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Network neighborhood for query Sequence : TSSP_HUMAN

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TSSP_HUMAN
SwissProt Accessions	Q9NQE7, O75416	Gene names	PRSS16, TSSP
Domain Architecture
Description	Thymus-specific serine protease precursor (EC 3.4.-.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TSSP_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQE7, O75416	Gene names	PRSS16, TSSP
Domain Architecture
Description	Thymus-specific serine protease precursor (EC 3.4.-.-).

TSSP_MOUSE
θ value	0 (rank : 2)	NC score	0.997246 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QXE5	Gene names	Prss16, Tssp
Domain Architecture
Description	Thymus-specific serine protease precursor (EC 3.4.-.-).

DPP2_HUMAN
θ value	3.86705e-35 (rank : 3)	NC score	0.811707 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHL4, Q969X4	Gene names	DPP7, DPP2, QPP
Domain Architecture
Description	Dipeptidyl-peptidase 2 precursor (EC 3.4.14.2) (Dipeptidyl-peptidase II) (DPP II) (Dipeptidyl aminopeptidase II) (Quiescent cell proline dipeptidase) (Dipeptidyl peptidase 7).

DPP2_MOUSE
θ value	6.82597e-32 (rank : 4)	NC score	0.807892 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ET22	Gene names	Dpp7, Dpp2, Qpp
Domain Architecture
Description	Dipeptidyl-peptidase 2 precursor (EC 3.4.14.2) (Dipeptidyl-peptidase II) (DPP II) (Dipeptidyl aminopeptidase II) (Quiescent cell proline dipeptidase) (Dipeptidyl peptidase 7).

PCP_HUMAN
θ value	9.8567e-31 (rank : 5)	NC score	0.787950 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P42785	Gene names	PRCP, PCP
Domain Architecture
Description	Lysosomal Pro-X carboxypeptidase precursor (EC 3.4.16.2) (Prolylcarboxypeptidase) (PRCP) (Proline carboxypeptidase) (Angiotensinase C) (Lysosomal carboxypeptidase C).

PCP_MOUSE
θ value	2.51237e-26 (rank : 6)	NC score	0.776514 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TMR0, Q3V302, Q8BKK3, Q8R0T8	Gene names	Prcp
Domain Architecture	No domain graphic available
Description	Lysosomal Pro-X carboxypeptidase precursor (EC 3.4.16.2) (Prolylcarboxypeptidase) (PRCP) (Proline carboxypeptidase).

ATS3_HUMAN
θ value	1.81305 (rank : 7)	NC score	0.009370 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	179	Shared Neighborhood Hits	2
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

SL9A7_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.019407 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q96T83, O75827, Q5JXP9	Gene names	SLC9A7, NHE7
Domain Architecture
Description	Sodium/hydrogen exchanger 7 (Na(+)/H(+) exchanger 7) (NHE-7) (Solute carrier family 9 member 7).

SL9A7_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.019548 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BLV3	Gene names	Slc9a7, Nhe7
Domain Architecture
Description	Sodium/hydrogen exchanger 7 (Na(+)/H(+) exchanger 7) (NHE-7) (Solute carrier family 9 member 7).

PEX5R_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.021457 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C437, Q8CA31, Q9DAA1, Q9JMB9	Gene names	Pex5l, Pex2, Pex5r, Pxr2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

ZDHC1_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.012924 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

CROP_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.014620 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	402	Shared Neighborhood Hits	3
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

CROP_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.014661 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	403	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

NFKB2_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.005136 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	325	Shared Neighborhood Hits	2
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

PEX5R_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.020213 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYB4, Q9NQD1, Q9P2U3, Q9P2U4	Gene names	PEX5L, PEX5R, PXR2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

GGA2_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.008124 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	114	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

HV3Q_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.002918 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	P01778	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region ZAP.

Hits sorted by NC score

TSSP_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQE7, O75416	Gene names	PRSS16, TSSP
Domain Architecture
Description	Thymus-specific serine protease precursor (EC 3.4.-.-).

TSSP_MOUSE
NC score	0.997246 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QXE5	Gene names	Prss16, Tssp
Domain Architecture
Description	Thymus-specific serine protease precursor (EC 3.4.-.-).

DPP2_HUMAN
NC score	0.811707 (rank : 3)	θ value	3.86705e-35 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHL4, Q969X4	Gene names	DPP7, DPP2, QPP
Domain Architecture
Description	Dipeptidyl-peptidase 2 precursor (EC 3.4.14.2) (Dipeptidyl-peptidase II) (DPP II) (Dipeptidyl aminopeptidase II) (Quiescent cell proline dipeptidase) (Dipeptidyl peptidase 7).

DPP2_MOUSE
NC score	0.807892 (rank : 4)	θ value	6.82597e-32 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ET22	Gene names	Dpp7, Dpp2, Qpp
Domain Architecture
Description	Dipeptidyl-peptidase 2 precursor (EC 3.4.14.2) (Dipeptidyl-peptidase II) (DPP II) (Dipeptidyl aminopeptidase II) (Quiescent cell proline dipeptidase) (Dipeptidyl peptidase 7).

PCP_HUMAN
NC score	0.787950 (rank : 5)	θ value	9.8567e-31 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P42785	Gene names	PRCP, PCP
Domain Architecture
Description	Lysosomal Pro-X carboxypeptidase precursor (EC 3.4.16.2) (Prolylcarboxypeptidase) (PRCP) (Proline carboxypeptidase) (Angiotensinase C) (Lysosomal carboxypeptidase C).

PCP_MOUSE
NC score	0.776514 (rank : 6)	θ value	2.51237e-26 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TMR0, Q3V302, Q8BKK3, Q8R0T8	Gene names	Prcp
Domain Architecture	No domain graphic available
Description	Lysosomal Pro-X carboxypeptidase precursor (EC 3.4.16.2) (Prolylcarboxypeptidase) (PRCP) (Proline carboxypeptidase).

PEX5R_MOUSE
NC score	0.021457 (rank : 7)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C437, Q8CA31, Q9DAA1, Q9JMB9	Gene names	Pex5l, Pex2, Pex5r, Pxr2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

PEX5R_HUMAN
NC score	0.020213 (rank : 8)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYB4, Q9NQD1, Q9P2U3, Q9P2U4	Gene names	PEX5L, PEX5R, PXR2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

SL9A7_MOUSE
NC score	0.019548 (rank : 9)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BLV3	Gene names	Slc9a7, Nhe7
Domain Architecture
Description	Sodium/hydrogen exchanger 7 (Na(+)/H(+) exchanger 7) (NHE-7) (Solute carrier family 9 member 7).

SL9A7_HUMAN
NC score	0.019407 (rank : 10)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q96T83, O75827, Q5JXP9	Gene names	SLC9A7, NHE7
Domain Architecture
Description	Sodium/hydrogen exchanger 7 (Na(+)/H(+) exchanger 7) (NHE-7) (Solute carrier family 9 member 7).

CROP_MOUSE
NC score	0.014661 (rank : 11)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	403	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

CROP_HUMAN
NC score	0.014620 (rank : 12)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	402	Shared Neighborhood Hits	3
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

ZDHC1_HUMAN
NC score	0.012924 (rank : 13)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

ATS3_HUMAN
NC score	0.009370 (rank : 14)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	179	Shared Neighborhood Hits	2
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

GGA2_HUMAN
NC score	0.008124 (rank : 15)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	114	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

NFKB2_HUMAN
NC score	0.005136 (rank : 16)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	325	Shared Neighborhood Hits	2
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

HV3Q_HUMAN
NC score	0.002918 (rank : 17)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	P01778	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region ZAP.