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Network neighborhood for query Sequence : RIR2_HUMAN

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RIR2_HUMAN
SwissProt Accessions	P31350, Q5WRU7	Gene names	RRM2, RR2
Domain Architecture
Description	Ribonucleoside-diphosphate reductase M2 subunit (EC 1.17.4.1) (Ribonucleotide reductase small subunit) (Ribonucleotide reductase small chain).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RIR2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	P31350, Q5WRU7	Gene names	RRM2, RR2
Domain Architecture
Description	Ribonucleoside-diphosphate reductase M2 subunit (EC 1.17.4.1) (Ribonucleotide reductase small subunit) (Ribonucleotide reductase small chain).

RIR2_MOUSE
θ value	0 (rank : 2)	NC score	0.998831 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	P11157, Q3UI23, Q542E2	Gene names	Rrm2
Domain Architecture
Description	Ribonucleoside-diphosphate reductase M2 subunit (EC 1.17.4.1) (Ribonucleotide reductase small subunit) (Ribonucleotide reductase small chain).

RIR2B_MOUSE
θ value	1.91371e-159 (rank : 3)	NC score	0.995795 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PEE3	Gene names	Rrm2b, P53r2
Domain Architecture	No domain graphic available
Description	Ribonucleoside-diphosphate reductase M2 subunit B (EC 1.17.4.1) (TP53- inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2).

RIR2B_HUMAN
θ value	5.96274e-153 (rank : 4)	NC score	0.995411 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q7LG56, Q75PQ6, Q75PQ7, Q75PY8, Q75PY9, Q86YE3, Q9NPD6, Q9NTD8, Q9NUW3	Gene names	RRM2B, P53R2
Domain Architecture	No domain graphic available
Description	Ribonucleoside-diphosphate reductase M2 subunit B (EC 1.17.4.1) (TP53- inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2).

ITB7_HUMAN
θ value	0.47712 (rank : 5)	NC score	0.022487 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	290	Shared Neighborhood Hits	4
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

TAF4_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.026639 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	687	Shared Neighborhood Hits	3
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ITB7_MOUSE
θ value	3.0926 (rank : 7)	NC score	0.017093 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	277	Shared Neighborhood Hits	3
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

INCE_HUMAN
θ value	6.88961 (rank : 8)	NC score	0.004823 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	978	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

DHB4_HUMAN
θ value	8.99809 (rank : 9)	NC score	0.007501 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	P51659	Gene names	HSD17B4, EDH17B4
Domain Architecture
Description	Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-3-hydroxyacyl-CoA dehydratase) (EC 4.2.1.107) (3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase) (3- hydroxyacyl-CoA dehydrogenase) (EC 1.1.1.35).

Hits sorted by NC score

RIR2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	P31350, Q5WRU7	Gene names	RRM2, RR2
Domain Architecture
Description	Ribonucleoside-diphosphate reductase M2 subunit (EC 1.17.4.1) (Ribonucleotide reductase small subunit) (Ribonucleotide reductase small chain).

RIR2_MOUSE
NC score	0.998831 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	P11157, Q3UI23, Q542E2	Gene names	Rrm2
Domain Architecture
Description	Ribonucleoside-diphosphate reductase M2 subunit (EC 1.17.4.1) (Ribonucleotide reductase small subunit) (Ribonucleotide reductase small chain).

RIR2B_MOUSE
NC score	0.995795 (rank : 3)	θ value	1.91371e-159 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PEE3	Gene names	Rrm2b, P53r2
Domain Architecture	No domain graphic available
Description	Ribonucleoside-diphosphate reductase M2 subunit B (EC 1.17.4.1) (TP53- inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2).

RIR2B_HUMAN
NC score	0.995411 (rank : 4)	θ value	5.96274e-153 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q7LG56, Q75PQ6, Q75PQ7, Q75PY8, Q75PY9, Q86YE3, Q9NPD6, Q9NTD8, Q9NUW3	Gene names	RRM2B, P53R2
Domain Architecture	No domain graphic available
Description	Ribonucleoside-diphosphate reductase M2 subunit B (EC 1.17.4.1) (TP53- inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2).

TAF4_HUMAN
NC score	0.026639 (rank : 5)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	687	Shared Neighborhood Hits	3
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ITB7_HUMAN
NC score	0.022487 (rank : 6)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	290	Shared Neighborhood Hits	4
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
NC score	0.017093 (rank : 7)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	277	Shared Neighborhood Hits	3
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

DHB4_HUMAN
NC score	0.007501 (rank : 8)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	P51659	Gene names	HSD17B4, EDH17B4
Domain Architecture
Description	Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-3-hydroxyacyl-CoA dehydratase) (EC 4.2.1.107) (3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase) (3- hydroxyacyl-CoA dehydrogenase) (EC 1.1.1.35).

INCE_HUMAN
NC score	0.004823 (rank : 9)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	978	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.