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Network neighborhood for query Sequence : SHH_HUMAN

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SHH_HUMAN
SwissProt Accessions	Q15465, Q75MC9	Gene names	SHH
Domain Architecture
Description	Sonic hedgehog protein precursor (SHH) (HHG-1) [Contains: Sonic hedgehog protein N-product; Sonic hedgehog protein C-product].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SHH_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q15465, Q75MC9	Gene names	SHH
Domain Architecture
Description	Sonic hedgehog protein precursor (SHH) (HHG-1) [Contains: Sonic hedgehog protein N-product; Sonic hedgehog protein C-product].

SHH_MOUSE
θ value	0 (rank : 2)	NC score	0.999707 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q62226	Gene names	Shh, Hhg1
Domain Architecture
Description	Sonic hedgehog protein precursor (SHH) (HHG-1) [Contains: Sonic hedgehog protein N-product; Sonic hedgehog protein C-product].

IHH_MOUSE
θ value	7.33985e-127 (rank : 3)	NC score	0.989462 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	P97812, Q61724	Gene names	Ihh
Domain Architecture
Description	Indian hedgehog protein precursor (IHH) (HHG-2) [Contains: Indian hedgehog protein N-product; Indian hedgehog protein C-product].

IHH_HUMAN
θ value	2.20997e-123 (rank : 4)	NC score	0.988990 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q14623, O43322, Q8N4B9	Gene names	IHH
Domain Architecture
Description	Indian hedgehog protein precursor (IHH) (HHG-2) [Contains: Indian hedgehog protein N-product; Indian hedgehog protein C-product].

DHH_MOUSE
θ value	2.37213e-109 (rank : 5)	NC score	0.987721 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q61488	Gene names	Dhh
Domain Architecture
Description	Desert hedgehog protein precursor (DHH) (HHG-3) [Contains: Desert hedgehog protein N-product; Desert hedgehog protein C-product].

DHH_HUMAN
θ value	5.28454e-109 (rank : 6)	NC score	0.987705 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	O43323, Q15794	Gene names	DHH
Domain Architecture
Description	Desert hedgehog protein precursor (DHH) (HHG-3) [Contains: Desert hedgehog protein N-product; Desert hedgehog protein C-product].

ZBTB3_MOUSE
θ value	1.81305 (rank : 7)	NC score	0.004664 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	792	Shared Neighborhood Hits	2
SwissProt Accessions	Q91X45, Q8BIJ4	Gene names	Zbtb3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

RALY_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.021715 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKM9, Q14621, Q5QPL8, Q9BQX6, Q9UJE3	Gene names	RALY, P542
Domain Architecture
Description	RNA-binding protein Raly (hnRNP associated with lethal yellow homolog) (Autoantigen p542).

RALY_MOUSE
θ value	6.88961 (rank : 9)	NC score	0.019876 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	141	Shared Neighborhood Hits	4
SwissProt Accessions	Q64012, Q99K76, Q9CXH8, Q9QZX6	Gene names	Raly, Merc
Domain Architecture
Description	RNA-binding protein Raly (hnRNP associated with lethal yellow protein) (Maternally expressed hnRNP C-related protein).

PAPPA_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.006041 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

Hits sorted by NC score

SHH_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q15465, Q75MC9	Gene names	SHH
Domain Architecture
Description	Sonic hedgehog protein precursor (SHH) (HHG-1) [Contains: Sonic hedgehog protein N-product; Sonic hedgehog protein C-product].

SHH_MOUSE
NC score	0.999707 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q62226	Gene names	Shh, Hhg1
Domain Architecture
Description	Sonic hedgehog protein precursor (SHH) (HHG-1) [Contains: Sonic hedgehog protein N-product; Sonic hedgehog protein C-product].

IHH_MOUSE
NC score	0.989462 (rank : 3)	θ value	7.33985e-127 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	P97812, Q61724	Gene names	Ihh
Domain Architecture
Description	Indian hedgehog protein precursor (IHH) (HHG-2) [Contains: Indian hedgehog protein N-product; Indian hedgehog protein C-product].

IHH_HUMAN
NC score	0.988990 (rank : 4)	θ value	2.20997e-123 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q14623, O43322, Q8N4B9	Gene names	IHH
Domain Architecture
Description	Indian hedgehog protein precursor (IHH) (HHG-2) [Contains: Indian hedgehog protein N-product; Indian hedgehog protein C-product].

DHH_MOUSE
NC score	0.987721 (rank : 5)	θ value	2.37213e-109 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q61488	Gene names	Dhh
Domain Architecture
Description	Desert hedgehog protein precursor (DHH) (HHG-3) [Contains: Desert hedgehog protein N-product; Desert hedgehog protein C-product].

DHH_HUMAN
NC score	0.987705 (rank : 6)	θ value	5.28454e-109 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	O43323, Q15794	Gene names	DHH
Domain Architecture
Description	Desert hedgehog protein precursor (DHH) (HHG-3) [Contains: Desert hedgehog protein N-product; Desert hedgehog protein C-product].

RALY_HUMAN
NC score	0.021715 (rank : 7)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKM9, Q14621, Q5QPL8, Q9BQX6, Q9UJE3	Gene names	RALY, P542
Domain Architecture
Description	RNA-binding protein Raly (hnRNP associated with lethal yellow homolog) (Autoantigen p542).

RALY_MOUSE
NC score	0.019876 (rank : 8)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	141	Shared Neighborhood Hits	4
SwissProt Accessions	Q64012, Q99K76, Q9CXH8, Q9QZX6	Gene names	Raly, Merc
Domain Architecture
Description	RNA-binding protein Raly (hnRNP associated with lethal yellow protein) (Maternally expressed hnRNP C-related protein).

PAPPA_HUMAN
NC score	0.006041 (rank : 9)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

ZBTB3_MOUSE
NC score	0.004664 (rank : 10)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	792	Shared Neighborhood Hits	2
SwissProt Accessions	Q91X45, Q8BIJ4	Gene names	Zbtb3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.