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Network neighborhood for query Sequence : BL1S2_HUMAN

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BL1S2_HUMAN
SwissProt Accessions	Q6QNY1, Q5W040, Q8WUI8	Gene names	BLOC1S2, BLOS2, CEAP
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 2 (BLOC subunit 2) (Centrosome-associated protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BL1S2_HUMAN
θ value	8.57503e-51 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q6QNY1, Q5W040, Q8WUI8	Gene names	BLOC1S2, BLOS2, CEAP
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 2 (BLOC subunit 2) (Centrosome-associated protein).

BL1S2_MOUSE
θ value	8.02596e-49 (rank : 2)	NC score	0.993852 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CWG9, Q6P062	Gene names	Bloc1s2, Blos2
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 2 (BLOC subunit 2).

EEA1_MOUSE
θ value	0.0431538 (rank : 3)	NC score	0.049326 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	1637	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

BRE1B_MOUSE
θ value	0.47712 (rank : 4)	NC score	0.065810 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	970	Shared Neighborhood Hits	10
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

HOOK3_HUMAN
θ value	0.62314 (rank : 5)	NC score	0.049890 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	1070	Shared Neighborhood Hits	10
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	1.81305 (rank : 6)	NC score	0.046758 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	1007	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

MYH13_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.020350 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	1504	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

B3GN6_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.032537 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BWP8, Q3TY43, Q8BJH9, Q99LW7	Gene names	B3gnt6
Domain Architecture	No domain graphic available
Description	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.149) (Poly-N-acetyllactosamine extension enzyme) (I-beta- 1,3-N-acetylglucosaminyltransferase) (iGnT) (UDP-GlcNAc:betaGal beta- 1,3-N-acetylglucosaminyltransferase 6).

1433B_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.026420 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQV8, O70455, Q3TY33, Q3UAN6	Gene names	Ywhab
Domain Architecture
Description	14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1).

BRE1B_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.052111 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	1040	Shared Neighborhood Hits	9
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

IFT74_HUMAN
θ value	8.99809 (rank : 11)	NC score	0.029203 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	949	Shared Neighborhood Hits	10
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

LAMC1_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.013227 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	856	Shared Neighborhood Hits	8
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

Hits sorted by NC score

BL1S2_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.57503e-51 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q6QNY1, Q5W040, Q8WUI8	Gene names	BLOC1S2, BLOS2, CEAP
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 2 (BLOC subunit 2) (Centrosome-associated protein).

BL1S2_MOUSE
NC score	0.993852 (rank : 2)	θ value	8.02596e-49 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CWG9, Q6P062	Gene names	Bloc1s2, Blos2
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 2 (BLOC subunit 2).

BRE1B_MOUSE
NC score	0.065810 (rank : 3)	θ value	0.47712 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	970	Shared Neighborhood Hits	10
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
NC score	0.052111 (rank : 4)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	1040	Shared Neighborhood Hits	9
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

HOOK3_HUMAN
NC score	0.049890 (rank : 5)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	1070	Shared Neighborhood Hits	10
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

EEA1_MOUSE
NC score	0.049326 (rank : 6)	θ value	0.0431538 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	1637	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

HOOK3_MOUSE
NC score	0.046758 (rank : 7)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	1007	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

B3GN6_MOUSE
NC score	0.032537 (rank : 8)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BWP8, Q3TY43, Q8BJH9, Q99LW7	Gene names	B3gnt6
Domain Architecture	No domain graphic available
Description	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.149) (Poly-N-acetyllactosamine extension enzyme) (I-beta- 1,3-N-acetylglucosaminyltransferase) (iGnT) (UDP-GlcNAc:betaGal beta- 1,3-N-acetylglucosaminyltransferase 6).

IFT74_HUMAN
NC score	0.029203 (rank : 9)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	949	Shared Neighborhood Hits	10
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

1433B_MOUSE
NC score	0.026420 (rank : 10)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQV8, O70455, Q3TY33, Q3UAN6	Gene names	Ywhab
Domain Architecture
Description	14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1).

MYH13_HUMAN
NC score	0.020350 (rank : 11)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	1504	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

LAMC1_MOUSE
NC score	0.013227 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	856	Shared Neighborhood Hits	8
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).