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Network neighborhood for query Sequence : TIMP2_HUMAN

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TIMP2_HUMAN
SwissProt Accessions	P16035, Q16121, Q93006, Q9UDF7	Gene names	TIMP2
Domain Architecture
Description	Metalloproteinase inhibitor 2 precursor (TIMP-2) (Tissue inhibitor of metalloproteinases 2) (CSC-21K).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TIMP2_HUMAN
θ value	1.93603e-119 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P16035, Q16121, Q93006, Q9UDF7	Gene names	TIMP2
Domain Architecture
Description	Metalloproteinase inhibitor 2 precursor (TIMP-2) (Tissue inhibitor of metalloproteinases 2) (CSC-21K).

TIMP2_MOUSE
θ value	6.228e-118 (rank : 2)	NC score	0.999780 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P25785	Gene names	Timp2, Timp-2
Domain Architecture
Description	Metalloproteinase inhibitor 2 precursor (TIMP-2) (Tissue inhibitor of metalloproteinases 2).

TIMP4_HUMAN
θ value	1.61343e-57 (rank : 3)	NC score	0.975055 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q99727	Gene names	TIMP4
Domain Architecture
Description	Metalloproteinase inhibitor 4 precursor (TIMP-4) (Tissue inhibitor of metalloproteinases 4).

TIMP4_MOUSE
θ value	3.974e-56 (rank : 4)	NC score	0.974490 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JHB3, Q924B7	Gene names	Timp4
Domain Architecture
Description	Metalloproteinase inhibitor 4 precursor (TIMP-4) (Tissue inhibitor of metalloproteinases 4).

TIMP3_HUMAN
θ value	3.2585e-50 (rank : 5)	NC score	0.963610 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P35625, Q5THV4, Q9UC74, Q9UGS2	Gene names	TIMP3
Domain Architecture
Description	Metalloproteinase inhibitor 3 precursor (TIMP-3) (Tissue inhibitor of metalloproteinases 3) (Protein MIG-5).

TIMP3_MOUSE
θ value	2.75849e-49 (rank : 6)	NC score	0.962566 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P39876, Q91WL9	Gene names	Timp3, Sun, Timp-3
Domain Architecture
Description	Metalloproteinase inhibitor 3 precursor (TIMP-3) (Tissue inhibitor of metalloproteinases 3).

TIMP1_HUMAN
θ value	1.32909e-35 (rank : 7)	NC score	0.937480 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P01033, Q14252, Q9UCU1	Gene names	TIMP1, CLGI, TIMP
Domain Architecture
Description	Metalloproteinase inhibitor 1 precursor (TIMP-1) (Erythroid potentiating activity) (EPA) (Tissue inhibitor of metalloproteinases) (Fibroblast collagenase inhibitor) (Collagenase inhibitor).

TIMP1_MOUSE
θ value	1.6813e-30 (rank : 8)	NC score	0.928663 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P12032, P20064, Q61720	Gene names	Timp1, Timp, Timp-1
Domain Architecture
Description	Metalloproteinase inhibitor 1 precursor (TIMP-1) (Erythroid potentiating activity) (EPA) (Tissue inhibitor of metalloproteinases) (Collagenase inhibitor 16C8 fibroblast) (TPA-induced protein) (TPA- S1).

ABL1_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.002095 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	1220	Shared Neighborhood Hits	4
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.002093 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	1178	Shared Neighborhood Hits	4
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

GP176_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.003362 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	539	Shared Neighborhood Hits	2
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

K0427_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.014895 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PEE2	Gene names	Gm672
Domain Architecture	No domain graphic available
Description	Protein KIAA0427 homolog.

Hits sorted by NC score

TIMP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.93603e-119 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P16035, Q16121, Q93006, Q9UDF7	Gene names	TIMP2
Domain Architecture
Description	Metalloproteinase inhibitor 2 precursor (TIMP-2) (Tissue inhibitor of metalloproteinases 2) (CSC-21K).

TIMP2_MOUSE
NC score	0.999780 (rank : 2)	θ value	6.228e-118 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P25785	Gene names	Timp2, Timp-2
Domain Architecture
Description	Metalloproteinase inhibitor 2 precursor (TIMP-2) (Tissue inhibitor of metalloproteinases 2).

TIMP4_HUMAN
NC score	0.975055 (rank : 3)	θ value	1.61343e-57 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q99727	Gene names	TIMP4
Domain Architecture
Description	Metalloproteinase inhibitor 4 precursor (TIMP-4) (Tissue inhibitor of metalloproteinases 4).

TIMP4_MOUSE
NC score	0.974490 (rank : 4)	θ value	3.974e-56 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JHB3, Q924B7	Gene names	Timp4
Domain Architecture
Description	Metalloproteinase inhibitor 4 precursor (TIMP-4) (Tissue inhibitor of metalloproteinases 4).

TIMP3_HUMAN
NC score	0.963610 (rank : 5)	θ value	3.2585e-50 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P35625, Q5THV4, Q9UC74, Q9UGS2	Gene names	TIMP3
Domain Architecture
Description	Metalloproteinase inhibitor 3 precursor (TIMP-3) (Tissue inhibitor of metalloproteinases 3) (Protein MIG-5).

TIMP3_MOUSE
NC score	0.962566 (rank : 6)	θ value	2.75849e-49 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P39876, Q91WL9	Gene names	Timp3, Sun, Timp-3
Domain Architecture
Description	Metalloproteinase inhibitor 3 precursor (TIMP-3) (Tissue inhibitor of metalloproteinases 3).

TIMP1_HUMAN
NC score	0.937480 (rank : 7)	θ value	1.32909e-35 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P01033, Q14252, Q9UCU1	Gene names	TIMP1, CLGI, TIMP
Domain Architecture
Description	Metalloproteinase inhibitor 1 precursor (TIMP-1) (Erythroid potentiating activity) (EPA) (Tissue inhibitor of metalloproteinases) (Fibroblast collagenase inhibitor) (Collagenase inhibitor).

TIMP1_MOUSE
NC score	0.928663 (rank : 8)	θ value	1.6813e-30 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P12032, P20064, Q61720	Gene names	Timp1, Timp, Timp-1
Domain Architecture
Description	Metalloproteinase inhibitor 1 precursor (TIMP-1) (Erythroid potentiating activity) (EPA) (Tissue inhibitor of metalloproteinases) (Collagenase inhibitor 16C8 fibroblast) (TPA-induced protein) (TPA- S1).

K0427_MOUSE
NC score	0.014895 (rank : 9)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PEE2	Gene names	Gm672
Domain Architecture	No domain graphic available
Description	Protein KIAA0427 homolog.

GP176_MOUSE
NC score	0.003362 (rank : 10)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	539	Shared Neighborhood Hits	2
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

ABL1_HUMAN
NC score	0.002095 (rank : 11)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	1220	Shared Neighborhood Hits	4
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
NC score	0.002093 (rank : 12)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	1178	Shared Neighborhood Hits	4
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).