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Network neighborhood for query Sequence : PRGB_HUMAN

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PRGB_HUMAN
SwissProt Accessions	Q02325	Gene names	PLGL, PRGB
Domain Architecture
Description	Plasminogen-related protein B precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRGB_HUMAN
θ value	5.96599e-36 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	6	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	Q02325	Gene names	PLGL, PRGB
Domain Architecture
Description	Plasminogen-related protein B precursor.

PLMN_HUMAN
θ value	1.24399e-33 (rank : 2)	NC score	0.246510 (rank : 2)
Query Neighborhood Hits	6	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PLMN_MOUSE
θ value	7.54701e-31 (rank : 3)	NC score	0.244021 (rank : 3)
Query Neighborhood Hits	6	Target Neighborhood Hits	208	Shared Neighborhood Hits	5
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

HGF_HUMAN
θ value	0.62314 (rank : 4)	NC score	0.199178 (rank : 4)
Query Neighborhood Hits	6	Target Neighborhood Hits	191	Shared Neighborhood Hits	5
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

BAP29_HUMAN
θ value	3.0926 (rank : 5)	NC score	0.038022 (rank : 180)
Query Neighborhood Hits	6	Target Neighborhood Hits	362	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

HGF_MOUSE
θ value	4.03905 (rank : 6)	NC score	0.196779 (rank : 5)
Query Neighborhood Hits	6	Target Neighborhood Hits	192	Shared Neighborhood Hits	5
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

ACRO_HUMAN
θ value	θ > 10 (rank : 7)	NC score	0.102725 (rank : 54)
Query Neighborhood Hits	6	Target Neighborhood Hits	291	Shared Neighborhood Hits	4
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ACRO_MOUSE
θ value	θ > 10 (rank : 8)	NC score	0.104653 (rank : 42)
Query Neighborhood Hits	6	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

APOA_HUMAN
θ value	θ > 10 (rank : 9)	NC score	0.190519 (rank : 6)
Query Neighborhood Hits	6	Target Neighborhood Hits	221	Shared Neighborhood Hits	4
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

BSSP4_HUMAN
θ value	θ > 10 (rank : 10)	NC score	0.101466 (rank : 61)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

BSSP4_MOUSE
θ value	θ > 10 (rank : 11)	NC score	0.099605 (rank : 70)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

C1RA_MOUSE
θ value	θ > 10 (rank : 12)	NC score	0.079045 (rank : 171)
Query Neighborhood Hits	6	Target Neighborhood Hits	379	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 13)	NC score	0.078113 (rank : 172)
Query Neighborhood Hits	6	Target Neighborhood Hits	380	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 14)	NC score	0.077524 (rank : 173)
Query Neighborhood Hits	6	Target Neighborhood Hits	364	Shared Neighborhood Hits	4
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 15)	NC score	0.085253 (rank : 158)
Query Neighborhood Hits	6	Target Neighborhood Hits	359	Shared Neighborhood Hits	4
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CAP7_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.101030 (rank : 64)
Query Neighborhood Hits	6	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	P20160, P80014, Q52LG4	Gene names	AZU1
Domain Architecture
Description	Azurocidin precursor (Cationic antimicrobial protein CAP37) (Heparin- binding protein) (HBP).

CATG_HUMAN
θ value	θ > 10 (rank : 17)	NC score	0.091313 (rank : 117)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

CATG_MOUSE
θ value	θ > 10 (rank : 18)	NC score	0.096566 (rank : 90)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

CFAB_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.071290 (rank : 174)
Query Neighborhood Hits	6	Target Neighborhood Hits	251	Shared Neighborhood Hits	2
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.070602 (rank : 175)
Query Neighborhood Hits	6	Target Neighborhood Hits	262	Shared Neighborhood Hits	2
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAD_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.094298 (rank : 102)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

CFAD_MOUSE
θ value	θ > 10 (rank : 22)	NC score	0.094907 (rank : 97)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

CFAI_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.092152 (rank : 111)
Query Neighborhood Hits	6	Target Neighborhood Hits	289	Shared Neighborhood Hits	4
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_MOUSE
θ value	θ > 10 (rank : 24)	NC score	0.089131 (rank : 137)
Query Neighborhood Hits	6	Target Neighborhood Hits	290	Shared Neighborhood Hits	4
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CLCR_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.105086 (rank : 37)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

CO2_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.056916 (rank : 177)
Query Neighborhood Hits	6	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 27)	NC score	0.060499 (rank : 176)
Query Neighborhood Hits	6	Target Neighborhood Hits	250	Shared Neighborhood Hits	4
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CORIN_HUMAN
θ value	θ > 10 (rank : 28)	NC score	0.084970 (rank : 161)
Query Neighborhood Hits	6	Target Neighborhood Hits	453	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
θ value	θ > 10 (rank : 29)	NC score	0.085051 (rank : 160)
Query Neighborhood Hits	6	Target Neighborhood Hits	451	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CS1A_MOUSE
θ value	θ > 10 (rank : 30)	NC score	0.086709 (rank : 148)
Query Neighborhood Hits	6	Target Neighborhood Hits	360	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 31)	NC score	0.085501 (rank : 156)
Query Neighborhood Hits	6	Target Neighborhood Hits	361	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CTRB1_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.104254 (rank : 48)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

CTRL_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.105315 (rank : 34)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

DESC4_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.102263 (rank : 57)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

EGFB2_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.086423 (rank : 151)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

ELA1_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.107862 (rank : 24)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

ELA2A_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.105878 (rank : 32)
Query Neighborhood Hits	6	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

ELA2A_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.107599 (rank : 26)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

ELA2B_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.105990 (rank : 30)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

ELA3A_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.109802 (rank : 20)
Query Neighborhood Hits	6	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

ELA3B_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.110224 (rank : 19)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

ELNE_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.108865 (rank : 23)
Query Neighborhood Hits	6	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	P08246, P09649, Q6B0D9, Q6LDP5	Gene names	ELA2
Domain Architecture
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase) (PMN elastase) (Bone marrow serine protease) (Medullasin) (Human leukocyte elastase) (HLE).

ELNE_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.109514 (rank : 22)
Query Neighborhood Hits	6	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UP87, Q61515	Gene names	Ela2
Domain Architecture	No domain graphic available
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase).

ENTK_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.095022 (rank : 95)
Query Neighborhood Hits	6	Target Neighborhood Hits	310	Shared Neighborhood Hits	4
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ENTK_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.098441 (rank : 79)
Query Neighborhood Hits	6	Target Neighborhood Hits	338	Shared Neighborhood Hits	4
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

FA10_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.087999 (rank : 143)
Query Neighborhood Hits	6	Target Neighborhood Hits	431	Shared Neighborhood Hits	4
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.085088 (rank : 159)
Query Neighborhood Hits	6	Target Neighborhood Hits	435	Shared Neighborhood Hits	4
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA11_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.096652 (rank : 89)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA11_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.095550 (rank : 92)
Query Neighborhood Hits	6	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA12_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.107759 (rank : 25)
Query Neighborhood Hits	6	Target Neighborhood Hits	425	Shared Neighborhood Hits	4
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.094956 (rank : 96)
Query Neighborhood Hits	6	Target Neighborhood Hits	404	Shared Neighborhood Hits	4
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.091895 (rank : 113)
Query Neighborhood Hits	6	Target Neighborhood Hits	374	Shared Neighborhood Hits	4
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.085314 (rank : 157)
Query Neighborhood Hits	6	Target Neighborhood Hits	421	Shared Neighborhood Hits	4
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

GRAC_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.089639 (rank : 133)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P08882, Q61389	Gene names	Gzmc, Ctla-5, Ctla5
Domain Architecture
Description	Granzyme C precursor (EC 3.4.21.-) (Cytotoxic cell protease 2) (CCP2) (B10).

GRAD_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.093846 (rank : 103)
Query Neighborhood Hits	6	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

GRAE_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.097075 (rank : 86)
Query Neighborhood Hits	6	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	P08884, P97389	Gene names	Gzme, Ccp3, Ctla-6, Ctla6
Domain Architecture
Description	Granzyme E precursor (EC 3.4.21.-) (Cytotoxic cell protease 3) (CCP3) (CTL serine protease 2) (D12) (Cytotoxic serine protease 2) (MCSP2).

GRAF_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.097906 (rank : 82)
Query Neighborhood Hits	6	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	P08883	Gene names	Gzmf, Ccp4, Ctla-7, Ctla7
Domain Architecture
Description	Granzyme F precursor (EC 3.4.21.-) (Cytotoxic cell protease 4) (CCP4) (CTL serine protease 3) (C134) (Cytotoxic serine protease 3) (MCSP3).

GRAG_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.097275 (rank : 85)
Query Neighborhood Hits	6	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P13366, P97388	Gene names	Gzmg
Domain Architecture
Description	Granzyme G precursor (EC 3.4.21.-) (CTL serine protease 1) (MCSP-1).

GRAH_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.093620 (rank : 104)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

GRAK_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.101607 (rank : 59)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

GRAM_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.099204 (rank : 72)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

HABP2_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.104532 (rank : 44)
Query Neighborhood Hits	6	Target Neighborhood Hits	431	Shared Neighborhood Hits	4
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.104893 (rank : 39)
Query Neighborhood Hits	6	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HEPS_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.107208 (rank : 27)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.105045 (rank : 38)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HGFA_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.106654 (rank : 29)
Query Neighborhood Hits	6	Target Neighborhood Hits	436	Shared Neighborhood Hits	4
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.102900 (rank : 52)
Query Neighborhood Hits	6	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFL_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.190518 (rank : 7)
Query Neighborhood Hits	6	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGFL_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.188897 (rank : 8)
Query Neighborhood Hits	6	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HPTR_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.103337 (rank : 51)
Query Neighborhood Hits	6	Target Neighborhood Hits	166	Shared Neighborhood Hits	4
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.099173 (rank : 73)
Query Neighborhood Hits	6	Target Neighborhood Hits	184	Shared Neighborhood Hits	4
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPT_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.109583 (rank : 21)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

K1B11_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.089581 (rank : 135)
Query Neighborhood Hits	6	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

K1B16_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.080071 (rank : 170)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P04071	Gene names	Klk1b16, Klk-16, Klk16
Domain Architecture
Description	Kallikrein 1-related peptidase b16 precursor (EC 3.4.21.54) (Gamma- renin, submandibular gland) (mGK-16).

K1B21_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.089049 (rank : 138)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

K1B22_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.089796 (rank : 130)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

K1B24_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.089581 (rank : 134)
Query Neighborhood Hits	6	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

K1B26_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.086004 (rank : 155)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

K1B27_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.088406 (rank : 141)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

K1KB1_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.086234 (rank : 153)
Query Neighborhood Hits	6	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

K1KB3_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.089720 (rank : 131)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

K1KB4_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.086626 (rank : 149)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P00757	Gene names	Klk1b4, Klk-4, Klk4, Ngfa
Domain Architecture
Description	Kallikrein 1-related peptidase-like b4 precursor (7S nerve growth factor alpha chain) (Alpha-NGF).

K1KB5_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.086184 (rank : 154)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

K1KB8_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.087904 (rank : 144)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

K1KB9_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.089900 (rank : 128)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

KLK10_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.086787 (rank : 147)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK11_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.093415 (rank : 105)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

KLK11_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.095224 (rank : 94)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

KLK12_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.089345 (rank : 136)
Query Neighborhood Hits	6	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

KLK13_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.090745 (rank : 123)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KLK14_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.084302 (rank : 164)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK15_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.090746 (rank : 122)
Query Neighborhood Hits	6	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

KLK1_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.091178 (rank : 119)
Query Neighborhood Hits	6	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

KLK1_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.086427 (rank : 150)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

KLK2_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.092139 (rank : 112)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

KLK3_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.092666 (rank : 109)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P07288, Q16272, Q86TG8	Gene names	KLK3, APS
Domain Architecture
Description	Prostate-specific antigen precursor (EC 3.4.21.77) (PSA) (Kallikrein- 3) (Semenogelase) (Gamma-seminoprotein) (Seminin) (P-30 antigen).

KLK4_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.083248 (rank : 166)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

KLK5_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.088611 (rank : 140)
Query Neighborhood Hits	6	Target Neighborhood Hits	182	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

KLK6_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.091194 (rank : 118)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK7_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.082886 (rank : 168)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

KLK7_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.084617 (rank : 163)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK9_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.088801 (rank : 139)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

KLKB1_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.096298 (rank : 91)
Query Neighborhood Hits	6	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLKB1_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.098573 (rank : 78)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KREM1_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.141629 (rank : 10)
Query Neighborhood Hits	6	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.142444 (rank : 9)
Query Neighborhood Hits	6	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.133120 (rank : 12)
Query Neighborhood Hits	6	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.135624 (rank : 11)
Query Neighborhood Hits	6	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

MASP1_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.083587 (rank : 165)
Query Neighborhood Hits	6	Target Neighborhood Hits	369	Shared Neighborhood Hits	4
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.084892 (rank : 162)
Query Neighborhood Hits	6	Target Neighborhood Hits	364	Shared Neighborhood Hits	4
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.082035 (rank : 169)
Query Neighborhood Hits	6	Target Neighborhood Hits	364	Shared Neighborhood Hits	4
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.083175 (rank : 167)
Query Neighborhood Hits	6	Target Neighborhood Hits	382	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MCPT1_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.091549 (rank : 116)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P23946, Q16018	Gene names	CMA1, CYH, CYM
Domain Architecture
Description	Chymase precursor (EC 3.4.21.39) (Mast cell protease I).

MCPT1_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.090448 (rank : 126)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

MCPT2_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.090856 (rank : 120)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

MCPT4_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.090630 (rank : 124)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

MCPT5_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.092673 (rank : 108)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P21844, Q9R1F0	Gene names	Mcpt5
Domain Architecture
Description	Mast cell protease 5 precursor (EC 3.4.21.-) (MMCP-5) (Mast cell chymase 1).

MCPT6_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.100981 (rank : 65)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

MCPT8_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.086948 (rank : 146)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P43430, Q9R1F1	Gene names	Mcpt8
Domain Architecture
Description	Mast cell protease 8 precursor (EC 3.4.21.-) (MMCP-8).

MCPT9_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.096894 (rank : 87)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	O35164	Gene names	Mcpt9
Domain Architecture
Description	Mast cell protease 9 precursor (EC 3.4.21.-) (MMCP-9).

MCPTX_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.098638 (rank : 77)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q00356	Gene names	Mcptl
Domain Architecture
Description	Mast cell protease-like protein precursor (EC 3.4.21.-).

NETR_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.090509 (rank : 125)
Query Neighborhood Hits	6	Target Neighborhood Hits	218	Shared Neighborhood Hits	4
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

NETR_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.091605 (rank : 115)
Query Neighborhood Hits	6	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

NRPN_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.086349 (rank : 152)
Query Neighborhood Hits	6	Target Neighborhood Hits	182	Shared Neighborhood Hits	4
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

NRPN_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.089833 (rank : 129)
Query Neighborhood Hits	6	Target Neighborhood Hits	186	Shared Neighborhood Hits	4
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

POLS2_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.099988 (rank : 68)
Query Neighborhood Hits	6	Target Neighborhood Hits	192	Shared Neighborhood Hits	4
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

POLS2_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.099634 (rank : 69)
Query Neighborhood Hits	6	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

PROC_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.090338 (rank : 127)
Query Neighborhood Hits	6	Target Neighborhood Hits	406	Shared Neighborhood Hits	4
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.087036 (rank : 145)
Query Neighborhood Hits	6	Target Neighborhood Hits	426	Shared Neighborhood Hits	4
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROZ_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.055069 (rank : 178)
Query Neighborhood Hits	6	Target Neighborhood Hits	422	Shared Neighborhood Hits	4
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.053031 (rank : 179)
Query Neighborhood Hits	6	Target Neighborhood Hits	410	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PRS27_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.104765 (rank : 41)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRS27_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.104469 (rank : 45)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

PRSS8_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.098051 (rank : 81)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRSS8_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.099467 (rank : 71)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

PRTN3_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.102180 (rank : 58)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P24158, P15637, P18078, Q6LBM7, Q9UQD8	Gene names	PRTN3, MBN
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Leukocyte proteinase 3) (PR-3) (PR3) (AGP7) (Wegener autoantigen) (P29) (C-ANCA antigen) (Neutrophil proteinase 4) (NP-4).

PRTN3_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.106658 (rank : 28)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q61096, O08809	Gene names	Prtn3
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Proteinase 3) (PR-3).

ST14_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.089647 (rank : 132)
Query Neighborhood Hits	6	Target Neighborhood Hits	409	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.088362 (rank : 142)
Query Neighborhood Hits	6	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TEST_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.104426 (rank : 47)
Query Neighborhood Hits	6	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

TEST_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.105099 (rank : 36)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

THRB_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.130359 (rank : 14)
Query Neighborhood Hits	6	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.130777 (rank : 13)
Query Neighborhood Hits	6	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TM11D_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.097332 (rank : 84)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11D_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.097441 (rank : 83)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.098975 (rank : 74)
Query Neighborhood Hits	6	Target Neighborhood Hits	181	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TM11E_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.100746 (rank : 66)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS2_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.101402 (rank : 63)
Query Neighborhood Hits	6	Target Neighborhood Hits	252	Shared Neighborhood Hits	4
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.104432 (rank : 46)
Query Neighborhood Hits	6	Target Neighborhood Hits	243	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.103890 (rank : 50)
Query Neighborhood Hits	6	Target Neighborhood Hits	245	Shared Neighborhood Hits	4
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS3_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.104591 (rank : 43)
Query Neighborhood Hits	6	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS4_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.101488 (rank : 60)
Query Neighborhood Hits	6	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS4_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.104074 (rank : 49)
Query Neighborhood Hits	6	Target Neighborhood Hits	210	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS5_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.098052 (rank : 80)
Query Neighborhood Hits	6	Target Neighborhood Hits	181	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS5_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.096673 (rank : 88)
Query Neighborhood Hits	6	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS6_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.090812 (rank : 121)
Query Neighborhood Hits	6	Target Neighborhood Hits	338	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.093261 (rank : 107)
Query Neighborhood Hits	6	Target Neighborhood Hits	341	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.091834 (rank : 114)
Query Neighborhood Hits	6	Target Neighborhood Hits	275	Shared Neighborhood Hits	4
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.092232 (rank : 110)
Query Neighborhood Hits	6	Target Neighborhood Hits	275	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS9_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.094500 (rank : 100)
Query Neighborhood Hits	6	Target Neighborhood Hits	276	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.093298 (rank : 106)
Query Neighborhood Hits	6	Target Neighborhood Hits	296	Shared Neighborhood Hits	4
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TMPSD_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.102848 (rank : 53)
Query Neighborhood Hits	6	Target Neighborhood Hits	333	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.102297 (rank : 56)
Query Neighborhood Hits	6	Target Neighborhood Hits	334	Shared Neighborhood Hits	4
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMSP8_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.105859 (rank : 33)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TPA_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.127760 (rank : 16)
Query Neighborhood Hits	6	Target Neighborhood Hits	324	Shared Neighborhood Hits	4
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.128149 (rank : 15)
Query Neighborhood Hits	6	Target Neighborhood Hits	335	Shared Neighborhood Hits	4
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRY1_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.094464 (rank : 101)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

TRY2_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.094647 (rank : 98)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

TRY2_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.094565 (rank : 99)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

TRY3_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.095316 (rank : 93)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

TRYA1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.100607 (rank : 67)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

TRYB1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.098759 (rank : 75)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.105260 (rank : 35)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYB2_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.098759 (rank : 76)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRYD_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.101441 (rank : 62)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TRYG1_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.105886 (rank : 31)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TRYG1_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.102707 (rank : 55)
Query Neighborhood Hits	6	Target Neighborhood Hits	181	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TSP50_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.104776 (rank : 40)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

UROK_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.111059 (rank : 18)
Query Neighborhood Hits	6	Target Neighborhood Hits	272	Shared Neighborhood Hits	4
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROK_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.111709 (rank : 17)
Query Neighborhood Hits	6	Target Neighborhood Hits	273	Shared Neighborhood Hits	4
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

Hits sorted by NC score

PRGB_HUMAN
NC score	0.999962 (rank : 1)	θ value	5.96599e-36 (rank : 1)
Query Neighborhood Hits	6	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	Q02325	Gene names	PLGL, PRGB
Domain Architecture
Description	Plasminogen-related protein B precursor.

PLMN_HUMAN
NC score	0.246510 (rank : 2)	θ value	1.24399e-33 (rank : 2)
Query Neighborhood Hits	6	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PLMN_MOUSE
NC score	0.244021 (rank : 3)	θ value	7.54701e-31 (rank : 3)
Query Neighborhood Hits	6	Target Neighborhood Hits	208	Shared Neighborhood Hits	5
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

HGF_HUMAN
NC score	0.199178 (rank : 4)	θ value	0.62314 (rank : 4)
Query Neighborhood Hits	6	Target Neighborhood Hits	191	Shared Neighborhood Hits	5
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HGF_MOUSE
NC score	0.196779 (rank : 5)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	6	Target Neighborhood Hits	192	Shared Neighborhood Hits	5
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

APOA_HUMAN
NC score	0.190519 (rank : 6)	θ value	θ > 10 (rank : 9)
Query Neighborhood Hits	6	Target Neighborhood Hits	221	Shared Neighborhood Hits	4
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

HGFL_HUMAN
NC score	0.190518 (rank : 7)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	6	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGFL_MOUSE
NC score	0.188897 (rank : 8)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	6	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

KREM1_MOUSE
NC score	0.142444 (rank : 9)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	6	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_HUMAN
NC score	0.141629 (rank : 10)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	6	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_MOUSE
NC score	0.135624 (rank : 11)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	6	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_HUMAN
NC score	0.133120 (rank : 12)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	6	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

THRB_MOUSE
NC score	0.130777 (rank : 13)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	6	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_HUMAN
NC score	0.130359 (rank : 14)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	6	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TPA_MOUSE
NC score	0.128149 (rank : 15)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	6	Target Neighborhood Hits	335	Shared Neighborhood Hits	4
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_HUMAN
NC score	0.127760 (rank : 16)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	6	Target Neighborhood Hits	324	Shared Neighborhood Hits	4
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

UROK_MOUSE
NC score	0.111709 (rank : 17)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	6	Target Neighborhood Hits	273	Shared Neighborhood Hits	4
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROK_HUMAN
NC score	0.111059 (rank : 18)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	6	Target Neighborhood Hits	272	Shared Neighborhood Hits	4
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

ELA3B_HUMAN
NC score	0.110224 (rank : 19)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

ELA3A_HUMAN
NC score	0.109802 (rank : 20)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	6	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

HPT_MOUSE
NC score	0.109583 (rank : 21)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

ELNE_MOUSE
NC score	0.109514 (rank : 22)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	6	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UP87, Q61515	Gene names	Ela2
Domain Architecture	No domain graphic available
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase).

ELNE_HUMAN
NC score	0.108865 (rank : 23)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	6	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	P08246, P09649, Q6B0D9, Q6LDP5	Gene names	ELA2
Domain Architecture
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase) (PMN elastase) (Bone marrow serine protease) (Medullasin) (Human leukocyte elastase) (HLE).

ELA1_HUMAN
NC score	0.107862 (rank : 24)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

FA12_HUMAN
NC score	0.107759 (rank : 25)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	6	Target Neighborhood Hits	425	Shared Neighborhood Hits	4
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

ELA2A_MOUSE
NC score	0.107599 (rank : 26)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

HEPS_HUMAN
NC score	0.107208 (rank : 27)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

PRTN3_MOUSE
NC score	0.106658 (rank : 28)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q61096, O08809	Gene names	Prtn3
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Proteinase 3) (PR-3).

HGFA_HUMAN
NC score	0.106654 (rank : 29)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	6	Target Neighborhood Hits	436	Shared Neighborhood Hits	4
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ELA2B_HUMAN
NC score	0.105990 (rank : 30)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

TRYG1_HUMAN
NC score	0.105886 (rank : 31)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

ELA2A_HUMAN
NC score	0.105878 (rank : 32)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	6	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

TMSP8_MOUSE
NC score	0.105859 (rank : 33)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

CTRL_HUMAN
NC score	0.105315 (rank : 34)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

TRYB1_MOUSE
NC score	0.105260 (rank : 35)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TEST_MOUSE
NC score	0.105099 (rank : 36)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

CLCR_HUMAN
NC score	0.105086 (rank : 37)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

HEPS_MOUSE
NC score	0.105045 (rank : 38)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HABP2_MOUSE
NC score	0.104893 (rank : 39)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	6	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

TSP50_HUMAN
NC score	0.104776 (rank : 40)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

PRS27_HUMAN
NC score	0.104765 (rank : 41)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

ACRO_MOUSE
NC score	0.104653 (rank : 42)	θ value	θ > 10 (rank : 8)
Query Neighborhood Hits	6	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

TMPS3_MOUSE
NC score	0.104591 (rank : 43)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	6	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

HABP2_HUMAN
NC score	0.104532 (rank : 44)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	6	Target Neighborhood Hits	431	Shared Neighborhood Hits	4
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

PRS27_MOUSE
NC score	0.104469 (rank : 45)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

TMPS2_MOUSE
NC score	0.104432 (rank : 46)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	6	Target Neighborhood Hits	243	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TEST_HUMAN
NC score	0.104426 (rank : 47)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	6	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

CTRB1_HUMAN
NC score	0.104254 (rank : 48)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

TMPS4_MOUSE
NC score	0.104074 (rank : 49)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	6	Target Neighborhood Hits	210	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS3_HUMAN
NC score	0.103890 (rank : 50)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	6	Target Neighborhood Hits	245	Shared Neighborhood Hits	4
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

HPTR_HUMAN
NC score	0.103337 (rank : 51)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	6	Target Neighborhood Hits	166	Shared Neighborhood Hits	4
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HGFA_MOUSE
NC score	0.102900 (rank : 52)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	6	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

TMPSD_HUMAN
NC score	0.102848 (rank : 53)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	6	Target Neighborhood Hits	333	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

ACRO_HUMAN
NC score	0.102725 (rank : 54)	θ value	θ > 10 (rank : 7)
Query Neighborhood Hits	6	Target Neighborhood Hits	291	Shared Neighborhood Hits	4
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

TRYG1_MOUSE
NC score	0.102707 (rank : 55)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	6	Target Neighborhood Hits	181	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TMPSD_MOUSE
NC score	0.102297 (rank : 56)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	6	Target Neighborhood Hits	334	Shared Neighborhood Hits	4
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

DESC4_MOUSE
NC score	0.102263 (rank : 57)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

PRTN3_HUMAN
NC score	0.102180 (rank : 58)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P24158, P15637, P18078, Q6LBM7, Q9UQD8	Gene names	PRTN3, MBN
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Leukocyte proteinase 3) (PR-3) (PR3) (AGP7) (Wegener autoantigen) (P29) (C-ANCA antigen) (Neutrophil proteinase 4) (NP-4).

GRAK_MOUSE
NC score	0.101607 (rank : 59)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

TMPS4_HUMAN
NC score	0.101488 (rank : 60)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	6	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

BSSP4_HUMAN
NC score	0.101466 (rank : 61)	θ value	θ > 10 (rank : 10)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

TRYD_HUMAN
NC score	0.101441 (rank : 62)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TMPS2_HUMAN
NC score	0.101402 (rank : 63)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	6	Target Neighborhood Hits	252	Shared Neighborhood Hits	4
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

CAP7_HUMAN
NC score	0.101030 (rank : 64)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	6	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	P20160, P80014, Q52LG4	Gene names	AZU1
Domain Architecture
Description	Azurocidin precursor (Cationic antimicrobial protein CAP37) (Heparin- binding protein) (HBP).

MCPT6_MOUSE
NC score	0.100981 (rank : 65)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

TM11E_MOUSE
NC score	0.100746 (rank : 66)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TRYA1_HUMAN
NC score	0.100607 (rank : 67)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

POLS2_HUMAN
NC score	0.099988 (rank : 68)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	6	Target Neighborhood Hits	192	Shared Neighborhood Hits	4
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

POLS2_MOUSE
NC score	0.099634 (rank : 69)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	6	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

BSSP4_MOUSE
NC score	0.099605 (rank : 70)	θ value	θ > 10 (rank : 11)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

PRSS8_MOUSE
NC score	0.099467 (rank : 71)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

GRAM_HUMAN
NC score	0.099204 (rank : 72)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

HPT_HUMAN
NC score	0.099173 (rank : 73)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	6	Target Neighborhood Hits	184	Shared Neighborhood Hits	4
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

TM11E_HUMAN
NC score	0.098975 (rank : 74)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	6	Target Neighborhood Hits	181	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TRYB1_HUMAN
NC score	0.098759 (rank : 75)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB2_HUMAN
NC score	0.098759 (rank : 76)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

MCPTX_MOUSE
NC score	0.098638 (rank : 77)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q00356	Gene names	Mcptl
Domain Architecture
Description	Mast cell protease-like protein precursor (EC 3.4.21.-).

KLKB1_MOUSE
NC score	0.098573 (rank : 78)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

ENTK_MOUSE
NC score	0.098441 (rank : 79)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	6	Target Neighborhood Hits	338	Shared Neighborhood Hits	4
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TMPS5_HUMAN
NC score	0.098052 (rank : 80)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	6	Target Neighborhood Hits	181	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

PRSS8_HUMAN
NC score	0.098051 (rank : 81)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

GRAF_MOUSE
NC score	0.097906 (rank : 82)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	6	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	P08883	Gene names	Gzmf, Ccp4, Ctla-7, Ctla7
Domain Architecture
Description	Granzyme F precursor (EC 3.4.21.-) (Cytotoxic cell protease 4) (CCP4) (CTL serine protease 3) (C134) (Cytotoxic serine protease 3) (MCSP3).

TM11D_MOUSE
NC score	0.097441 (rank : 83)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11D_HUMAN
NC score	0.097332 (rank : 84)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

GRAG_MOUSE
NC score	0.097275 (rank : 85)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	6	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P13366, P97388	Gene names	Gzmg
Domain Architecture
Description	Granzyme G precursor (EC 3.4.21.-) (CTL serine protease 1) (MCSP-1).

GRAE_MOUSE
NC score	0.097075 (rank : 86)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	6	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	P08884, P97389	Gene names	Gzme, Ccp3, Ctla-6, Ctla6
Domain Architecture
Description	Granzyme E precursor (EC 3.4.21.-) (Cytotoxic cell protease 3) (CCP3) (CTL serine protease 2) (D12) (Cytotoxic serine protease 2) (MCSP2).

MCPT9_MOUSE
NC score	0.096894 (rank : 87)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	O35164	Gene names	Mcpt9
Domain Architecture
Description	Mast cell protease 9 precursor (EC 3.4.21.-) (MMCP-9).

TMPS5_MOUSE
NC score	0.096673 (rank : 88)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	6	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

FA11_HUMAN
NC score	0.096652 (rank : 89)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

CATG_MOUSE
NC score	0.096566 (rank : 90)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

KLKB1_HUMAN
NC score	0.096298 (rank : 91)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	6	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

FA11_MOUSE
NC score	0.095550 (rank : 92)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	6	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

TRY3_HUMAN
NC score	0.095316 (rank : 93)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

KLK11_MOUSE
NC score	0.095224 (rank : 94)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

ENTK_HUMAN
NC score	0.095022 (rank : 95)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	6	Target Neighborhood Hits	310	Shared Neighborhood Hits	4
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

FA7_HUMAN
NC score	0.094956 (rank : 96)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	6	Target Neighborhood Hits	404	Shared Neighborhood Hits	4
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

CFAD_MOUSE
NC score	0.094907 (rank : 97)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

TRY2_HUMAN
NC score	0.094647 (rank : 98)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

TRY2_MOUSE
NC score	0.094565 (rank : 99)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

TMPS9_HUMAN
NC score	0.094500 (rank : 100)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	6	Target Neighborhood Hits	276	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TRY1_HUMAN
NC score	0.094464 (rank : 101)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

CFAD_HUMAN
NC score	0.094298 (rank : 102)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

GRAD_MOUSE
NC score	0.093846 (rank : 103)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	6	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

GRAH_HUMAN
NC score	0.093620 (rank : 104)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

KLK11_HUMAN
NC score	0.093415 (rank : 105)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

TMPS9_MOUSE
NC score	0.093298 (rank : 106)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	6	Target Neighborhood Hits	296	Shared Neighborhood Hits	4
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TMPS6_MOUSE
NC score	0.093261 (rank : 107)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	6	Target Neighborhood Hits	341	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

MCPT5_MOUSE
NC score	0.092673 (rank : 108)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P21844, Q9R1F0	Gene names	Mcpt5
Domain Architecture
Description	Mast cell protease 5 precursor (EC 3.4.21.-) (MMCP-5) (Mast cell chymase 1).

KLK3_HUMAN
NC score	0.092666 (rank : 109)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P07288, Q16272, Q86TG8	Gene names	KLK3, APS
Domain Architecture
Description	Prostate-specific antigen precursor (EC 3.4.21.77) (PSA) (Kallikrein- 3) (Semenogelase) (Gamma-seminoprotein) (Seminin) (P-30 antigen).

TMPS7_MOUSE
NC score	0.092232 (rank : 110)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	6	Target Neighborhood Hits	275	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

CFAI_HUMAN
NC score	0.092152 (rank : 111)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	6	Target Neighborhood Hits	289	Shared Neighborhood Hits	4
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

KLK2_HUMAN
NC score	0.092139 (rank : 112)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

FA7_MOUSE
NC score	0.091895 (rank : 113)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	6	Target Neighborhood Hits	374	Shared Neighborhood Hits	4
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

TMPS7_HUMAN
NC score	0.091834 (rank : 114)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	6	Target Neighborhood Hits	275	Shared Neighborhood Hits	4
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

NETR_MOUSE
NC score	0.091605 (rank : 115)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	6	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

MCPT1_HUMAN
NC score	0.091549 (rank : 116)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P23946, Q16018	Gene names	CMA1, CYH, CYM
Domain Architecture
Description	Chymase precursor (EC 3.4.21.39) (Mast cell protease I).

CATG_HUMAN
NC score	0.091313 (rank : 117)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

KLK6_HUMAN
NC score	0.091194 (rank : 118)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK1_HUMAN
NC score	0.091178 (rank : 119)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	6	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

MCPT2_MOUSE
NC score	0.090856 (rank : 120)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

TMPS6_HUMAN
NC score	0.090812 (rank : 121)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	6	Target Neighborhood Hits	338	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

KLK15_HUMAN
NC score	0.090746 (rank : 122)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	6	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

KLK13_HUMAN
NC score	0.090745 (rank : 123)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

MCPT4_MOUSE
NC score	0.090630 (rank : 124)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

NETR_HUMAN
NC score	0.090509 (rank : 125)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	6	Target Neighborhood Hits	218	Shared Neighborhood Hits	4
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

MCPT1_MOUSE
NC score	0.090448 (rank : 126)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

PROC_HUMAN
NC score	0.090338 (rank : 127)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	6	Target Neighborhood Hits	406	Shared Neighborhood Hits	4
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

K1KB9_MOUSE
NC score	0.089900 (rank : 128)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

NRPN_MOUSE
NC score	0.089833 (rank : 129)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	6	Target Neighborhood Hits	186	Shared Neighborhood Hits	4
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

K1B22_MOUSE
NC score	0.089796 (rank : 130)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	6	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

K1KB3_MOUSE
NC score	0.089720 (rank : 131)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

ST14_HUMAN
NC score	0.089647 (rank : 132)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	6	Target Neighborhood Hits	409	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

GRAC_MOUSE
NC score	0.089639 (rank : 133)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P08882, Q61389	Gene names	Gzmc, Ctla-5, Ctla5
Domain Architecture
Description	Granzyme C precursor (EC 3.4.21.-) (Cytotoxic cell protease 2) (CCP2) (B10).

K1B24_MOUSE
NC score	0.089581 (rank : 134)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	6	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

K1B11_MOUSE
NC score	0.089581 (rank : 135)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	6	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

KLK12_HUMAN
NC score	0.089345 (rank : 136)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	6	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

CFAI_MOUSE
NC score	0.089131 (rank : 137)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	6	Target Neighborhood Hits	290	Shared Neighborhood Hits	4
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

K1B21_MOUSE
NC score	0.089049 (rank : 138)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

KLK9_HUMAN
NC score	0.088801 (rank : 139)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

KLK5_HUMAN
NC score	0.088611 (rank : 140)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	6	Target Neighborhood Hits	182	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

K1B27_MOUSE
NC score	0.088406 (rank : 141)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

ST14_MOUSE
NC score	0.088362 (rank : 142)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	6	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

FA10_HUMAN
NC score	0.087999 (rank : 143)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	6	Target Neighborhood Hits	431	Shared Neighborhood Hits	4
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

K1KB8_MOUSE
NC score	0.087904 (rank : 144)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

PROC_MOUSE
NC score	0.087036 (rank : 145)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	6	Target Neighborhood Hits	426	Shared Neighborhood Hits	4
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

MCPT8_MOUSE
NC score	0.086948 (rank : 146)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P43430, Q9R1F1	Gene names	Mcpt8
Domain Architecture
Description	Mast cell protease 8 precursor (EC 3.4.21.-) (MMCP-8).

KLK10_HUMAN
NC score	0.086787 (rank : 147)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

CS1A_MOUSE
NC score	0.086709 (rank : 148)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	6	Target Neighborhood Hits	360	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

K1KB4_MOUSE
NC score	0.086626 (rank : 149)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P00757	Gene names	Klk1b4, Klk-4, Klk4, Ngfa
Domain Architecture
Description	Kallikrein 1-related peptidase-like b4 precursor (7S nerve growth factor alpha chain) (Alpha-NGF).

KLK1_MOUSE
NC score	0.086427 (rank : 150)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

EGFB2_MOUSE
NC score	0.086423 (rank : 151)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	6	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

NRPN_HUMAN
NC score	0.086349 (rank : 152)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	6	Target Neighborhood Hits	182	Shared Neighborhood Hits	4
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

K1KB1_MOUSE
NC score	0.086234 (rank : 153)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	6	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

K1KB5_MOUSE
NC score	0.086184 (rank : 154)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

K1B26_MOUSE
NC score	0.086004 (rank : 155)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	6	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

CS1B_MOUSE
NC score	0.085501 (rank : 156)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	6	Target Neighborhood Hits	361	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

FA9_HUMAN
NC score	0.085314 (rank : 157)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	6	Target Neighborhood Hits	421	Shared Neighborhood Hits	4
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

C1S_HUMAN
NC score	0.085253 (rank : 158)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	6	Target Neighborhood Hits	359	Shared Neighborhood Hits	4
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

FA10_MOUSE
NC score	0.085088 (rank : 159)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	6	Target Neighborhood Hits	435	Shared Neighborhood Hits	4
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

CORIN_MOUSE
NC score	0.085051 (rank : 160)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	6	Target Neighborhood Hits	451	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CORIN_HUMAN
NC score	0.084970 (rank : 161)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	6	Target Neighborhood Hits	453	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

MASP1_MOUSE
NC score	0.084892 (rank : 162)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	6	Target Neighborhood Hits	364	Shared Neighborhood Hits	4
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

KLK7_MOUSE
NC score	0.084617 (rank : 163)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK14_HUMAN
NC score	0.084302 (rank : 164)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	6	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

MASP1_HUMAN
NC score	0.083587 (rank : 165)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	6	Target Neighborhood Hits	369	Shared Neighborhood Hits	4
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

KLK4_HUMAN
NC score	0.083248 (rank : 166)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

MASP2_MOUSE
NC score	0.083175 (rank : 167)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	6	Target Neighborhood Hits	382	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

KLK7_HUMAN
NC score	0.082886 (rank : 168)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	6	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

MASP2_HUMAN
NC score	0.082035 (rank : 169)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	6	Target Neighborhood Hits	364	Shared Neighborhood Hits	4
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

K1B16_MOUSE
NC score	0.080071 (rank : 170)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	6	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P04071	Gene names	Klk1b16, Klk-16, Klk16
Domain Architecture
Description	Kallikrein 1-related peptidase b16 precursor (EC 3.4.21.54) (Gamma- renin, submandibular gland) (mGK-16).

C1RA_MOUSE
NC score	0.079045 (rank : 171)	θ value	θ > 10 (rank : 12)
Query Neighborhood Hits	6	Target Neighborhood Hits	379	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
NC score	0.078113 (rank : 172)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	6	Target Neighborhood Hits	380	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
NC score	0.077524 (rank : 173)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	6	Target Neighborhood Hits	364	Shared Neighborhood Hits	4
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

CFAB_HUMAN
NC score	0.071290 (rank : 174)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	6	Target Neighborhood Hits	251	Shared Neighborhood Hits	2
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
NC score	0.070602 (rank : 175)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	6	Target Neighborhood Hits	262	Shared Neighborhood Hits	2
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO2_MOUSE
NC score	0.060499 (rank : 176)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	6	Target Neighborhood Hits	250	Shared Neighborhood Hits	4
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_HUMAN
NC score	0.056916 (rank : 177)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	6	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

PROZ_HUMAN
NC score	0.055069 (rank : 178)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	6	Target Neighborhood Hits	422	Shared Neighborhood Hits	4
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
NC score	0.053031 (rank : 179)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	6	Target Neighborhood Hits	410	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

BAP29_HUMAN
NC score	0.038022 (rank : 180)	θ value	3.0926 (rank : 5)
Query Neighborhood Hits	6	Target Neighborhood Hits	362	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).