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Network neighborhood for query Sequence : API5_MOUSE

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API5_MOUSE
SwissProt Accessions	O35841, Q922L2	Gene names	Api5
Domain Architecture	No domain graphic available
Description	Apoptosis inhibitor 5 (API-5) (AAC-11).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

API5_HUMAN
θ value	0 (rank : 1)	NC score	0.999200 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BZZ5, O15441, Q9Y4J7	Gene names	API5
Domain Architecture	No domain graphic available
Description	Apoptosis inhibitor 5 (API-5) (Fibroblast growth factor 2-interacting factor) (FIF) (Protein XAGL) (Antiapoptosis clone 11 protein) (AAC- 11).

API5_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	O35841, Q922L2	Gene names	Api5
Domain Architecture	No domain graphic available
Description	Apoptosis inhibitor 5 (API-5) (AAC-11).

CP46A_HUMAN
θ value	0.279714 (rank : 3)	NC score	0.041867 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6A2	Gene names	CYP46A1, CYP46
Domain Architecture
Description	Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol 24-hydroxylase) (CH24H).

CP46A_MOUSE
θ value	0.813845 (rank : 4)	NC score	0.037439 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVK8	Gene names	Cyp46a1, Cyp46
Domain Architecture
Description	Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol 24-hydroxylase) (CH24H).

AYTL1_HUMAN
θ value	1.06291 (rank : 5)	NC score	0.035528 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	140	Shared Neighborhood Hits	3
SwissProt Accessions	Q7L5N7, Q6MZJ6, Q9NX23	Gene names	AYTL1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1 (EC 2.3.1.-).

IGBP1_MOUSE
θ value	1.81305 (rank : 6)	NC score	0.051367 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q61249	Gene names	Igbp1, Pc52
Domain Architecture
Description	Immunoglobulin-binding protein 1 (CD79a-binding protein 1) (Alpha4 phosphoprotein) (Lymphocyte signal transduction molecule alpha 4) (p52).

PDLI1_MOUSE
θ value	1.81305 (rank : 7)	NC score	0.019782 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	213	Shared Neighborhood Hits	2
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

SPAG6_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.032146 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

CKAP4_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.013459 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	592	Shared Neighborhood Hits	3
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

ULE1B_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.037235 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBT2, O95605, Q9NTJ1, Q9UED2	Gene names	UBLE1B, SAE2, UBA2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

ULE1B_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.035988 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

ANR11_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.004868 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	1289	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CK5P1_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.023458 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTW8, Q9D6Q4	Gene names	Cdk5rap1
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 1 (CDK5 activator-binding protein C42).

MA1A1_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.013530 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P33908, Q9NU44, Q9UJI3	Gene names	MAN1A1
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase).

STK3_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.001552 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	861	Shared Neighborhood Hits	3
SwissProt Accessions	Q13188, Q15445, Q15801, Q96FM6	Gene names	STK3, MST2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1).

STK3_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.001528 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	869	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI10, Q60877, Q80UG4, Q8CI58	Gene names	Stk3, Mess1, Mst2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2).

Hits sorted by NC score

API5_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	O35841, Q922L2	Gene names	Api5
Domain Architecture	No domain graphic available
Description	Apoptosis inhibitor 5 (API-5) (AAC-11).

API5_HUMAN
NC score	0.999200 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BZZ5, O15441, Q9Y4J7	Gene names	API5
Domain Architecture	No domain graphic available
Description	Apoptosis inhibitor 5 (API-5) (Fibroblast growth factor 2-interacting factor) (FIF) (Protein XAGL) (Antiapoptosis clone 11 protein) (AAC- 11).

IGBP1_MOUSE
NC score	0.051367 (rank : 3)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q61249	Gene names	Igbp1, Pc52
Domain Architecture
Description	Immunoglobulin-binding protein 1 (CD79a-binding protein 1) (Alpha4 phosphoprotein) (Lymphocyte signal transduction molecule alpha 4) (p52).

CP46A_HUMAN
NC score	0.041867 (rank : 4)	θ value	0.279714 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6A2	Gene names	CYP46A1, CYP46
Domain Architecture
Description	Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol 24-hydroxylase) (CH24H).

CP46A_MOUSE
NC score	0.037439 (rank : 5)	θ value	0.813845 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVK8	Gene names	Cyp46a1, Cyp46
Domain Architecture
Description	Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol 24-hydroxylase) (CH24H).

ULE1B_HUMAN
NC score	0.037235 (rank : 6)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBT2, O95605, Q9NTJ1, Q9UED2	Gene names	UBLE1B, SAE2, UBA2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

ULE1B_MOUSE
NC score	0.035988 (rank : 7)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

AYTL1_HUMAN
NC score	0.035528 (rank : 8)	θ value	1.06291 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	140	Shared Neighborhood Hits	3
SwissProt Accessions	Q7L5N7, Q6MZJ6, Q9NX23	Gene names	AYTL1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1 (EC 2.3.1.-).

SPAG6_MOUSE
NC score	0.032146 (rank : 9)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

CK5P1_MOUSE
NC score	0.023458 (rank : 10)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTW8, Q9D6Q4	Gene names	Cdk5rap1
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 1 (CDK5 activator-binding protein C42).

PDLI1_MOUSE
NC score	0.019782 (rank : 11)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	213	Shared Neighborhood Hits	2
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

MA1A1_HUMAN
NC score	0.013530 (rank : 12)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P33908, Q9NU44, Q9UJI3	Gene names	MAN1A1
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase).

CKAP4_HUMAN
NC score	0.013459 (rank : 13)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	592	Shared Neighborhood Hits	3
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

ANR11_HUMAN
NC score	0.004868 (rank : 14)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	1289	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

STK3_HUMAN
NC score	0.001552 (rank : 15)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	861	Shared Neighborhood Hits	3
SwissProt Accessions	Q13188, Q15445, Q15801, Q96FM6	Gene names	STK3, MST2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1).

STK3_MOUSE
NC score	0.001528 (rank : 16)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	869	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI10, Q60877, Q80UG4, Q8CI58	Gene names	Stk3, Mess1, Mst2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2).