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Network neighborhood for query Sequence : BGH3_HUMAN

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BGH3_HUMAN
SwissProt Accessions	Q15582, O14471, O14472, O14476, O43216, O43217, O43218, O43219	Gene names	TGFBI, BIGH3
Domain Architecture
Description	Transforming growth factor-beta-induced protein ig-h3 precursor (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BGH3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q15582, O14471, O14472, O14476, O43216, O43217, O43218, O43219	Gene names	TGFBI, BIGH3
Domain Architecture
Description	Transforming growth factor-beta-induced protein ig-h3 precursor (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP).

BGH3_MOUSE
θ value	0 (rank : 2)	NC score	0.998858 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	P82198, Q3U9R1	Gene names	Tgfbi
Domain Architecture	No domain graphic available
Description	Transforming growth factor-beta-induced protein ig-h3 precursor (Beta ig-h3).

POSTN_HUMAN
θ value	7.01099e-170 (rank : 3)	NC score	0.971288 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q15063, Q15064, Q5VSY5, Q8IZF9	Gene names	POSTN, OSF2
Domain Architecture
Description	Periostin precursor (PN) (Osteoblast-specific factor 2) (OSF-2).

POSTN_MOUSE
θ value	2.33393e-165 (rank : 4)	NC score	0.970036 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q62009, Q8BMJ6, Q8K1K0	Gene names	Postn, Osf2
Domain Architecture
Description	Periostin precursor (PN) (Osteoblast-specific factor 2) (OSF-2).

STAB2_HUMAN
θ value	1.29331e-14 (rank : 5)	NC score	0.246807 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	534	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
θ value	5.43371e-13 (rank : 6)	NC score	0.242213 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	528	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

STAB1_HUMAN
θ value	2.98157e-11 (rank : 7)	NC score	0.223964 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	546	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	5.08577e-11 (rank : 8)	NC score	0.218720 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	566	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

RPC1_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.045375 (rank : 27)
Query Neighborhood Hits	20	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	O14802, Q8TCW5	Gene names	POLR3A
Domain Architecture
Description	DNA-directed RNA polymerase III largest subunit (EC 2.7.7.6) (RPC155) (RPC1).

FHOD1_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.022989 (rank : 29)
Query Neighborhood Hits	20	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FHOD1_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.021534 (rank : 32)
Query Neighborhood Hits	20	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

AT1A4_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.007380 (rank : 37)
Query Neighborhood Hits	20	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q13733, Q504T2, Q8TBN8, Q8WXA7, Q8WXH7, Q8WY13	Gene names	ATP1A4, ATP1AL2
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-4 chain (EC 3.6.3.9) (Sodium pump 4) (Na+/K+ ATPase 4).

CA103_MOUSE
θ value	5.27518 (rank : 13)	NC score	0.016666 (rank : 33)
Query Neighborhood Hits	20	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CDD9, Q8C893	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf103 homolog.

CNTP1_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.011171 (rank : 36)
Query Neighborhood Hits	20	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

DDX23_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.003804 (rank : 38)
Query Neighborhood Hits	20	Target Neighborhood Hits	486	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

LAX1_MOUSE
θ value	5.27518 (rank : 16)	NC score	0.029997 (rank : 28)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHB3, Q8BS18, Q8CGV1	Gene names	Lax1, Lax
Domain Architecture	No domain graphic available
Description	Lymphocyte transmembrane adapter 1 (Membrane-associated adapter protein LAX) (Linker for activation of X cells).

S27A2_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.011917 (rank : 35)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	O14975	Gene names	SLC27A2, ACSVL1, FACVL1, FATP2, VLACS
Domain Architecture
Description	Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS) (Very-long- chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid- coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid transport protein 2) (FATP-2) (Solute carrier family 27 member 2).

FACD2_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.012781 (rank : 34)
Query Neighborhood Hits	20	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q80V62, Q9CWC7	Gene names	Fancd2
Domain Architecture	No domain graphic available
Description	Fanconi anemia group D2 protein homolog (Protein FACD2).

ANM5_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.022632 (rank : 31)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	O14744, Q6IBR1, Q9UKH1	Gene names	PRMT5, IBP72, JBP1, SKB1
Domain Architecture
Description	Protein arginine N-methyltransferase 5 (EC 2.1.1.125) (EC 2.1.1.-) (Shk1 kinase-binding protein 1 homolog) (SKB1Hs) (Jak-binding protein 1) (72 kDa ICln-binding protein).

ANM5_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.022671 (rank : 30)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIG8, Q3TNN1, Q9QZS9	Gene names	Prmt5, Jbp1, Skb1
Domain Architecture
Description	Protein arginine N-methyltransferase 5 (EC 2.1.1.125) (EC 2.1.1.-) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (Jak-binding protein 1).

CREL1_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.051110 (rank : 24)
Query Neighborhood Hits	20	Target Neighborhood Hits	441	Shared Neighborhood Hits	4
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 22)	NC score	0.050804 (rank : 26)
Query Neighborhood Hits	20	Target Neighborhood Hits	524	Shared Neighborhood Hits	4
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

KR171_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.071458 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR510_HUMAN
θ value	θ > 10 (rank : 24)	NC score	0.056371 (rank : 22)
Query Neighborhood Hits	20	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.062589 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA51_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.059186 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	288	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 27)	NC score	0.060994 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA54_HUMAN
θ value	θ > 10 (rank : 28)	NC score	0.058583 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	270	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 29)	NC score	0.062523 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	257	Shared Neighborhood Hits	4
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.069474 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA58_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.051281 (rank : 23)
Query Neighborhood Hits	20	Target Neighborhood Hits	324	Shared Neighborhood Hits	4
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.051039 (rank : 25)
Query Neighborhood Hits	20	Target Neighborhood Hits	310	Shared Neighborhood Hits	4
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LCE1D_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.066385 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LORI_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.114660 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

TSG6_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.076457 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.075762 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

XLKD1_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.065048 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5Y7, Q8TC18, Q9UNF4	Gene names	XLKD1, CRSBP1, HAR
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Hyaluronic acid receptor) (Extracellular link domain-containing protein 1).

XLKD1_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.063926 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHC0, Q3TUC1, Q99NE4	Gene names	Xlkd1, Crsbp1
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Extracellular link domain-containing protein 1).

Hits sorted by NC score

BGH3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q15582, O14471, O14472, O14476, O43216, O43217, O43218, O43219	Gene names	TGFBI, BIGH3
Domain Architecture
Description	Transforming growth factor-beta-induced protein ig-h3 precursor (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP).

BGH3_MOUSE
NC score	0.998858 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	P82198, Q3U9R1	Gene names	Tgfbi
Domain Architecture	No domain graphic available
Description	Transforming growth factor-beta-induced protein ig-h3 precursor (Beta ig-h3).

POSTN_HUMAN
NC score	0.971288 (rank : 3)	θ value	7.01099e-170 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q15063, Q15064, Q5VSY5, Q8IZF9	Gene names	POSTN, OSF2
Domain Architecture
Description	Periostin precursor (PN) (Osteoblast-specific factor 2) (OSF-2).

POSTN_MOUSE
NC score	0.970036 (rank : 4)	θ value	2.33393e-165 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q62009, Q8BMJ6, Q8K1K0	Gene names	Postn, Osf2
Domain Architecture
Description	Periostin precursor (PN) (Osteoblast-specific factor 2) (OSF-2).

STAB2_HUMAN
NC score	0.246807 (rank : 5)	θ value	1.29331e-14 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	534	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
NC score	0.242213 (rank : 6)	θ value	5.43371e-13 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	528	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

STAB1_HUMAN
NC score	0.223964 (rank : 7)	θ value	2.98157e-11 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	546	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
NC score	0.218720 (rank : 8)	θ value	5.08577e-11 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	566	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

LORI_MOUSE
NC score	0.114660 (rank : 9)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	20	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

TSG6_HUMAN
NC score	0.076457 (rank : 10)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	20	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
NC score	0.075762 (rank : 11)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	20	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

KR171_HUMAN
NC score	0.071458 (rank : 12)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	20	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KRA56_HUMAN
NC score	0.069474 (rank : 13)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	20	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LCE1D_HUMAN
NC score	0.066385 (rank : 14)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	20	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

XLKD1_HUMAN
NC score	0.065048 (rank : 15)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	20	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5Y7, Q8TC18, Q9UNF4	Gene names	XLKD1, CRSBP1, HAR
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Hyaluronic acid receptor) (Extracellular link domain-containing protein 1).

XLKD1_MOUSE
NC score	0.063926 (rank : 16)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	20	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHC0, Q3TUC1, Q99NE4	Gene names	Xlkd1, Crsbp1
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Extracellular link domain-containing protein 1).

KR511_HUMAN
NC score	0.062589 (rank : 17)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	20	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA55_HUMAN
NC score	0.062523 (rank : 18)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	20	Target Neighborhood Hits	257	Shared Neighborhood Hits	4
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA52_HUMAN
NC score	0.060994 (rank : 19)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	20	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA51_HUMAN
NC score	0.059186 (rank : 20)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	20	Target Neighborhood Hits	288	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA54_HUMAN
NC score	0.058583 (rank : 21)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	20	Target Neighborhood Hits	270	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KR510_HUMAN
NC score	0.056371 (rank : 22)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	20	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA58_HUMAN
NC score	0.051281 (rank : 23)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	20	Target Neighborhood Hits	324	Shared Neighborhood Hits	4
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

CREL1_HUMAN
NC score	0.051110 (rank : 24)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	441	Shared Neighborhood Hits	4
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

KRA59_HUMAN
NC score	0.051039 (rank : 25)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	20	Target Neighborhood Hits	310	Shared Neighborhood Hits	4
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

CREL1_MOUSE
NC score	0.050804 (rank : 26)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	20	Target Neighborhood Hits	524	Shared Neighborhood Hits	4
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

RPC1_HUMAN
NC score	0.045375 (rank : 27)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	O14802, Q8TCW5	Gene names	POLR3A
Domain Architecture
Description	DNA-directed RNA polymerase III largest subunit (EC 2.7.7.6) (RPC155) (RPC1).

LAX1_MOUSE
NC score	0.029997 (rank : 28)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHB3, Q8BS18, Q8CGV1	Gene names	Lax1, Lax
Domain Architecture	No domain graphic available
Description	Lymphocyte transmembrane adapter 1 (Membrane-associated adapter protein LAX) (Linker for activation of X cells).

FHOD1_HUMAN
NC score	0.022989 (rank : 29)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

ANM5_MOUSE
NC score	0.022671 (rank : 30)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIG8, Q3TNN1, Q9QZS9	Gene names	Prmt5, Jbp1, Skb1
Domain Architecture
Description	Protein arginine N-methyltransferase 5 (EC 2.1.1.125) (EC 2.1.1.-) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (Jak-binding protein 1).

ANM5_HUMAN
NC score	0.022632 (rank : 31)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	O14744, Q6IBR1, Q9UKH1	Gene names	PRMT5, IBP72, JBP1, SKB1
Domain Architecture
Description	Protein arginine N-methyltransferase 5 (EC 2.1.1.125) (EC 2.1.1.-) (Shk1 kinase-binding protein 1 homolog) (SKB1Hs) (Jak-binding protein 1) (72 kDa ICln-binding protein).

FHOD1_MOUSE
NC score	0.021534 (rank : 32)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

CA103_MOUSE
NC score	0.016666 (rank : 33)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CDD9, Q8C893	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf103 homolog.

FACD2_MOUSE
NC score	0.012781 (rank : 34)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q80V62, Q9CWC7	Gene names	Fancd2
Domain Architecture	No domain graphic available
Description	Fanconi anemia group D2 protein homolog (Protein FACD2).

S27A2_HUMAN
NC score	0.011917 (rank : 35)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	O14975	Gene names	SLC27A2, ACSVL1, FACVL1, FATP2, VLACS
Domain Architecture
Description	Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS) (Very-long- chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid- coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid transport protein 2) (FATP-2) (Solute carrier family 27 member 2).

CNTP1_MOUSE
NC score	0.011171 (rank : 36)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

AT1A4_HUMAN
NC score	0.007380 (rank : 37)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q13733, Q504T2, Q8TBN8, Q8WXA7, Q8WXH7, Q8WY13	Gene names	ATP1A4, ATP1AL2
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-4 chain (EC 3.6.3.9) (Sodium pump 4) (Na+/K+ ATPase 4).

DDX23_HUMAN
NC score	0.003804 (rank : 38)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	486	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).