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Network neighborhood for query Sequence : ACY1_HUMAN

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ACY1_HUMAN
SwissProt Accessions	Q03154	Gene names	ACY1
Domain Architecture
Description	Aminoacylase-1 (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) (ACY-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ACY1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	5	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	Q03154	Gene names	ACY1
Domain Architecture
Description	Aminoacylase-1 (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) (ACY-1).

CNDP1_HUMAN
θ value	0.00102713 (rank : 2)	NC score	0.133411 (rank : 2)
Query Neighborhood Hits	5	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KN2, Q2TBG0, Q6UWK2, Q9BT98	Gene names	CNDP1, CN1, CPGL2
Domain Architecture
Description	Beta-Ala-His dipeptidase precursor (EC 3.4.13.20) (Carnosine dipeptidase 1) (CNDP dipeptidase 1) (Serum carnosinase) (Glutamate carboxypeptidase-like protein 2).

BTAF1_HUMAN
θ value	6.88961 (rank : 3)	NC score	0.013234 (rank : 6)
Query Neighborhood Hits	5	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

WNK2_HUMAN
θ value	6.88961 (rank : 4)	NC score	0.004783 (rank : 8)
Query Neighborhood Hits	5	Target Neighborhood Hits	1407	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ATP7A_MOUSE
θ value	8.99809 (rank : 5)	NC score	0.012668 (rank : 7)
Query Neighborhood Hits	5	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	Q64430, O35101, P97422, Q64431	Gene names	Atp7a, Mnk
Domain Architecture
Description	Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkes disease-associated protein homolog).

CNDP2_HUMAN
θ value	θ > 10 (rank : 7)	NC score	0.056836 (rank : 5)
Query Neighborhood Hits	5	Target Neighborhood Hits	8	Shared Neighborhood Hits	1
SwissProt Accessions	Q96KP4, Q9BQ94, Q9NVB4	Gene names	CNDP2, CN2, CPGL
Domain Architecture
Description	Cytosolic nonspecific dipeptidase (Glutamate carboxypeptidase-like protein 1) (CNDP dipeptidase 2).

CNDP2_MOUSE
θ value	θ > 10 (rank : 8)	NC score	0.057041 (rank : 4)
Query Neighborhood Hits	5	Target Neighborhood Hits	9	Shared Neighborhood Hits	1
SwissProt Accessions	Q9D1A2, Q3TI32, Q99PV1	Gene names	Cndp2, Cn2
Domain Architecture
Description	Cytosolic nonspecific dipeptidase (Glutamate carboxypeptidase-like protein 1) (CNDP dipeptidase 2).

Hits sorted by NC score

ACY1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	5	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	Q03154	Gene names	ACY1
Domain Architecture
Description	Aminoacylase-1 (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) (ACY-1).

CNDP1_HUMAN
NC score	0.133411 (rank : 2)	θ value	0.00102713 (rank : 2)
Query Neighborhood Hits	5	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KN2, Q2TBG0, Q6UWK2, Q9BT98	Gene names	CNDP1, CN1, CPGL2
Domain Architecture
Description	Beta-Ala-His dipeptidase precursor (EC 3.4.13.20) (Carnosine dipeptidase 1) (CNDP dipeptidase 1) (Serum carnosinase) (Glutamate carboxypeptidase-like protein 2).

CNDP2_MOUSE
NC score	0.057041 (rank : 4)	θ value	θ > 10 (rank : 8)
Query Neighborhood Hits	5	Target Neighborhood Hits	9	Shared Neighborhood Hits	1
SwissProt Accessions	Q9D1A2, Q3TI32, Q99PV1	Gene names	Cndp2, Cn2
Domain Architecture
Description	Cytosolic nonspecific dipeptidase (Glutamate carboxypeptidase-like protein 1) (CNDP dipeptidase 2).

CNDP2_HUMAN
NC score	0.056836 (rank : 5)	θ value	θ > 10 (rank : 7)
Query Neighborhood Hits	5	Target Neighborhood Hits	8	Shared Neighborhood Hits	1
SwissProt Accessions	Q96KP4, Q9BQ94, Q9NVB4	Gene names	CNDP2, CN2, CPGL
Domain Architecture
Description	Cytosolic nonspecific dipeptidase (Glutamate carboxypeptidase-like protein 1) (CNDP dipeptidase 2).

BTAF1_HUMAN
NC score	0.013234 (rank : 6)	θ value	6.88961 (rank : 3)
Query Neighborhood Hits	5	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

ATP7A_MOUSE
NC score	0.012668 (rank : 7)	θ value	8.99809 (rank : 5)
Query Neighborhood Hits	5	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	Q64430, O35101, P97422, Q64431	Gene names	Atp7a, Mnk
Domain Architecture
Description	Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkes disease-associated protein homolog).

WNK2_HUMAN
NC score	0.004783 (rank : 8)	θ value	6.88961 (rank : 4)
Query Neighborhood Hits	5	Target Neighborhood Hits	1407	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).