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Network neighborhood for query Sequence : AGT2_HUMAN

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AGT2_HUMAN
SwissProt Accessions	Q9BYV1, Q53FB4, Q53FY7, Q53G03, Q5W7Q1	Gene names	AGXT2, AGT2
Domain Architecture
Description	Alanine--glyoxylate aminotransferase 2, mitochondrial precursor (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (AGT 2) (Beta-alanine-pyruvate aminotransferase) (Beta- ALAAT II) (D-AIBAT).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AGT2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BYV1, Q53FB4, Q53FY7, Q53G03, Q5W7Q1	Gene names	AGXT2, AGT2
Domain Architecture
Description	Alanine--glyoxylate aminotransferase 2, mitochondrial precursor (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (AGT 2) (Beta-alanine-pyruvate aminotransferase) (Beta- ALAAT II) (D-AIBAT).

OAT_MOUSE
θ value	8.93572e-24 (rank : 2)	NC score	0.713778 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	P29758	Gene names	Oat
Domain Architecture
Description	Ornithine aminotransferase, mitochondrial precursor (EC 2.6.1.13) (Ornithine--oxo-acid aminotransferase).

OAT_HUMAN
θ value	1.6852e-22 (rank : 3)	NC score	0.708783 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	P04181, Q16068, Q16069, Q9UD03	Gene names	OAT
Domain Architecture
Description	Ornithine aminotransferase, mitochondrial precursor (EC 2.6.1.13) (Ornithine--oxo-acid aminotransferase) [Contains: Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, renal form].

GABT_HUMAN
θ value	3.40345e-15 (rank : 4)	NC score	0.591744 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P80404, Q16260, Q8N5W2, Q96BG2, Q99800	Gene names	ABAT, GABAT
Domain Architecture
Description	4-aminobutyrate aminotransferase, mitochondrial precursor (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA aminotransferase) (GABA-AT) (GABA-T) (L-AIBAT).

GABT_MOUSE
θ value	4.91457e-14 (rank : 5)	NC score	0.586737 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	P61922, Q8BZA3	Gene names	Abat, Gabat
Domain Architecture
Description	4-aminobutyrate aminotransferase, mitochondrial precursor (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA aminotransferase) (GABA-AT) (GABA-T) (L-AIBAT).

KR106_HUMAN
θ value	1.06291 (rank : 6)	NC score	0.029053 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	347	Shared Neighborhood Hits	5
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR104_HUMAN
θ value	1.81305 (rank : 7)	NC score	0.027906 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR107_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.026992 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	330	Shared Neighborhood Hits	5
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

3BP2_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.031287 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	296	Shared Neighborhood Hits	3
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ACCN2_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.013734 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P78348, P78349, Q96CV2	Gene names	ACCN2, ASIC1, BNAC2
Domain Architecture
Description	Amiloride-sensitive cation channel 2, neuronal (Acid-sensing ion channel 1) (ASIC1) (Brain sodium channel 2) (BNaC2).

3BP2_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.031451 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

KS6C1_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.005627 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	700	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

LAMC2_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.007817 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	715	Shared Neighborhood Hits	5
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

Hits sorted by NC score

AGT2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BYV1, Q53FB4, Q53FY7, Q53G03, Q5W7Q1	Gene names	AGXT2, AGT2
Domain Architecture
Description	Alanine--glyoxylate aminotransferase 2, mitochondrial precursor (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (AGT 2) (Beta-alanine-pyruvate aminotransferase) (Beta- ALAAT II) (D-AIBAT).

OAT_MOUSE
NC score	0.713778 (rank : 2)	θ value	8.93572e-24 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	P29758	Gene names	Oat
Domain Architecture
Description	Ornithine aminotransferase, mitochondrial precursor (EC 2.6.1.13) (Ornithine--oxo-acid aminotransferase).

OAT_HUMAN
NC score	0.708783 (rank : 3)	θ value	1.6852e-22 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	P04181, Q16068, Q16069, Q9UD03	Gene names	OAT
Domain Architecture
Description	Ornithine aminotransferase, mitochondrial precursor (EC 2.6.1.13) (Ornithine--oxo-acid aminotransferase) [Contains: Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, renal form].

GABT_HUMAN
NC score	0.591744 (rank : 4)	θ value	3.40345e-15 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P80404, Q16260, Q8N5W2, Q96BG2, Q99800	Gene names	ABAT, GABAT
Domain Architecture
Description	4-aminobutyrate aminotransferase, mitochondrial precursor (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA aminotransferase) (GABA-AT) (GABA-T) (L-AIBAT).

GABT_MOUSE
NC score	0.586737 (rank : 5)	θ value	4.91457e-14 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	P61922, Q8BZA3	Gene names	Abat, Gabat
Domain Architecture
Description	4-aminobutyrate aminotransferase, mitochondrial precursor (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA aminotransferase) (GABA-AT) (GABA-T) (L-AIBAT).

3BP2_MOUSE
NC score	0.031451 (rank : 6)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_HUMAN
NC score	0.031287 (rank : 7)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	296	Shared Neighborhood Hits	3
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

KR106_HUMAN
NC score	0.029053 (rank : 8)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	347	Shared Neighborhood Hits	5
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR104_HUMAN
NC score	0.027906 (rank : 9)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR107_HUMAN
NC score	0.026992 (rank : 10)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	330	Shared Neighborhood Hits	5
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

ACCN2_HUMAN
NC score	0.013734 (rank : 11)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P78348, P78349, Q96CV2	Gene names	ACCN2, ASIC1, BNAC2
Domain Architecture
Description	Amiloride-sensitive cation channel 2, neuronal (Acid-sensing ion channel 1) (ASIC1) (Brain sodium channel 2) (BNaC2).

LAMC2_HUMAN
NC score	0.007817 (rank : 12)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	715	Shared Neighborhood Hits	5
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

KS6C1_MOUSE
NC score	0.005627 (rank : 13)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	700	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).