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Network neighborhood for query Sequence : NHEJ1_MOUSE

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NHEJ1_MOUSE
SwissProt Accessions	Q3KNJ2, Q99JK0, Q9D9U0	Gene names	Nhej1, Xlf
Domain Architecture	No domain graphic available
Description	Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NHEJ1_MOUSE
θ value	5.21151e-157 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q3KNJ2, Q99JK0, Q9D9U0	Gene names	Nhej1, Xlf
Domain Architecture	No domain graphic available
Description	Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor).

NHEJ1_HUMAN
θ value	4.60808e-121 (rank : 2)	NC score	0.988786 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H9Q4, Q4ZFW7, Q6IA64, Q96JS9	Gene names	NHEJ1, XLF
Domain Architecture	No domain graphic available
Description	Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor).

IRF8_MOUSE
θ value	0.279714 (rank : 3)	NC score	0.038659 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

MAPE_HUMAN
θ value	3.0926 (rank : 4)	NC score	0.018335 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P78395, O43481, Q8IXN8	Gene names	PRAME, MAPE
Domain Architecture	No domain graphic available
Description	Melanoma antigen preferentially expressed in tumors (Preferentially expressed antigen of melanoma) (OPA-interacting protein 4) (OIP4).

CGAT1_MOUSE
θ value	4.03905 (rank : 5)	NC score	0.018990 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJQ9, Q3UZX6, Q8BWV9, Q8BZU7, Q8C195, Q8R0M6	Gene names	Galnact1, Chgn
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

RFIP1_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.025199 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	236	Shared Neighborhood Hits	5
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SRRM2_HUMAN
θ value	5.27518 (rank : 7)	NC score	0.014234 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	1296	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYTL2_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.013328 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	248	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

MINT_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.012524 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	1291	Shared Neighborhood Hits	6
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ARHGB_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.008428 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	375	Shared Neighborhood Hits	2
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

M3K7_HUMAN
θ value	8.99809 (rank : 11)	NC score	0.001279 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	892	Shared Neighborhood Hits	2
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

PML_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.012870 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	246	Shared Neighborhood Hits	2
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

PPIG_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.007644 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	670	Shared Neighborhood Hits	5
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SOX12_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.006680 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

Hits sorted by NC score

NHEJ1_MOUSE
NC score	0.999962 (rank : 1)	θ value	5.21151e-157 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q3KNJ2, Q99JK0, Q9D9U0	Gene names	Nhej1, Xlf
Domain Architecture	No domain graphic available
Description	Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor).

NHEJ1_HUMAN
NC score	0.988786 (rank : 2)	θ value	4.60808e-121 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H9Q4, Q4ZFW7, Q6IA64, Q96JS9	Gene names	NHEJ1, XLF
Domain Architecture	No domain graphic available
Description	Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor).

IRF8_MOUSE
NC score	0.038659 (rank : 3)	θ value	0.279714 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

RFIP1_HUMAN
NC score	0.025199 (rank : 4)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	236	Shared Neighborhood Hits	5
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

CGAT1_MOUSE
NC score	0.018990 (rank : 5)	θ value	4.03905 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJQ9, Q3UZX6, Q8BWV9, Q8BZU7, Q8C195, Q8R0M6	Gene names	Galnact1, Chgn
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

MAPE_HUMAN
NC score	0.018335 (rank : 6)	θ value	3.0926 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P78395, O43481, Q8IXN8	Gene names	PRAME, MAPE
Domain Architecture	No domain graphic available
Description	Melanoma antigen preferentially expressed in tumors (Preferentially expressed antigen of melanoma) (OPA-interacting protein 4) (OIP4).

SRRM2_HUMAN
NC score	0.014234 (rank : 7)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	1296	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYTL2_HUMAN
NC score	0.013328 (rank : 8)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	248	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

PML_MOUSE
NC score	0.012870 (rank : 9)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	246	Shared Neighborhood Hits	2
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

MINT_HUMAN
NC score	0.012524 (rank : 10)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	1291	Shared Neighborhood Hits	6
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ARHGB_HUMAN
NC score	0.008428 (rank : 11)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	375	Shared Neighborhood Hits	2
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

PPIG_HUMAN
NC score	0.007644 (rank : 12)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	670	Shared Neighborhood Hits	5
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SOX12_MOUSE
NC score	0.006680 (rank : 13)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

M3K7_HUMAN
NC score	0.001279 (rank : 14)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	892	Shared Neighborhood Hits	2
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).