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Network neighborhood for query Sequence : NEUR4_MOUSE

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NEUR4_MOUSE
SwissProt Accessions	Q8BZL1	Gene names	Neu4
Domain Architecture
Description	Sialidase-4 (EC 3.2.1.18) (Neuraminidase 4) (N-acetyl-alpha- neuraminidase 4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NEUR4_HUMAN
θ value	0 (rank : 1)	NC score	0.990233 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWR8, Q96D64	Gene names	NEU4
Domain Architecture
Description	Sialidase-4 (EC 3.2.1.18) (N-acetyl-alpha-neuraminidase 4).

NEUR4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZL1	Gene names	Neu4
Domain Architecture
Description	Sialidase-4 (EC 3.2.1.18) (Neuraminidase 4) (N-acetyl-alpha- neuraminidase 4).

NEUR3_MOUSE
θ value	1.10445e-98 (rank : 3)	NC score	0.969506 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JMH7	Gene names	Neu3
Domain Architecture
Description	Sialidase-3 (EC 3.2.1.18) (Membrane sialidase) (Ganglioside sialidase) (N-acetyl-alpha-neuraminidase 3).

NEUR3_HUMAN
θ value	2.91321e-91 (rank : 4)	NC score	0.965212 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UQ49, Q9NQE1	Gene names	NEU3
Domain Architecture
Description	Sialidase-3 (EC 3.2.1.18) (Membrane sialidase) (Ganglioside sialidase) (N-acetyl-alpha-neuraminidase 3).

NEUR2_MOUSE
θ value	8.55514e-59 (rank : 5)	NC score	0.929214 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JMH3, Q99NA3	Gene names	Neu2
Domain Architecture
Description	Sialidase-2 (EC 3.2.1.18) (Cytosolic sialidase) (N-acetyl-alpha- neuraminidase 2) (Murine thymic sialidase) (MTS) (Mouse skeletal muscle sialidase) (MSS).

NEUR2_HUMAN
θ value	2.94719e-51 (rank : 6)	NC score	0.924804 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y3R4	Gene names	NEU2
Domain Architecture
Description	Sialidase-2 (EC 3.2.1.18) (Cytosolic sialidase) (N-acetyl-alpha- neuraminidase 2).

NEUR1_HUMAN
θ value	3.89403e-11 (rank : 7)	NC score	0.558267 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q99519	Gene names	NEU1, NANH
Domain Architecture
Description	Sialidase-1 precursor (EC 3.2.1.18) (Lysosomal sialidase) (N-acetyl- alpha-neuraminidase 1) (Acetylneuraminyl hydrolase) (G9 sialidase).

NEUR1_MOUSE
θ value	9.59137e-10 (rank : 8)	NC score	0.529113 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	O35657, O55220, Q99KG9	Gene names	Neu1, Neu
Domain Architecture
Description	Sialidase-1 precursor (EC 3.2.1.18) (Lysosomal sialidase) (N-acetyl- alpha-neuraminidase 1) (G9 sialidase).

IRAK1_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.004239 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	784	Shared Neighborhood Hits	2
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

FBX34_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.016683 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWN3, Q2VPB5, Q86TY4	Gene names	FBXO34, FBX34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

HIC1_MOUSE
θ value	6.88961 (rank : 11)	NC score	-0.000358 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	863	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

MLL2_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.003581 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	1788	Shared Neighborhood Hits	2
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

DMRTD_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.010121 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

Hits sorted by NC score

NEUR4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZL1	Gene names	Neu4
Domain Architecture
Description	Sialidase-4 (EC 3.2.1.18) (Neuraminidase 4) (N-acetyl-alpha- neuraminidase 4).

NEUR4_HUMAN
NC score	0.990233 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWR8, Q96D64	Gene names	NEU4
Domain Architecture
Description	Sialidase-4 (EC 3.2.1.18) (N-acetyl-alpha-neuraminidase 4).

NEUR3_MOUSE
NC score	0.969506 (rank : 3)	θ value	1.10445e-98 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JMH7	Gene names	Neu3
Domain Architecture
Description	Sialidase-3 (EC 3.2.1.18) (Membrane sialidase) (Ganglioside sialidase) (N-acetyl-alpha-neuraminidase 3).

NEUR3_HUMAN
NC score	0.965212 (rank : 4)	θ value	2.91321e-91 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UQ49, Q9NQE1	Gene names	NEU3
Domain Architecture
Description	Sialidase-3 (EC 3.2.1.18) (Membrane sialidase) (Ganglioside sialidase) (N-acetyl-alpha-neuraminidase 3).

NEUR2_MOUSE
NC score	0.929214 (rank : 5)	θ value	8.55514e-59 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JMH3, Q99NA3	Gene names	Neu2
Domain Architecture
Description	Sialidase-2 (EC 3.2.1.18) (Cytosolic sialidase) (N-acetyl-alpha- neuraminidase 2) (Murine thymic sialidase) (MTS) (Mouse skeletal muscle sialidase) (MSS).

NEUR2_HUMAN
NC score	0.924804 (rank : 6)	θ value	2.94719e-51 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y3R4	Gene names	NEU2
Domain Architecture
Description	Sialidase-2 (EC 3.2.1.18) (Cytosolic sialidase) (N-acetyl-alpha- neuraminidase 2).

NEUR1_HUMAN
NC score	0.558267 (rank : 7)	θ value	3.89403e-11 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q99519	Gene names	NEU1, NANH
Domain Architecture
Description	Sialidase-1 precursor (EC 3.2.1.18) (Lysosomal sialidase) (N-acetyl- alpha-neuraminidase 1) (Acetylneuraminyl hydrolase) (G9 sialidase).

NEUR1_MOUSE
NC score	0.529113 (rank : 8)	θ value	9.59137e-10 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	O35657, O55220, Q99KG9	Gene names	Neu1, Neu
Domain Architecture
Description	Sialidase-1 precursor (EC 3.2.1.18) (Lysosomal sialidase) (N-acetyl- alpha-neuraminidase 1) (G9 sialidase).

FBX34_HUMAN
NC score	0.016683 (rank : 9)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWN3, Q2VPB5, Q86TY4	Gene names	FBXO34, FBX34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

DMRTD_MOUSE
NC score	0.010121 (rank : 10)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

IRAK1_MOUSE
NC score	0.004239 (rank : 11)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	784	Shared Neighborhood Hits	2
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

MLL2_HUMAN
NC score	0.003581 (rank : 12)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	1788	Shared Neighborhood Hits	2
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

HIC1_MOUSE
NC score	-0.000358 (rank : 13)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	863	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).