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Network neighborhood for query Sequence : AP2C_HUMAN

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AP2C_HUMAN
SwissProt Accessions	Q92754, O00685, O00730, Q86V30, Q8IVB6, Q9P1X2	Gene names	TFAP2C
Domain Architecture
Description	Transcription factor AP-2 gamma (AP2-gamma) (Activating enhancer- binding protein 2 gamma) (Transcription factor ERF-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AP2C_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q92754, O00685, O00730, Q86V30, Q8IVB6, Q9P1X2	Gene names	TFAP2C
Domain Architecture
Description	Transcription factor AP-2 gamma (AP2-gamma) (Activating enhancer- binding protein 2 gamma) (Transcription factor ERF-1).

AP2C_MOUSE
θ value	0 (rank : 2)	NC score	0.999241 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q61312	Gene names	Tfap2c, Tcfap2c
Domain Architecture
Description	Transcription factor AP-2 gamma (AP2-gamma) (Activating enhancer- binding protein 2 gamma) (AP-2.2).

AP2A_HUMAN
θ value	1.68428e-139 (rank : 3)	NC score	0.985832 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	P05549, Q13777	Gene names	TFAP2A, AP2TF, TFAP2
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (AP-2 transcription factor) (Activator protein 2) (AP-2).

AP2A_MOUSE
θ value	8.35901e-139 (rank : 4)	NC score	0.986144 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	P34056, Q60740, Q60741, Q60742, Q60743, Q62067, Q62068, Q62069, Q91VX0, Q9CRY4	Gene names	Tfap2a, Ap2tf, Tcfap2a
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (Activator protein 2) (AP-2).

AP2B_HUMAN
θ value	1.69212e-123 (rank : 5)	NC score	0.984153 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_MOUSE
θ value	1.69212e-123 (rank : 6)	NC score	0.984169 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

CRSP2_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.031053 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	380	Shared Neighborhood Hits	3
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

MLL3_MOUSE
θ value	3.0926 (rank : 8)	NC score	0.013203 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	1399	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

CNKR2_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.014302 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.014301 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

GRID1_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.004702 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

PHAR1_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.030750 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0D0, Q3MJ93, Q5JSJ2	Gene names	PHACTR1, KIAA1733, RPEL1
Domain Architecture
Description	Phosphatase and actin regulator 1.

SEM6B_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.005930 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	187	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

BCDO1_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.007083 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAY6, Q9NVH5	Gene names	BCMO1, BCDO, BCDO1
Domain Architecture
Description	Beta,beta-carotene 15,15'-monooxygenase (EC 1.14.99.36) (Beta-carotene dioxygenase 1).

F120C_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.008184 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NX05	Gene names	FAM120C, CXorf17
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C (Tumor antigen BJ-HCC-21).

PHAR1_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.027541 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

Hits sorted by NC score

AP2C_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q92754, O00685, O00730, Q86V30, Q8IVB6, Q9P1X2	Gene names	TFAP2C
Domain Architecture
Description	Transcription factor AP-2 gamma (AP2-gamma) (Activating enhancer- binding protein 2 gamma) (Transcription factor ERF-1).

AP2C_MOUSE
NC score	0.999241 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q61312	Gene names	Tfap2c, Tcfap2c
Domain Architecture
Description	Transcription factor AP-2 gamma (AP2-gamma) (Activating enhancer- binding protein 2 gamma) (AP-2.2).

AP2A_MOUSE
NC score	0.986144 (rank : 3)	θ value	8.35901e-139 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	P34056, Q60740, Q60741, Q60742, Q60743, Q62067, Q62068, Q62069, Q91VX0, Q9CRY4	Gene names	Tfap2a, Ap2tf, Tcfap2a
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (Activator protein 2) (AP-2).

AP2A_HUMAN
NC score	0.985832 (rank : 4)	θ value	1.68428e-139 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	P05549, Q13777	Gene names	TFAP2A, AP2TF, TFAP2
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (AP-2 transcription factor) (Activator protein 2) (AP-2).

AP2B_MOUSE
NC score	0.984169 (rank : 5)	θ value	1.69212e-123 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_HUMAN
NC score	0.984153 (rank : 6)	θ value	1.69212e-123 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

CRSP2_HUMAN
NC score	0.031053 (rank : 7)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	380	Shared Neighborhood Hits	3
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

PHAR1_HUMAN
NC score	0.030750 (rank : 8)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0D0, Q3MJ93, Q5JSJ2	Gene names	PHACTR1, KIAA1733, RPEL1
Domain Architecture
Description	Phosphatase and actin regulator 1.

PHAR1_MOUSE
NC score	0.027541 (rank : 9)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

CNKR2_HUMAN
NC score	0.014302 (rank : 10)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
NC score	0.014301 (rank : 11)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

MLL3_MOUSE
NC score	0.013203 (rank : 12)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	1399	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

F120C_HUMAN
NC score	0.008184 (rank : 13)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NX05	Gene names	FAM120C, CXorf17
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C (Tumor antigen BJ-HCC-21).

BCDO1_HUMAN
NC score	0.007083 (rank : 14)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAY6, Q9NVH5	Gene names	BCMO1, BCDO, BCDO1
Domain Architecture
Description	Beta,beta-carotene 15,15'-monooxygenase (EC 1.14.99.36) (Beta-carotene dioxygenase 1).

SEM6B_HUMAN
NC score	0.005930 (rank : 15)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	187	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

GRID1_MOUSE
NC score	0.004702 (rank : 16)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).