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Network neighborhood for query Sequence : CREG2_HUMAN

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CREG2_HUMAN
SwissProt Accessions	Q8IUH2, Q86X03, Q8N540, Q8N9E3	Gene names	CREG2
Domain Architecture	No domain graphic available
Description	Protein CREG2 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CREG2_HUMAN
θ value	1.98959e-140 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IUH2, Q86X03, Q8N540, Q8N9E3	Gene names	CREG2
Domain Architecture	No domain graphic available
Description	Protein CREG2 precursor.

CREG2_MOUSE
θ value	2.70151e-121 (rank : 2)	NC score	0.996424 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGC9, Q8BL64, Q8BX89, Q8K049	Gene names	Creg2
Domain Architecture	No domain graphic available
Description	Protein CREG2 precursor.

CREG1_HUMAN
θ value	1.32909e-35 (rank : 3)	NC score	0.895181 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	O75629, Q8N9A3	Gene names	CREG1, CREG
Domain Architecture	No domain graphic available
Description	Protein CREG1 precursor (Cellular repressor of E1A-stimulated genes 1).

CREG1_MOUSE
θ value	1.73584e-35 (rank : 4)	NC score	0.896143 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	O88668, Q3UNP8, Q8C3I1	Gene names	Creg1, Creg
Domain Architecture	No domain graphic available
Description	Protein CREG1 precursor (Cellular repressor of E1A-stimulated genes 1).

IGSF8_HUMAN
θ value	1.81305 (rank : 5)	NC score	0.036349 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q969P0, Q8NG09, Q96DP4, Q9BTG9	Gene names	IGSF8, CD81P3, EWI2, KCT4
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (LIR-D1) (CD316 antigen).

TCF19_HUMAN
θ value	3.0926 (rank : 6)	NC score	0.030508 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	124	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

AIRE_MOUSE
θ value	5.27518 (rank : 7)	NC score	0.014882 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

IGSF8_MOUSE
θ value	6.88961 (rank : 8)	NC score	0.030551 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R366, Q8R0L7	Gene names	Igsf8, Ewi2, Kct4, Pgrl
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (Prostaglandin regulatory- like protein) (CD316 antigen).

DIMT1_MOUSE
θ value	8.99809 (rank : 9)	NC score	0.016761 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D0D4, Q3TTJ5, Q8BVH8	Gene names	Dimt1
Domain Architecture
Description	Probable dimethyladenosine transferase (EC 2.1.1.-) (S- adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) (DIM1 dimethyladenosine transferase 1-like).

HTRA2_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.015607 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HTRA2_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.015628 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

Hits sorted by NC score

CREG2_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.98959e-140 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IUH2, Q86X03, Q8N540, Q8N9E3	Gene names	CREG2
Domain Architecture	No domain graphic available
Description	Protein CREG2 precursor.

CREG2_MOUSE
NC score	0.996424 (rank : 2)	θ value	2.70151e-121 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGC9, Q8BL64, Q8BX89, Q8K049	Gene names	Creg2
Domain Architecture	No domain graphic available
Description	Protein CREG2 precursor.

CREG1_MOUSE
NC score	0.896143 (rank : 3)	θ value	1.73584e-35 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	O88668, Q3UNP8, Q8C3I1	Gene names	Creg1, Creg
Domain Architecture	No domain graphic available
Description	Protein CREG1 precursor (Cellular repressor of E1A-stimulated genes 1).

CREG1_HUMAN
NC score	0.895181 (rank : 4)	θ value	1.32909e-35 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	O75629, Q8N9A3	Gene names	CREG1, CREG
Domain Architecture	No domain graphic available
Description	Protein CREG1 precursor (Cellular repressor of E1A-stimulated genes 1).

IGSF8_HUMAN
NC score	0.036349 (rank : 5)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q969P0, Q8NG09, Q96DP4, Q9BTG9	Gene names	IGSF8, CD81P3, EWI2, KCT4
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (LIR-D1) (CD316 antigen).

IGSF8_MOUSE
NC score	0.030551 (rank : 6)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R366, Q8R0L7	Gene names	Igsf8, Ewi2, Kct4, Pgrl
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (Prostaglandin regulatory- like protein) (CD316 antigen).

TCF19_HUMAN
NC score	0.030508 (rank : 7)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	124	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

DIMT1_MOUSE
NC score	0.016761 (rank : 8)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D0D4, Q3TTJ5, Q8BVH8	Gene names	Dimt1
Domain Architecture
Description	Probable dimethyladenosine transferase (EC 2.1.1.-) (S- adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) (DIM1 dimethyladenosine transferase 1-like).

HTRA2_MOUSE
NC score	0.015628 (rank : 9)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HTRA2_HUMAN
NC score	0.015607 (rank : 10)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

AIRE_MOUSE
NC score	0.014882 (rank : 11)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).