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Network neighborhood for query Sequence : NRBP2_HUMAN

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NRBP2_HUMAN
SwissProt Accessions	Q9NSY0, Q597G7, Q8NCX8, Q8WYS5	Gene names	NRBP2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein 2 (Transformation-related protein 16).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NRBP2_HUMAN
θ value	1.62758e-142 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NSY0, Q597G7, Q8NCX8, Q8WYS5	Gene names	NRBP2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein 2 (Transformation-related protein 16).

NRBP2_MOUSE
θ value	5.23575e-141 (rank : 2)	NC score	0.998039 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q91V36, Q8R3M0	Gene names	Nrbp2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein 2.

NRBP_MOUSE
θ value	2.93355e-67 (rank : 3)	NC score	0.493456 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	442	Shared Neighborhood Hits	16
SwissProt Accessions	Q99J45, Q8BL77	Gene names	Nrbp1, Madm, Nrbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein (MLF1 adapter molecule) (HLS7- interacting protein kinase).

NRBP_HUMAN
θ value	5.00389e-67 (rank : 4)	NC score	0.492834 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	448	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHY1, Q53FZ5, Q96SU3	Gene names	NRBP1, BCON3, NRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein.

OXSR1_MOUSE
θ value	0.000786445 (rank : 5)	NC score	0.056193 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	865	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

OXSR1_HUMAN
θ value	0.0961366 (rank : 6)	NC score	0.048062 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	874	Shared Neighborhood Hits	20
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

STAB1_MOUSE
θ value	0.813845 (rank : 7)	NC score	0.018310 (rank : 27)
Query Neighborhood Hits	22	Target Neighborhood Hits	566	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

MST4_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.038941 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	852	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P289, Q3ZB77, Q9BXC4	Gene names	MST4, MASK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase).

MST4_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.039060 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	860	Shared Neighborhood Hits	20
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

TTK_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.020316 (rank : 25)
Query Neighborhood Hits	22	Target Neighborhood Hits	816	Shared Neighborhood Hits	17
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

AL2S2_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.035096 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	727	Shared Neighborhood Hits	18
SwissProt Accessions	Q9C0K7, Q5BKY7, Q9P1L0	Gene names	ALS2CR2, ILPIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (ILP- interacting protein) (CALS-21).

M3K8_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.036353 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	815	Shared Neighborhood Hits	20
SwissProt Accessions	Q07174	Gene names	Map3k8, Cot
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene).

YSK4_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.034565 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	921	Shared Neighborhood Hits	20
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

STK24_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.038146 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	853	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6E0, O14840	Gene names	STK24, MST3, STK3
Domain Architecture
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3).

STK24_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.038117 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	856	Shared Neighborhood Hits	20
SwissProt Accessions	Q99KH8	Gene names	Stk24
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1).

STK25_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.036529 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	853	Shared Neighborhood Hits	20
SwissProt Accessions	O00506, Q15522, Q5BJF1	Gene names	STK25, SOK1, YSK1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

STK25_MOUSE
θ value	5.27518 (rank : 17)	NC score	0.036378 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	851	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z2W1	Gene names	Stk25, Sok1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

TTK_MOUSE
θ value	5.27518 (rank : 18)	NC score	0.018976 (rank : 26)
Query Neighborhood Hits	22	Target Neighborhood Hits	803	Shared Neighborhood Hits	16
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

ABCB9_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.005487 (rank : 28)
Query Neighborhood Hits	22	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP78, Q96AB1, Q9P208	Gene names	ABCB9, KIAA1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (hABCB9).

AL2S2_MOUSE
θ value	6.88961 (rank : 20)	NC score	0.031507 (rank : 24)
Query Neighborhood Hits	22	Target Neighborhood Hits	709	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K4T3, Q6P922, Q8BU86, Q8BXK0, Q8K4T2	Gene names	Als2cr2, Papk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog) (ILP-interacting protein homolog) (Polyploidy-associated protein kinase).

M3K8_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.034436 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	807	Shared Neighborhood Hits	20
SwissProt Accessions	P41279, Q14275, Q9HC81	Gene names	MAP3K8, COT
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene).

PAK1_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.039594 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	878	Shared Neighborhood Hits	19
SwissProt Accessions	O88643	Gene names	Pak1, Paka
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A).

WNK1_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.062929 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	1158	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

WNK1_MOUSE
θ value	θ > 10 (rank : 24)	NC score	0.061916 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	1179	Shared Neighborhood Hits	16
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

WNK2_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.064453 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	1407	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

WNK3_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.068413 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	948	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

WNK4_HUMAN
θ value	θ > 10 (rank : 27)	NC score	0.065650 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	1043	Shared Neighborhood Hits	17
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

WNK4_MOUSE
θ value	θ > 10 (rank : 28)	NC score	0.063510 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	961	Shared Neighborhood Hits	17
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

Hits sorted by NC score

NRBP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.62758e-142 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NSY0, Q597G7, Q8NCX8, Q8WYS5	Gene names	NRBP2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein 2 (Transformation-related protein 16).

NRBP2_MOUSE
NC score	0.998039 (rank : 2)	θ value	5.23575e-141 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q91V36, Q8R3M0	Gene names	Nrbp2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein 2.

NRBP_MOUSE
NC score	0.493456 (rank : 3)	θ value	2.93355e-67 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	442	Shared Neighborhood Hits	16
SwissProt Accessions	Q99J45, Q8BL77	Gene names	Nrbp1, Madm, Nrbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein (MLF1 adapter molecule) (HLS7- interacting protein kinase).

NRBP_HUMAN
NC score	0.492834 (rank : 4)	θ value	5.00389e-67 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	448	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHY1, Q53FZ5, Q96SU3	Gene names	NRBP1, BCON3, NRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein.

WNK3_HUMAN
NC score	0.068413 (rank : 5)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	22	Target Neighborhood Hits	948	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

WNK4_HUMAN
NC score	0.065650 (rank : 6)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	22	Target Neighborhood Hits	1043	Shared Neighborhood Hits	17
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

WNK2_HUMAN
NC score	0.064453 (rank : 7)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	22	Target Neighborhood Hits	1407	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

WNK4_MOUSE
NC score	0.063510 (rank : 8)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	22	Target Neighborhood Hits	961	Shared Neighborhood Hits	17
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

WNK1_HUMAN
NC score	0.062929 (rank : 9)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	1158	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

WNK1_MOUSE
NC score	0.061916 (rank : 10)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	22	Target Neighborhood Hits	1179	Shared Neighborhood Hits	16
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

OXSR1_MOUSE
NC score	0.056193 (rank : 11)	θ value	0.000786445 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	865	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

OXSR1_HUMAN
NC score	0.048062 (rank : 12)	θ value	0.0961366 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	874	Shared Neighborhood Hits	20
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

PAK1_MOUSE
NC score	0.039594 (rank : 13)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	878	Shared Neighborhood Hits	19
SwissProt Accessions	O88643	Gene names	Pak1, Paka
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A).

MST4_MOUSE
NC score	0.039060 (rank : 14)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	860	Shared Neighborhood Hits	20
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

MST4_HUMAN
NC score	0.038941 (rank : 15)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	852	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P289, Q3ZB77, Q9BXC4	Gene names	MST4, MASK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase).

STK24_HUMAN
NC score	0.038146 (rank : 16)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	853	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6E0, O14840	Gene names	STK24, MST3, STK3
Domain Architecture
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3).

STK24_MOUSE
NC score	0.038117 (rank : 17)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	856	Shared Neighborhood Hits	20
SwissProt Accessions	Q99KH8	Gene names	Stk24
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1).

STK25_HUMAN
NC score	0.036529 (rank : 18)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	853	Shared Neighborhood Hits	20
SwissProt Accessions	O00506, Q15522, Q5BJF1	Gene names	STK25, SOK1, YSK1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

STK25_MOUSE
NC score	0.036378 (rank : 19)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	851	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z2W1	Gene names	Stk25, Sok1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

M3K8_MOUSE
NC score	0.036353 (rank : 20)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	815	Shared Neighborhood Hits	20
SwissProt Accessions	Q07174	Gene names	Map3k8, Cot
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene).

AL2S2_HUMAN
NC score	0.035096 (rank : 21)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	727	Shared Neighborhood Hits	18
SwissProt Accessions	Q9C0K7, Q5BKY7, Q9P1L0	Gene names	ALS2CR2, ILPIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (ILP- interacting protein) (CALS-21).

YSK4_HUMAN
NC score	0.034565 (rank : 22)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	921	Shared Neighborhood Hits	20
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

M3K8_HUMAN
NC score	0.034436 (rank : 23)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	807	Shared Neighborhood Hits	20
SwissProt Accessions	P41279, Q14275, Q9HC81	Gene names	MAP3K8, COT
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene).

AL2S2_MOUSE
NC score	0.031507 (rank : 24)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	709	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K4T3, Q6P922, Q8BU86, Q8BXK0, Q8K4T2	Gene names	Als2cr2, Papk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog) (ILP-interacting protein homolog) (Polyploidy-associated protein kinase).

TTK_HUMAN
NC score	0.020316 (rank : 25)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	816	Shared Neighborhood Hits	17
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

TTK_MOUSE
NC score	0.018976 (rank : 26)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	803	Shared Neighborhood Hits	16
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

STAB1_MOUSE
NC score	0.018310 (rank : 27)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	566	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

ABCB9_HUMAN
NC score	0.005487 (rank : 28)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP78, Q96AB1, Q9P208	Gene names	ABCB9, KIAA1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (hABCB9).