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Network neighborhood for query Sequence : BCDO1_HUMAN

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BCDO1_HUMAN
SwissProt Accessions	Q9HAY6, Q9NVH5	Gene names	BCMO1, BCDO, BCDO1
Domain Architecture
Description	Beta,beta-carotene 15,15'-monooxygenase (EC 1.14.99.36) (Beta-carotene dioxygenase 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BCDO1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HAY6, Q9NVH5	Gene names	BCMO1, BCDO, BCDO1
Domain Architecture
Description	Beta,beta-carotene 15,15'-monooxygenase (EC 1.14.99.36) (Beta-carotene dioxygenase 1).

BCDO1_MOUSE
θ value	0 (rank : 2)	NC score	0.999063 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJS6, Q6K1L5, Q8C6N5, Q9ERN9	Gene names	Bcmo1, Bcdo, Bcdo1
Domain Architecture
Description	Beta,beta-carotene 15,15'-monooxygenase (EC 1.14.99.36) (Beta-carotene dioxygenase 1).

BCDO2_MOUSE
θ value	9.60843e-119 (rank : 3)	NC score	0.970666 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q99NF1	Gene names	Bcdo2
Domain Architecture
Description	Beta,beta-carotene 9',10'-dioxygenase (EC 1.14.99.-) (Beta-carotene dioxygenase 2) (B-diox-II).

BCDO2_HUMAN
θ value	8.99321e-117 (rank : 4)	NC score	0.968965 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYV7, Q96JC8, Q96JY5	Gene names	BCDO2
Domain Architecture
Description	Beta,beta-carotene 9',10'-dioxygenase (EC 1.14.99.-) (Beta-carotene dioxygenase 2) (B-diox-II).

RPE65_HUMAN
θ value	1.75513e-112 (rank : 5)	NC score	0.965229 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q16518	Gene names	RPE65
Domain Architecture
Description	Retinal pigment epithelium-specific 65 kDa protein.

RPE65_MOUSE
θ value	1.13764e-111 (rank : 6)	NC score	0.964993 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZQ5, Q8VHP2	Gene names	Rpe65
Domain Architecture
Description	Retinal pigment epithelium-specific 65 kDa protein.

ARHGA_HUMAN
θ value	1.06291 (rank : 7)	NC score	0.030490 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

GGA2_HUMAN
θ value	1.38821 (rank : 8)	NC score	0.024768 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

TXNL5_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.046207 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BRA2	Gene names	TXNL5
Domain Architecture	No domain graphic available
Description	Thioredoxin-like protein 5 (14 kDa thioredoxin-related protein) (TRP14) (Protein 42-9-9).

ARHGA_MOUSE
θ value	4.03905 (rank : 10)	NC score	0.027616 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

SRBP1_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.017915 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

AP2C_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.007083 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q92754, O00685, O00730, Q86V30, Q8IVB6, Q9P1X2	Gene names	TFAP2C
Domain Architecture
Description	Transcription factor AP-2 gamma (AP2-gamma) (Activating enhancer- binding protein 2 gamma) (Transcription factor ERF-1).

Hits sorted by NC score

BCDO1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HAY6, Q9NVH5	Gene names	BCMO1, BCDO, BCDO1
Domain Architecture
Description	Beta,beta-carotene 15,15'-monooxygenase (EC 1.14.99.36) (Beta-carotene dioxygenase 1).

BCDO1_MOUSE
NC score	0.999063 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJS6, Q6K1L5, Q8C6N5, Q9ERN9	Gene names	Bcmo1, Bcdo, Bcdo1
Domain Architecture
Description	Beta,beta-carotene 15,15'-monooxygenase (EC 1.14.99.36) (Beta-carotene dioxygenase 1).

BCDO2_MOUSE
NC score	0.970666 (rank : 3)	θ value	9.60843e-119 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q99NF1	Gene names	Bcdo2
Domain Architecture
Description	Beta,beta-carotene 9',10'-dioxygenase (EC 1.14.99.-) (Beta-carotene dioxygenase 2) (B-diox-II).

BCDO2_HUMAN
NC score	0.968965 (rank : 4)	θ value	8.99321e-117 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYV7, Q96JC8, Q96JY5	Gene names	BCDO2
Domain Architecture
Description	Beta,beta-carotene 9',10'-dioxygenase (EC 1.14.99.-) (Beta-carotene dioxygenase 2) (B-diox-II).

RPE65_HUMAN
NC score	0.965229 (rank : 5)	θ value	1.75513e-112 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q16518	Gene names	RPE65
Domain Architecture
Description	Retinal pigment epithelium-specific 65 kDa protein.

RPE65_MOUSE
NC score	0.964993 (rank : 6)	θ value	1.13764e-111 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZQ5, Q8VHP2	Gene names	Rpe65
Domain Architecture
Description	Retinal pigment epithelium-specific 65 kDa protein.

TXNL5_HUMAN
NC score	0.046207 (rank : 7)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BRA2	Gene names	TXNL5
Domain Architecture	No domain graphic available
Description	Thioredoxin-like protein 5 (14 kDa thioredoxin-related protein) (TRP14) (Protein 42-9-9).

ARHGA_HUMAN
NC score	0.030490 (rank : 8)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
NC score	0.027616 (rank : 9)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

GGA2_HUMAN
NC score	0.024768 (rank : 10)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

SRBP1_HUMAN
NC score	0.017915 (rank : 11)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

AP2C_HUMAN
NC score	0.007083 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q92754, O00685, O00730, Q86V30, Q8IVB6, Q9P1X2	Gene names	TFAP2C
Domain Architecture
Description	Transcription factor AP-2 gamma (AP2-gamma) (Activating enhancer- binding protein 2 gamma) (Transcription factor ERF-1).