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Network neighborhood for query Sequence : CA048_MOUSE

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CA048_MOUSE
SwissProt Accessions	Q8K305	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf48 homolog.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CA048_MOUSE
θ value	3.38586e-148 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K305	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf48 homolog.

CA048_HUMAN
θ value	2.6227e-108 (rank : 2)	NC score	0.986966 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q96IY1, Q5SY75, Q9H2M5, Q9NRN8, Q9Y415	Gene names	C1orf48
Domain Architecture	No domain graphic available
Description	Protein C1orf48.

NEMO_MOUSE
θ value	0.62314 (rank : 3)	NC score	0.033874 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	658	Shared Neighborhood Hits	6
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

TBC15_MOUSE
θ value	1.81305 (rank : 4)	NC score	0.027533 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CXF4, Q3UI41	Gene names	Tbc1d15
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 15.

BACE1_HUMAN
θ value	2.36792 (rank : 5)	NC score	0.060516 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P56817, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5	Gene names	BACE1, BACE
Domain Architecture
Description	Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).

BACE1_MOUSE
θ value	2.36792 (rank : 6)	NC score	0.060458 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P56818, Q544D0	Gene names	Bace1, Bace
Domain Architecture
Description	Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).

SDCG8_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.013743 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	1002	Shared Neighborhood Hits	6
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

EEA1_MOUSE
θ value	5.27518 (rank : 8)	NC score	0.008285 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	1637	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

NUF2_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.024057 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	585	Shared Neighborhood Hits	7
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

NEMO_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.022676 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	820	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

Hits sorted by NC score

CA048_MOUSE
NC score	0.999962 (rank : 1)	θ value	3.38586e-148 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K305	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf48 homolog.

CA048_HUMAN
NC score	0.986966 (rank : 2)	θ value	2.6227e-108 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q96IY1, Q5SY75, Q9H2M5, Q9NRN8, Q9Y415	Gene names	C1orf48
Domain Architecture	No domain graphic available
Description	Protein C1orf48.

BACE1_HUMAN
NC score	0.060516 (rank : 3)	θ value	2.36792 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P56817, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5	Gene names	BACE1, BACE
Domain Architecture
Description	Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).

BACE1_MOUSE
NC score	0.060458 (rank : 4)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P56818, Q544D0	Gene names	Bace1, Bace
Domain Architecture
Description	Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).

NEMO_MOUSE
NC score	0.033874 (rank : 5)	θ value	0.62314 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	658	Shared Neighborhood Hits	6
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

TBC15_MOUSE
NC score	0.027533 (rank : 6)	θ value	1.81305 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CXF4, Q3UI41	Gene names	Tbc1d15
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 15.

NUF2_MOUSE
NC score	0.024057 (rank : 7)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	585	Shared Neighborhood Hits	7
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

NEMO_HUMAN
NC score	0.022676 (rank : 8)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	820	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

SDCG8_HUMAN
NC score	0.013743 (rank : 9)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	1002	Shared Neighborhood Hits	6
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

EEA1_MOUSE
NC score	0.008285 (rank : 10)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	1637	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.