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Network neighborhood for query Sequence : ATG4D_HUMAN

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ATG4D_HUMAN
SwissProt Accessions	Q86TL0	Gene names	ATG4D, APG4D, AUTL4
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4D (EC 3.4.22.-) (Autophagy-related protein 4 homolog D) (Autophagin-4) (Autophagy-related cysteine endopeptidase 4) (AUT-like 4 cysteine endopeptidase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ATG4D_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q86TL0	Gene names	ATG4D, APG4D, AUTL4
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4D (EC 3.4.22.-) (Autophagy-related protein 4 homolog D) (Autophagin-4) (Autophagy-related cysteine endopeptidase 4) (AUT-like 4 cysteine endopeptidase).

ATG4D_MOUSE
θ value	0 (rank : 2)	NC score	0.998312 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGV9, Q8C4N9, Q8K0Q2	Gene names	Atg4d, Apg4d, Autl4
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4D (EC 3.4.22.-) (Autophagy-related protein 4 homolog D) (Autophagin-4) (Autophagy-related cysteine endopeptidase 4) (AUT-like 4 cysteine endopeptidase).

ATG4C_HUMAN
θ value	3.1986e-114 (rank : 3)	NC score	0.976351 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q96DT6, Q96K04	Gene names	ATG4C, APG4C, AUTL3
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4C (EC 3.4.22.-) (Autophagy-related protein 4 homolog C) (Autophagin-3) (Autophagy-related cysteine endopeptidase 3) (AUT-like 3 cysteine endopeptidase).

ATG4C_MOUSE
θ value	2.29227e-112 (rank : 4)	NC score	0.975983 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q811C2, Q6PD25	Gene names	Atg4c, Apg4c, Autl3
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4C (EC 3.4.22.-) (Autophagy-related protein 4 homolog C) (Autophagin-3) (Autophagy-related cysteine endopeptidase 3) (AUT-like 3 cysteine endopeptidase).

ATG4A_MOUSE
θ value	3.48141e-52 (rank : 5)	NC score	0.901311 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C9S8, Q811B8	Gene names	Atg4a, Apg4a, Autl2
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4A (EC 3.4.22.-) (Autophagy-related protein 4 homolog A) (Autophagin-2) (Autophagy-related cysteine endopeptidase 2) (AUT-like 2 cysteine endopeptidase).

ATG4A_HUMAN
θ value	2.49495e-50 (rank : 6)	NC score	0.899249 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WYN0, O95534, Q5JYY9, Q5JYZ0, Q86VE5, Q96KQ0, Q96KQ1	Gene names	ATG4A, APG4A, AUTL2
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4A (EC 3.4.22.-) (Autophagy-related protein 4 homolog A) (hAPG4A) (Autophagin-2) (Autophagy-related cysteine endopeptidase 2) (AUT-like 2 cysteine endopeptidase).

ATG4B_MOUSE
θ value	2.1121e-49 (rank : 7)	NC score	0.896427 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BGE6, Q6ZQ22, Q8R098	Gene names	Atg4b, Apg4b, Autl1, Kiaa0943
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related protein 4 homolog B) (Autophagin-1) (Autophagy-related cysteine endopeptidase 1) (AUT-like 1 cysteine endopeptidase).

ATG4B_HUMAN
θ value	8.02596e-49 (rank : 8)	NC score	0.895216 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4P1, Q6ZUV8, Q8WYM9, Q96K07, Q96K96, Q96SZ1, Q9Y2F2	Gene names	ATG4B, APG4B, AUTL1, KIAA0943
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related protein 4 homolog B) (hAPG4B) (Autophagin-1) (Autophagy-related cysteine endopeptidase 1) (AUT-like 1 cysteine endopeptidase).

LPLC4_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.021065 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P59827, Q5TDX6	Gene names	LPLUNC4, C20orf186
Domain Architecture
Description	Long palate, lung and nasal epithelium carcinoma-associated protein 4 (Ligand-binding protein RY2G5).

ATX2_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.015554 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	445	Shared Neighborhood Hits	3
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

FRS3_MOUSE
θ value	3.0926 (rank : 11)	NC score	0.013995 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	168	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

NUBP2_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.027482 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R061	Gene names	Nubp2
Domain Architecture
Description	Nucleotide-binding protein 2 (NBP 2).

ABTB1_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.005947 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	349	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

DEN1A_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.008585 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

HCN3_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.004902 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

LAP4_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.001946 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	608	Shared Neighborhood Hits	3
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

NR4A1_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.005740 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

OGFR_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.005719 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	584	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

STRC_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.011581 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q7RTU9	Gene names	STRC
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

PIGT_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.010507 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q969N2, Q7Z3N7, Q9BQY7, Q9BQY8, Q9UJG6, Q9Y2Z5	Gene names	PIGT
Domain Architecture
Description	GPI transamidase component PIG-T precursor (Phosphatidylinositol- glycan biosynthesis class T protein).

PTN23_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.003334 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	646	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

Hits sorted by NC score

ATG4D_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q86TL0	Gene names	ATG4D, APG4D, AUTL4
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4D (EC 3.4.22.-) (Autophagy-related protein 4 homolog D) (Autophagin-4) (Autophagy-related cysteine endopeptidase 4) (AUT-like 4 cysteine endopeptidase).

ATG4D_MOUSE
NC score	0.998312 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGV9, Q8C4N9, Q8K0Q2	Gene names	Atg4d, Apg4d, Autl4
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4D (EC 3.4.22.-) (Autophagy-related protein 4 homolog D) (Autophagin-4) (Autophagy-related cysteine endopeptidase 4) (AUT-like 4 cysteine endopeptidase).

ATG4C_HUMAN
NC score	0.976351 (rank : 3)	θ value	3.1986e-114 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q96DT6, Q96K04	Gene names	ATG4C, APG4C, AUTL3
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4C (EC 3.4.22.-) (Autophagy-related protein 4 homolog C) (Autophagin-3) (Autophagy-related cysteine endopeptidase 3) (AUT-like 3 cysteine endopeptidase).

ATG4C_MOUSE
NC score	0.975983 (rank : 4)	θ value	2.29227e-112 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q811C2, Q6PD25	Gene names	Atg4c, Apg4c, Autl3
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4C (EC 3.4.22.-) (Autophagy-related protein 4 homolog C) (Autophagin-3) (Autophagy-related cysteine endopeptidase 3) (AUT-like 3 cysteine endopeptidase).

ATG4A_MOUSE
NC score	0.901311 (rank : 5)	θ value	3.48141e-52 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C9S8, Q811B8	Gene names	Atg4a, Apg4a, Autl2
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4A (EC 3.4.22.-) (Autophagy-related protein 4 homolog A) (Autophagin-2) (Autophagy-related cysteine endopeptidase 2) (AUT-like 2 cysteine endopeptidase).

ATG4A_HUMAN
NC score	0.899249 (rank : 6)	θ value	2.49495e-50 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WYN0, O95534, Q5JYY9, Q5JYZ0, Q86VE5, Q96KQ0, Q96KQ1	Gene names	ATG4A, APG4A, AUTL2
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4A (EC 3.4.22.-) (Autophagy-related protein 4 homolog A) (hAPG4A) (Autophagin-2) (Autophagy-related cysteine endopeptidase 2) (AUT-like 2 cysteine endopeptidase).

ATG4B_MOUSE
NC score	0.896427 (rank : 7)	θ value	2.1121e-49 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BGE6, Q6ZQ22, Q8R098	Gene names	Atg4b, Apg4b, Autl1, Kiaa0943
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related protein 4 homolog B) (Autophagin-1) (Autophagy-related cysteine endopeptidase 1) (AUT-like 1 cysteine endopeptidase).

ATG4B_HUMAN
NC score	0.895216 (rank : 8)	θ value	8.02596e-49 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4P1, Q6ZUV8, Q8WYM9, Q96K07, Q96K96, Q96SZ1, Q9Y2F2	Gene names	ATG4B, APG4B, AUTL1, KIAA0943
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related protein 4 homolog B) (hAPG4B) (Autophagin-1) (Autophagy-related cysteine endopeptidase 1) (AUT-like 1 cysteine endopeptidase).

NUBP2_MOUSE
NC score	0.027482 (rank : 9)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R061	Gene names	Nubp2
Domain Architecture
Description	Nucleotide-binding protein 2 (NBP 2).

LPLC4_HUMAN
NC score	0.021065 (rank : 10)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P59827, Q5TDX6	Gene names	LPLUNC4, C20orf186
Domain Architecture
Description	Long palate, lung and nasal epithelium carcinoma-associated protein 4 (Ligand-binding protein RY2G5).

ATX2_MOUSE
NC score	0.015554 (rank : 11)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	445	Shared Neighborhood Hits	3
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

FRS3_MOUSE
NC score	0.013995 (rank : 12)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	168	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

STRC_HUMAN
NC score	0.011581 (rank : 13)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q7RTU9	Gene names	STRC
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

PIGT_HUMAN
NC score	0.010507 (rank : 14)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q969N2, Q7Z3N7, Q9BQY7, Q9BQY8, Q9UJG6, Q9Y2Z5	Gene names	PIGT
Domain Architecture
Description	GPI transamidase component PIG-T precursor (Phosphatidylinositol- glycan biosynthesis class T protein).

DEN1A_HUMAN
NC score	0.008585 (rank : 15)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

ABTB1_MOUSE
NC score	0.005947 (rank : 16)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	349	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

NR4A1_HUMAN
NC score	0.005740 (rank : 17)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

OGFR_MOUSE
NC score	0.005719 (rank : 18)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	584	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

HCN3_MOUSE
NC score	0.004902 (rank : 19)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

PTN23_HUMAN
NC score	0.003334 (rank : 20)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	646	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

LAP4_HUMAN
NC score	0.001946 (rank : 21)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	608	Shared Neighborhood Hits	3
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).