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Network neighborhood for query Sequence : BL1S2_MOUSE

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BL1S2_MOUSE
SwissProt Accessions	Q9CWG9, Q6P062	Gene names	Bloc1s2, Blos2
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 2 (BLOC subunit 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BL1S2_MOUSE
θ value	6.77864e-56 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CWG9, Q6P062	Gene names	Bloc1s2, Blos2
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 2 (BLOC subunit 2).

BL1S2_HUMAN
θ value	8.02596e-49 (rank : 2)	NC score	0.993852 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q6QNY1, Q5W040, Q8WUI8	Gene names	BLOC1S2, BLOS2, CEAP
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 2 (BLOC subunit 2) (Centrosome-associated protein).

EEA1_MOUSE
θ value	0.0252991 (rank : 3)	NC score	0.060475 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	1637	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

BRE1B_MOUSE
θ value	0.0431538 (rank : 4)	NC score	0.092640 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	970	Shared Neighborhood Hits	15
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
θ value	0.62314 (rank : 5)	NC score	0.079227 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	1040	Shared Neighborhood Hits	15
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

HOOK3_HUMAN
θ value	0.62314 (rank : 6)	NC score	0.058515 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	1070	Shared Neighborhood Hits	16
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

1433B_MOUSE
θ value	0.813845 (rank : 7)	NC score	0.044847 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CQV8, O70455, Q3TY33, Q3UAN6	Gene names	Ywhab
Domain Architecture
Description	14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1).

HOOK3_MOUSE
θ value	1.81305 (rank : 8)	NC score	0.055278 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	1007	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

CTRO_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.017992 (rank : 20)
Query Neighborhood Hits	18	Target Neighborhood Hits	2344	Shared Neighborhood Hits	15
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

1433B_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.033494 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	P31946	Gene names	YWHAB
Domain Architecture
Description	14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1) (Protein 1054).

CROCC_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.040305 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	1409	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.038206 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	1460	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GOGB1_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.032727 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	2297	Shared Neighborhood Hits	15
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

IFT74_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.039181 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	949	Shared Neighborhood Hits	16
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

REST_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.030821 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	1605	Shared Neighborhood Hits	17
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

CF060_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.031806 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	1270	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

MMRN2_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.037515 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	400	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

MYH13_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.025961 (rank : 19)
Query Neighborhood Hits	18	Target Neighborhood Hits	1504	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

BRE1A_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.059045 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	1071	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.059929 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	1025	Shared Neighborhood Hits	14
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

Hits sorted by NC score

BL1S2_MOUSE
NC score	0.999962 (rank : 1)	θ value	6.77864e-56 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CWG9, Q6P062	Gene names	Bloc1s2, Blos2
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 2 (BLOC subunit 2).

BL1S2_HUMAN
NC score	0.993852 (rank : 2)	θ value	8.02596e-49 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q6QNY1, Q5W040, Q8WUI8	Gene names	BLOC1S2, BLOS2, CEAP
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 2 (BLOC subunit 2) (Centrosome-associated protein).

BRE1B_MOUSE
NC score	0.092640 (rank : 3)	θ value	0.0431538 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	970	Shared Neighborhood Hits	15
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
NC score	0.079227 (rank : 4)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	1040	Shared Neighborhood Hits	15
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

EEA1_MOUSE
NC score	0.060475 (rank : 5)	θ value	0.0252991 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	1637	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

BRE1A_MOUSE
NC score	0.059929 (rank : 6)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	18	Target Neighborhood Hits	1025	Shared Neighborhood Hits	14
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BRE1A_HUMAN
NC score	0.059045 (rank : 7)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	18	Target Neighborhood Hits	1071	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

HOOK3_HUMAN
NC score	0.058515 (rank : 8)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	1070	Shared Neighborhood Hits	16
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
NC score	0.055278 (rank : 9)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	1007	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

1433B_MOUSE
NC score	0.044847 (rank : 10)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CQV8, O70455, Q3TY33, Q3UAN6	Gene names	Ywhab
Domain Architecture
Description	14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1).

CROCC_HUMAN
NC score	0.040305 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	1409	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

IFT74_HUMAN
NC score	0.039181 (rank : 12)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	949	Shared Neighborhood Hits	16
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

CROCC_MOUSE
NC score	0.038206 (rank : 13)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	1460	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

MMRN2_HUMAN
NC score	0.037515 (rank : 14)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	400	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

1433B_HUMAN
NC score	0.033494 (rank : 15)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	P31946	Gene names	YWHAB
Domain Architecture
Description	14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1) (Protein 1054).

GOGB1_HUMAN
NC score	0.032727 (rank : 16)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	2297	Shared Neighborhood Hits	15
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CF060_HUMAN
NC score	0.031806 (rank : 17)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	1270	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

REST_HUMAN
NC score	0.030821 (rank : 18)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	1605	Shared Neighborhood Hits	17
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

MYH13_HUMAN
NC score	0.025961 (rank : 19)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	1504	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

CTRO_MOUSE
NC score	0.017992 (rank : 20)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	2344	Shared Neighborhood Hits	15
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).