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Network neighborhood for query Sequence : AFAM_HUMAN

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AFAM_HUMAN
SwissProt Accessions	P43652	Gene names	AFM, ALB2, ALBA
Domain Architecture
Description	Afamin precursor (Alpha-albumin) (Alpha-Alb).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AFAM_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P43652	Gene names	AFM, ALB2, ALBA
Domain Architecture
Description	Afamin precursor (Alpha-albumin) (Alpha-Alb).

AFAM_MOUSE
θ value	0 (rank : 2)	NC score	0.995834 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	O89020	Gene names	Afm
Domain Architecture
Description	Afamin precursor (Alpha-albumin) (Alpha-Alb).

FETA_HUMAN
θ value	1.4755e-135 (rank : 3)	NC score	0.976570 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	P02771	Gene names	AFP
Domain Architecture
Description	Alpha-fetoprotein precursor (Alpha-fetoglobulin) (Alpha-1- fetoprotein).

FETA_MOUSE
θ value	6.86991e-125 (rank : 4)	NC score	0.973660 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	P02772, Q3UJD0	Gene names	Afp
Domain Architecture
Description	Alpha-fetoprotein precursor (Alpha-fetoglobulin) (Alpha-1- fetoprotein).

ALBU_HUMAN
θ value	3.77839e-115 (rank : 5)	NC score	0.966726 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P02768, O95574, P04277, Q13140, Q68DN5, Q6UXK4, Q9P157, Q9P1I7, Q9UHS3, Q9UJZ0	Gene names	ALB
Domain Architecture
Description	Serum albumin precursor.

ALBU_MOUSE
θ value	2.6227e-108 (rank : 6)	NC score	0.963966 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	P07724, Q61802	Gene names	Alb, Alb-1, Alb1
Domain Architecture
Description	Serum albumin precursor.

VTDB_MOUSE
θ value	6.38894e-30 (rank : 7)	NC score	0.783086 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P21614, Q7TS97, Q91XG1, Q9CY31	Gene names	Gc
Domain Architecture
Description	Vitamin D-binding protein precursor (DBP) (Group-specific component) (Gc-globulin) (VDB).

VTDB_HUMAN
θ value	8.08199e-25 (rank : 8)	NC score	0.783779 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P02774, Q16309, Q16310	Gene names	GC
Domain Architecture
Description	Vitamin D-binding protein precursor (DBP) (Group-specific component) (Gc-globulin) (VDB).

ADA32_HUMAN
θ value	1.81305 (rank : 9)	NC score	0.007077 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	216	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

IPO4_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.019363 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

ZN644_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.005620 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	704	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H582, Q5TCC0, Q6BEP7, Q6P446, Q6PI06, Q7LG67, Q9ULJ9	Gene names	ZNF644, KIAA1221, ZEP2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2).

FRAP_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.020105 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.020091 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

CASQ1_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.013077 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P31415, Q8TBW7	Gene names	CASQ1, CASQ
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform) (Calmitin).

CF188_MOUSE
θ value	4.03905 (rank : 15)	NC score	0.031534 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R100, Q8C3G8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf188 homolog.

PYGM_MOUSE
θ value	5.27518 (rank : 16)	NC score	0.008263 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUB3	Gene names	Pygm
Domain Architecture
Description	Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase).

UACA_MOUSE
θ value	6.88961 (rank : 17)	NC score	-0.000339 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	1620	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

DYH11_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.005532 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	234	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

Hits sorted by NC score

AFAM_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P43652	Gene names	AFM, ALB2, ALBA
Domain Architecture
Description	Afamin precursor (Alpha-albumin) (Alpha-Alb).

AFAM_MOUSE
NC score	0.995834 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	O89020	Gene names	Afm
Domain Architecture
Description	Afamin precursor (Alpha-albumin) (Alpha-Alb).

FETA_HUMAN
NC score	0.976570 (rank : 3)	θ value	1.4755e-135 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	P02771	Gene names	AFP
Domain Architecture
Description	Alpha-fetoprotein precursor (Alpha-fetoglobulin) (Alpha-1- fetoprotein).

FETA_MOUSE
NC score	0.973660 (rank : 4)	θ value	6.86991e-125 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	P02772, Q3UJD0	Gene names	Afp
Domain Architecture
Description	Alpha-fetoprotein precursor (Alpha-fetoglobulin) (Alpha-1- fetoprotein).

ALBU_HUMAN
NC score	0.966726 (rank : 5)	θ value	3.77839e-115 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P02768, O95574, P04277, Q13140, Q68DN5, Q6UXK4, Q9P157, Q9P1I7, Q9UHS3, Q9UJZ0	Gene names	ALB
Domain Architecture
Description	Serum albumin precursor.

ALBU_MOUSE
NC score	0.963966 (rank : 6)	θ value	2.6227e-108 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	P07724, Q61802	Gene names	Alb, Alb-1, Alb1
Domain Architecture
Description	Serum albumin precursor.

VTDB_HUMAN
NC score	0.783779 (rank : 7)	θ value	8.08199e-25 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P02774, Q16309, Q16310	Gene names	GC
Domain Architecture
Description	Vitamin D-binding protein precursor (DBP) (Group-specific component) (Gc-globulin) (VDB).

VTDB_MOUSE
NC score	0.783086 (rank : 8)	θ value	6.38894e-30 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P21614, Q7TS97, Q91XG1, Q9CY31	Gene names	Gc
Domain Architecture
Description	Vitamin D-binding protein precursor (DBP) (Group-specific component) (Gc-globulin) (VDB).

CF188_MOUSE
NC score	0.031534 (rank : 9)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R100, Q8C3G8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf188 homolog.

FRAP_HUMAN
NC score	0.020105 (rank : 10)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_MOUSE
NC score	0.020091 (rank : 11)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

IPO4_HUMAN
NC score	0.019363 (rank : 12)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

CASQ1_HUMAN
NC score	0.013077 (rank : 13)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P31415, Q8TBW7	Gene names	CASQ1, CASQ
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform) (Calmitin).

PYGM_MOUSE
NC score	0.008263 (rank : 14)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUB3	Gene names	Pygm
Domain Architecture
Description	Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase).

ADA32_HUMAN
NC score	0.007077 (rank : 15)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	216	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ZN644_HUMAN
NC score	0.005620 (rank : 16)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	704	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H582, Q5TCC0, Q6BEP7, Q6P446, Q6PI06, Q7LG67, Q9ULJ9	Gene names	ZNF644, KIAA1221, ZEP2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2).

DYH11_HUMAN
NC score	0.005532 (rank : 17)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	234	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

UACA_MOUSE
NC score	-0.000339 (rank : 18)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	1620	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).