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Network neighborhood for query Sequence : PEX2_HUMAN

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PEX2_HUMAN
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PEX2_HUMAN
θ value	1.11414e-183 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

PEX2_MOUSE
θ value	3.1544e-162 (rank : 2)	NC score	0.994238 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	57	Shared Neighborhood Hits	38
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

RN125_MOUSE
θ value	0.0330416 (rank : 3)	NC score	0.158443 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	220	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN146_HUMAN
θ value	0.0736092 (rank : 4)	NC score	0.185040 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	162	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	0.0736092 (rank : 5)	NC score	0.184350 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	161	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

TRI38_HUMAN
θ value	0.0961366 (rank : 6)	NC score	0.071304 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	373	Shared Neighborhood Hits	31
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

PCGF2_HUMAN
θ value	0.163984 (rank : 7)	NC score	0.157126 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	222	Shared Neighborhood Hits	27
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	0.163984 (rank : 8)	NC score	0.157236 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	213	Shared Neighborhood Hits	27
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

SMRA3_MOUSE
θ value	0.163984 (rank : 9)	NC score	0.112121 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	267	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

UHRF1_MOUSE
θ value	0.21417 (rank : 10)	NC score	0.123437 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	278	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

RNF8_MOUSE
θ value	0.279714 (rank : 11)	NC score	0.117833 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	618	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

SMRA3_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.108591 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	265	Shared Neighborhood Hits	36
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

PCGF6_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.162460 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	178	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	0.365318 (rank : 14)	NC score	0.163560 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

RN125_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.140260 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	230	Shared Neighborhood Hits	34
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRI60_HUMAN
θ value	0.365318 (rank : 16)	NC score	0.072601 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	357	Shared Neighborhood Hits	37
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

UHRF1_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.107769 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	272	Shared Neighborhood Hits	35
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

ZN645_HUMAN
θ value	1.06291 (rank : 18)	NC score	0.082254 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	265	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

TRI41_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.063195 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	349	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

PCGF4_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.138588 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	161	Shared Neighborhood Hits	28
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	1.81305 (rank : 21)	NC score	0.138798 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

UHRF2_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.108464 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	269	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.108937 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	275	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

BRCA1_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.094547 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	381	Shared Neighborhood Hits	36
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.090231 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	436	Shared Neighborhood Hits	35
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

RNF8_HUMAN
θ value	2.36792 (rank : 26)	NC score	0.105837 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	622	Shared Neighborhood Hits	38
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRIM5_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.065407 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	424	Shared Neighborhood Hits	35
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

BFAR_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.093204 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	232	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRAF5_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.056885 (rank : 50)
Query Neighborhood Hits	42	Target Neighborhood Hits	396	Shared Neighborhood Hits	26
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRI68_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.057722 (rank : 48)
Query Neighborhood Hits	42	Target Neighborhood Hits	356	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

CLK3_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.007381 (rank : 77)
Query Neighborhood Hits	42	Target Neighborhood Hits	748	Shared Neighborhood Hits	3
SwissProt Accessions	P49761, Q9BRS3, Q9BUJ7	Gene names	CLK3
Domain Architecture
Description	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3).

CLK3_MOUSE
θ value	4.03905 (rank : 32)	NC score	0.007465 (rank : 76)
Query Neighborhood Hits	42	Target Neighborhood Hits	761	Shared Neighborhood Hits	3
SwissProt Accessions	O35492	Gene names	Clk3
Domain Architecture
Description	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3).

TRAF5_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.057441 (rank : 49)
Query Neighborhood Hits	42	Target Neighborhood Hits	355	Shared Neighborhood Hits	26
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

RFWD2_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.060973 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	518	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.065258 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	535	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TRIM6_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.060303 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	451	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

SRP68_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.019653 (rank : 75)
Query Neighborhood Hits	42	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHB9, Q8NCJ4, Q8WUK2	Gene names	SRP68
Domain Architecture	No domain graphic available
Description	Signal recognition particle 68 kDa protein (SRP68).

TRI22_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.061351 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	396	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI31_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.073941 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	299	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

RKHD1_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.031964 (rank : 74)
Query Neighborhood Hits	42	Target Neighborhood Hits	163	Shared Neighborhood Hits	13
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RN168_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.076259 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	370	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI34_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.050849 (rank : 69)
Query Neighborhood Hits	42	Target Neighborhood Hits	332	Shared Neighborhood Hits	29
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

BFAR_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.079779 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	222	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

CHFR_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.050403 (rank : 71)
Query Neighborhood Hits	42	Target Neighborhood Hits	264	Shared Neighborhood Hits	32
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

PEX10_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.058690 (rank : 46)
Query Neighborhood Hits	42	Target Neighborhood Hits	255	Shared Neighborhood Hits	33
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

R113A_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.051939 (rank : 67)
Query Neighborhood Hits	42	Target Neighborhood Hits	177	Shared Neighborhood Hits	29
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RAG1_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.059627 (rank : 44)
Query Neighborhood Hits	42	Target Neighborhood Hits	203	Shared Neighborhood Hits	35
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.056884 (rank : 51)
Query Neighborhood Hits	42	Target Neighborhood Hits	189	Shared Neighborhood Hits	35
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RING1_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.062446 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	219	Shared Neighborhood Hits	32
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.061264 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	220	Shared Neighborhood Hits	32
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.059846 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	201	Shared Neighborhood Hits	32
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.059840 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	199	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN166_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.055604 (rank : 57)
Query Neighborhood Hits	42	Target Neighborhood Hits	240	Shared Neighborhood Hits	29
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.056662 (rank : 52)
Query Neighborhood Hits	42	Target Neighborhood Hits	248	Shared Neighborhood Hits	29
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN168_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.063892 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	440	Shared Neighborhood Hits	29
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RO52_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.051127 (rank : 68)
Query Neighborhood Hits	42	Target Neighborhood Hits	419	Shared Neighborhood Hits	37
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

RO52_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.052327 (rank : 65)
Query Neighborhood Hits	42	Target Neighborhood Hits	360	Shared Neighborhood Hits	37
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI11_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.053768 (rank : 59)
Query Neighborhood Hits	42	Target Neighborhood Hits	316	Shared Neighborhood Hits	37
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.053006 (rank : 63)
Query Neighborhood Hits	42	Target Neighborhood Hits	329	Shared Neighborhood Hits	37
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI12_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.060725 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	387	Shared Neighborhood Hits	35
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI25_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.052233 (rank : 66)
Query Neighborhood Hits	42	Target Neighborhood Hits	446	Shared Neighborhood Hits	34
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI26_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.056114 (rank : 54)
Query Neighborhood Hits	42	Target Neighborhood Hits	335	Shared Neighborhood Hits	37
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.055767 (rank : 56)
Query Neighborhood Hits	42	Target Neighborhood Hits	339	Shared Neighborhood Hits	36
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI30_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.056443 (rank : 53)
Query Neighborhood Hits	42	Target Neighborhood Hits	434	Shared Neighborhood Hits	35
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI34_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.050559 (rank : 70)
Query Neighborhood Hits	42	Target Neighborhood Hits	416	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI35_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.055861 (rank : 55)
Query Neighborhood Hits	42	Target Neighborhood Hits	382	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI39_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.050070 (rank : 73)
Query Neighborhood Hits	42	Target Neighborhood Hits	693	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.050373 (rank : 72)
Query Neighborhood Hits	42	Target Neighborhood Hits	691	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI40_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.058624 (rank : 47)
Query Neighborhood Hits	42	Target Neighborhood Hits	279	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI43_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.054995 (rank : 58)
Query Neighborhood Hits	42	Target Neighborhood Hits	341	Shared Neighborhood Hits	36
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI52_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.059521 (rank : 45)
Query Neighborhood Hits	42	Target Neighborhood Hits	213	Shared Neighborhood Hits	33
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI65_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.052759 (rank : 64)
Query Neighborhood Hits	42	Target Neighborhood Hits	340	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI73_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.053767 (rank : 60)
Query Neighborhood Hits	42	Target Neighborhood Hits	258	Shared Neighborhood Hits	35
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.053337 (rank : 61)
Query Neighborhood Hits	42	Target Neighborhood Hits	249	Shared Neighborhood Hits	35
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM6_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.053228 (rank : 62)
Query Neighborhood Hits	42	Target Neighborhood Hits	412	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

ZN313_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.061305 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	264	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.060451 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	273	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

Hits sorted by NC score

PEX2_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.11414e-183 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

PEX2_MOUSE
NC score	0.994238 (rank : 2)	θ value	3.1544e-162 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	57	Shared Neighborhood Hits	38
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

RN146_HUMAN
NC score	0.185040 (rank : 3)	θ value	0.0736092 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	162	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
NC score	0.184350 (rank : 4)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	161	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

PCGF6_MOUSE
NC score	0.163560 (rank : 5)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_HUMAN
NC score	0.162460 (rank : 6)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	178	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

RN125_MOUSE
NC score	0.158443 (rank : 7)	θ value	0.0330416 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	220	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

PCGF2_MOUSE
NC score	0.157236 (rank : 8)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	213	Shared Neighborhood Hits	27
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF2_HUMAN
NC score	0.157126 (rank : 9)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	222	Shared Neighborhood Hits	27
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

RN125_HUMAN
NC score	0.140260 (rank : 10)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	230	Shared Neighborhood Hits	34
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

PCGF4_MOUSE
NC score	0.138798 (rank : 11)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF4_HUMAN
NC score	0.138588 (rank : 12)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	161	Shared Neighborhood Hits	28
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

UHRF1_MOUSE
NC score	0.123437 (rank : 13)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	278	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

RNF8_MOUSE
NC score	0.117833 (rank : 14)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	618	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

SMRA3_MOUSE
NC score	0.112121 (rank : 15)	θ value	0.163984 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	267	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

UHRF2_MOUSE
NC score	0.108937 (rank : 16)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	275	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

SMRA3_HUMAN
NC score	0.108591 (rank : 17)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	265	Shared Neighborhood Hits	36
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

UHRF2_HUMAN
NC score	0.108464 (rank : 18)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	269	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF1_HUMAN
NC score	0.107769 (rank : 19)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	272	Shared Neighborhood Hits	35
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

RNF8_HUMAN
NC score	0.105837 (rank : 20)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	622	Shared Neighborhood Hits	38
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

BRCA1_HUMAN
NC score	0.094547 (rank : 21)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	381	Shared Neighborhood Hits	36
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BFAR_MOUSE
NC score	0.093204 (rank : 22)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	232	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BRCA1_MOUSE
NC score	0.090231 (rank : 23)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	436	Shared Neighborhood Hits	35
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

ZN645_HUMAN
NC score	0.082254 (rank : 24)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	265	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

BFAR_HUMAN
NC score	0.079779 (rank : 25)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	222	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

RN168_HUMAN
NC score	0.076259 (rank : 26)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	370	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI31_HUMAN
NC score	0.073941 (rank : 27)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	299	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI60_HUMAN
NC score	0.072601 (rank : 28)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	357	Shared Neighborhood Hits	37
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI38_HUMAN
NC score	0.071304 (rank : 29)	θ value	0.0961366 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	373	Shared Neighborhood Hits	31
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRIM5_HUMAN
NC score	0.065407 (rank : 30)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	424	Shared Neighborhood Hits	35
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

RFWD2_MOUSE
NC score	0.065258 (rank : 31)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	535	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RN168_MOUSE
NC score	0.063892 (rank : 32)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	42	Target Neighborhood Hits	440	Shared Neighborhood Hits	29
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI41_HUMAN
NC score	0.063195 (rank : 33)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	349	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

RING1_HUMAN
NC score	0.062446 (rank : 34)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	42	Target Neighborhood Hits	219	Shared Neighborhood Hits	32
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

TRI22_HUMAN
NC score	0.061351 (rank : 35)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	396	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

ZN313_HUMAN
NC score	0.061305 (rank : 36)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	42	Target Neighborhood Hits	264	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

RING1_MOUSE
NC score	0.061264 (rank : 37)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	42	Target Neighborhood Hits	220	Shared Neighborhood Hits	32
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RFWD2_HUMAN
NC score	0.060973 (rank : 38)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	518	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

TRI12_MOUSE
NC score	0.060725 (rank : 39)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	42	Target Neighborhood Hits	387	Shared Neighborhood Hits	35
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

ZN313_MOUSE
NC score	0.060451 (rank : 40)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	42	Target Neighborhood Hits	273	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

TRIM6_MOUSE
NC score	0.060303 (rank : 41)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	451	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

RING2_HUMAN
NC score	0.059846 (rank : 42)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	42	Target Neighborhood Hits	201	Shared Neighborhood Hits	32
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
NC score	0.059840 (rank : 43)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	42	Target Neighborhood Hits	199	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RAG1_HUMAN
NC score	0.059627 (rank : 44)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	42	Target Neighborhood Hits	203	Shared Neighborhood Hits	35
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

TRI52_HUMAN
NC score	0.059521 (rank : 45)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	42	Target Neighborhood Hits	213	Shared Neighborhood Hits	33
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

PEX10_HUMAN
NC score	0.058690 (rank : 46)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	42	Target Neighborhood Hits	255	Shared Neighborhood Hits	33
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TRI40_HUMAN
NC score	0.058624 (rank : 47)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	42	Target Neighborhood Hits	279	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI68_MOUSE
NC score	0.057722 (rank : 48)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	356	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRAF5_MOUSE
NC score	0.057441 (rank : 49)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	355	Shared Neighborhood Hits	26
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAF5_HUMAN
NC score	0.056885 (rank : 50)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	396	Shared Neighborhood Hits	26
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

RAG1_MOUSE
NC score	0.056884 (rank : 51)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	42	Target Neighborhood Hits	189	Shared Neighborhood Hits	35
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RN166_MOUSE
NC score	0.056662 (rank : 52)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	42	Target Neighborhood Hits	248	Shared Neighborhood Hits	29
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI30_MOUSE
NC score	0.056443 (rank : 53)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	42	Target Neighborhood Hits	434	Shared Neighborhood Hits	35
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI26_HUMAN
NC score	0.056114 (rank : 54)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	42	Target Neighborhood Hits	335	Shared Neighborhood Hits	37
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI35_HUMAN
NC score	0.055861 (rank : 55)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	42	Target Neighborhood Hits	382	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI26_MOUSE
NC score	0.055767 (rank : 56)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	42	Target Neighborhood Hits	339	Shared Neighborhood Hits	36
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

RN166_HUMAN
NC score	0.055604 (rank : 57)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	42	Target Neighborhood Hits	240	Shared Neighborhood Hits	29
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI43_HUMAN
NC score	0.054995 (rank : 58)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	42	Target Neighborhood Hits	341	Shared Neighborhood Hits	36
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI11_HUMAN
NC score	0.053768 (rank : 59)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	42	Target Neighborhood Hits	316	Shared Neighborhood Hits	37
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI73_HUMAN
NC score	0.053767 (rank : 60)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	42	Target Neighborhood Hits	258	Shared Neighborhood Hits	35
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
NC score	0.053337 (rank : 61)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	42	Target Neighborhood Hits	249	Shared Neighborhood Hits	35
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM6_HUMAN
NC score	0.053228 (rank : 62)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	42	Target Neighborhood Hits	412	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI11_MOUSE
NC score	0.053006 (rank : 63)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	42	Target Neighborhood Hits	329	Shared Neighborhood Hits	37
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI65_MOUSE
NC score	0.052759 (rank : 64)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	42	Target Neighborhood Hits	340	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RO52_MOUSE
NC score	0.052327 (rank : 65)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	42	Target Neighborhood Hits	360	Shared Neighborhood Hits	37
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI25_MOUSE
NC score	0.052233 (rank : 66)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	42	Target Neighborhood Hits	446	Shared Neighborhood Hits	34
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

R113A_HUMAN
NC score	0.051939 (rank : 67)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	42	Target Neighborhood Hits	177	Shared Neighborhood Hits	29
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RO52_HUMAN
NC score	0.051127 (rank : 68)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	42	Target Neighborhood Hits	419	Shared Neighborhood Hits	37
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI34_MOUSE
NC score	0.050849 (rank : 69)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	332	Shared Neighborhood Hits	29
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI34_HUMAN
NC score	0.050559 (rank : 70)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	42	Target Neighborhood Hits	416	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

CHFR_MOUSE
NC score	0.050403 (rank : 71)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	42	Target Neighborhood Hits	264	Shared Neighborhood Hits	32
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI39_MOUSE
NC score	0.050373 (rank : 72)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	42	Target Neighborhood Hits	691	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_HUMAN
NC score	0.050070 (rank : 73)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	42	Target Neighborhood Hits	693	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RKHD1_HUMAN
NC score	0.031964 (rank : 74)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	163	Shared Neighborhood Hits	13
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

SRP68_HUMAN
NC score	0.019653 (rank : 75)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHB9, Q8NCJ4, Q8WUK2	Gene names	SRP68
Domain Architecture	No domain graphic available
Description	Signal recognition particle 68 kDa protein (SRP68).

CLK3_MOUSE
NC score	0.007465 (rank : 76)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	761	Shared Neighborhood Hits	3
SwissProt Accessions	O35492	Gene names	Clk3
Domain Architecture
Description	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3).

CLK3_HUMAN
NC score	0.007381 (rank : 77)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	748	Shared Neighborhood Hits	3
SwissProt Accessions	P49761, Q9BRS3, Q9BUJ7	Gene names	CLK3
Domain Architecture
Description	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3).