborhood for query Sequence : CSN1_HUMAN

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CSN1_HUMAN
SwissProt Accessions	Q13098, Q8NA10, Q9BWL1	Gene names	GPS1, COPS1, CSN1
Domain Architecture
Description	COP9 signalosome complex subunit 1 (Signalosome subunit 1) (SGN1) (JAB1-containing signalosome subunit 1) (G protein pathway suppressor 1) (Protein GPS1) (Protein MFH).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CSN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q13098, Q8NA10, Q9BWL1	Gene names	GPS1, COPS1, CSN1
Domain Architecture
Description	COP9 signalosome complex subunit 1 (Signalosome subunit 1) (SGN1) (JAB1-containing signalosome subunit 1) (G protein pathway suppressor 1) (Protein GPS1) (Protein MFH).

CSN1_MOUSE
θ value	0 (rank : 2)	NC score	0.998720 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q99LD4, Q8C2J7	Gene names	Gps1, Cops1, Csn1
Domain Architecture
Description	COP9 signalosome complex subunit 1 (Signalosome subunit 1) (SGN1) (JAB1-containing signalosome subunit 1) (G protein pathway suppressor 1) (Protein GPS1).

PSMD6_MOUSE
θ value	3.28887e-18 (rank : 3)	NC score	0.619769 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JI4, Q9CWZ1	Gene names	Psmd6
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit S10) (p42A).

PSMD6_HUMAN
θ value	9.56915e-18 (rank : 4)	NC score	0.617498 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q15008	Gene names	PSMD6, KIAA0107, PFAAP4
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit S10) (p42A) (Proteasome regulatory particle subunit p44S10) (Phosphonoformate immuno-associated protein 4) (Breast cancer- associated protein SGA-113M).

CSN2_HUMAN
θ value	0.000121331 (rank : 5)	NC score	0.289959 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	P61201, O88950, Q15647, Q6FGP4, Q9BY54, Q9R249, Q9UNI2, Q9UNQ5	Gene names	COPS2, CSN2, TRIP15
Domain Architecture
Description	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (Alien homolog).

CSN2_MOUSE
θ value	0.000121331 (rank : 6)	NC score	0.289959 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	P61202, O88950, Q15647, Q3V1W6, Q8R5B0, Q9CWU1, Q9R249, Q9UNQ5	Gene names	Cops2, Csn2, Trip15
Domain Architecture
Description	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (Alien homolog).

PSD11_HUMAN
θ value	0.0252991 (rank : 7)	NC score	0.214656 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	O00231, O00495	Gene names	PSMD11
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5).

PSD11_MOUSE
θ value	0.0252991 (rank : 8)	NC score	0.214816 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BG32	Gene names	Psmd11
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5).

CCD16_MOUSE
θ value	0.47712 (rank : 9)	NC score	0.093709 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	218	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1N0, Q3TR52, Q9CWV9, Q9CYI6	Gene names	Ccdc16, Omcg1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16 (Ovus mutant candidate gene 1 protein).

CCD16_HUMAN
θ value	0.62314 (rank : 10)	NC score	0.092554 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

K0841_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.057755 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	O94927, Q6P2P7, Q7L3D5, Q96CT8	Gene names	KIAA0841
Domain Architecture	No domain graphic available
Description	Protein KIAA0841.

MYST4_HUMAN
θ value	2.36792 (rank : 12)	NC score	0.025691 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	671	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

CH016_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.113230 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCU9	Gene names	C8orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C8orf16.

TPM1_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.009643 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	716	Shared Neighborhood Hits	4
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.009555 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	729	Shared Neighborhood Hits	4
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

KRHB2_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.002832 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	233	Shared Neighborhood Hits	2
SwissProt Accessions	Q99M74	Gene names	Krthb2, Krt2-20
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

KRIT1_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.007392 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	258	Shared Neighborhood Hits	2
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

TTC5_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.014673 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N0Z6	Gene names	TTC5
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 5 (TPR repeat protein 5).

Hits sorted by NC score

CSN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q13098, Q8NA10, Q9BWL1	Gene names	GPS1, COPS1, CSN1
Domain Architecture
Description	COP9 signalosome complex subunit 1 (Signalosome subunit 1) (SGN1) (JAB1-containing signalosome subunit 1) (G protein pathway suppressor 1) (Protein GPS1) (Protein MFH).

CSN1_MOUSE
NC score	0.998720 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q99LD4, Q8C2J7	Gene names	Gps1, Cops1, Csn1
Domain Architecture
Description	COP9 signalosome complex subunit 1 (Signalosome subunit 1) (SGN1) (JAB1-containing signalosome subunit 1) (G protein pathway suppressor 1) (Protein GPS1).

PSMD6_MOUSE
NC score	0.619769 (rank : 3)	θ value	3.28887e-18 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JI4, Q9CWZ1	Gene names	Psmd6
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit S10) (p42A).

PSMD6_HUMAN
NC score	0.617498 (rank : 4)	θ value	9.56915e-18 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q15008	Gene names	PSMD6, KIAA0107, PFAAP4
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit S10) (p42A) (Proteasome regulatory particle subunit p44S10) (Phosphonoformate immuno-associated protein 4) (Breast cancer- associated protein SGA-113M).

CSN2_HUMAN
NC score	0.289959 (rank : 5)	θ value	0.000121331 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	P61201, O88950, Q15647, Q6FGP4, Q9BY54, Q9R249, Q9UNI2, Q9UNQ5	Gene names	COPS2, CSN2, TRIP15
Domain Architecture
Description	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (Alien homolog).

CSN2_MOUSE
NC score	0.289959 (rank : 6)	θ value	0.000121331 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	P61202, O88950, Q15647, Q3V1W6, Q8R5B0, Q9CWU1, Q9R249, Q9UNQ5	Gene names	Cops2, Csn2, Trip15
Domain Architecture
Description	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (Alien homolog).

PSD11_MOUSE
NC score	0.214816 (rank : 7)	θ value	0.0252991 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BG32	Gene names	Psmd11
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5).

PSD11_HUMAN
NC score	0.214656 (rank : 8)	θ value	0.0252991 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	O00231, O00495	Gene names	PSMD11
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5).

CH016_HUMAN
NC score	0.113230 (rank : 9)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCU9	Gene names	C8orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C8orf16.

CCD16_MOUSE
NC score	0.093709 (rank : 10)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	218	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1N0, Q3TR52, Q9CWV9, Q9CYI6	Gene names	Ccdc16, Omcg1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16 (Ovus mutant candidate gene 1 protein).

CCD16_HUMAN
NC score	0.092554 (rank : 11)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

K0841_HUMAN
NC score	0.057755 (rank : 12)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	O94927, Q6P2P7, Q7L3D5, Q96CT8	Gene names	KIAA0841
Domain Architecture	No domain graphic available
Description	Protein KIAA0841.

MYST4_HUMAN
NC score	0.025691 (rank : 13)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	671	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

TTC5_HUMAN
NC score	0.014673 (rank : 14)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N0Z6	Gene names	TTC5
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 5 (TPR repeat protein 5).

TPM1_HUMAN
NC score	0.009643 (rank : 15)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	716	Shared Neighborhood Hits	4
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
NC score	0.009555 (rank : 16)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	729	Shared Neighborhood Hits	4
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

KRIT1_HUMAN
NC score	0.007392 (rank : 17)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	258	Shared Neighborhood Hits	2
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRHB2_MOUSE
NC score	0.002832 (rank : 18)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	233	Shared Neighborhood Hits	2
SwissProt Accessions	Q99M74	Gene names	Krthb2, Krt2-20
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).