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Network neighborhood for query Sequence : SEP10_HUMAN

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SEP10_HUMAN
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SEP10_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	161
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.

SEP10_MOUSE
θ value	0 (rank : 2)	NC score	0.994087 (rank : 2)
Query Neighborhood Hits	161	Target Neighborhood Hits	145	Shared Neighborhood Hits	94
SwissProt Accessions	Q8C650, Q7TSA5	Gene names	Sept10
Domain Architecture	No domain graphic available
Description	Septin-10.

SEP11_MOUSE
θ value	4.6918e-174 (rank : 3)	NC score	0.968512 (rank : 7)
Query Neighborhood Hits	161	Target Neighborhood Hits	300	Shared Neighborhood Hits	73
SwissProt Accessions	Q8C1B7, Q6P2K5, Q6P6I0	Gene names	Sept11, D5Ertd606e
Domain Architecture	No domain graphic available
Description	Septin-11.

SEP11_HUMAN
θ value	8.84838e-173 (rank : 4)	NC score	0.969359 (rank : 6)
Query Neighborhood Hits	161	Target Neighborhood Hits	296	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NVA2, Q7L4N1	Gene names	SEPT11
Domain Architecture	No domain graphic available
Description	Septin-11.

SEPT6_HUMAN
θ value	2.17943e-171 (rank : 5)	NC score	0.980370 (rank : 3)
Query Neighborhood Hits	161	Target Neighborhood Hits	220	Shared Neighborhood Hits	60
SwissProt Accessions	Q14141, Q5JTK0, Q969W5, Q96A13, Q96GR1, Q96P86, Q96P87	Gene names	SEPT6, KIAA0128, SEP2
Domain Architecture
Description	Septin-6.

SEPT6_MOUSE
θ value	4.11024e-170 (rank : 6)	NC score	0.978646 (rank : 4)
Query Neighborhood Hits	161	Target Neighborhood Hits	244	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R1T4, Q91XH2, Q9CZ94	Gene names	Sept6
Domain Architecture
Description	Septin-6.

SEPT8_HUMAN
θ value	5.93515e-169 (rank : 7)	NC score	0.968060 (rank : 8)
Query Neighborhood Hits	161	Target Neighborhood Hits	290	Shared Neighborhood Hits	70
SwissProt Accessions	Q92599, Q8IX36, Q8IX37, Q9BVB3	Gene names	SEPT8, KIAA0202
Domain Architecture
Description	Septin-8.

SEPT8_MOUSE
θ value	4.25343e-167 (rank : 8)	NC score	0.973393 (rank : 5)
Query Neighborhood Hits	161	Target Neighborhood Hits	251	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CHH9, Q80YC7, Q9ESF7	Gene names	Sept8, Kiaa0202
Domain Architecture
Description	Septin-8.

SEPT7_HUMAN
θ value	6.73165e-80 (rank : 9)	NC score	0.934331 (rank : 19)
Query Neighborhood Hits	161	Target Neighborhood Hits	385	Shared Neighborhood Hits	100
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SEPT7_MOUSE
θ value	6.73165e-80 (rank : 10)	NC score	0.933239 (rank : 20)
Query Neighborhood Hits	161	Target Neighborhood Hits	327	Shared Neighborhood Hits	78
SwissProt Accessions	O55131	Gene names	Sept7, Cdc10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SEPT3_HUMAN
θ value	1.71981e-67 (rank : 11)	NC score	0.957619 (rank : 9)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UH03, Q6IBZ6, Q8N3P3	Gene names	SEPT3, SEP3
Domain Architecture
Description	Neuronal-specific septin-3.

SEPT4_MOUSE
θ value	2.24614e-67 (rank : 12)	NC score	0.946237 (rank : 17)
Query Neighborhood Hits	161	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	P28661, Q5ND15	Gene names	Sept4, Pnutl2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5).

SEPT5_HUMAN
θ value	3.83135e-67 (rank : 13)	NC score	0.949677 (rank : 14)
Query Neighborhood Hits	161	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q99719, O15251	Gene names	SEPT5, PNUTL1
Domain Architecture
Description	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1).

SEPT5_MOUSE
θ value	5.00389e-67 (rank : 14)	NC score	0.950280 (rank : 13)
Query Neighborhood Hits	161	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z2Q6, Q3UYG4, Q6PB74	Gene names	Sept5, Pnutl1
Domain Architecture	No domain graphic available
Description	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1).

SEPT4_HUMAN
θ value	8.53533e-67 (rank : 15)	NC score	0.945508 (rank : 18)
Query Neighborhood Hits	161	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	O43236, Q9UM58	Gene names	SEPT4, PNUTL2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5) (Cell division control-related protein 2) (hCDCREL-2) (Bradeion beta) (CE5B3 beta) (Cerebral protein 7).

SEPT9_HUMAN
θ value	2.74572e-65 (rank : 16)	NC score	0.866314 (rank : 22)
Query Neighborhood Hits	161	Target Neighborhood Hits	706	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SEPT9_MOUSE
θ value	6.11685e-65 (rank : 17)	NC score	0.923650 (rank : 21)
Query Neighborhood Hits	161	Target Neighborhood Hits	238	Shared Neighborhood Hits	29
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SEPT1_HUMAN
θ value	3.03575e-64 (rank : 18)	NC score	0.949332 (rank : 15)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WYJ6, Q8NEZ1, Q96EL4, Q9H285	Gene names	SEPT1, PNUTL3
Domain Architecture
Description	Septin-1 (LARP) (Serologically defined breast cancer antigen NY-BR- 24).

SEPT2_MOUSE
θ value	3.03575e-64 (rank : 19)	NC score	0.950456 (rank : 12)
Query Neighborhood Hits	161	Target Neighborhood Hits	105	Shared Neighborhood Hits	34
SwissProt Accessions	P42208, Q3U9Y5	Gene names	Sept2, Nedd-5, Nedd5
Domain Architecture
Description	Septin-2 (Protein NEDD5) (Neural precursor cell expressed developmentally down-regulated protein 5).

SEPT2_HUMAN
θ value	3.96481e-64 (rank : 20)	NC score	0.950935 (rank : 11)
Query Neighborhood Hits	161	Target Neighborhood Hits	101	Shared Neighborhood Hits	35
SwissProt Accessions	Q15019, Q14132, Q8IUK9, Q96CB0	Gene names	SEPT2, DIFF6, KIAA0158, NEDD5
Domain Architecture
Description	Septin-2 (Protein NEDD5).

SEPT3_MOUSE
θ value	5.7252e-63 (rank : 21)	NC score	0.953259 (rank : 10)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1S5	Gene names	Sept3, Sep3
Domain Architecture
Description	Neuronal-specific septin-3.

SEPT1_MOUSE
θ value	1.19377e-60 (rank : 22)	NC score	0.948750 (rank : 16)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	P42209	Gene names	Sept1, Diff6, Pnutl3
Domain Architecture
Description	Septin-1 (Differentiation protein 6) (Diff6 protein).

GRAP1_MOUSE
θ value	0.0330416 (rank : 23)	NC score	0.064627 (rank : 31)
Query Neighborhood Hits	161	Target Neighborhood Hits	1234	Shared Neighborhood Hits	114
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

SWP70_MOUSE
θ value	0.0330416 (rank : 24)	NC score	0.084451 (rank : 23)
Query Neighborhood Hits	161	Target Neighborhood Hits	1097	Shared Neighborhood Hits	110
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

GRAP1_HUMAN
θ value	0.0563607 (rank : 25)	NC score	0.050967 (rank : 75)
Query Neighborhood Hits	161	Target Neighborhood Hits	944	Shared Neighborhood Hits	97
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

CTRO_MOUSE
θ value	0.0736092 (rank : 26)	NC score	0.036302 (rank : 125)
Query Neighborhood Hits	161	Target Neighborhood Hits	2344	Shared Neighborhood Hits	114
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

SYCP1_MOUSE
θ value	0.0961366 (rank : 27)	NC score	0.061420 (rank : 39)
Query Neighborhood Hits	161	Target Neighborhood Hits	1456	Shared Neighborhood Hits	111
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

LIPA1_HUMAN
θ value	0.125558 (rank : 28)	NC score	0.063057 (rank : 35)
Query Neighborhood Hits	161	Target Neighborhood Hits	1294	Shared Neighborhood Hits	118
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

RBCC1_MOUSE
θ value	0.163984 (rank : 29)	NC score	0.080636 (rank : 26)
Query Neighborhood Hits	161	Target Neighborhood Hits	1048	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

CAPS2_HUMAN
θ value	0.279714 (rank : 30)	NC score	0.029783 (rank : 137)
Query Neighborhood Hits	161	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8	Gene names	CADPS2, CAPS2, KIAA1591
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

LMNB1_MOUSE
θ value	0.279714 (rank : 31)	NC score	0.036592 (rank : 123)
Query Neighborhood Hits	161	Target Neighborhood Hits	719	Shared Neighborhood Hits	84
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

WBP11_HUMAN
θ value	0.279714 (rank : 32)	NC score	0.080779 (rank : 25)
Query Neighborhood Hits	161	Target Neighborhood Hits	354	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	0.279714 (rank : 33)	NC score	0.082068 (rank : 24)
Query Neighborhood Hits	161	Target Neighborhood Hits	362	Shared Neighborhood Hits	25
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

GOGA4_HUMAN
θ value	0.365318 (rank : 34)	NC score	0.061225 (rank : 40)
Query Neighborhood Hits	161	Target Neighborhood Hits	2034	Shared Neighborhood Hits	118
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RRBP1_MOUSE
θ value	0.365318 (rank : 35)	NC score	0.056569 (rank : 53)
Query Neighborhood Hits	161	Target Neighborhood Hits	1650	Shared Neighborhood Hits	111
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

LMNB1_HUMAN
θ value	0.47712 (rank : 36)	NC score	0.034502 (rank : 128)
Query Neighborhood Hits	161	Target Neighborhood Hits	714	Shared Neighborhood Hits	83
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

PEPL_MOUSE
θ value	0.47712 (rank : 37)	NC score	0.042807 (rank : 102)
Query Neighborhood Hits	161	Target Neighborhood Hits	1105	Shared Neighborhood Hits	104
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PKHG1_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.028218 (rank : 140)
Query Neighborhood Hits	161	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

U2AFM_HUMAN
θ value	0.47712 (rank : 39)	NC score	0.052864 (rank : 67)
Query Neighborhood Hits	161	Target Neighborhood Hits	577	Shared Neighborhood Hits	76
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

CAPS2_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.028922 (rank : 139)
Query Neighborhood Hits	161	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BYR5, O08903, Q66JM7, Q6PCL7, Q76I88, Q7TMM6, Q80ZV8, Q8BL25, Q8BY04, Q8K3K6	Gene names	Cadps2, Caps2
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

LRSM1_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.034410 (rank : 129)
Query Neighborhood Hits	161	Target Neighborhood Hits	1078	Shared Neighborhood Hits	97
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MINK1_HUMAN
θ value	0.62314 (rank : 42)	NC score	0.007662 (rank : 178)
Query Neighborhood Hits	161	Target Neighborhood Hits	1477	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	0.62314 (rank : 43)	NC score	0.007681 (rank : 177)
Query Neighborhood Hits	161	Target Neighborhood Hits	1451	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

BEGIN_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.048546 (rank : 82)
Query Neighborhood Hits	161	Target Neighborhood Hits	454	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

CP250_MOUSE
θ value	0.813845 (rank : 45)	NC score	0.048563 (rank : 81)
Query Neighborhood Hits	161	Target Neighborhood Hits	1583	Shared Neighborhood Hits	113
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

LIPA2_HUMAN
θ value	0.813845 (rank : 46)	NC score	0.048756 (rank : 79)
Query Neighborhood Hits	161	Target Neighborhood Hits	1044	Shared Neighborhood Hits	96
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MYH9_MOUSE
θ value	0.813845 (rank : 47)	NC score	0.045556 (rank : 91)
Query Neighborhood Hits	161	Target Neighborhood Hits	1829	Shared Neighborhood Hits	117
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SWP70_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.060146 (rank : 41)
Query Neighborhood Hits	161	Target Neighborhood Hits	973	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

ZN291_HUMAN
θ value	0.813845 (rank : 49)	NC score	0.045842 (rank : 89)
Query Neighborhood Hits	161	Target Neighborhood Hits	647	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

GOGB1_HUMAN
θ value	1.06291 (rank : 50)	NC score	0.058728 (rank : 44)
Query Neighborhood Hits	161	Target Neighborhood Hits	2297	Shared Neighborhood Hits	118
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

INCE_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.048611 (rank : 80)
Query Neighborhood Hits	161	Target Neighborhood Hits	978	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

KMHN1_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.038468 (rank : 116)
Query Neighborhood Hits	161	Target Neighborhood Hits	950	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

TACC3_MOUSE
θ value	1.06291 (rank : 53)	NC score	0.042890 (rank : 101)
Query Neighborhood Hits	161	Target Neighborhood Hits	607	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

BPAEA_MOUSE
θ value	1.38821 (rank : 54)	NC score	0.041530 (rank : 105)
Query Neighborhood Hits	161	Target Neighborhood Hits	1480	Shared Neighborhood Hits	107
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD39_HUMAN
θ value	1.38821 (rank : 55)	NC score	0.045702 (rank : 90)
Query Neighborhood Hits	161	Target Neighborhood Hits	868	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

MEFV_HUMAN
θ value	1.38821 (rank : 56)	NC score	0.011122 (rank : 169)
Query Neighborhood Hits	161	Target Neighborhood Hits	431	Shared Neighborhood Hits	45
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

OXR1_MOUSE
θ value	1.38821 (rank : 57)	NC score	0.017850 (rank : 157)
Query Neighborhood Hits	161	Target Neighborhood Hits	516	Shared Neighborhood Hits	36
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PCNT_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.049590 (rank : 77)
Query Neighborhood Hits	161	Target Neighborhood Hits	1207	Shared Neighborhood Hits	105
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PLEC1_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.033913 (rank : 131)
Query Neighborhood Hits	161	Target Neighborhood Hits	1326	Shared Neighborhood Hits	94
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RN168_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.019897 (rank : 154)
Query Neighborhood Hits	161	Target Neighborhood Hits	370	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRHY_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.039934 (rank : 110)
Query Neighborhood Hits	161	Target Neighborhood Hits	1385	Shared Neighborhood Hits	95
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

BICD1_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.049035 (rank : 78)
Query Neighborhood Hits	161	Target Neighborhood Hits	844	Shared Neighborhood Hits	94
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD1_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.058319 (rank : 45)
Query Neighborhood Hits	161	Target Neighborhood Hits	837	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CAF1A_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.038781 (rank : 114)
Query Neighborhood Hits	161	Target Neighborhood Hits	736	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CECR2_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.013461 (rank : 164)
Query Neighborhood Hits	161	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

FYB_MOUSE
θ value	1.81305 (rank : 66)	NC score	0.018106 (rank : 156)
Query Neighborhood Hits	161	Target Neighborhood Hits	194	Shared Neighborhood Hits	8
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GBP1_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.024880 (rank : 144)
Query Neighborhood Hits	161	Target Neighborhood Hits	339	Shared Neighborhood Hits	61
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

IF3A_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.040464 (rank : 108)
Query Neighborhood Hits	161	Target Neighborhood Hits	871	Shared Neighborhood Hits	97
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

ITSN1_MOUSE
θ value	1.81305 (rank : 69)	NC score	0.041839 (rank : 104)
Query Neighborhood Hits	161	Target Neighborhood Hits	1669	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MYO5A_MOUSE
θ value	1.81305 (rank : 70)	NC score	0.027838 (rank : 141)
Query Neighborhood Hits	161	Target Neighborhood Hits	1117	Shared Neighborhood Hits	104
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

RABE1_MOUSE
θ value	1.81305 (rank : 71)	NC score	0.046940 (rank : 86)
Query Neighborhood Hits	161	Target Neighborhood Hits	1105	Shared Neighborhood Hits	104
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

SKIL_MOUSE
θ value	1.81305 (rank : 72)	NC score	0.067677 (rank : 30)
Query Neighborhood Hits	161	Target Neighborhood Hits	719	Shared Neighborhood Hits	87
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

TCRG1_HUMAN
θ value	1.81305 (rank : 73)	NC score	0.054092 (rank : 61)
Query Neighborhood Hits	161	Target Neighborhood Hits	929	Shared Neighborhood Hits	93
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	1.81305 (rank : 74)	NC score	0.056169 (rank : 54)
Query Neighborhood Hits	161	Target Neighborhood Hits	947	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TF2H1_HUMAN
θ value	1.81305 (rank : 75)	NC score	0.025835 (rank : 143)
Query Neighborhood Hits	161	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P32780, Q9H5K5, Q9NQD9	Gene names	GTF2H1, BTF2
Domain Architecture
Description	TFIIH basal transcription factor complex p62 subunit (Basic transcription factor 62 kDa subunit) (BTF2-p62) (General transcription factor IIH polypeptide 1).

TF2H1_MOUSE
θ value	1.81305 (rank : 76)	NC score	0.025839 (rank : 142)
Query Neighborhood Hits	161	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBA9, O35637	Gene names	Gtf2h1
Domain Architecture
Description	TFIIH basal transcription factor complex p62 subunit (Basic transcription factor 62 kDa subunit) (BTF2-p62) (General transcription factor IIH polypeptide 1).

BEGIN_MOUSE
θ value	2.36792 (rank : 77)	NC score	0.041438 (rank : 106)
Query Neighborhood Hits	161	Target Neighborhood Hits	383	Shared Neighborhood Hits	59
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

IF3A_HUMAN
θ value	2.36792 (rank : 78)	NC score	0.040175 (rank : 109)
Query Neighborhood Hits	161	Target Neighborhood Hits	875	Shared Neighborhood Hits	98
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

MRCKB_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.023399 (rank : 148)
Query Neighborhood Hits	161	Target Neighborhood Hits	2239	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RB6I2_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.046497 (rank : 88)
Query Neighborhood Hits	161	Target Neighborhood Hits	1584	Shared Neighborhood Hits	115
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	2.36792 (rank : 81)	NC score	0.044493 (rank : 97)
Query Neighborhood Hits	161	Target Neighborhood Hits	1433	Shared Neighborhood Hits	111
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

TRI32_MOUSE
θ value	2.36792 (rank : 82)	NC score	0.010653 (rank : 174)
Query Neighborhood Hits	161	Target Neighborhood Hits	271	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

U2AFM_MOUSE
θ value	2.36792 (rank : 83)	NC score	0.045025 (rank : 93)
Query Neighborhood Hits	161	Target Neighborhood Hits	543	Shared Neighborhood Hits	68
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

BICD2_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.053706 (rank : 63)
Query Neighborhood Hits	161	Target Neighborhood Hits	856	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.057898 (rank : 47)
Query Neighborhood Hits	161	Target Neighborhood Hits	864	Shared Neighborhood Hits	94
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

GBP2_MOUSE
θ value	3.0926 (rank : 86)	NC score	0.029043 (rank : 138)
Query Neighborhood Hits	161	Target Neighborhood Hits	323	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z0E6, Q8CIC6, Q921N2, Q9R1I0	Gene names	Gbp2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (mGBP2) (mGBP-2).

HIP1R_MOUSE
θ value	3.0926 (rank : 87)	NC score	0.045420 (rank : 92)
Query Neighborhood Hits	161	Target Neighborhood Hits	959	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

IF2P_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.034369 (rank : 130)
Query Neighborhood Hits	161	Target Neighborhood Hits	889	Shared Neighborhood Hits	74
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MICA1_MOUSE
θ value	3.0926 (rank : 89)	NC score	0.021759 (rank : 151)
Query Neighborhood Hits	161	Target Neighborhood Hits	400	Shared Neighborhood Hits	58
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

PININ_MOUSE
θ value	3.0926 (rank : 90)	NC score	0.035446 (rank : 127)
Query Neighborhood Hits	161	Target Neighborhood Hits	777	Shared Neighborhood Hits	85
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RAB15_HUMAN
θ value	3.0926 (rank : 91)	NC score	0.013916 (rank : 163)
Query Neighborhood Hits	161	Target Neighborhood Hits	283	Shared Neighborhood Hits	18
SwissProt Accessions	P59190, Q86TX7, Q8IW89	Gene names	RAB15
Domain Architecture
Description	Ras-related protein Rab-15.

RNF8_MOUSE
θ value	3.0926 (rank : 92)	NC score	0.024161 (rank : 146)
Query Neighborhood Hits	161	Target Neighborhood Hits	618	Shared Neighborhood Hits	71
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

SM1L2_MOUSE
θ value	3.0926 (rank : 93)	NC score	0.033629 (rank : 132)
Query Neighborhood Hits	161	Target Neighborhood Hits	918	Shared Neighborhood Hits	93
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

U2AFL_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.044681 (rank : 94)
Query Neighborhood Hits	161	Target Neighborhood Hits	503	Shared Neighborhood Hits	69
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

CING_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.052532 (rank : 69)
Query Neighborhood Hits	161	Target Neighborhood Hits	1275	Shared Neighborhood Hits	109
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

DBP_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.011745 (rank : 168)
Query Neighborhood Hits	161	Target Neighborhood Hits	137	Shared Neighborhood Hits	11
SwissProt Accessions	Q60925, Q8VCX3	Gene names	Dbp
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein).

DESP_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.055654 (rank : 56)
Query Neighborhood Hits	161	Target Neighborhood Hits	1470	Shared Neighborhood Hits	117
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DMD_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.041368 (rank : 107)
Query Neighborhood Hits	161	Target Neighborhood Hits	1135	Shared Neighborhood Hits	107
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

LIPA3_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.037912 (rank : 119)
Query Neighborhood Hits	161	Target Neighborhood Hits	828	Shared Neighborhood Hits	85
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPA3_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.037673 (rank : 121)
Query Neighborhood Hits	161	Target Neighborhood Hits	636	Shared Neighborhood Hits	75
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MAT1_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.021775 (rank : 150)
Query Neighborhood Hits	161	Target Neighborhood Hits	217	Shared Neighborhood Hits	33
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MYH9_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.044079 (rank : 99)
Query Neighborhood Hits	161	Target Neighborhood Hits	1762	Shared Neighborhood Hits	117
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RAB10_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.010765 (rank : 171)
Query Neighborhood Hits	161	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	P61026, O88386, Q6IA52, Q9D7X6, Q9H0T3	Gene names	RAB10
Domain Architecture
Description	Ras-related protein Rab-10.

RAB10_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.010765 (rank : 172)
Query Neighborhood Hits	161	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	P61027, O88386, Q9D7X6	Gene names	Rab10
Domain Architecture
Description	Ras-related protein Rab-10.

VP13A_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.036158 (rank : 126)
Query Neighborhood Hits	161	Target Neighborhood Hits	93	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

BRE1A_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.031878 (rank : 135)
Query Neighborhood Hits	161	Target Neighborhood Hits	1025	Shared Neighborhood Hits	82
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CCD91_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.063359 (rank : 33)
Query Neighborhood Hits	161	Target Neighborhood Hits	868	Shared Neighborhood Hits	104
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CD2L1_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.002846 (rank : 185)
Query Neighborhood Hits	161	Target Neighborhood Hits	1463	Shared Neighborhood Hits	61
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CENPF_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.063153 (rank : 34)
Query Neighborhood Hits	161	Target Neighborhood Hits	1932	Shared Neighborhood Hits	112
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CTGE5_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.044462 (rank : 98)
Query Neighborhood Hits	161	Target Neighborhood Hits	800	Shared Neighborhood Hits	86
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

DBP_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.010936 (rank : 170)
Query Neighborhood Hits	161	Target Neighborhood Hits	136	Shared Neighborhood Hits	11
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

FYB_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.013372 (rank : 165)
Query Neighborhood Hits	161	Target Neighborhood Hits	379	Shared Neighborhood Hits	12
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GCC2_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.044615 (rank : 96)
Query Neighborhood Hits	161	Target Neighborhood Hits	1558	Shared Neighborhood Hits	110
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GCP60_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.031685 (rank : 136)
Query Neighborhood Hits	161	Target Neighborhood Hits	419	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GOGA6_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.046587 (rank : 87)
Query Neighborhood Hits	161	Target Neighborhood Hits	1007	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

MAT1_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.020631 (rank : 152)
Query Neighborhood Hits	161	Target Neighborhood Hits	179	Shared Neighborhood Hits	30
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MYO5B_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.022677 (rank : 149)
Query Neighborhood Hits	161	Target Neighborhood Hits	911	Shared Neighborhood Hits	97
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

NIN_MOUSE
θ value	5.27518 (rank : 118)	NC score	0.039446 (rank : 111)
Query Neighborhood Hits	161	Target Neighborhood Hits	1376	Shared Neighborhood Hits	110
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NUCB2_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.038394 (rank : 117)
Query Neighborhood Hits	161	Target Neighborhood Hits	459	Shared Neighborhood Hits	72
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

RBP24_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.044633 (rank : 95)
Query Neighborhood Hits	161	Target Neighborhood Hits	1559	Shared Neighborhood Hits	109
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

UBXD8_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.016622 (rank : 158)
Query Neighborhood Hits	161	Target Neighborhood Hits	131	Shared Neighborhood Hits	20
SwissProt Accessions	Q96CS3, O94963, Q8IUF2, Q9BRP2, Q9BVM7	Gene names	UBXD8, ETEA, KIAA0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8 (Protein ETEA).

AKAP9_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.047266 (rank : 85)
Query Neighborhood Hits	161	Target Neighborhood Hits	1710	Shared Neighborhood Hits	116
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

BRD3_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.010264 (rank : 175)
Query Neighborhood Hits	161	Target Neighborhood Hits	402	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

CN145_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.038972 (rank : 113)
Query Neighborhood Hits	161	Target Neighborhood Hits	916	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CP135_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.043364 (rank : 100)
Query Neighborhood Hits	161	Target Neighborhood Hits	1278	Shared Neighborhood Hits	108
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

ITSN2_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.038012 (rank : 118)
Query Neighborhood Hits	161	Target Neighborhood Hits	1371	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

LIPA2_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.052129 (rank : 72)
Query Neighborhood Hits	161	Target Neighborhood Hits	1282	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

NAL13_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.002554 (rank : 186)
Query Neighborhood Hits	161	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

OFD1_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.062032 (rank : 37)
Query Neighborhood Hits	161	Target Neighborhood Hits	753	Shared Neighborhood Hits	87
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

PP16A_MOUSE
θ value	6.88961 (rank : 130)	NC score	-0.000514 (rank : 188)
Query Neighborhood Hits	161	Target Neighborhood Hits	318	Shared Neighborhood Hits	2
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

RAB15_MOUSE
θ value	6.88961 (rank : 131)	NC score	0.010680 (rank : 173)
Query Neighborhood Hits	161	Target Neighborhood Hits	284	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K386	Gene names	Rab15
Domain Architecture
Description	Ras-related protein Rab-15.

RAD50_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.038739 (rank : 115)
Query Neighborhood Hits	161	Target Neighborhood Hits	1317	Shared Neighborhood Hits	106
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

REST_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.047428 (rank : 84)
Query Neighborhood Hits	161	Target Neighborhood Hits	1605	Shared Neighborhood Hits	107
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

RPGR1_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.023536 (rank : 147)
Query Neighborhood Hits	161	Target Neighborhood Hits	713	Shared Neighborhood Hits	67
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

TWST2_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.007281 (rank : 180)
Query Neighborhood Hits	161	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.007296 (rank : 179)
Query Neighborhood Hits	161	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

U2AFL_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.039071 (rank : 112)
Query Neighborhood Hits	161	Target Neighborhood Hits	389	Shared Neighborhood Hits	58
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

UBXD8_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.016076 (rank : 159)
Query Neighborhood Hits	161	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	Q3TDN2, Q3U9W2, Q80TP7, Q80W42	Gene names	Ubxd8, Kiaa0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8.

CCD46_MOUSE
θ value	8.99809 (rank : 139)	NC score	0.058170 (rank : 46)
Query Neighborhood Hits	161	Target Neighborhood Hits	1405	Shared Neighborhood Hits	115
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CD2L1_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.002507 (rank : 187)
Query Neighborhood Hits	161	Target Neighborhood Hits	1467	Shared Neighborhood Hits	59
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

EEA1_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.036489 (rank : 124)
Query Neighborhood Hits	161	Target Neighborhood Hits	1796	Shared Neighborhood Hits	107
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EEA1_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.037834 (rank : 120)
Query Neighborhood Hits	161	Target Neighborhood Hits	1637	Shared Neighborhood Hits	108
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GCP60_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.033164 (rank : 133)
Query Neighborhood Hits	161	Target Neighborhood Hits	395	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GDIT_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.004579 (rank : 182)
Query Neighborhood Hits	161	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q99819, Q4TT69, Q96S29	Gene names	ARHGDIG
Domain Architecture
Description	Rho GDP-dissociation inhibitor 3 (Rho GDI 3) (Rho-GDI gamma).

GOGA2_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.037642 (rank : 122)
Query Neighborhood Hits	161	Target Neighborhood Hits	944	Shared Neighborhood Hits	95
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GOGA4_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.064289 (rank : 32)
Query Neighborhood Hits	161	Target Neighborhood Hits	1939	Shared Neighborhood Hits	122
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

INCE_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.042322 (rank : 103)
Query Neighborhood Hits	161	Target Neighborhood Hits	903	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

KIF5C_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.032838 (rank : 134)
Query Neighborhood Hits	161	Target Neighborhood Hits	1040	Shared Neighborhood Hits	103
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

MOES_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.020462 (rank : 153)
Query Neighborhood Hits	161	Target Neighborhood Hits	892	Shared Neighborhood Hits	91
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MYO6_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.018593 (rank : 155)
Query Neighborhood Hits	161	Target Neighborhood Hits	727	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

PTN2_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.006322 (rank : 181)
Query Neighborhood Hits	161	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

RAB13_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.008146 (rank : 176)
Query Neighborhood Hits	161	Target Neighborhood Hits	286	Shared Neighborhood Hits	17
SwissProt Accessions	P51153, Q96GU4	Gene names	RAB13
Domain Architecture
Description	Ras-related protein Rab-13.

RAB1A_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.012891 (rank : 166)
Query Neighborhood Hits	161	Target Neighborhood Hits	292	Shared Neighborhood Hits	20
SwissProt Accessions	P62820, P11476, Q96N61, Q9Y3T2	Gene names	RAB1A, RAB1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-1A (YPT1-related protein).

RAB1A_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.012891 (rank : 167)
Query Neighborhood Hits	161	Target Neighborhood Hits	292	Shared Neighborhood Hits	20
SwissProt Accessions	P62821, P11476, Q3TX44, Q811M4, Q96N61, Q9Y3T2	Gene names	Rab1A, Rab1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-1A (YPT1-related protein).

RAB1B_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.014530 (rank : 162)
Query Neighborhood Hits	161	Target Neighborhood Hits	295	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H0U4	Gene names	RAB1B
Domain Architecture
Description	Ras-related protein Rab-1B.

RAB1B_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.014547 (rank : 161)
Query Neighborhood Hits	161	Target Neighborhood Hits	296	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D1G1, Q3U0N1	Gene names	Rab1b
Domain Architecture
Description	Ras-related protein Rab-1B.

RAD50_MOUSE
θ value	8.99809 (rank : 157)	NC score	0.048278 (rank : 83)
Query Neighborhood Hits	161	Target Neighborhood Hits	1366	Shared Neighborhood Hits	111
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

REN3A_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.024840 (rank : 145)
Query Neighborhood Hits	161	Target Neighborhood Hits	248	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

SUV91_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.004491 (rank : 183)
Query Neighborhood Hits	161	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

TAF3_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.015121 (rank : 160)
Query Neighborhood Hits	161	Target Neighborhood Hits	463	Shared Neighborhood Hits	36
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

UBP37_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.003453 (rank : 184)
Query Neighborhood Hits	161	Target Neighborhood Hits	208	Shared Neighborhood Hits	15
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

APOA1_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.059361 (rank : 42)
Query Neighborhood Hits	161	Target Neighborhood Hits	262	Shared Neighborhood Hits	42
SwissProt Accessions	P02647, Q6LDN9, Q6Q785	Gene names	APOA1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) [Contains: Apolipoprotein A-I(1-242)].

CCD41_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.059127 (rank : 43)
Query Neighborhood Hits	161	Target Neighborhood Hits	1139	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD46_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.056870 (rank : 51)
Query Neighborhood Hits	161	Target Neighborhood Hits	1430	Shared Neighborhood Hits	117
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD96_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.055057 (rank : 58)
Query Neighborhood Hits	161	Target Neighborhood Hits	704	Shared Neighborhood Hits	94
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CE290_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.057890 (rank : 48)
Query Neighborhood Hits	161	Target Neighborhood Hits	1553	Shared Neighborhood Hits	109
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CEP63_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.051041 (rank : 74)
Query Neighborhood Hits	161	Target Neighborhood Hits	1005	Shared Neighborhood Hits	102
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CI039_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.052934 (rank : 66)
Query Neighborhood Hits	161	Target Neighborhood Hits	1171	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CK5P2_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.062624 (rank : 36)
Query Neighborhood Hits	161	Target Neighborhood Hits	1433	Shared Neighborhood Hits	112
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CP135_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.052387 (rank : 70)
Query Neighborhood Hits	161	Target Neighborhood Hits	1290	Shared Neighborhood Hits	105
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GCC2_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.053147 (rank : 64)
Query Neighborhood Hits	161	Target Neighborhood Hits	1619	Shared Neighborhood Hits	111
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGA5_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.050012 (rank : 76)
Query Neighborhood Hits	161	Target Neighborhood Hits	1434	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

HIP1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.052010 (rank : 73)
Query Neighborhood Hits	161	Target Neighborhood Hits	1016	Shared Neighborhood Hits	106
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

MAP1A_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.055384 (rank : 57)
Query Neighborhood Hits	161	Target Neighborhood Hits	1626	Shared Neighborhood Hits	108
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NAF1_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.055731 (rank : 55)
Query Neighborhood Hits	161	Target Neighborhood Hits	937	Shared Neighborhood Hits	97
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NAF1_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.053131 (rank : 65)
Query Neighborhood Hits	161	Target Neighborhood Hits	852	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NUF2_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.054726 (rank : 59)
Query Neighborhood Hits	161	Target Neighborhood Hits	661	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

PHLB2_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.057262 (rank : 49)
Query Neighborhood Hits	161	Target Neighborhood Hits	964	Shared Neighborhood Hits	96
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.056997 (rank : 50)
Query Neighborhood Hits	161	Target Neighborhood Hits	1016	Shared Neighborhood Hits	99
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

RUFY2_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.056589 (rank : 52)
Query Neighborhood Hits	161	Target Neighborhood Hits	1208	Shared Neighborhood Hits	106
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SMC1A_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.054368 (rank : 60)
Query Neighborhood Hits	161	Target Neighborhood Hits	1346	Shared Neighborhood Hits	115
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.053736 (rank : 62)
Query Neighborhood Hits	161	Target Neighborhood Hits	1384	Shared Neighborhood Hits	115
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC2_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.069013 (rank : 29)
Query Neighborhood Hits	161	Target Neighborhood Hits	1405	Shared Neighborhood Hits	111
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC2_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.061658 (rank : 38)
Query Neighborhood Hits	161	Target Neighborhood Hits	1131	Shared Neighborhood Hits	107
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SPC25_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.076611 (rank : 27)
Query Neighborhood Hits	161	Target Neighborhood Hits	273	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HBM1	Gene names	SPBC25, SPC25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25 (hSpc25).

STMN1_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.052814 (rank : 68)
Query Neighborhood Hits	161	Target Neighborhood Hits	554	Shared Neighborhood Hits	81
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

STMN1_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.052356 (rank : 71)
Query Neighborhood Hits	161	Target Neighborhood Hits	560	Shared Neighborhood Hits	79
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

ZWINT_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.071605 (rank : 28)
Query Neighborhood Hits	161	Target Neighborhood Hits	497	Shared Neighborhood Hits	75
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

Hits sorted by NC score

SEP10_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	161
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.

SEP10_MOUSE
NC score	0.994087 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	161	Target Neighborhood Hits	145	Shared Neighborhood Hits	94
SwissProt Accessions	Q8C650, Q7TSA5	Gene names	Sept10
Domain Architecture	No domain graphic available
Description	Septin-10.

SEPT6_HUMAN
NC score	0.980370 (rank : 3)	θ value	2.17943e-171 (rank : 5)
Query Neighborhood Hits	161	Target Neighborhood Hits	220	Shared Neighborhood Hits	60
SwissProt Accessions	Q14141, Q5JTK0, Q969W5, Q96A13, Q96GR1, Q96P86, Q96P87	Gene names	SEPT6, KIAA0128, SEP2
Domain Architecture
Description	Septin-6.

SEPT6_MOUSE
NC score	0.978646 (rank : 4)	θ value	4.11024e-170 (rank : 6)
Query Neighborhood Hits	161	Target Neighborhood Hits	244	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R1T4, Q91XH2, Q9CZ94	Gene names	Sept6
Domain Architecture
Description	Septin-6.

SEPT8_MOUSE
NC score	0.973393 (rank : 5)	θ value	4.25343e-167 (rank : 8)
Query Neighborhood Hits	161	Target Neighborhood Hits	251	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CHH9, Q80YC7, Q9ESF7	Gene names	Sept8, Kiaa0202
Domain Architecture
Description	Septin-8.

SEP11_HUMAN
NC score	0.969359 (rank : 6)	θ value	8.84838e-173 (rank : 4)
Query Neighborhood Hits	161	Target Neighborhood Hits	296	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NVA2, Q7L4N1	Gene names	SEPT11
Domain Architecture	No domain graphic available
Description	Septin-11.

SEP11_MOUSE
NC score	0.968512 (rank : 7)	θ value	4.6918e-174 (rank : 3)
Query Neighborhood Hits	161	Target Neighborhood Hits	300	Shared Neighborhood Hits	73
SwissProt Accessions	Q8C1B7, Q6P2K5, Q6P6I0	Gene names	Sept11, D5Ertd606e
Domain Architecture	No domain graphic available
Description	Septin-11.

SEPT8_HUMAN
NC score	0.968060 (rank : 8)	θ value	5.93515e-169 (rank : 7)
Query Neighborhood Hits	161	Target Neighborhood Hits	290	Shared Neighborhood Hits	70
SwissProt Accessions	Q92599, Q8IX36, Q8IX37, Q9BVB3	Gene names	SEPT8, KIAA0202
Domain Architecture
Description	Septin-8.

SEPT3_HUMAN
NC score	0.957619 (rank : 9)	θ value	1.71981e-67 (rank : 11)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UH03, Q6IBZ6, Q8N3P3	Gene names	SEPT3, SEP3
Domain Architecture
Description	Neuronal-specific septin-3.

SEPT3_MOUSE
NC score	0.953259 (rank : 10)	θ value	5.7252e-63 (rank : 21)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1S5	Gene names	Sept3, Sep3
Domain Architecture
Description	Neuronal-specific septin-3.

SEPT2_HUMAN
NC score	0.950935 (rank : 11)	θ value	3.96481e-64 (rank : 20)
Query Neighborhood Hits	161	Target Neighborhood Hits	101	Shared Neighborhood Hits	35
SwissProt Accessions	Q15019, Q14132, Q8IUK9, Q96CB0	Gene names	SEPT2, DIFF6, KIAA0158, NEDD5
Domain Architecture
Description	Septin-2 (Protein NEDD5).

SEPT2_MOUSE
NC score	0.950456 (rank : 12)	θ value	3.03575e-64 (rank : 19)
Query Neighborhood Hits	161	Target Neighborhood Hits	105	Shared Neighborhood Hits	34
SwissProt Accessions	P42208, Q3U9Y5	Gene names	Sept2, Nedd-5, Nedd5
Domain Architecture
Description	Septin-2 (Protein NEDD5) (Neural precursor cell expressed developmentally down-regulated protein 5).

SEPT5_MOUSE
NC score	0.950280 (rank : 13)	θ value	5.00389e-67 (rank : 14)
Query Neighborhood Hits	161	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z2Q6, Q3UYG4, Q6PB74	Gene names	Sept5, Pnutl1
Domain Architecture	No domain graphic available
Description	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1).

SEPT5_HUMAN
NC score	0.949677 (rank : 14)	θ value	3.83135e-67 (rank : 13)
Query Neighborhood Hits	161	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q99719, O15251	Gene names	SEPT5, PNUTL1
Domain Architecture
Description	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1).

SEPT1_HUMAN
NC score	0.949332 (rank : 15)	θ value	3.03575e-64 (rank : 18)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WYJ6, Q8NEZ1, Q96EL4, Q9H285	Gene names	SEPT1, PNUTL3
Domain Architecture
Description	Septin-1 (LARP) (Serologically defined breast cancer antigen NY-BR- 24).

SEPT1_MOUSE
NC score	0.948750 (rank : 16)	θ value	1.19377e-60 (rank : 22)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	P42209	Gene names	Sept1, Diff6, Pnutl3
Domain Architecture
Description	Septin-1 (Differentiation protein 6) (Diff6 protein).

SEPT4_MOUSE
NC score	0.946237 (rank : 17)	θ value	2.24614e-67 (rank : 12)
Query Neighborhood Hits	161	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	P28661, Q5ND15	Gene names	Sept4, Pnutl2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5).

SEPT4_HUMAN
NC score	0.945508 (rank : 18)	θ value	8.53533e-67 (rank : 15)
Query Neighborhood Hits	161	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	O43236, Q9UM58	Gene names	SEPT4, PNUTL2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5) (Cell division control-related protein 2) (hCDCREL-2) (Bradeion beta) (CE5B3 beta) (Cerebral protein 7).

SEPT7_HUMAN
NC score	0.934331 (rank : 19)	θ value	6.73165e-80 (rank : 9)
Query Neighborhood Hits	161	Target Neighborhood Hits	385	Shared Neighborhood Hits	100
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SEPT7_MOUSE
NC score	0.933239 (rank : 20)	θ value	6.73165e-80 (rank : 10)
Query Neighborhood Hits	161	Target Neighborhood Hits	327	Shared Neighborhood Hits	78
SwissProt Accessions	O55131	Gene names	Sept7, Cdc10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SEPT9_MOUSE
NC score	0.923650 (rank : 21)	θ value	6.11685e-65 (rank : 17)
Query Neighborhood Hits	161	Target Neighborhood Hits	238	Shared Neighborhood Hits	29
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SEPT9_HUMAN
NC score	0.866314 (rank : 22)	θ value	2.74572e-65 (rank : 16)
Query Neighborhood Hits	161	Target Neighborhood Hits	706	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SWP70_MOUSE
NC score	0.084451 (rank : 23)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	161	Target Neighborhood Hits	1097	Shared Neighborhood Hits	110
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

WBP11_MOUSE
NC score	0.082068 (rank : 24)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	161	Target Neighborhood Hits	362	Shared Neighborhood Hits	25
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBP11_HUMAN
NC score	0.080779 (rank : 25)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	161	Target Neighborhood Hits	354	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

RBCC1_MOUSE
NC score	0.080636 (rank : 26)	θ value	0.163984 (rank : 29)
Query Neighborhood Hits	161	Target Neighborhood Hits	1048	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

SPC25_HUMAN
NC score	0.076611 (rank : 27)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	161	Target Neighborhood Hits	273	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HBM1	Gene names	SPBC25, SPC25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25 (hSpc25).

ZWINT_MOUSE
NC score	0.071605 (rank : 28)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	161	Target Neighborhood Hits	497	Shared Neighborhood Hits	75
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

SMC2_HUMAN
NC score	0.069013 (rank : 29)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	161	Target Neighborhood Hits	1405	Shared Neighborhood Hits	111
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SKIL_MOUSE
NC score	0.067677 (rank : 30)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	161	Target Neighborhood Hits	719	Shared Neighborhood Hits	87
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

GRAP1_MOUSE
NC score	0.064627 (rank : 31)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	161	Target Neighborhood Hits	1234	Shared Neighborhood Hits	114
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GOGA4_MOUSE
NC score	0.064289 (rank : 32)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	161	Target Neighborhood Hits	1939	Shared Neighborhood Hits	122
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CCD91_HUMAN
NC score	0.063359 (rank : 33)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	161	Target Neighborhood Hits	868	Shared Neighborhood Hits	104
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CENPF_HUMAN
NC score	0.063153 (rank : 34)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	161	Target Neighborhood Hits	1932	Shared Neighborhood Hits	112
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

LIPA1_HUMAN
NC score	0.063057 (rank : 35)	θ value	0.125558 (rank : 28)
Query Neighborhood Hits	161	Target Neighborhood Hits	1294	Shared Neighborhood Hits	118
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

CK5P2_HUMAN
NC score	0.062624 (rank : 36)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	161	Target Neighborhood Hits	1433	Shared Neighborhood Hits	112
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

OFD1_HUMAN
NC score	0.062032 (rank : 37)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	161	Target Neighborhood Hits	753	Shared Neighborhood Hits	87
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

SMC2_MOUSE
NC score	0.061658 (rank : 38)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	161	Target Neighborhood Hits	1131	Shared Neighborhood Hits	107
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SYCP1_MOUSE
NC score	0.061420 (rank : 39)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	161	Target Neighborhood Hits	1456	Shared Neighborhood Hits	111
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

GOGA4_HUMAN
NC score	0.061225 (rank : 40)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	161	Target Neighborhood Hits	2034	Shared Neighborhood Hits	118
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

SWP70_HUMAN
NC score	0.060146 (rank : 41)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	161	Target Neighborhood Hits	973	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

APOA1_HUMAN
NC score	0.059361 (rank : 42)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	161	Target Neighborhood Hits	262	Shared Neighborhood Hits	42
SwissProt Accessions	P02647, Q6LDN9, Q6Q785	Gene names	APOA1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) [Contains: Apolipoprotein A-I(1-242)].

CCD41_HUMAN
NC score	0.059127 (rank : 43)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	161	Target Neighborhood Hits	1139	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

GOGB1_HUMAN
NC score	0.058728 (rank : 44)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	161	Target Neighborhood Hits	2297	Shared Neighborhood Hits	118
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

BICD1_MOUSE
NC score	0.058319 (rank : 45)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	161	Target Neighborhood Hits	837	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CCD46_MOUSE
NC score	0.058170 (rank : 46)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	161	Target Neighborhood Hits	1405	Shared Neighborhood Hits	115
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

BICD2_MOUSE
NC score	0.057898 (rank : 47)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	161	Target Neighborhood Hits	864	Shared Neighborhood Hits	94
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CE290_HUMAN
NC score	0.057890 (rank : 48)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	161	Target Neighborhood Hits	1553	Shared Neighborhood Hits	109
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

PHLB2_HUMAN
NC score	0.057262 (rank : 49)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	161	Target Neighborhood Hits	964	Shared Neighborhood Hits	96
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_MOUSE
NC score	0.056997 (rank : 50)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	161	Target Neighborhood Hits	1016	Shared Neighborhood Hits	99
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

CCD46_HUMAN
NC score	0.056870 (rank : 51)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	161	Target Neighborhood Hits	1430	Shared Neighborhood Hits	117
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

RUFY2_HUMAN
NC score	0.056589 (rank : 52)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	161	Target Neighborhood Hits	1208	Shared Neighborhood Hits	106
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RRBP1_MOUSE
NC score	0.056569 (rank : 53)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	161	Target Neighborhood Hits	1650	Shared Neighborhood Hits	111
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

TCRG1_MOUSE
NC score	0.056169 (rank : 54)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	161	Target Neighborhood Hits	947	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

NAF1_HUMAN
NC score	0.055731 (rank : 55)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	161	Target Neighborhood Hits	937	Shared Neighborhood Hits	97
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

DESP_HUMAN
NC score	0.055654 (rank : 56)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	161	Target Neighborhood Hits	1470	Shared Neighborhood Hits	117
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

MAP1A_HUMAN
NC score	0.055384 (rank : 57)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	161	Target Neighborhood Hits	1626	Shared Neighborhood Hits	108
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

CCD96_MOUSE
NC score	0.055057 (rank : 58)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	161	Target Neighborhood Hits	704	Shared Neighborhood Hits	94
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

NUF2_HUMAN
NC score	0.054726 (rank : 59)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	161	Target Neighborhood Hits	661	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

SMC1A_HUMAN
NC score	0.054368 (rank : 60)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	161	Target Neighborhood Hits	1346	Shared Neighborhood Hits	115
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

TCRG1_HUMAN
NC score	0.054092 (rank : 61)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	161	Target Neighborhood Hits	929	Shared Neighborhood Hits	93
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

SMC1A_MOUSE
NC score	0.053736 (rank : 62)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	161	Target Neighborhood Hits	1384	Shared Neighborhood Hits	115
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

BICD2_HUMAN
NC score	0.053706 (rank : 63)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	161	Target Neighborhood Hits	856	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

GCC2_MOUSE
NC score	0.053147 (rank : 64)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	161	Target Neighborhood Hits	1619	Shared Neighborhood Hits	111
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

NAF1_MOUSE
NC score	0.053131 (rank : 65)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	161	Target Neighborhood Hits	852	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

CI039_HUMAN
NC score	0.052934 (rank : 66)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	161	Target Neighborhood Hits	1171	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

U2AFM_HUMAN
NC score	0.052864 (rank : 67)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	161	Target Neighborhood Hits	577	Shared Neighborhood Hits	76
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

STMN1_HUMAN
NC score	0.052814 (rank : 68)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	161	Target Neighborhood Hits	554	Shared Neighborhood Hits	81
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

CING_HUMAN
NC score	0.052532 (rank : 69)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	161	Target Neighborhood Hits	1275	Shared Neighborhood Hits	109
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CP135_HUMAN
NC score	0.052387 (rank : 70)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	161	Target Neighborhood Hits	1290	Shared Neighborhood Hits	105
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

STMN1_MOUSE
NC score	0.052356 (rank : 71)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	161	Target Neighborhood Hits	560	Shared Neighborhood Hits	79
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

LIPA2_MOUSE
NC score	0.052129 (rank : 72)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	161	Target Neighborhood Hits	1282	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

HIP1_HUMAN
NC score	0.052010 (rank : 73)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	161	Target Neighborhood Hits	1016	Shared Neighborhood Hits	106
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

CEP63_HUMAN
NC score	0.051041 (rank : 74)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	161	Target Neighborhood Hits	1005	Shared Neighborhood Hits	102
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

GRAP1_HUMAN
NC score	0.050967 (rank : 75)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	161	Target Neighborhood Hits	944	Shared Neighborhood Hits	97
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

GOGA5_MOUSE
NC score	0.050012 (rank : 76)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	161	Target Neighborhood Hits	1434	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

PCNT_MOUSE
NC score	0.049590 (rank : 77)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	161	Target Neighborhood Hits	1207	Shared Neighborhood Hits	105
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

BICD1_HUMAN
NC score	0.049035 (rank : 78)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	161	Target Neighborhood Hits	844	Shared Neighborhood Hits	94
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

LIPA2_HUMAN
NC score	0.048756 (rank : 79)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	161	Target Neighborhood Hits	1044	Shared Neighborhood Hits	96
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

INCE_HUMAN
NC score	0.048611 (rank : 80)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	161	Target Neighborhood Hits	978	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

CP250_MOUSE
NC score	0.048563 (rank : 81)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	161	Target Neighborhood Hits	1583	Shared Neighborhood Hits	113
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

BEGIN_HUMAN
NC score	0.048546 (rank : 82)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	161	Target Neighborhood Hits	454	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

RAD50_MOUSE
NC score	0.048278 (rank : 83)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	161	Target Neighborhood Hits	1366	Shared Neighborhood Hits	111
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

REST_HUMAN
NC score	0.047428 (rank : 84)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	161	Target Neighborhood Hits	1605	Shared Neighborhood Hits	107
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

AKAP9_HUMAN
NC score	0.047266 (rank : 85)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	161	Target Neighborhood Hits	1710	Shared Neighborhood Hits	116
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

RABE1_MOUSE
NC score	0.046940 (rank : 86)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	161	Target Neighborhood Hits	1105	Shared Neighborhood Hits	104
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

GOGA6_HUMAN
NC score	0.046587 (rank : 87)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	161	Target Neighborhood Hits	1007	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

RB6I2_HUMAN
NC score	0.046497 (rank : 88)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	161	Target Neighborhood Hits	1584	Shared Neighborhood Hits	115
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

ZN291_HUMAN
NC score	0.045842 (rank : 89)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	161	Target Neighborhood Hits	647	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

CCD39_HUMAN
NC score	0.045702 (rank : 90)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	161	Target Neighborhood Hits	868	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

MYH9_MOUSE
NC score	0.045556 (rank : 91)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	161	Target Neighborhood Hits	1829	Shared Neighborhood Hits	117
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

HIP1R_MOUSE
NC score	0.045420 (rank : 92)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	161	Target Neighborhood Hits	959	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

U2AFM_MOUSE
NC score	0.045025 (rank : 93)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	161	Target Neighborhood Hits	543	Shared Neighborhood Hits	68
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

U2AFL_HUMAN
NC score	0.044681 (rank : 94)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	161	Target Neighborhood Hits	503	Shared Neighborhood Hits	69
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

RBP24_HUMAN
NC score	0.044633 (rank : 95)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	161	Target Neighborhood Hits	1559	Shared Neighborhood Hits	109
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.044615 (rank : 96)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	161	Target Neighborhood Hits	1558	Shared Neighborhood Hits	110
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RB6I2_MOUSE
NC score	0.044493 (rank : 97)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	161	Target Neighborhood Hits	1433	Shared Neighborhood Hits	111
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

CTGE5_HUMAN
NC score	0.044462 (rank : 98)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	161	Target Neighborhood Hits	800	Shared Neighborhood Hits	86
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

MYH9_HUMAN
NC score	0.044079 (rank : 99)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	161	Target Neighborhood Hits	1762	Shared Neighborhood Hits	117
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CP135_MOUSE
NC score	0.043364 (rank : 100)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	161	Target Neighborhood Hits	1278	Shared Neighborhood Hits	108
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

TACC3_MOUSE
NC score	0.042890 (rank : 101)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	161	Target Neighborhood Hits	607	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

PEPL_MOUSE
NC score	0.042807 (rank : 102)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	161	Target Neighborhood Hits	1105	Shared Neighborhood Hits	104
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

INCE_MOUSE
NC score	0.042322 (rank : 103)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	161	Target Neighborhood Hits	903	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

ITSN1_MOUSE
NC score	0.041839 (rank : 104)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	161	Target Neighborhood Hits	1669	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

BPAEA_MOUSE
NC score	0.041530 (rank : 105)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	161	Target Neighborhood Hits	1480	Shared Neighborhood Hits	107
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BEGIN_MOUSE
NC score	0.041438 (rank : 106)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	161	Target Neighborhood Hits	383	Shared Neighborhood Hits	59
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

DMD_HUMAN
NC score	0.041368 (rank : 107)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	161	Target Neighborhood Hits	1135	Shared Neighborhood Hits	107
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

IF3A_MOUSE
NC score	0.040464 (rank : 108)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	161	Target Neighborhood Hits	871	Shared Neighborhood Hits	97
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IF3A_HUMAN
NC score	0.040175 (rank : 109)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	161	Target Neighborhood Hits	875	Shared Neighborhood Hits	98
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

TRHY_HUMAN
NC score	0.039934 (rank : 110)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	161	Target Neighborhood Hits	1385	Shared Neighborhood Hits	95
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

NIN_MOUSE
NC score	0.039446 (rank : 111)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	161	Target Neighborhood Hits	1376	Shared Neighborhood Hits	110
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

U2AFL_MOUSE
NC score	0.039071 (rank : 112)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	161	Target Neighborhood Hits	389	Shared Neighborhood Hits	58
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

CN145_MOUSE
NC score	0.038972 (rank : 113)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	161	Target Neighborhood Hits	916	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CAF1A_MOUSE
NC score	0.038781 (rank : 114)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	161	Target Neighborhood Hits	736	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

RAD50_HUMAN
NC score	0.038739 (rank : 115)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	161	Target Neighborhood Hits	1317	Shared Neighborhood Hits	106
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

KMHN1_HUMAN
NC score	0.038468 (rank : 116)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	161	Target Neighborhood Hits	950	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

NUCB2_MOUSE
NC score	0.038394 (rank : 117)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	161	Target Neighborhood Hits	459	Shared Neighborhood Hits	72
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

ITSN2_MOUSE
NC score	0.038012 (rank : 118)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	161	Target Neighborhood Hits	1371	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

LIPA3_HUMAN
NC score	0.037912 (rank : 119)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	161	Target Neighborhood Hits	828	Shared Neighborhood Hits	85
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

EEA1_MOUSE
NC score	0.037834 (rank : 120)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	161	Target Neighborhood Hits	1637	Shared Neighborhood Hits	108
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

LIPA3_MOUSE
NC score	0.037673 (rank : 121)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	161	Target Neighborhood Hits	636	Shared Neighborhood Hits	75
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

GOGA2_MOUSE
NC score	0.037642 (rank : 122)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	161	Target Neighborhood Hits	944	Shared Neighborhood Hits	95
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

LMNB1_MOUSE
NC score	0.036592 (rank : 123)	θ value	0.279714 (rank : 31)
Query Neighborhood Hits	161	Target Neighborhood Hits	719	Shared Neighborhood Hits	84
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

EEA1_HUMAN
NC score	0.036489 (rank : 124)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	161	Target Neighborhood Hits	1796	Shared Neighborhood Hits	107
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

CTRO_MOUSE
NC score	0.036302 (rank : 125)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	161	Target Neighborhood Hits	2344	Shared Neighborhood Hits	114
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

VP13A_HUMAN
NC score	0.036158 (rank : 126)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	161	Target Neighborhood Hits	93	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

PININ_MOUSE
NC score	0.035446 (rank : 127)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	161	Target Neighborhood Hits	777	Shared Neighborhood Hits	85
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

LMNB1_HUMAN
NC score	0.034502 (rank : 128)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	161	Target Neighborhood Hits	714	Shared Neighborhood Hits	83
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

LRSM1_HUMAN
NC score	0.034410 (rank : 129)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	161	Target Neighborhood Hits	1078	Shared Neighborhood Hits	97
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

IF2P_HUMAN
NC score	0.034369 (rank : 130)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	161	Target Neighborhood Hits	889	Shared Neighborhood Hits	74
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

PLEC1_HUMAN
NC score	0.033913 (rank : 131)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	161	Target Neighborhood Hits	1326	Shared Neighborhood Hits	94
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SM1L2_MOUSE
NC score	0.033629 (rank : 132)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	161	Target Neighborhood Hits	918	Shared Neighborhood Hits	93
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

GCP60_MOUSE
NC score	0.033164 (rank : 133)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	161	Target Neighborhood Hits	395	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

KIF5C_MOUSE
NC score	0.032838 (rank : 134)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	161	Target Neighborhood Hits	1040	Shared Neighborhood Hits	103
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

BRE1A_MOUSE
NC score	0.031878 (rank : 135)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	161	Target Neighborhood Hits	1025	Shared Neighborhood Hits	82
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

GCP60_HUMAN
NC score	0.031685 (rank : 136)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	161	Target Neighborhood Hits	419	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

CAPS2_HUMAN
NC score	0.029783 (rank : 137)	θ value	0.279714 (rank : 30)
Query Neighborhood Hits	161	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8	Gene names	CADPS2, CAPS2, KIAA1591
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

GBP2_MOUSE
NC score	0.029043 (rank : 138)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	161	Target Neighborhood Hits	323	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z0E6, Q8CIC6, Q921N2, Q9R1I0	Gene names	Gbp2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (mGBP2) (mGBP-2).

CAPS2_MOUSE
NC score	0.028922 (rank : 139)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	161	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BYR5, O08903, Q66JM7, Q6PCL7, Q76I88, Q7TMM6, Q80ZV8, Q8BL25, Q8BY04, Q8K3K6	Gene names	Cadps2, Caps2
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

PKHG1_HUMAN
NC score	0.028218 (rank : 140)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	161	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

MYO5A_MOUSE
NC score	0.027838 (rank : 141)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	161	Target Neighborhood Hits	1117	Shared Neighborhood Hits	104
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

TF2H1_MOUSE
NC score	0.025839 (rank : 142)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	161	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBA9, O35637	Gene names	Gtf2h1
Domain Architecture
Description	TFIIH basal transcription factor complex p62 subunit (Basic transcription factor 62 kDa subunit) (BTF2-p62) (General transcription factor IIH polypeptide 1).

TF2H1_HUMAN
NC score	0.025835 (rank : 143)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	161	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P32780, Q9H5K5, Q9NQD9	Gene names	GTF2H1, BTF2
Domain Architecture
Description	TFIIH basal transcription factor complex p62 subunit (Basic transcription factor 62 kDa subunit) (BTF2-p62) (General transcription factor IIH polypeptide 1).

GBP1_HUMAN
NC score	0.024880 (rank : 144)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	161	Target Neighborhood Hits	339	Shared Neighborhood Hits	61
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

REN3A_HUMAN
NC score	0.024840 (rank : 145)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	161	Target Neighborhood Hits	248	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

RNF8_MOUSE
NC score	0.024161 (rank : 146)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	161	Target Neighborhood Hits	618	Shared Neighborhood Hits	71
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RPGR1_MOUSE
NC score	0.023536 (rank : 147)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	161	Target Neighborhood Hits	713	Shared Neighborhood Hits	67
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

MRCKB_HUMAN
NC score	0.023399 (rank : 148)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	161	Target Neighborhood Hits	2239	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYO5B_HUMAN
NC score	0.022677 (rank : 149)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	161	Target Neighborhood Hits	911	Shared Neighborhood Hits	97
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MAT1_MOUSE
NC score	0.021775 (rank : 150)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	161	Target Neighborhood Hits	217	Shared Neighborhood Hits	33
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MICA1_MOUSE
NC score	0.021759 (rank : 151)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	161	Target Neighborhood Hits	400	Shared Neighborhood Hits	58
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MAT1_HUMAN
NC score	0.020631 (rank : 152)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	161	Target Neighborhood Hits	179	Shared Neighborhood Hits	30
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MOES_HUMAN
NC score	0.020462 (rank : 153)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	161	Target Neighborhood Hits	892	Shared Neighborhood Hits	91
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

RN168_HUMAN
NC score	0.019897 (rank : 154)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	161	Target Neighborhood Hits	370	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

MYO6_HUMAN
NC score	0.018593 (rank : 155)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	161	Target Neighborhood Hits	727	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

FYB_MOUSE
NC score	0.018106 (rank : 156)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	161	Target Neighborhood Hits	194	Shared Neighborhood Hits	8
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

OXR1_MOUSE
NC score	0.017850 (rank : 157)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	161	Target Neighborhood Hits	516	Shared Neighborhood Hits	36
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

UBXD8_HUMAN
NC score	0.016622 (rank : 158)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	161	Target Neighborhood Hits	131	Shared Neighborhood Hits	20
SwissProt Accessions	Q96CS3, O94963, Q8IUF2, Q9BRP2, Q9BVM7	Gene names	UBXD8, ETEA, KIAA0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8 (Protein ETEA).

UBXD8_MOUSE
NC score	0.016076 (rank : 159)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	161	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	Q3TDN2, Q3U9W2, Q80TP7, Q80W42	Gene names	Ubxd8, Kiaa0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8.

TAF3_MOUSE
NC score	0.015121 (rank : 160)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	161	Target Neighborhood Hits	463	Shared Neighborhood Hits	36
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

RAB1B_MOUSE
NC score	0.014547 (rank : 161)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	161	Target Neighborhood Hits	296	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D1G1, Q3U0N1	Gene names	Rab1b
Domain Architecture
Description	Ras-related protein Rab-1B.

RAB1B_HUMAN
NC score	0.014530 (rank : 162)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	161	Target Neighborhood Hits	295	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H0U4	Gene names	RAB1B
Domain Architecture
Description	Ras-related protein Rab-1B.

RAB15_HUMAN
NC score	0.013916 (rank : 163)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	161	Target Neighborhood Hits	283	Shared Neighborhood Hits	18
SwissProt Accessions	P59190, Q86TX7, Q8IW89	Gene names	RAB15
Domain Architecture
Description	Ras-related protein Rab-15.

CECR2_HUMAN
NC score	0.013461 (rank : 164)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	161	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

FYB_HUMAN
NC score	0.013372 (rank : 165)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	161	Target Neighborhood Hits	379	Shared Neighborhood Hits	12
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

RAB1A_HUMAN
NC score	0.012891 (rank : 166)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	161	Target Neighborhood Hits	292	Shared Neighborhood Hits	20
SwissProt Accessions	P62820, P11476, Q96N61, Q9Y3T2	Gene names	RAB1A, RAB1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-1A (YPT1-related protein).

RAB1A_MOUSE
NC score	0.012891 (rank : 167)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	161	Target Neighborhood Hits	292	Shared Neighborhood Hits	20
SwissProt Accessions	P62821, P11476, Q3TX44, Q811M4, Q96N61, Q9Y3T2	Gene names	Rab1A, Rab1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-1A (YPT1-related protein).

DBP_MOUSE
NC score	0.011745 (rank : 168)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	161	Target Neighborhood Hits	137	Shared Neighborhood Hits	11
SwissProt Accessions	Q60925, Q8VCX3	Gene names	Dbp
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein).

MEFV_HUMAN
NC score	0.011122 (rank : 169)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	161	Target Neighborhood Hits	431	Shared Neighborhood Hits	45
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

DBP_HUMAN
NC score	0.010936 (rank : 170)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	161	Target Neighborhood Hits	136	Shared Neighborhood Hits	11
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

RAB10_HUMAN
NC score	0.010765 (rank : 171)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	161	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	P61026, O88386, Q6IA52, Q9D7X6, Q9H0T3	Gene names	RAB10
Domain Architecture
Description	Ras-related protein Rab-10.

RAB10_MOUSE
NC score	0.010765 (rank : 172)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	161	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	P61027, O88386, Q9D7X6	Gene names	Rab10
Domain Architecture
Description	Ras-related protein Rab-10.

RAB15_MOUSE
NC score	0.010680 (rank : 173)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	161	Target Neighborhood Hits	284	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K386	Gene names	Rab15
Domain Architecture
Description	Ras-related protein Rab-15.

TRI32_MOUSE
NC score	0.010653 (rank : 174)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	161	Target Neighborhood Hits	271	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

BRD3_MOUSE
NC score	0.010264 (rank : 175)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	161	Target Neighborhood Hits	402	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

RAB13_HUMAN
NC score	0.008146 (rank : 176)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	161	Target Neighborhood Hits	286	Shared Neighborhood Hits	17
SwissProt Accessions	P51153, Q96GU4	Gene names	RAB13
Domain Architecture
Description	Ras-related protein Rab-13.

MINK1_MOUSE
NC score	0.007681 (rank : 177)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	161	Target Neighborhood Hits	1451	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_HUMAN
NC score	0.007662 (rank : 178)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	161	Target Neighborhood Hits	1477	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

TWST2_MOUSE
NC score	0.007296 (rank : 179)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	161	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_HUMAN
NC score	0.007281 (rank : 180)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	161	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

PTN2_MOUSE
NC score	0.006322 (rank : 181)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	161	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

GDIT_HUMAN
NC score	0.004579 (rank : 182)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	161	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q99819, Q4TT69, Q96S29	Gene names	ARHGDIG
Domain Architecture
Description	Rho GDP-dissociation inhibitor 3 (Rho GDI 3) (Rho-GDI gamma).

SUV91_MOUSE
NC score	0.004491 (rank : 183)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	161	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

UBP37_HUMAN
NC score	0.003453 (rank : 184)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	161	Target Neighborhood Hits	208	Shared Neighborhood Hits	15
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

CD2L1_MOUSE
NC score	0.002846 (rank : 185)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	161	Target Neighborhood Hits	1463	Shared Neighborhood Hits	61
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

NAL13_HUMAN
NC score	0.002554 (rank : 186)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	161	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

CD2L1_HUMAN
NC score	0.002507 (rank : 187)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	161	Target Neighborhood Hits	1467	Shared Neighborhood Hits	59
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

PP16A_MOUSE
NC score	-0.000514 (rank : 188)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	161	Target Neighborhood Hits	318	Shared Neighborhood Hits	2
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).