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Network neighborhood for query Sequence : TBCA_HUMAN

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TBCA_HUMAN
SwissProt Accessions	O75347	Gene names	TBCA
Domain Architecture
Description	Tubulin-specific chaperone A (Tubulin-folding cofactor A) (CFA) (TCP1- chaperonin cofactor A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TBCA_HUMAN
θ value	2.12192e-33 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	O75347	Gene names	TBCA
Domain Architecture
Description	Tubulin-specific chaperone A (Tubulin-folding cofactor A) (CFA) (TCP1- chaperonin cofactor A).

TBCA_MOUSE
θ value	4.89182e-30 (rank : 2)	NC score	0.983751 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P48428	Gene names	Tbca
Domain Architecture
Description	Tubulin-specific chaperone A (Tubulin-folding cofactor A) (CFA) (TCP1- chaperonin cofactor A).

GOGB1_HUMAN
θ value	0.125558 (rank : 3)	NC score	0.050490 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	2297	Shared Neighborhood Hits	15
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HAP1_HUMAN
θ value	0.279714 (rank : 4)	NC score	0.088900 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	606	Shared Neighborhood Hits	13
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

STMN1_HUMAN
θ value	1.38821 (rank : 5)	NC score	0.064169 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	554	Shared Neighborhood Hits	7
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

STMN1_MOUSE
θ value	1.81305 (rank : 6)	NC score	0.062455 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	560	Shared Neighborhood Hits	7
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

BICD1_HUMAN
θ value	2.36792 (rank : 7)	NC score	0.040610 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	844	Shared Neighborhood Hits	12
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

RAD50_MOUSE
θ value	2.36792 (rank : 8)	NC score	0.040264 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	1366	Shared Neighborhood Hits	12
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

HOME2_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.032273 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	882	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

RAD50_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.041259 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	1317	Shared Neighborhood Hits	12
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

EP15R_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.037404 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	1083	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.037666 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

K1C12_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.014110 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	372	Shared Neighborhood Hits	12
SwissProt Accessions	Q99456	Gene names	KRT12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

BEGIN_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.029405 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	454	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

KIF5C_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.022325 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	1040	Shared Neighborhood Hits	14
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

HAP1_MOUSE
θ value	θ > 10 (rank : 16)	NC score	0.056321 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	388	Shared Neighborhood Hits	7
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

Hits sorted by NC score

TBCA_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.12192e-33 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	O75347	Gene names	TBCA
Domain Architecture
Description	Tubulin-specific chaperone A (Tubulin-folding cofactor A) (CFA) (TCP1- chaperonin cofactor A).

TBCA_MOUSE
NC score	0.983751 (rank : 2)	θ value	4.89182e-30 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P48428	Gene names	Tbca
Domain Architecture
Description	Tubulin-specific chaperone A (Tubulin-folding cofactor A) (CFA) (TCP1- chaperonin cofactor A).

HAP1_HUMAN
NC score	0.088900 (rank : 3)	θ value	0.279714 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	606	Shared Neighborhood Hits	13
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

STMN1_HUMAN
NC score	0.064169 (rank : 4)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	554	Shared Neighborhood Hits	7
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

STMN1_MOUSE
NC score	0.062455 (rank : 5)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	560	Shared Neighborhood Hits	7
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

HAP1_MOUSE
NC score	0.056321 (rank : 6)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	388	Shared Neighborhood Hits	7
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

GOGB1_HUMAN
NC score	0.050490 (rank : 7)	θ value	0.125558 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	2297	Shared Neighborhood Hits	15
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

RAD50_HUMAN
NC score	0.041259 (rank : 8)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	1317	Shared Neighborhood Hits	12
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

BICD1_HUMAN
NC score	0.040610 (rank : 9)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	844	Shared Neighborhood Hits	12
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

RAD50_MOUSE
NC score	0.040264 (rank : 10)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	1366	Shared Neighborhood Hits	12
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

EP15R_MOUSE
NC score	0.037666 (rank : 11)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15R_HUMAN
NC score	0.037404 (rank : 12)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	1083	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

HOME2_MOUSE
NC score	0.032273 (rank : 13)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	882	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

BEGIN_HUMAN
NC score	0.029405 (rank : 14)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	454	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

KIF5C_MOUSE
NC score	0.022325 (rank : 15)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	1040	Shared Neighborhood Hits	14
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

K1C12_HUMAN
NC score	0.014110 (rank : 16)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	372	Shared Neighborhood Hits	12
SwissProt Accessions	Q99456	Gene names	KRT12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).